All human and mice ORF clones and related Lentivirus, AAV particles and recombinant proteins provided by GeneCopoeia are fully sequenced using Sanger sequencing by capillary electrophoresis and Amino Acid Sequences are guaranteed to be matched with NCBI database.

Nuclear hormone receptors

Introduction

Nuclear hormone receptors refer to the target molecules of hormone action in the nucleus of the cell and belong to nuclear receptors. Steroid hormone receptors and non-steroid hormone receptors are collectively referred to as nuclear hormone receptors.

Type I Steroid Receptors include: the estrogen receptor (ER), androgen receptor (AR), progesterone receptor (PGR), and glucocorticoid receptor (GR). Type II Non-steroid Receptors include: the thyroid hormone receptor (THR), the retinoic acid receptor (RARα), the vitamin D receptor (VDR), and the peroxidase proliferator activated receptor gamma (PPARγ). Receptors different from those on the cell surface are also known as nuclear hormone receptors.

Unlike receptors on the cell surface, these receptors are found only in postnatal animals (e.g., nematodes, insects, and vertebrates), and are mostly trans-acting factors that, when combined with the corresponding hormones, bind to cis-acting elements of DNA and regulate gene transcription, thus playing an important role in growth and development, metabolism, cellular differentiation, and many physiological processes in the body. Dysfunction of such receptors will lead to a series of diseases such as cancer, infertility, obesity and diabetes.

Clone set information

Cat. No.	Old Cat. No.	Species	Gene	Vector	Vector Type	Price
OC-GF015-M02	OC-HNH-M02	Human	73	pReceiver-M02	Expression-ready Non-viral	Inquire
OC-GF015-M35	OC-HNH-M35	Human	73	pReceiver-M35	Expression-ready Non-viral	Inquire
OC-GF015-M98	OC-HNH-M98	Human	73	pReceiver-M98	Expression-ready Non-viral	Inquire
OC-GF015-Lv105	OC-HNH-Lv105	Human	73	pReceiver-Lv105	Expression-ready Lentiviral	Inquire
OC-GF015-Lv242	OC-HNH-Lv242	Human	73	pReceiver-Lv242	Expression-ready Lentiviral	Inquire
OC-GF015-GC	OC-HNH-GC	Human	73	pDONR™ Vector	Gateway shuttle	Inquire
OC-GF015-AV43 NEW!	/	Human	73	pEZ-AV43	Expression-ready AAV	Inquire
OC-GF015-AV31 NEW!	/	Human	73	pEZ-AV31-p40500	Expression-ready AAV	Inquire

Clone list

The form only shows 50 clones of the whole set. Please contact us at 1-301-762-0888 or inquiry@genecopoeia.com if you have any questions.

