All human and mice ORF clones and related Lentivirus, AAV particles and recombinant proteins provided by GeneCopoeia are fully sequenced using Sanger sequencing by capillary electrophoresis and Amino Acid Sequences are guaranteed to be matched with NCBI database.

Drug target genes

Introduction

Drug targets are biomacromolecule in the body that have pharmacodynamic functions by interacting with drugs, such as certain proteins and nucleic acids. The genes that encode target proteins are also known as target genes. The identification of target molecules related to specific diseases in advance is the basis for modern drug development. For example, CTLA4, a classical T-cell immune checkpoint in tumor immunotherapy, is a transmembrane protein encoded by the CTLA-4 gene, which is expressed in activated CD4+ and CD8+ T cells, as well as Lymphocyte Activation Gene 3 (LAG-3) and T-cell Immunoglobulin Mucin 3 (TIM-3).

Clone set information

Cat. no.	Species	Gene	Vector	Vector Type	Price
OC-HDG-M02	Human	8611	pReceiver-M02	Expression-ready Non-viral	Inquire
OC-HDG-M35	Human	8611	pReceiver-M35	Expression-ready Non-viral	Inquire
OC-HDG-M98	Human	8611	pReceiver-M98	Expression-ready Non-viral	Inquire
OC-HDG-Lv105	Human	8611	pReceiver-Lv105	Expression-ready Lentiviral	Inquire
OC-HDG-Lv242	Human	8611	pReceiver-Lv242	Expression-ready Lentiviral	Inquire
OC-HDG-GC	Human	8611	pDONR™ Vector	Gateway shuttle	Inquire

Clone list

The form only shows 50 clones of the whole set. Please contact us at 1-301-762-0888 or inquiry@genecopoeia.com if you have any questions.

