COVID-19 Coronavirus Receptor Stable Cell Lines

General informationGeneCopoeia has produced HEK293T cell lines expressing ACE2 and TMPRSS2, two human host factors needed for efficient infection by SARS-CoV-2, the virus responsible for the COVID-19 pandemic.

These cell lines express ACE2 and/or TMPRSS2 mRNA at high levels on the cell surface, and are amenable to infection by viruses expressing SARS-CoV-2 Spike protein in their envelopes. Refer to the “Performance data” tab for more information.

ACE2-expressing cell lines are great for use with either native SARS-CoV-2 virus or SARS-CoV-2 Spike-pseudotyped lentiviruses for several applications, such as:

  • Vaccine development for prevention of infection by SARS-CoV-2 virus
  • Studying the efficacy and mechanism of neutralizing antibodies against SARS-CoV-2 virus
  • Development of antiviral therapeutic agents
  • Studying the mechanism of virus-receptor interaction

You can order these cell lines from the table below. To obtain the datasheet for each cell line, please click on the designated catalog number.

In addition to the products below, custom stable cell lines are also available. For more information, please contact

Buy Catalog # Cell line Description Cell type Selection marker Price, Academic Price, Industry
SL221 HEK293T HEK293T cells stably expressing human ACE2 (NM_021804.2), 2×106 cells Embryonic kidney Hygromycin $1395 $3995
SL222 HEK293T HEK293T cells stably expressing human ACE2 (NM_021804.2) and TMPRSS2 (NM_005656.3), 2×106 cells Embryonic kidney




$1795 $4795


Warranty statement and limited use license MSDS



For more information or to request a quote, please contact