Symbol	Accession	Species	Description	ORF length(bp)	Product ID
AR	NM_000044.6	Human	Homo sapiens androgen receptor (AR), transcript variant 1, mRNA.	2763	GC-E2325
AR	NM_001011645.3	Human	Homo sapiens androgen receptor (AR), transcript variant 2, mRNA.	1167	GC-E2336
RORA	NM_002943.3.01	Human	Homo sapiens RAR-related orphan receptor A (RORA), transcript variant 3, mRNA. Codon-optimized for Homo sapiens.	1647	GC-X1016
RORA	NM_134260.2.01	Human	Homo sapiens RAR-related orphan receptor A (RORA), transcript variant 2, mRNA. Codon-optimized for Homo sapiens.	1671	GC-X1022
ESR1	NM_000125.3	Human	Homo sapiens estrogen receptor 1 (ESR1), transcript variant 1, mRNA.	1788	GC-A0322
NR3C1	NM_000176.3	Human	Homo sapiens nuclear receptor subfamily 3 group C member 1 (NR3C1), transcript variant 1, mRNA.	2334	GC-Z2515
GNRHR	NM_000406.3	Human	Homo sapiens gonadotropin releasing hormone receptor (GNRHR), transcript variant 1, mRNA.	987	GC-A0455
HNF4A	NM_000457.6	Human	Homo sapiens hepatocyte nuclear factor 4 alpha (HNF4A), transcript variant 2, mRNA.	1425	GC-Z2593
NR0B1	NM_000475.5	Human	Homo sapiens nuclear receptor subfamily 0 group B member 1 (NR0B1), mRNA.	1413	GC-A0573
GHRHR	NM_000823.4	Human	Homo sapiens growth hormone releasing hormone receptor (GHRHR), mRNA.	1272	GC-A0191
NR3C2	NM_000901.5	Human	Homo sapiens nuclear receptor subfamily 3 group C member 2 (NR3C2), transcript variant 1, mRNA.	2955	GC-I1658
PGR	NM_000926.4	Human	Homo sapiens progesterone receptor (PGR), transcript variant 2, mRNA.	2802	GC-Z5911
RARB	NM_000965.5	Human	Homo sapiens retinoic acid receptor beta (RARB), transcript variant 1, mRNA.	1347	GC-Z2800
RARG	NM_000966.6	Human	Homo sapiens retinoic acid receptor gamma (RARG), transcript variant 1, mRNA.	1365	GC-T0175
RORC	NM_001001523.2	Human	Homo sapiens RAR related orphan receptor C (RORC), transcript variant 2, mRNA.	1494	GC-T6988
PPARA	NM_001001928.4	Human	Homo sapiens peroxisome proliferator activated receptor alpha (PPARA), transcript variant 3, mRNA.	1407	GC-Z5927
VDR	NM_001017535.2	Human	Homo sapiens vitamin D receptor (VDR), transcript variant 2, mRNA.	1284	GC-A0043
VDR	NM_001017536.2	Human	Homo sapiens vitamin D receptor (VDR), transcript variant 3, mRNA.	1434	GC-Z9198
TSHR	NM_001018036.3	Human	Homo sapiens thyroid stimulating hormone receptor (TSHR), transcript variant 2, mRNA.	762	GC-Z3564
NR3C1	NM_001020825.2	Human	Homo sapiens nuclear receptor subfamily 3 group C member 1 (NR3C1), transcript variant 6, mRNA.	2229	GC-Z4144
NR3C1	NM_001024094.2	Human	Homo sapiens nuclear receptor subfamily 3 group C member 1 (NR3C1), transcript variant 7, mRNA.	2337	GC-A0857
RARA	NM_001024809.4	Human	Homo sapiens retinoic acid receptor alpha (RARA), transcript variant 2, mRNA.	1374	GC-Z1280
HNF4A	NM_001030003.3	Human	Homo sapiens hepatocyte nuclear factor 4 alpha (HNF4A), transcript variant 4, mRNA.	1329	GC-Z4166
NR2C1	NM_001032287.3	Human	Homo sapiens nuclear receptor subfamily 2 group C member 1 (NR2C1), transcript variant 2, mRNA.	1404	GC-Z1646
NPM1	NM_001037738.3	Human	Homo sapiens nucleophosmin 1 (NPM1), transcript variant 3, mRNA.	780	GC-Z2182
NR1I3	NM_001077469.3	Human	Homo sapiens nuclear receptor subfamily 1 group I member 3 (NR1I3), transcript variant 6, mRNA.	1023	GC-Z4288
