All human and mice ORF clones and related Lentivirus, AAV particles and recombinant proteins provided by GeneCopoeia are fully sequenced using Sanger sequencing by capillary electrophoresis and Amino Acid Sequences are guaranteed to be matched with NCBI database.

Cytokines and cytokine receptors

Introduction

Cytokines (CK) are low molecular weight soluble proteins (5-20 kDa) induced in a variety of cells by immunogens, mitogens, or other stimuli, generally through binding to the corresponding cytokine receptor on the cell surface, and through signaling, causing changes in cellular gene transcription. Cytokines have a variety of functions such as regulating intrinsic and adaptive immunity, hematopoiesis, cell growth, APSC pluripotent cells, and repair of damaged tissues. Cytokines can be classified according to their main functions: interleukins (IL), colony-stimulating factor (CSF), interferon (IFN), tumor necrosis factor (TNF), transforming growth factor-β family (TGF-β family), growth factors (GF), and chemokine family. Most cytokine receptors (CK-R) are heterodimers or multimers consisting of two or more subunits, usually including a specific ligand-binding alpha chain and a beta chain involved in signaling. In the natural state, cytokine receptors exist mainly in two forms: membrane-bound cytokine receptors (mCK-R) and soluble cytokine receptors (sCK-R) present in body fluids such as serum. The complex biological activity of the cytokine is mediated primarily through binding to the corresponding mCK-R while sCK-R has a unique biological significance. Changes in sCK-R levels in relation to certain diseases have been increasingly emphasized by scholars, and some recombinant sCK-R genetically engineered products have been clinically validated.

Clone set information

Cat. no.	Species	Gene	Vector	Vector Type	Price
OC-HCC-M02	Human	423	pReceiver-M02	Expression-ready Non-viral	Inquire
OC-HCC-M35	Human	423	pReceiver-M35	Expression-ready Non-viral	Inquire
OC-HCC-M98	Human	423	pReceiver-M98	Expression-ready Non-viral	Inquire
OC-HCC-Lv105	Human	423	pReceiver-Lv105	Expression-ready Lentiviral	Inquire
OC-HCC-Lv242	Human	423	pReceiver-Lv242	Expression-ready Lentiviral	Inquire
OC-HCC-GC	Human	423	pDONR™ Vector	Gateway shuttle	Inquire

Clone list

The form only shows 50 clones of the whole set. Please contact us at 1-301-762-0888 or inquiry@genecopoeia.com if you have any questions.

