GeneCopoeia offers premade cancer model cell lines carrying diverse gene mutations commonly seen in tumor biomarkers, including EGFR, KRAS and BRAF in the MAPK pathway. The mutant cells are engineered based on the HCT116 cancer cell line, in which mutations are integrated either homozygously or heterozygously using CRISPR technology. These model cell lines can be used to enhance our understanding of cancer biology and the development of cancer therapies.
Choose from a list of premade cancer cell lines with your desired mutations. The mutant cell lines are provided along with the HCT116 wild type parental cell line.
Don’t see the mutant cell line you want? We also offer custom cell line service. Please contact us at email@example.com, or call 866-360-9531 or 301-762-0888 for a quote.