Nuclear hormone receptors

Introduction

Nuclear hormone receptors refer to the target molecules of hormone action in the nucleus of the cell and belong to nuclear receptors. Steroid hormone receptors and non-steroid hormone receptors are collectively referred to as nuclear hormone receptors. Type I Steroid Receptors include: the estrogen receptor (ER), androgen receptor (AR), progesterone receptor (PGR), and glucocorticoid receptor (GR). Type II Non-steroid Receptors include: the thyroid hormone receptor (THR), the retinoic acid receptor (RARα), the vitamin D receptor (VDR), and the peroxidase proliferator activated receptor gamma (PPARγ). Receptors different from those on the cell surface are also known as nuclear hormone receptors. Unlike receptors on the cell surface, these receptors are found only in postnatal animals (e.g., nematodes, insects, and vertebrates), and are mostly trans-acting factors that, when combined with the corresponding hormones, bind to cis-acting elements of DNA and regulate gene transcription, thus playing an important role in growth and development, metabolism, cellular differentiation, and many physiological processes in the body. Dysfunction of such receptors will lead to a series of diseases such as cancer, infertility, obesity and diabetes.

Clone set information

Cat. no. Species Gene Vector Vector Type Price
OC-HNH-M02 Human 73 pReceiver-M02 Expression-ready Non-viral Inquire
OC-HNH-M35 Human 73 pReceiver-M35 Expression-ready Non-viral Inquire
OC-HNH-M98 Human 73 pReceiver-M98 Expression-ready Non-viral Inquire
OC-HNH-Lv105 Human 73 pReceiver-Lv105 Expression-ready Lentiviral Inquire
OC-HNH-Lv242 Human 73 pReceiver-Lv242 Expression-ready Lentiviral Inquire
OC-HNH-GC Human 73 pDONR™ Vector Gateway shuttle Inquire

