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Human Autoantigens General Survey Microarray

Autoimmune diseases occur when the immune system, which normally does not attack a person's own components, produces self-reacting T-cells or circulating antibodies that recognize host proteins, also known as autoantigens. Over 100 autoimmune diseases have been described, creating a critical need for tools that can detect large numbers of autoantibodies with high sensitivity.

GeneCopoeia’s OmicsArray™ Human Autoantigens General Survey Antigen Microarray is a protein microarray enabling powerful detection of autoantibodies associated with many diseases, including rheumatoid arthritis, muscular dystrophy, systemic lupus erythematosus, and type 1 diabetes. The array carries 123 superior-quality purified proteins spotted onto nitrocellulose filters, which are adhered to glass slides. Antigens known to be associated with specific autoimmune diseases are chosen based on a thorough review of peer-reviewed publications.

In addition to this predesigned array, arrays containing customized sets of proteins are available, as well as array profiling services and data analysis.

GeneCopoeia’s OmicsArray™ Human Autoantigens General Survey Antigen Microarray is part of the GeneCopoeia OmicsArray™ Antigen Microarray family.

Advantages
  • Multiplexing capable.  OmicsArray™ antigen microarrays can assay up to 120 antigens at a time, compared with 1 protein at a time for ELISA.
  • High throughput.  Each slide can process up to 15 samples in parallel.
  • High sensitivity. Each array can detect as little as 1 pg/ml of antibody, which is 100-fold more sensitive than ELISA.
  • Small sample volume. As little as 1 ul of serum is needed for detection.
  • Fast. From sample-to-data in as little as 2 weeks.

Predesigned array

Predesigned antigen microarray

GeneCopoeia’s OmicsArray™ Autoantigens General Survey Antigen Microarray is a predesigned protein microarray carrying 123 antigens.

To view the list of antigens on this array, download the Excel file.

Custom protein microarrays are also available. To inquire about a custom protein microarray, please contact inquiry@genecopoeia.com.