Symbol	Accession	Species	Description	ORF length(bp)	Product ID
IFNA1	NM_024013.3	Human	Homo sapiens interferon alpha 1 (IFNA1), mRNA.	570	GC-A0001
PTN	NM_002825.7	Human	Homo sapiens pleiotrophin (PTN), transcript variant 1, mRNA.	507	GC-A0004
IL10	NM_000572.3	Human	Homo sapiens interleukin 10 (IL10), transcript variant 1, mRNA.	537	GC-A0007
ITGA3	NM_002204.4	Human	Homo sapiens integrin subunit alpha 3 (ITGA3), mRNA.	3156	GC-A0010
KITLG	NM_000899.5	Human	Homo sapiens KIT ligand (KITLG), transcript variant b, mRNA.	822	GC-A0012
HBEGF	NM_001945.3	Human	Homo sapiens heparin binding EGF like growth factor (HBEGF), mRNA.	627	GC-A0014
BMP5	NM_021073.4	Human	Homo sapiens bone morphogenetic protein 5 (BMP5), transcript variant 1, mRNA.	1365	GC-A0015
BMP6	NM_001718.6	Human	Homo sapiens bone morphogenetic protein 6 (BMP6), mRNA.	1542	GC-A0016
FGF7	NM_002009.4	Human	Homo sapiens fibroblast growth factor 7 (FGF7), mRNA.	585	GC-A0017
AKT1	NM_005163.2	Human	Homo sapiens AKT serine/threonine kinase 1 (AKT1), transcript variant 1, mRNA.	1443	GC-A0022
PTPN3	NM_002829.4	Human	Homo sapiens protein tyrosine phosphatase non-receptor type 3 (PTPN3), transcript variant 1, mRNA.	2742	GC-A0027
IL12B	NM_002187.3	Human	Homo sapiens interleukin 12B (IL12B), mRNA.	987	GC-A0033
IL12A	NM_000882.4	Human	Homo sapiens interleukin 12A (IL12A), transcript variant 1, mRNA.	762	GC-A0034
CDK2	NM_001798.5	Human	Homo sapiens cyclin dependent kinase 2 (CDK2), transcript variant 1, mRNA.	897	GC-A0035
MAOB	NM_000898.5	Human	Homo sapiens monoamine oxidase B (MAOB), mRNA.	1563	GC-A0038
CNTFR	NM_001842.5	Human	Homo sapiens ciliary neurotrophic factor receptor (CNTFR), transcript variant 2, mRNA.	1119	GC-A0039
ITGB8	NM_002214.3	Human	Homo sapiens integrin subunit beta 8 (ITGB8), mRNA.	2310	GC-A0040
TACR1	NM_001058.4	Human	Homo sapiens tachykinin receptor 1 (TACR1), transcript variant long, mRNA.	1224	GC-A0041
IL3RA	NM_002183.4	Human	Homo sapiens interleukin 3 receptor subunit alpha (IL3RA), transcript variant 1, mRNA.	1137	GC-A0042
VDR	NM_001017535.2	Human	Homo sapiens vitamin D receptor (VDR), transcript variant 2, mRNA.	1284	GC-A0043
ADCY8	NM_001115.3	Human	Homo sapiens adenylate cyclase 8 (ADCY8), mRNA.	3756	GC-A0054
CHRNA5	NM_000745.4	Human	Homo sapiens cholinergic receptor nicotinic alpha 5 subunit (CHRNA5), transcript variant 1, mRNA.	1407	GC-A0055
EPHA3	NM_005233.6	Human	Homo sapiens EPH receptor A3 (EPHA3), transcript variant 1, mRNA.	2952	GC-A0059
FPR2	NM_001462.3	Human	Homo sapiens formyl peptide receptor 2 (FPR2), transcript variant 1, mRNA.	1056	GC-A0060
TGFBR2	NM_003242.6	Human	Homo sapiens transforming growth factor beta receptor 2 (TGFBR2), transcript variant 2, mRNA.	1704	GC-A0063
IGFALS	NM_004970.3	Human	Homo sapiens insulin like growth factor binding protein acid labile subunit (IGFALS), transcript variant 2, mRNA.	1818	GC-A0066
TACR3	NM_001059.3	Human	Homo sapiens tachykinin receptor 3 (TACR3), mRNA.	1398	GC-A0068
AGER	NM_001136.4	Human	Homo sapiens advanced glycosylation end-product specific receptor (AGER), transcript variant 1, mRNA.	1215	GC-A0070
ACVR2A	NM_001616.5	Human	Homo sapiens activin A receptor type 2A (ACVR2A), transcript variant 2, mRNA.	1542	GC-A0075
CXCR2	NM_001557.4	Human	Homo sapiens C-X-C motif chemokine receptor 2 (CXCR2), transcript variant 1, mRNA.	1083	GC-A0079
SLC6A3	NM_001044.5	Human	Homo sapiens solute carrier family 6 member 3 (SLC6A3), mRNA.	1863	GC-A0080
ADORA2B	NM_000676.4	Human	Homo sapiens adenosine A2b receptor (ADORA2B), mRNA.	999	GC-A0085
BRS3	NM_001727.2	Human	Homo sapiens bombesin receptor subtype 3 (BRS3), mRNA.	1200	GC-A0093
ANG	NM_001145.4	Human	Homo sapiens angiogenin (ANG), transcript variant 1, mRNA.	444	GC-A0098
MAS1	NM_002377.4	Human	Homo sapiens MAS1 proto-oncogene, G protein-coupled receptor (MAS1), transcript variant 1, mRNA.	978	GC-A0099
NGFR	NM_002507.4	Human	Homo sapiens nerve growth factor receptor (NGFR), mRNA.	1284	GC-A0100
BCHE	NM_000055.4	Human	Homo sapiens butyrylcholinesterase (BCHE), transcript variant 1, mRNA.	1809	GC-A0103
ICAM1	NM_000201.3	Human	Homo sapiens intercellular adhesion molecule 1 (ICAM1), mRNA.	1599	GC-A0111
PTMS	NM_002824.6	Human	Homo sapiens parathymosin (PTMS), transcript variant 2, mRNA.	309	GC-A0112
AREG	NM_001657.4	Human	Homo sapiens amphiregulin (AREG), mRNA.	759	GC-A0114
PTPN1	NM_002827.4	Human	Homo sapiens protein tyrosine phosphatase non-receptor type 1 (PTPN1), transcript variant 1, mRNA.	1308	GC-A0118
ACHE	NM_000665.5	Human	Homo sapiens acetylcholinesterase (Cartwright blood group) (ACHE), transcript variant E4-E6, mRNA.	1845	GC-A0120
KCNA5	NM_002234.4	Human	Homo sapiens potassium voltage-gated channel subfamily A member 5 (KCNA5), mRNA.	1842	GC-A0121
EPHA2	NM_004431.5	Human	Homo sapiens EPH receptor A2 (EPHA2), transcript variant 1, mRNA.	2931	GC-A0125
PTPN4	NM_002830.4	Human	Homo sapiens protein tyrosine phosphatase non-receptor type 4 (PTPN4), mRNA.	2781	GC-A0131
GRPR	NM_005314.3	Human	Homo sapiens gastrin releasing peptide receptor (GRPR), mRNA.	1155	GC-A0132
IFNB1	NM_002176.4	Human	Homo sapiens interferon beta 1 (IFNB1), mRNA.	564	GC-A0137
GABRA1	NM_001127643.2	Human	Homo sapiens gamma-aminobutyric acid type A receptor subunit alpha1 (GABRA1), transcript variant 2, mRNA.	1371	GC-A0140
IL4R	NM_000418.4	Human	Homo sapiens interleukin 4 receptor (IL4R), transcript variant 1, mRNA.	2478	GC-A0144
PTPRE	NM_001316677.2	Human	Homo sapiens protein tyrosine phosphatase receptor type E (PTPRE), transcript variant 4, mRNA.	2103	GC-A0148