GeneHero™ CRISPRa Stable Cell Lines are mammalian cell lines stably expressing synergistic activation mediators (SAM) for the study of transcriptional activation of endogenous genes. These CRISPRa cell lines have stably integrated human codon-optimized dCas9 fused at the C-terminus of transcriptional activator VP64, and activation helper protein complex MPH (MS2-p65-HSF1).
The cell lines are monoclonal with verified dCas9-VP64/MPH genome integration and expression. Simply introduce promoter-targeting sgRNA or CRISPRa sgRNA libraries into the CRISPRa cell lines. They are ideal for the study of gene expression activation and genetic screening. | ![]() |
Order information
Disclaimer: Pricing for premade cell lines are for customers in the US and Canada only. International customers, please contact your local distributor for pricing. To obtain the datasheet for each cell line, please click on the designated catalog number.
We also offer custom services for:
- Custom CRISPRa cell lines
- CRISPRa sgRNA
Contact us at inquiry@genecopoeia.com, or call 301-762-0888 for a quote.