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Brain and Central Nervous System Disorders Antigen Microarray

GeneCopoeia’s OmicsArray™ Brain and Central Nervous System Disorders Antigen Microarray is a powerful tool for detection of antibodies associated with neurological diseases. The array carries 69 superior-quality purified proteins, spotted onto nitrocellulose filters, which are adhered to glass slides, that are known antigens in central nervous system diseases. Antigens known to be associated with specific diseases are chosen based on a thorough review of peer-reviewed publications.

In addition to this predesigned array, arrays containing customized sets of proteins are available, as well as array profiling services and data analysis.

GeneCopoeia’s OmicsArray™ Brain and Central Nervous System Disorders Antigen Microarray is part of the GeneCopoeia OmicsArray™ Antigen Microarray family.

Advantages
  • Multiplexing capable.  OmicsArray™ antigen microarrays can assay up to 120 proteins at a time, compared with 1 protein at a time for ELISA.
  • High throughput.  Each slide can process up to 15 samples in parallel.
  • High sensitivity. Each array can detect as little as 1 pg/ml of antibody, which is 100-fold more sensitive than ELISA.
  • Small sample volume. As little as 1 ul of serum is needed for detection.
  • Fast. From sample-to-data in as little as 2 weeks.

Predesigned array

Predesigned antigen microarray

GeneCopoeia’s OmicsArray™ Brain and Central Nervous System Disorders Antigen Microarray is a predesigned antigen microarray. A partial list of the antigens spotted on this array are indicated in Table 1, under "Product Details". Custom antigen microarrays are also available. To inquire about a custom antigen microarray, please contact inquiry@genecopoeia.com.

Product Details

 

Antigen
Oligodendrocyte specific protein (OSP)
abCrystallin (CRYAB)
CRMP5 (collapsing response mediator protein 5)
Glial fibrillary acidic protein
PNMA2 (Human) Recombinant Protein (P01)
ITPR1 (Human) Recombinant Protein (Q01)
Epstein–Barr virus nuclear antigen 1
myelin-associated oligodendrocyte basic protein (MOBP)
N-methyl-D-aspartate-receptor subunit-NR1
synapsin 1
Glutamate dehydrogenase
Homer Homolog 3 (Drosophila) (HOMER3) (AA 1-361), (full length) protein (GST tag)
ELAV-like neuronal protein 1
14-3-3 – Alpha/Beta
Glutamate Metabotropic Receptor 1
potassium voltage-gated channel subfamily J member 10
Solute Carrier Family 1 Member 2
GJA1/CX43 /Connexin 43 Protien LS-G11926
ELAV-like protein 3
Zinc finger protein ZIC 4 (ZIC4)

 

Table 1. Partial list of proteins on GeneCopoeia's Brain and Central Nervous System Disorders Antigen Microarray.