All human and mice ORF clones and related Lentivirus, AAV particles and recombinant proteins provided by GeneCopoeia are fully sequenced using Sanger sequencing by capillary electrophoresis and Amino Acid Sequences are guaranteed to be matched with NCBI database.

Protease

Introduction

Proteases are widely distributed in animals, plants and microorganisms, and their main role is to catalyze the hydrolysis of proteins and peptides. Proteases play an important role in organisms, and their activities are tightly regulated and controlled, because the over-expression of proteases could be detrimental to the health of the organisms. Together, proteases and their inhibitors are involved in the regulation of many physiological responses in the organism, such as the human pancreatic rennet protease (CTRC) that regulates the balance between trypsin activation and hydrolysis, the HIV-1 protease that plays an important role in viral replication, and the extracellular matrix metalloproteinase MT1-MMP mutation that affects bone tissue development.

Proteases are key factors in cellular health and viability and are involved in a variety of physiological processes such as replication, transcription, cell proliferation, differentiation, remodeling of the extracellular matrix, and processing of hormones and bioactive peptides. Proteases are implicated in many diseases, such as cancer, Alzheimer’s disease, arthritis, clotting disorders, allergies and infections.

Clone set information

Cat. No.	Old Cat. No.	Species	Gene	Vector	Vector Type	Price
OC-GF018-M02	OC-HPR-M02	Human	596	pReceiver-M02	Expression-ready Non-viral	Inquire
OC-GF018-M35	OC-HPR-M35	Human	596	pReceiver-M35	Expression-ready Non-viral	Inquire
OC-GF018-M98	OC-HPR-M98	Human	596	pReceiver-M98	Expression-ready Non-viral	Inquire
OC-GF018-Lv105	OC-HPR-Lv105	Human	596	pReceiver-Lv105	Expression-ready Lentiviral	Inquire
OC-GF018-Lv242	OC-HPR-Lv242	Human	596	pReceiver-Lv242	Expression-ready Lentiviral	Inquire
OC-GF018-GC	OC-HPR-GC	Human	596	pDONR™ Vector	Gateway shuttle	Inquire

Clone list

The form only shows 50 clones of the whole set. Please contact us at 1-301-762-0888 or inquiry@genecopoeia.com if you have any questions.

