All human and mice ORF clones and related Lentivirus, AAV particles and recombinant proteins provided by GeneCopoeia are fully sequenced using Sanger sequencing by capillary electrophoresis and Amino Acid Sequences are guaranteed to be matched with NCBI database.

Protease

Introduction

Proteases are widely distributed in animals, plants and microorganisms, and their main role is to catalyze the hydrolysis of proteins and peptides. Proteases play an important role in organisms, and their activities are tightly regulated and controlled, because the over-expression of proteases could be detrimental to the health of the organisms. Together, proteases and their inhibitors are involved in the regulation of many physiological responses in the organism, such as the human pancreatic rennet protease (CTRC) that regulates the balance between trypsin activation and hydrolysis, the HIV-1 protease that plays an important role in viral replication, and the extracellular matrix metalloproteinase MT1-MMP mutation that affects bone tissue development. Proteases are key factors in cellular health and viability and are involved in a variety of physiological processes such as replication, transcription, cell proliferation, differentiation, remodeling of the extracellular matrix, and processing of hormones and bioactive peptides. Proteases are implicated in many diseases, such as cancer, Alzheimer’s disease, arthritis, clotting disorders, allergies and infections.

Clone set information

Cat. no.	Species	Gene	Vector	Vector Type	Price
OC-HPR-M02	Human	596	pReceiver-M02	Expression-ready Non-viral	Inquire
OC-HPR-M35	Human	596	pReceiver-M35	Expression-ready Non-viral	Inquire
OC-HPR-M98	Human	596	pReceiver-M98	Expression-ready Non-viral	Inquire
OC-HPR-Lv105	Human	596	pReceiver-Lv105	Expression-ready Lentiviral	Inquire
OC-HPR-Lv242	Human	596	pReceiver-Lv242	Expression-ready Lentiviral	Inquire
OC-HPR-GC	Human	596	pDONR™ Vector	Gateway shuttle	Inquire

Clone list

The form only shows 50 clones of the whole set. Please contact us at 1-301-762-0888 or inquiry@genecopoeia.com if you have any questions.