Clone list

The form only shows 50 clones of the whole set. Please contact us at 1-301-762-0888 or inquiry@genecopoeia.com if you have any questions.
Symbol Accession Species Description ORF length(bp) Product ID
VDR NM_001017535.2 Human Homo sapiens vitamin D receptor (VDR), transcript variant 2, mRNA. 1284 GC-A0043
GHRHR NM_000823.4 Human Homo sapiens growth hormone releasing hormone receptor (GHRHR), mRNA. 1272 GC-A0191
ESR1 NM_000125.3 Human Homo sapiens estrogen receptor 1 (ESR1), transcript variant 1, mRNA. 1788 GC-A0322
RXRB NM_021976.5 Human Homo sapiens retinoid X receptor beta (RXRB), transcript variant 2, mRNA. 1602 GC-A0346
GNRHR NM_000406.3 Human Homo sapiens gonadotropin releasing hormone receptor (GNRHR), transcript variant 1, mRNA. 987 GC-A0455
AHR NM_001621.5 Human Homo sapiens aryl hydrocarbon receptor (AHR), mRNA. 2547 GC-A0474
GHR NM_001242401.4 Human Homo sapiens growth hormone receptor (GHR), transcript variant 4, mRNA. 1917 GC-A0521
RXRA NM_002957.6 Human Homo sapiens retinoid X receptor alpha (RXRA), transcript variant 1, mRNA. 1389 GC-A0529
NR0B1 NM_000475.5 Human Homo sapiens nuclear receptor subfamily 0 group B member 1 (NR0B1), mRNA. 1413 GC-A0573
CRHR2 NM_001883.5 Human Homo sapiens corticotropin releasing hormone receptor 2 (CRHR2), transcript variant 1, mRNA. 1236 GC-A0634
NR1D1 NM_021724.5 Human Homo sapiens nuclear receptor subfamily 1 group D member 1 (NR1D1), mRNA. 1845 GC-A0803
THRA NM_001190919.2 Human Homo sapiens thyroid hormone receptor alpha (THRA), transcript variant 4, mRNA. 1473 GC-A0835
NR3C1 NM_001024094.2 Human Homo sapiens nuclear receptor subfamily 3 group C member 1 (NR3C1), transcript variant 7, mRNA. 2337 GC-A0857
NR1I3 NM_005122.5 Human Homo sapiens nuclear receptor subfamily 1 group I member 3 (NR1I3), transcript variant 3, mRNA. 1047 GC-A0964
TRHR NM_003301.7 Human Homo sapiens thyrotropin releasing hormone receptor (TRHR), mRNA. 1197 GC-A0971
NR2F1 NM_005654.6 Human Homo sapiens nuclear receptor subfamily 2 group F member 1 (NR2F1), mRNA. 1272 GC-A1000
NR1H3 NM_005693.4 Human Homo sapiens nuclear receptor subfamily 1 group H member 3 (NR1H3), transcript variant 1, mRNA. 1344 GC-A1306
NR2F2 NM_021005.4 Human Homo sapiens nuclear receptor subfamily 2 group F member 2 (NR2F2), transcript variant 1, mRNA. 1245 GC-C0221
ESRRG NM_001438.4 Human Homo sapiens estrogen related receptor gamma (ESRRG), transcript variant 1, mRNA. 1377 GC-E0424
PPARD NM_006238.5 Human Homo sapiens peroxisome proliferator activated receptor delta (PPARD), transcript variant 1, mRNA. 1326 GC-G0246
RARA NM_001145301.3 Human Homo sapiens retinoic acid receptor alpha (RARA), transcript variant 3, mRNA. 1389 GC-H0048
NR4A2 NM_006186.4 Human Homo sapiens nuclear receptor subfamily 4 group A member 2 (NR4A2), transcript variant 1, mRNA. 1797 GC-I0539
NR1H2 NM_007121.5 Human Homo sapiens nuclear receptor subfamily 1 group H member 2 (NR1H2), transcript variant 1, mRNA. 1386 GC-M0003
NR4A3 NM_173199.4 Human Homo sapiens nuclear receptor subfamily 4 group A member 3 (NR4A3), transcript variant 4, mRNA. 1332 GC-M0934
NR1D2 NM_005126.5 Human Homo sapiens nuclear receptor subfamily 1 group D member 2 (NR1D2), transcript variant 1, mRNA. 1740 GC-P0004
NR5A1 NM_004959.5 Human Homo sapiens nuclear receptor subfamily 5 group A member 1 (NR5A1), mRNA. 1386 GC-P0006
NR6A1 NM_033334.4 Human Homo sapiens nuclear receptor subfamily 6 group A member 1 (NR6A1), transcript variant 1, mRNA. 1443 GC-P0009
NR2E3 NM_014249.4 Human Homo sapiens nuclear receptor subfamily 2 group E member 3 (NR2E3), transcript variant 2, mRNA. 1233 GC-P0012
RARB NM_001290217.2 Human Homo sapiens retinoic acid receptor beta (RARB), transcript variant 4, mRNA. 1011 GC-P0014
NR2E1 NM_003269.5 Human Homo sapiens nuclear receptor subfamily 2 group E member 1 (NR2E1), transcript variant 2, mRNA. 1158 GC-P0019
PPARG NM_015869.5 Human Homo sapiens peroxisome proliferator activated receptor gamma (PPARG), transcript variant 2, mRNA. 1518 GC-Q0148
NR5A2 NM_003822.5 Human Homo sapiens nuclear receptor subfamily 5 group A member 2 (NR5A2), transcript variant 2, mRNA. 1488 GC-Q0618
TRH NM_007117.5 Human Homo sapiens thyrotropin releasing hormone (TRH), mRNA. 729 GC-S0380
RORA NM_134260.2 Human Homo sapiens RAR related orphan receptor A (RORA), transcript variant 2, mRNA. 1671 GC-T0080
RARG NM_000966.6 Human Homo sapiens retinoic acid receptor gamma (RARG), transcript variant 1, mRNA. 1365 GC-T0175
NR1H4 NM_005123.4 Human Homo sapiens nuclear receptor subfamily 1 group H member 4 (NR1H4), transcript variant 2, mRNA. 1419 GC-T0601
NR0B2 NM_021969.3 Human Homo sapiens nuclear receptor subfamily 0 group B member 2 (NR0B2), mRNA. 774 GC-T1368
NR1I2 NM_022002.3 Human Homo sapiens nuclear receptor subfamily 1 group I member 2 (NR1I2), transcript variant 2, mRNA. 1422 GC-T2079
RORA NM_134261.2 Human Homo sapiens RAR related orphan receptor A (RORA), transcript variant 1, mRNA. 1572 GC-T3100
RORC NM_001001523.2 Human Homo sapiens RAR related orphan receptor C (RORC), transcript variant 2, mRNA. 1494 GC-T6988
PTGER3 NM_198716.2 Human Homo sapiens prostaglandin E receptor 3 (PTGER3), transcript variant 6, mRNA. 1125 GC-T7970
THRB NM_001252634.2 Human Homo sapiens thyroid hormone receptor beta (THRB), transcript variant 4, mRNA. 1386 GC-T9450
ESR2 NM_001437.3 Human Homo sapiens estrogen receptor 2 (ESR2), transcript variant a, mRNA. 1593 GC-U0033
GHSR NM_004122.2 Human Homo sapiens growth hormone secretagogue receptor (GHSR), transcript variant 1b, mRNA. 870 GC-U0190
NR2E3 NM_016346.4 Human Homo sapiens nuclear receptor subfamily 2 group E member 3 (NR2E3), transcript variant 1, mRNA. 1104 GC-X0397
GHSR NM_198407.2 Human Homo sapiens growth hormone secretagogue receptor (GHSR), transcript variant 1a, mRNA. 1101 GC-X0963
PTGER3 NM_198719.2 Human Homo sapiens prostaglandin E receptor 3 (PTGER3), transcript variant 9, mRNA. 1173 GC-Y0003
PTGER3 NM_198715.3 Human Homo sapiens prostaglandin E receptor 3 (PTGER3), transcript variant 5, mRNA. 1167 GC-Y0004
PTGER3 NM_198717.2 Human Homo sapiens prostaglandin E receptor 3 (PTGER3), transcript variant 7, mRNA. 1098 GC-Y0005
NR1H3 NM_001130101.3 Human Homo sapiens nuclear receptor subfamily 1 group H member 3 (NR1H3), transcript variant 2, mRNA. 1164 GC-Z0276