Oct4 transcriptional response element (TRE) clone

Oct4 transcriptional response element(TRE) clone for Oct4 signaling pathway
Oct4 transcriptional response element(TRE) clone for Oct4 signaling pathway
Transcriptional response element(TRE) negative control clone
Transcriptional response element(TRE) negative control clone
GAPDH positive control clone
GAPDH positive control clone
Secreted alkaline phosphatase (SEAP)<br />Expression clone
Secreted alkaline phosphatase (SEAP)
Expression clone

Oct4 transcriptional response element(TRE) clone for Oct4 signaling pathway Transcriptional response element(TRE) negative control clone GAPDH positive control clone Secreted alkaline phosphatase (SEAP)
Expression clone

Price: $350.00 $350.00 $375.00 $395.00
Catalog#:
  • TR103
  • TR001
  • GAPDH-PG02
  • SEAP-PA01
Size: pEZX-PG02 pEZX-PG02 pEZX-PG02 pEZX-PA01
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Introduction

GeneCopoeia’s GLuc-ON™ Oct4 transcriptional response element (TRE) clone enables analysis of the effects on genes regulated by octamer-binding transcription factor 4 (Oct4). Oct4 is a transcription factor necessary for maintaining embryonic stem cells in their undifferentiated state, and its misregulation is associated with cancer.

The GLuc-ON™ Oct4 TRE clone contains tandem repeats of an NFAT binding site upstream of a minimal promoter and secreted Gaussia luciferase reporter gene, which allows robust and sensitive analysis without lysing the cells.  The Oct4 response elements are engineered to provide strong activation with low background (Figure 1). The GLuc-ON™ Oct4 TRE clone is provided as transfection-ready DNA. Negative (non-activating), positive (constitutively-activted) and normalization (secreated alkaline phosphatase) control clones are also available for purchase.