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AAVPrime™ Adeno-associated Virus (AAV)

20% off Custom AAV*
Ends November 30, 2023

GeneCopoeia’s AAVPrime™ Adeno-associated virus (AAV) products are the ideal tools for expressing or modifying genes in a broad range of cell and tissue types, especially in vivo, with high efficiency and enhanced safety. GeneCopoeia’s optimized helper-free human AAV system allows viral packaging without potentially pathogenic helper adenovirus. Many pre-made AAV are available in 12 different serotypes, such as fluorescent reporters. You can also request us to produce custom AAV for genes up to 3 kb in length.

  • High titers. Titers of purified AAV particles can be up to 1014 GC/ml.
  • High adaptability. Virtually all serotypes are available.
  • Versatile. Usable in a broad range of host cell and tissue types.
  • Low toxicity. Does not integrate into the host genome.
  • Low immunogenicity. Minimal host immune response.
  • Safe. Not associated with any human disease
Search all AAV products by gene ID or accession number

Custom AAV

We offer AAV of virtually all serotypes with titers starting from 5×1012 GC/ml packaged with ORF cDNA, CRISPR/Cas9 or shRNA. Click the links below to search for your gene(s) of interest.

For custom AAV packaging service, please contact us at inquiry@genecopoeia.com to get a quote.

AAV-ORF cDNA

Choose from our collection of AAV vectors with different promoters and fluorescent markers for your gene expression. The AAV can be packaged with ORF cDNA clones up to 3 kb in length for long-term expression.

AAV Vector List

Vector name Promoter Promoter description Reporter gene Max length of insertion
pEZ-AV01 CMV Strong promoter, broad scope of application. N/A 2.4 kb
pEZ-AV02 EF-1α Broad scope of application. Better choice than CMV for in vivo applications. N/A 3.2 kb
pEZ-AV04 CAG Ubiquitous. Better choice than CMV for in vivo applications. N/A 2 kb
pEZ-AV06 CBh Hybrid chicken beta actin promoter. Provides better long-term expression than CMV in neural cells. N/A 2.8 kb
pEZ-AV07 CMV Strong promoter, broad scope of application. IRES-eGFP 1.3 kb
pEZ-AV08 EF-1α Broad scope of application. Better choice than CMV for in vivo applications. IRES-eGFP 2 kb
pEZ-AV09 CAG Ubiquitous. Better choice than CMV for in vivo applications. IRES-eGFP 0.9 kb
pEZ-AV11 CBh Hybrid chicken beta actin promoter. Provides better long-term expression than CMV in neural cells. IRES-eGFP 1.7 kb
pEZ-AV12 CAMKlla Highly specific expression in excitatory neurons in the neocortex and hippocampus. N/A 2.4 kb
pEZ-AV13 hSYN Human synapsin-1 gene promoter, neuronal-specific. N/A 3.2 kb
pEZ-AV15 MHC Muscle-specific human promoter. N/A 3.3 kb
pEZ-AV18 MCK Cardiac muscle-specific human promoter. N/A 3.0 kb
pEZ-AV24 MBP Oligodendrocyte-specific expression in central nervous system. N/A 3.0 kb
pEZ-AV33 ALB Liver-specific human promoter. N/A 2.0 kb

AAV-CRISPR

We offer AAV packaged with

  • SaCas9 and sgRNA in all-in-one vector
  • sgRNA only (for SpCas9 or SaCas9)
  • SpCas9 or SaCas9 only coming soon

AAV CRISPR Vectors

Vector name CRISPR Description Reporter gene
pCRISPR-AD01 SaCas9 & sgRNA All-in-one AAV vector with SaCas9 and sgRNA N/A
pCRISPR-AV20 sgRNA only AAV vector expressing sgRNA driven by U6 promoter N/A

AAV-shRNA

Transduction-ready AAV delivering shRNA of varying lengths (19 to 29 bases) that were designed using a proprietary algorithm to make shRNA expression constructs that have high knockdown efficiency with minimal off-target effect.

Vector Promoter Selection Marker Reporter Gene Viral type
psi-AV03 U6 N/A N/A AAV
psi-AVE001 CMV N/A eGFP AAV
psi-AVE002 CMV N/A mCherry AAV
psi-AVE003 EF1a N/A eGFP AAV
psi-AVE004 EF1a N/A mCherry AAV

 

Request a quote for custom pol III or pol II promoter-driven shRNA AAV services.

AAV-miRNA

Transduction-ready AAV delivering miRNA inhibitors or precursors.

miRNA Precursor AAV particles
Vector
Tracking gene
Selection marker
Promoter
Type
pEZX-MR14 eGFP Puromycin CMV AAV
pEZX-MR15 mCherry Puromycin CMV AAV
 

 

miRNA Inhibitor AAV particles
Vector
Tracking gene
Selection marker
Promoter
Type
pEZX-AM06 mCherry Hygromycin H1 AAV
pEZX-AM07 mCherry Hygromycin U6 AAV
 

Please contact inquiry@genecopoeia.com regarding miRNA cloning and AAV packaging services.

* Promotion is valid in the US & Canada only. For international customers, please contact your local distributors. Discount is applicable on large volume 400ul and 1ml. Discounts are not valid on particles that require gene synthesis or custom modification services. Discounts are not valid on previous purchases and cannot be combined with additional discounts.