JNK transcriptional response element (TRE) clone

JNK transcriptional response element(TRE) clone for SAPK/JNK signaling pathway
JNK transcriptional response element(TRE) clone for SAPK/JNK signaling pathway
Transcriptional response element(TRE) negative control clone
Transcriptional response element(TRE) negative control clone
GAPDH positive control clone
GAPDH positive control clone
Secreted alkaline phosphatase (SEAP)<br />Expression clone
Secreted alkaline phosphatase (SEAP)
Expression clone

JNK transcriptional response element(TRE) clone for SAPK/JNK signaling pathway Transcriptional response element(TRE) negative control clone GAPDH positive control clone Secreted alkaline phosphatase (SEAP)
Expression clone

Price: $350.00 $350.00 $375.00 $395.00
Catalog#:
  • TR105
  • TR001
  • GAPDH-PG02
  • SEAP-PA01
Size: pEZX-PG02 pEZX-PG02 pEZX-PG02 pEZX-PA01
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Introduction GeneCopoeia’s GLuc-ON™ JNK transcriptional response element (TRE) clone enables analysis of the effects on genes regulated by activator protein 1 (AP1). AP1 is a transcription factor complex comprised of the c-Fos and c-Jun family proteins,  and is necessary for signaling through the Stress-activated protein kinases (SAPK)/Jun amino-terminal kinases (JNK) (SAPK/JNK) pathway. The GLuc-ON™ JNK TRE clone contains tandem repeats of an AP1 binding site upstream of a minimal promoter and secreted Gaussia luciferase reporter gene, which allows robust and sensitive analysis without lysing the cells.  The number of AP1 response elements has been optimized to maximize the sensitivity and minimize background levels (Figure 1). The GLuc-ON™ JNK TRE clone is provided as transfection-ready DNA. Negative (non-activating), positive (constitutively-activted) and normalization (secreated alkaline phosphatase) control clones are also available for purchase.