Symbol	Accession	Species	Description	ORF length(bp)	Product ID
KLK13	NM_015596.3	Human	Homo sapiens kallikrein related peptidase 13 (KLK13), transcript variant 1, mRNA.	834	GC-T1297
IHH	NM_002181.3.01	Human	Homo sapiens indian hedgehog (IHH), mRNA. Codon-optimized for Homo sapiens.	1236	GC-X1015
PSEN1	NM_000021.4	Human	Homo sapiens presenilin 1 (PSEN1), transcript variant 1, mRNA.	1404	GC-Z0049
C2	NM_000063.6	Human	Homo sapiens complement C2 (C2), transcript variant 1, mRNA.	2259	GC-Z5855
TOR1A	NM_000113.3	Human	Homo sapiens torsin family 1 member A (TOR1A), mRNA.	999	GC-M0262
EPHX1	NM_000120.4	Human	Homo sapiens epoxide hydrolase 1 (EPHX1), transcript variant 1, mRNA.	1368	GC-V0551
F11	NM_000128.4	Human	Homo sapiens coagulation factor XI (F11), transcript variant 1, mRNA.	1878	GC-Q0319
F7	NM_000131.4	Human	Homo sapiens coagulation factor VII (F7), transcript variant 1, mRNA.	1401	GC-Q0320
F9	NM_000133.4	Human	Homo sapiens coagulation factor IX (F9), transcript variant 1, mRNA.	1386	GC-T0161
SHH	NM_000193.4	Human	Homo sapiens sonic hedgehog signaling molecule (SHH), transcript variant 1, mRNA.	1389	GC-T1004
CTSA	NM_000308.3	Human	Homo sapiens cathepsin A (CTSA), transcript variant 1, mRNA.	1497	GC-Z3990
PROC	NM_000312.4	Human	Homo sapiens protein C, inactivator of coagulation factors Va and VIIIa (PROC), transcript variant 10, mRNA.	1386	GC-D0023
BLMH	NM_000386.4	Human	Homo sapiens bleomycin hydrolase (BLMH), mRNA.	1368	GC-M0622
TPP1	NM_000391.4	Human	Homo sapiens tripeptidyl peptidase 1 (TPP1), mRNA.	1692	GC-Z5873
CTSK	NM_000396.3	Human	Homo sapiens cathepsin K (CTSK), mRNA.	990	GC-F0967
PCSK1	NM_000439.5	Human	Homo sapiens proprotein convertase subtilisin/kexin type 1 (PCSK1), transcript variant 1, mRNA.	2262	GC-A4410
PHEX	NM_000444.6	Human	Homo sapiens phosphate regulating endopeptidase homolog X-linked (PHEX), transcript variant 1, mRNA.	2250	GC-S0053
PSEN2	NM_000447.3	Human	Homo sapiens presenilin 2 (PSEN2), transcript variant 1, mRNA.	1347	GC-A3745
F10	NM_000504.4	Human	Homo sapiens coagulation factor X (F10), transcript variant 1, mRNA.	1467	GC-T0169
HGF	NM_000601.6	Human	Homo sapiens hepatocyte growth factor (HGF), transcript variant 1, mRNA.	2187	GC-A0820
ACE	NM_000789.4	Human	Homo sapiens angiotensin I converting enzyme (ACE), transcript variant 1, mRNA.	3921	GC-Y4341
LTA4H	NM_000895.3	Human	Homo sapiens leukotriene A4 hydrolase (LTA4H), transcript variant 1, mRNA.	1836	GC-C0282
PLAT	NM_000930.5	Human	Homo sapiens plasminogen activator, tissue type (PLAT), transcript variant 1, mRNA.	1689	GC-F0362
DDI1	NM_001001711.3	Human	Homo sapiens DNA damage inducible 1 homolog 1 (DDI1), mRNA.	1191	GC-H3316
MGLL	NM_001003794.3	Human	Homo sapiens monoglyceride lipase (MGLL), transcript variant 2, mRNA.	912	GC-Z2584
PRSS37	NM_001008270.3	Human	Homo sapiens serine protease 37 (PRSS37), transcript variant 1, mRNA.	708	GC-Y5227
PM20D2	NM_001010853.3	Human	Homo sapiens peptidase M20 domain containing 2 (PM20D2), mRNA.	1311	GC-Y3611
HGF	NM_001010931.3	Human	Homo sapiens hepatocyte growth factor (HGF), transcript variant 2, mRNA.	873	GC-Z3545
HGF	NM_001010932.3	Human	Homo sapiens hepatocyte growth factor (HGF), transcript variant 3, mRNA.	2172	GC-Z4094
HGF	NM_001010933.3	Human	Homo sapiens hepatocyte growth factor (HGF), transcript variant 4, mRNA.	858	GC-Z3546
HGF	NM_001010934.3	Human	Homo sapiens hepatocyte growth factor (HGF), transcript variant 5, mRNA.	633	GC-Z3547
FOLH1	NM_001014986.3	Human	Homo sapiens folate hydrolase 1 (FOLH1), transcript variant 2, mRNA.	2160	GC-Z0516
MMP28	NM_001032278.3	Human	Homo sapiens matrix metallopeptidase 28 (MMP28), transcript variant 3, mRNA.	393	GC-Z3592
RCE1	NM_001032279.2	Human	Homo sapiens Ras converting CAAX endopeptidase 1 (RCE1), transcript variant 2, mRNA.	678	GC-Z3153
KYNU	NM_001032998.2	Human	Homo sapiens kynureninase (KYNU), transcript variant 2, mRNA.	924	GC-Z1983
AGBL5	NM_001035507.3	Human	Homo sapiens AGBL carboxypeptidase 5 (AGBL5), transcript variant 3, mRNA.	2154	GC-H1528
USP14	NM_001037334.2	Human	Homo sapiens ubiquitin specific peptidase 14 (USP14), transcript variant 2, mRNA.	1380	GC-Z4209
PARL	NM_001037639.3	Human	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant 2, mRNA; nuclear gene for mitochondrial product.	990	GC-V0571
DPP6	NM_001039350.3	Human	Homo sapiens dipeptidyl peptidase like 6 (DPP6), transcript variant 3, mRNA.	2406	GC-Z4216
PEG10	NM_001040152.2	Human	Homo sapiens paternally expressed 10 (PEG10), transcript variant 1, mRNA.	978	GC-W0145
TYSND1	NM_001040273.3	Human	Homo sapiens trypsin like peroxisomal matrix peptidase 1 (TYSND1), transcript variant 2, mRNA.	1197	GC-H3414
ERAP1	NM_001040458.3	Human	Homo sapiens endoplasmic reticulum aminopeptidase 1 (ERAP1), transcript variant 2, mRNA.	2826	GC-W0353
SPPL2B	NM_001077238.2	Human	Homo sapiens signal peptide peptidase like 2B (SPPL2B), transcript variant 3, mRNA.	1536	GC-H0815
CASP8	NM_001080125.2	Human	Homo sapiens caspase 8 (CASP8), transcript variant G, mRNA.	1617	GC-Z4310
MYSM1	NM_001085487.3	Human	Homo sapiens Myb like, SWIRM and MPN domains 1 (MYSM1), mRNA.	2487	GC-E2363
USP5	NM_001098536.2	Human	Homo sapiens ubiquitin specific peptidase 5 (USP5), transcript variant 1, mRNA.	2577	GC-U0130
PSMB11	NM_001099780.2	Human	Homo sapiens proteasome subunit beta 11 (PSMB11), mRNA.	903	GC-H1203
GGT5	NM_001099781.2	Human	Homo sapiens gamma-glutamyltransferase 5 (GGT5), transcript variant 1, mRNA.	1764	GC-Z6119
GGT5	NM_001099782.2	Human	Homo sapiens gamma-glutamyltransferase 5 (GGT5), transcript variant 3, mRNA.	1665	GC-Z6120
SENP6	NM_001100409.3	Human	Homo sapiens SUMO specific peptidase 6 (SENP6), transcript variant 2, mRNA.	3318	GC-Z0540