Symbol	Accession	Species	Description	ORF length(bp)	Product ID
IFNA1	NM_024013.3	Human	Homo sapiens interferon alpha 1 (IFNA1), mRNA.	570	GC-A0001
PTN	NM_002825.7	Human	Homo sapiens pleiotrophin (PTN), transcript variant 1, mRNA.	507	GC-A0004
IL10	NM_000572.3	Human	Homo sapiens interleukin 10 (IL10), transcript variant 1, mRNA.	537	GC-A0007
KITLG	NM_000899.5	Human	Homo sapiens KIT ligand (KITLG), transcript variant b, mRNA.	822	GC-A0012
BMP5	NM_021073.4	Human	Homo sapiens bone morphogenetic protein 5 (BMP5), transcript variant 1, mRNA.	1365	GC-A0015
BMP6	NM_001718.6	Human	Homo sapiens bone morphogenetic protein 6 (BMP6), mRNA.	1542	GC-A0016
FGF7	NM_002009.4	Human	Homo sapiens fibroblast growth factor 7 (FGF7), mRNA.	585	GC-A0017
IL12B	NM_002187.3	Human	Homo sapiens interleukin 12B (IL12B), mRNA.	987	GC-A0033
IL12A	NM_000882.4	Human	Homo sapiens interleukin 12A (IL12A), transcript variant 1, mRNA.	762	GC-A0034
TGFB2	NM_001135599.4	Human	Homo sapiens transforming growth factor beta 2 (TGFB2), transcript variant 1, mRNA.	1329	GC-A0107
AREG	NM_001657.4	Human	Homo sapiens amphiregulin (AREG), mRNA.	759	GC-A0114
IFNA14	NM_002172.3	Human	Homo sapiens interferon alpha 14 (IFNA14), mRNA.	570	GC-A0136
IFNB1	NM_002176.4	Human	Homo sapiens interferon beta 1 (IFNB1), mRNA.	564	GC-A0137
IGF1	NM_000618.5	Human	Homo sapiens insulin like growth factor 1 (IGF1), transcript variant 4, mRNA.	462	GC-A0153
FGF3	NM_005247.4	Human	Homo sapiens fibroblast growth factor 3 (FGF3), mRNA.	720	GC-A0154
IL11	NM_000641.4	Human	Homo sapiens interleukin 11 (IL11), transcript variant 1, mRNA.	600	GC-A0158
IFNW1	NM_002177.3	Human	Homo sapiens interferon omega 1 (IFNW1), mRNA.	588	GC-A0159
IL5	NM_000879.3	Human	Homo sapiens interleukin 5 (IL5), mRNA.	405	GC-A0169
LTB	NM_002341.2	Human	Homo sapiens lymphotoxin beta (LTB), transcript variant 1, mRNA.	735	GC-A0170
IL4	NM_000589.4	Human	Homo sapiens interleukin 4 (IL4), transcript variant 1, mRNA.	462	GC-A0173
CCL1	NM_002981.2	Human	Homo sapiens C-C motif chemokine ligand 1 (CCL1), mRNA.	291	GC-A0176
IFNG	NM_000619.3	Human	Homo sapiens interferon gamma (IFNG), mRNA.	501	GC-A0177
CSF3	NM_172219.3	Human	Homo sapiens colony stimulating factor 3 (CSF3), transcript variant 2, mRNA.	615	GC-A0178
IL1A	NM_000575.5	Human	Homo sapiens interleukin 1 alpha (IL1A), transcript variant 1, mRNA.	816	GC-A0179
IL1B	NM_000576.3	Human	Homo sapiens interleukin 1 beta (IL1B), mRNA.	810	GC-A0180
INHBA	NM_002192.4	Human	Homo sapiens inhibin subunit beta A (INHBA), mRNA.	1281	GC-A0186
BMP2	NM_001200.4	Human	Homo sapiens bone morphogenetic protein 2 (BMP2), mRNA.	1191	GC-A0241
BMP4	NM_001347916.1	Human	Homo sapiens bone morphogenetic protein 4 (BMP4), transcript variant 8, mRNA.	1227	GC-A0242
CXCL2	NM_002089.4	Human	Homo sapiens C-X-C motif chemokine ligand 2 (CXCL2), mRNA.	324	GC-A0267
TNF	NM_000594.4	Human	Homo sapiens tumor necrosis factor (TNF), mRNA.	702	GC-A0276
PDGFA	NM_002607.6	Human	Homo sapiens platelet derived growth factor subunit A (PDGFA), transcript variant 1, mRNA.	636	GC-A0278
IL6	NM_000600.5	Human	Homo sapiens interleukin 6 (IL6), transcript variant 1, mRNA.	639	GC-A0301
BMP7	NM_001719.3	Human	Homo sapiens bone morphogenetic protein 7 (BMP7), mRNA.	1296	GC-A0309
CCN2	NM_001901.2	Human	Homo sapiens connective tissue growth factor (CTGF), mRNA.	1050	GC-A0312
IL1RN	NM_173842.3	Human	Homo sapiens interleukin 1 receptor antagonist (IL1RN), transcript variant 1, mRNA.	534	GC-A0332
TGFA	NM_001099691.3	Human	Homo sapiens transforming growth factor alpha (TGFA), transcript variant 2, mRNA.	480	GC-A0352
CXCL9	NM_002416.3	Human	Homo sapiens C-X-C motif chemokine ligand 9 (CXCL9), mRNA.	378	GC-A0353
FGF4	NM_002007.4	Human	Homo sapiens fibroblast growth factor 4 (FGF4), mRNA.	621	GC-A0368
BMP1	NM_001199.4	Human	Homo sapiens bone morphogenetic protein 1 (BMP1), transcript variant 1, mRNA.	2193	GC-A0384
IL2	NM_000586.4	Human	Homo sapiens interleukin 2 (IL2), mRNA.	462	GC-A0413
IFNA17	NM_021268.2	Human	Homo sapiens interferon alpha 17 (IFNA17), mRNA.	570	GC-A0454
CXCL12	NM_000609.7	Human	Homo sapiens C-X-C motif chemokine ligand 12 (CXCL12), transcript variant 2, mRNA.	282	GC-A0590
FGF8	NM_006119.6	Human	Homo sapiens fibroblast growth factor 8 (FGF8), transcript variant B, mRNA.	648	GC-A0640
NGF	NM_002506.3	Human	Homo sapiens nerve growth factor (NGF), mRNA.	726	GC-A0708
IL7	NM_000880.4	Human	Homo sapiens interleukin 7 (IL7), transcript variant 1, mRNA.	534	GC-A0790
MDK	NM_002391.6	Human	Homo sapiens midkine (MDK), transcript variant 3, mRNA.	432	GC-A0792
IFNA2	NM_000605.4	Human	Homo sapiens interferon alpha 2 (IFNA2), mRNA.	567	GC-A0813
HGF	NM_000601.6	Human	Homo sapiens hepatocyte growth factor (HGF), transcript variant 1, mRNA.	2187	GC-A0820
FGF1	NM_001257209.1	Human	Homo sapiens fibroblast growth factor 1 (FGF1), transcript variant 11, mRNA.	468	GC-A0853
IL17A	NM_002190.3	Human	Homo sapiens interleukin 17A (IL17A), mRNA.	468	GC-A0895