Resources

CRISPR-Cas9 Protein for Highly Efficient Genome Editing With Minimal Off-Target Activity

  Ed Davis, Ph.D. Introduction The Clustered, Regularly Interspaced, Short Palindromic Repeats (CRISPR) system is widely used for editing genes and modulating gene expression, thanks to its ease-of-d...

How To Choose a GeneCopoeia Luciferase System

  Ed Davis, Ph.D. Introduction Luciferase reporter systems are invaluable tools for several applications, including regulation of gene expression and high-throughput compound screening (reviewed in T...

Choosing Between Lentivirus and Adeno-associated Virus For DNA Delivery

  Ed Davis, Ph.D. Introduction Lentivirus and Adeno-associated virus (AAV) have proven invaluable for introducing genetic material into mammalian cells, either in culture or whole animals. Both sys...

Cas9 Stable Cell Lines: Powerful Tools for CRISPR sgRNA Library Screening and More

  Ed Davis, Ph.D. Introduction The CRISPR-Cas9 system for genome editing is rapidly transforming research in biology and medicine, due to its ease-of-design, efficiency, specificity, and relatively l...

Using GeneCopoeia FISH Probes in a CRISPR-mediated Genome Editing Workflow

  Qihong Xu, Meng Zhang, Xueming Xu, and Ed Davis Introduction Immortalized mammalian cell lines, while providing convenient model systems for biomedical and pharmaceutical research, often carr...

Genome Editing: Applications For GeneCopoeia CRISPR sgRNA Libraries

  Ed Davis, Ph.D. Biomedical researchers are enjoying a Renaissance in functional genomics, which aims to use a wealth of DNA sequence information—most notably, the complete sequence of the huma...

Genome Editing: HDR Donors For Gene Knockout, Mutagenesis, Tagging, and Safe Harbor Knock-in

  Ed Davis, Ph.D. Genome Editing—making specific changes at targeted genomic sites—is fundamentally important to researchers in biology and medicine (Bogdanove & Voytas, 201...

Lentivirus: That’s My MOI, and I’m Sticking To It

  Ed Davis, Ph.D. Introduction Lentiviral vectors have proven invaluable for introducing genetic material into mammalian cells, either in culture or whole animals (reviewed in Mátrai, et al....

ORF clones: many tags, many decisions

  Ed Davis, Ph.D. Introduction Fusion tagging-the practice of adding amino acids in-frame to one end of a native protein-is a well- established strategy for many applications, including ...

Genome Editing: Which Should I Choose, TALEN or CRISPR?

  Ed Davis, Ph.D. Introduction Genome Editing-the ability to make specific changes at targeted genomic sites-is of fundamental importance to researchers in biology and medicine (Bogdanov...

Genome Editing in Mammalian Cells: What Do I Do Next?

  Ed Davis, Ph.D. Genome Editing-the ability to make specific changes at targeted genomic sites-is of fundamental importance in biology and medicine (for reviews, see Bogdanove & Voytas, 2011; van...

CRISPR-Cas9 Specificity: Taming Off-target Mutagenesis

  Ed Davis, Ph.D. Abstract Genome Editing-the ability to make specific changes at targeted genomic sites in complex organisms-is of fundamental importance in biology and medicine (Bogdanove & Voy...

Genome Editing Technology From GeneCopoeia, Inc.

  Ed Davis, Ph.D. Abstract Genome Editing-the ability to make specific changes at targeted genomic sites-is fundamentally important to researchers in biology and medicine (Bogdanove &...

Knockout by TALEN or CRISPR vs. Knockdown by shRNA or siRNA

  Ed Davis, Ph.D. Recent advances in technologies for genome editing-the use of TALEN or CRISPR to make targeted, permanent changes to genes-have revolutionized molecular genetics. They have also pres...

GeneCopoeia Genome Editing Tools for Safe Harbor Integration in Mice and Humans

  Ed Davis, Liuqing Qian, Ruiqing lI, Junsheng Zhou, and Jinkuo Zhang Introduction The ability to introduce transgenes into biological systems, such as cultured cells or animals, is of f...

Technical and Application Notes

Blog  Adding Value to CRISPR through Cas9 Stable Cell Lines New Discoveries Using Lentiviral Vectors for Screening Cancer Cells Why You Should Use Commercially-Produced Lentivirus     CRISPR ...

Recorded Webinars

Title: Advanced Tools For COVID-19 Coronavirus Research From GeneCopoeia Presented Friday, June 19, 2020 The COVID-19 global pandemic, caused by the SARS-CoV-2 coronavirus, highlights an urgent need for diagnostic reag...

Warranty Statements and End-user License Agreements

Products Warranty Statements and End-user License Agreements cDNA clones ORF cDNA Expression Clones   ORFeome Collaboration Clones miRNA miTarget™ microRNA 3' U...

Brochures and Product Profiles

Product Line   cDNA clones: ORF cDNA Expression Clones   OmicsLink™ Expression-Ready ORF Clones miRNA: microRNA Solutions Lentiviral: Lentiviral So...

Choose a product category to view publications using GeneCopoeia solutions

COVID-19 Coronavirus Research Tools Antigen Protein Microarrays ORF cDNA Clone Collections Lentiviral Solutions AAV Products and Services Stable cell lines Promoter Reporter Clone Collections MicroRN...

Manuals, Protocols, and MSDS

Clone datasheets are typically emailed upon shipment. If you did not receive the datasheet(s) for your order, please check your spam or junk email and/or with the person who placed the order. You may also complete the following...

OmicsLink™ Expression-Ready ORF cDNA Vectors

Expression-ready so no further sub cloning necessary Sequence-verified and available for 40,000+ human and mouse genes Choices of 150+ expression vectors as listed in the tables below ...

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