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OncoSpot™ NGS Reference Standards

GeneCopoeia's OncoSpot™ NGS Reference Standards use highly characterized HCT116 cell lines, genetically modified with advanced genome editing technology to include clinically relevant cancer gene mutations, just as they occur in patient tumors. The engineered mutations represent SNVs and deletions; the cell lines are manufactured in an ISO9001 certified facility to ensure lot-to-lot stability and reproducibility.

The reference standards are in the formats of genomic DNA and formalin-fixed paraffin-embedded (FFPE). They are compatible with multiple genomic platforms, e.g. NGS, sanger sequencing and qPCR, and are ideal to determine the performance criteria of the workflows, including:

  • DNA isolation
  • NGS library construction
  • Sample preparation
  • Sequencing

The reference standards are ideal for NGS assay development, quality control and validation for detection limit, precision and accuracy.

Buy Catalog No. Product Name Size Format Description
RM001 Wild type Parental HCT116 Reference Standard 5 µg gDNA View Details
RM002 EGFR ∆E746-A750 Reference Standard 1 µg gDNA View Details
RM003 EGFR L858R Reference Standard 1 µg gDNA View Details
RM004 EGFR T790M Reference Standard 1 µg gDNA View Details
RM005 EGFR T790M, C797S Reference Standard 1 µg gDNA View Details
RM006 KRAS G13C Reference Standard 1 µg gDNA View Details
RM007 BRAF V600E Reference Standard 1 µg gDNA View Details
RM008 KIT D816V Reference Standard 1 µg gDNA View Details
RM009 AKT E17K Reference Standard 1 µg gDNA View Details
RM201 Wild type Parental HCT116 Reference Standard 1 scroll FFPE View Details
RM202 EGFR ∆E746-A750 Reference Standard 1 scroll FFPE View Details
RM203 EGFR L858R Reference Standard 1 scroll FFPE View Details
RM204 EGFR T790M Reference Standard 1 scroll FFPE View Details
RM205 EGFR T790M, C797S Reference Standard 1 scroll FFPE View Details
RM206 KRAS G13C Reference Standard 1 scroll FFPE View Details
RM207 BRAF V600E Reference Standard 1 scroll FFPE View Details
RM208 KIT D816V Reference Standard 1 scroll FFPE View Details
RM209 AKT E17K Reference Standard 1 scroll FFPE View Details
RM210 EGFR C797S Reference Standard 1 scroll FFPE View Details
RM211 KRAS G12D Reference Standard 1 scroll FFPE View Details
RM212 EGFR G719S Reference Standard 1 scroll FFPE View Details
RM213 KRAS G12C Reference Standard 1 scroll FFPE View Details