NR1I3	NM_001077472.3	Human	Homo sapiens nuclear receptor subfamily 1 group I member 3 (NR1I3), transcript variant 9, mRNA.	975	GC-Z3646
NR1I3	NM_001077480.3	Human	Homo sapiens nuclear receptor subfamily 1 group I member 3 (NR1I3), transcript variant 2, mRNA.	1059	GC-Z3186
NR1I3	NM_001077482.3	Human	Homo sapiens nuclear receptor subfamily 1 group I member 3 (NR1I3), transcript variant 1, mRNA.	1074	GC-Z9950
NR2C1	NM_001127362.2	Human	Homo sapiens nuclear receptor subfamily 2 group C member 1 (NR2C1), transcript variant 3, mRNA.	1452	GC-Z6303
NR1H3	NM_001130101.3	Human	Homo sapiens nuclear receptor subfamily 1 group H member 3 (NR1H3), transcript variant 2, mRNA.	1164	GC-Z0276
NR1H3	NM_001130102.3	Human	Homo sapiens nuclear receptor subfamily 1 group H member 3 (NR1H3), transcript variant 3, mRNA.	1209	GC-Z5751
CRHR1	NM_001145146.2	Human	Homo sapiens corticotropin releasing hormone receptor 1 (CRHR1), transcript variant 1b, mRNA.	1335	GC-A0714
NR2F2	NM_001145155.2	Human	Homo sapiens nuclear receptor subfamily 2 group F member 2 (NR2F2), transcript variant 2, mRNA.	846	GC-Z1540
NR2F2	NM_001145156.1	Human	Homo sapiens nuclear receptor subfamily 2 group F member 2 (NR2F2), transcript variant 3, mRNA.	786	GC-Z5765
RARA	NM_001145301.3	Human	Homo sapiens retinoic acid receptor alpha (RARA), transcript variant 3, mRNA.	1389	GC-H0048
RARA	NM_001145302.3	Human	Homo sapiens retinoic acid receptor alpha (RARA), transcript variant 4, mRNA.	1098	GC-Z6969
NR1D2	NM_001145425.2	Human	Homo sapiens nuclear receptor subfamily 1 group D member 2 (NR1D2), transcript variant 2, mRNA.	1515	GC-Z5767
THRA	NM_001190918.2	Human	Homo sapiens thyroid hormone receptor alpha (THRA), transcript variant 3, mRNA.	1356	GC-Z0464
THRA	NM_001190919.2	Human	Homo sapiens thyroid hormone receptor alpha (THRA), transcript variant 4, mRNA.	1473	GC-A0835
NR4A1	NM_001202233.2	Human	Homo sapiens nuclear receptor subfamily 4 group A member 1 (NR4A1), transcript variant 3, mRNA.	1836	GC-A1310
NR4A1	NM_001202234.2	Human	Homo sapiens nuclear receptor subfamily 4 group A member 1 (NR4A1), transcript variant 4, mRNA.	1959	GC-A4501
PGR	NM_001202474.3	Human	Homo sapiens progesterone receptor (PGR), transcript variant 1, mRNA.	2310	GC-A1694
CRHR2	NM_001202475.1	Human	Homo sapiens corticotropin releasing hormone receptor 2 (CRHR2), transcript variant 2, mRNA.	1317	GC-Z9785
CRHR2	NM_001202481.1	Human	Homo sapiens corticotropin releasing hormone receptor 2 (CRHR2), transcript variant 3, mRNA.	1194	GC-Z9323
CRHR2	NM_001202482.2	Human	Homo sapiens corticotropin releasing hormone receptor 2 (CRHR2), transcript variant 4, mRNA.	1233	GC-Z9002
CRHR2	NM_001202483.2	Human	Homo sapiens corticotropin releasing hormone receptor 2 (CRHR2), transcript variant 5, mRNA.	1164	GC-Z9001
NR3C1	NM_001204258.2	Human	Homo sapiens nuclear receptor subfamily 3 group C member 1 (NR3C1), transcript variant 1, mRNA.	2256	GC-Z9019
NR3C1	NM_001204259.2	Human	Homo sapiens nuclear receptor subfamily 3 group C member 1 (NR3C1), transcript variant 1, mRNA.	2079	GC-Z9299
NR3C1	NM_001204260.2	Human	Homo sapiens nuclear receptor subfamily 3 group C member 1 (NR3C1), transcript variant 1, mRNA.	2067	GC-Z9260