Symbol	Accession	Species	Description	ORF length(bp)	Product ID
ADAM17	NM_003183.5	Human	Homo sapiens ADAM metallopeptidase domain 17 (ADAM17), mRNA.	2475	GC-Z8314
IDE	NM_004969.4	Human	Homo sapiens insulin degrading enzyme (IDE), transcript variant 1, mRNA.	3060	GC-A0272
BMP1	NM_001199.4	Human	Homo sapiens bone morphogenetic protein 1 (BMP1), transcript variant 1, mRNA.	2193	GC-A0384
CMA1	NM_001836.5	Human	Homo sapiens chymase 1 (CMA1), transcript variant 1, mRNA.	744	GC-A0570
HGF	NM_000601.6	Human	Homo sapiens hepatocyte growth factor (HGF), transcript variant 1, mRNA.	2187	GC-A0820
BIRC2	NM_001256163.1	Human	Homo sapiens baculoviral IAP repeat containing 2 (BIRC2), transcript variant 2, mRNA.	1857	GC-B0151
ENO1	NM_001428.5	Human	Homo sapiens enolase 1 (ENO1), transcript variant 1, mRNA.	1305	GC-C0061
UQCRC2	NM_003366.4	Human	Homo sapiens ubiquinol-cytochrome c reductase core protein 2 (UQCRC2), mRNA; nuclear gene for mitochondrial product.	1362	GC-C0188
LTA4H	NM_000895.3	Human	Homo sapiens leukotriene A4 hydrolase (LTA4H), transcript variant 1, mRNA.	1836	GC-C0282
THOP1	NM_003249.5	Human	Homo sapiens thimet oligopeptidase 1 (THOP1), mRNA.	2070	GC-C0488
UQCRC1	NM_003365.3	Human	Homo sapiens ubiquinol-cytochrome c reductase core protein 1 (UQCRC1), mRNA; nuclear gene for mitochondrial product.	1443	GC-C0542
PROC	NM_000312.4	Human	Homo sapiens protein C, inactivator of coagulation factors Va and VIIIa (PROC), transcript variant 10, mRNA.	1386	GC-D0023
CTSV	NM_001333.4	Human	Homo sapiens cathepsin V (CTSV), transcript variant 1, mRNA.	1005	GC-E0001
CAPN2	NM_001748.4	Human	Homo sapiens calpain 2 (CAPN2), transcript variant 1, mRNA.	2103	GC-E0074
QPCT	NM_012413.4	Human	Homo sapiens glutaminyl-peptide cyclotransferase (QPCT), mRNA.	1086	GC-E0292
ADAMTS15	NM_139055.4	Human	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 15 (ADAMTS15), mRNA.	2853	GC-E0438
CPO	NM_173077.3	Human	Homo sapiens carboxypeptidase O (CPO), mRNA.	1125	GC-E0472
LONP2	NM_031490.5	Human	Homo sapiens lon peptidase 2, peroxisomal (LONP2), transcript variant 1, mRNA.	2559	GC-E1718
USP37	NM_020935.2	Human	Homo sapiens ubiquitin specific peptidase 37 (USP37), mRNA.	2940	GC-E1856
PCSK6	NM_002570.5	Human	Homo sapiens proprotein convertase subtilisin/kexin type 6 (PCSK6), transcript variant 1, mRNA.	2910	GC-F0024
CASP1	NM_001257118.3	Human	Homo sapiens caspase 1 (CASP1), transcript variant 6, mRNA.	1215	GC-F0035
CTSE	NM_001910.4	Human	Homo sapiens cathepsin E (CTSE), transcript variant 1, mRNA.	1191	GC-F0059
CTSD	NM_001909.5	Human	Homo sapiens cathepsin D (CTSD), mRNA.	1239	GC-F0069
PLAU	NM_002658.4	Human	Homo sapiens plasminogen activator, urokinase (PLAU), transcript variant 1, mRNA.	1296	GC-F0073
CELA2A	NM_033440.3	Human	Homo sapiens chymotrypsin like elastase 2A (CELA2A), mRNA.	810	GC-F0075
DPP4	NM_001935.4	Human	Homo sapiens dipeptidyl peptidase 4 (DPP4), transcript variant 1, mRNA.	2301	GC-F0106
KLK2	NM_005551.5	Human	Homo sapiens kallikrein related peptidase 2 (KLK2), transcript variant 1, mRNA.	786	GC-F0110
PCSK2	NM_002594.5	Human	Homo sapiens proprotein convertase subtilisin/kexin type 2 (PCSK2), transcript variant 1, mRNA.	1917	GC-F0126
DPEP1	NM_001128141.3	Human	Homo sapiens dipeptidase 1 (DPEP1), transcript variant 2, mRNA.	1236	GC-F0127
MMP8	NM_002424.3	Human	Homo sapiens matrix metallopeptidase 8 (MMP8), transcript variant 1, mRNA.	1404	GC-F0129
GZMH	NM_033423.5	Human	Homo sapiens granzyme H (GZMH), transcript variant 1, mRNA.	741	GC-F0137
ANPEP	NM_001150.3	Human	Homo sapiens alanyl aminopeptidase, membrane (ANPEP), transcript variant 1, mRNA.	2904	GC-F0169
ENDOU	NM_006025.4	Human	Homo sapiens endonuclease, poly(U) specific (ENDOU), transcript variant 2, mRNA.	1110	GC-F0178
MMP1	NM_002421.4	Human	Homo sapiens matrix metallopeptidase 1 (MMP1), transcript variant 1, mRNA.	1410	GC-F0186
CPN1	NM_001308.3	Human	Homo sapiens carboxypeptidase N subunit 1 (CPN1), mRNA.	1377	GC-F0189
PRSS3	NM_002771.3	Human	Homo sapiens protease, serine 3 (PRSS3), transcript variant 2, mRNA.	744	GC-F0190
HPN	NM_002151.2	Human	Homo sapiens hepsin (HPN), transcript variant 2, mRNA.	1254	GC-F0204
CAPN1	NM_001198868.2	Human	Homo sapiens calpain 1 (CAPN1), transcript variant 1, mRNA.	2145	GC-F0216
FURIN	NM_002569.4	Human	Homo sapiens furin, paired basic amino acid cleaving enzyme (FURIN), transcript variant 1, mRNA.	2385	GC-F0229
PSMA6	NM_002791.3	Human	Homo sapiens proteasome 20S subunit alpha 6 (PSMA6), transcript variant 1, mRNA.	741	GC-F0241
PSMB9	NM_002800.5	Human	Homo sapiens proteasome 20S subunit beta 9 (PSMB9), mRNA.	660	GC-F0246
CPA1	NM_001868.4	Human	Homo sapiens carboxypeptidase A1 (CPA1), mRNA.	1260	GC-F0257
MMP7	NM_002423.5	Human	Homo sapiens matrix metallopeptidase 7 (MMP7), mRNA.	804	GC-F0265
PSMA2	NM_002787.5	Human	Homo sapiens proteasome 20S subunit alpha 2 (PSMA2), mRNA.	705	GC-F0270
PSMA3	NM_152132.3	Human	Homo sapiens proteasome 20S subunit alpha 3 (PSMA3), transcript variant 2, mRNA.	747	GC-F0272
PSMA4	NM_002789.6	Human	Homo sapiens proteasome 20S subunit alpha 4 (PSMA4), transcript variant 1, mRNA.	786	GC-F0273
UCHL3	NM_006002.5	Human	Homo sapiens ubiquitin C-terminal hydrolase L3 (UCHL3), transcript variant 2, mRNA.	693	GC-F0304
TPSAB1	NM_003294.4	Human	Homo sapiens tryptase alpha/beta 1 (TPSAB1), mRNA.	828	GC-F0305
ELANE	NM_001972.4	Human	Homo sapiens elastase, neutrophil expressed (ELANE), mRNA.	804	GC-F0319
PLAT	NM_000930.5	Human	Homo sapiens plasminogen activator, tissue type (PLAT), transcript variant 1, mRNA.	1689	GC-F0362