All human and mice ORF clones and related Lentivirus, AAV particles and recombinant proteins provided by GeneCopoeia are fully sequenced using Sanger sequencing by capillary electrophoresis and Amino Acid Sequences are guaranteed to be matched with NCBI database.

Kinases

Introduction

Kinases are enzymes that catalyze the transfer of phosphate groups from high-energy phosphorus-containing molecules (e.g., ATP) to a substrate, and the largest kinase group is protein kinases. Kinases exert their effects by phosphorylating their respective downstream specific substrate proteins. They catalyze the transfer of γ-phosphate from ATP or GTP to the hydroxyl groups of serine, threonine, and tyrosine in substrate proteins or the glycosyl portion of lipids.

Kinases include: adenylate kinase (AMPK), creatine kinase (CK), pyruvate kinase (PK), hexokinase (HK), nucleoside diphosphate kinases (NDPKs), and thymidine kinases (TK1/TK2). Kinase dysregulation can lead to changes in enzyme activity and/or enzyme expression, subcellular localization, kinase stability, protein-protein interactions, etc. Aberrant regulation of kinase-mediated signaling pathways is responsible for all major human pathological conditions such as cancer, cardiovascular diseases, neurodegenerative diseases and metabolic disorders.

Clone set information

Cat. No.	Old Cat. No.	Species	Gene	Vector	Vector Type	Price
OC-GF013-M02	OC-HKI-M02	Human	666	pReceiver-M02	Expression-ready Non-viral	Inquire
OC-GF013-M35	OC-HKI-M35	Human	666	pReceiver-M35	Expression-ready Non-viral	Inquire
OC-GF013-M98	OC-HKI-M98	Human	666	pReceiver-M98	Expression-ready Non-viral	Inquire
OC-GF013-Lv105	OC-HKI-Lv105	Human	666	pReceiver-Lv105	Expression-ready Lentiviral	Inquire
OC-GF013-Lv242	OC-HKI-Lv242	Human	666	pReceiver-Lv242	Expression-ready Lentiviral	Inquire
OC-GF013-GC	OC-HKI-GC	Human	666	pDONR™ Vector	Gateway shuttle	Inquire

Clone list

The form only shows 50 clones of the whole set. Please contact us at 1-301-762-0888 or inquiry@genecopoeia.com if you have any questions.

Symbol	Accession	Species	Description	ORF length(bp)	Product ID
CAMK4	NM_001744.4	Human	Homo sapiens calcium/calmodulin-dependent protein kinase IV (CAMK4), mRNA.	1422	GC-A0231
NEK4	NM_003157.6	Human	Homo sapiens NIMA related kinase 4 (NEK4), transcript variant 1, mRNA.	2526	GC-Z8322
AKT1	NM_001014431.2	Human	Homo sapiens AKT serine/threonine kinase 1 (AKT1), transcript variant 3, mRNA.	1443	GC-Z5980
TFG	NM_001007565.2	Human	Homo sapiens trafficking from ER to golgi regulator (TFG), transcript variant 2, mRNA.	1203	GC-Z5959
FGFRL1	NM_001004356.3	Human	Homo sapiens fibroblast growth factor receptor like 1 (FGFRL1), transcript variant 1, mRNA.	1515	GC-Z5940
PASK	NM_015148.4	Human	Homo sapiens PAS domain containing serine/threonine kinase (PASK), transcript variant 2, mRNA.	3972	GC-E3214
ACVRL1	NM_000020.3	Human	Homo sapiens activin A receptor like type 1 (ACVRL1), transcript variant 1, mRNA.	1512	GC-M0844
BTK	NM_000061.3	Human	Homo sapiens Bruton tyrosine kinase (BTK), transcript variant 1, mRNA.	1980	GC-A0534
CDK4	NM_000075.4	Human	Homo sapiens cyclin dependent kinase 4 (CDK4), mRNA.	912	GC-T1758
ENG	NM_000118.4	Human	Homo sapiens endoglin (ENG), transcript variant 2, mRNA.	1878	GC-Y2005
ERCC3	NM_000122.2	Human	Homo sapiens ERCC excision repair 3, TFIIH core complex helicase subunit (ERCC3), transcript variant 1, mRNA.	2349	GC-Q0554
FGFR2	NM_000141.5	Human	Homo sapiens fibroblast growth factor receptor 2 (FGFR2), transcript variant 1, mRNA.	2466	GC-A0979
FGFR3	NM_000142.4	Human	Homo sapiens fibroblast growth factor receptor 3 (FGFR3), transcript variant 1, mRNA.	2421	GC-M0098
GUCY2D	NM_000180.4	Human	Homo sapiens guanylate cyclase 2D, retinal (GUCY2D), mRNA.	3312	GC-Z0715
INSR	NM_000208.4	Human	Homo sapiens insulin receptor (INSR), transcript variant 1, mRNA.	4149	GC-Y4566
JAK3	NM_000215.4	Human	Homo sapiens Janus kinase 3 (JAK3), mRNA.	3375	GC-Z2520
KIT	NM_000222.3	Human	Homo sapiens KIT proto-oncogene, receptor tyrosine kinase (KIT), transcript variant 1, mRNA.	2931	GC-A0519
KCNH2	NM_000238.4	Human	Homo sapiens potassium voltage-gated channel subfamily H member 2 (KCNH2), transcript variant 1, mRNA.	3480	GC-A1128
MET	NM_000245.4	Human	Homo sapiens MET proto-oncogene, receptor tyrosine kinase (MET), transcript variant 2, mRNA.	4173	GC-H0648
PHKA2	NM_000292.3	Human	Homo sapiens phosphorylase kinase regulatory subunit alpha 2 (PHKA2), mRNA.	3708	GC-T0189
PHKG2	NM_000294.3	Human	Homo sapiens phosphorylase kinase catalytic subunit gamma 2 (PHKG2), transcript variant 1, mRNA.	1221	GC-C0071
ERCC2	NM_000400.4	Human	Homo sapiens ERCC excision repair 2, TFIIH core complex helicase subunit (ERCC2), transcript variant 1, mRNA.	2283	GC-T3631
STK11	NM_000455.5	Human	Homo sapiens serine/threonine kinase 11 (STK11), mRNA.	1302	GC-T0511
FKBP1A	NM_000801.5	Human	Homo sapiens FKBP prolyl isomerase 1A (FKBP1A), transcript variant 1, mRNA.	327	GC-R0062
IGF1R	NM_000875.5	Human	Homo sapiens insulin like growth factor 1 receptor (IGF1R), transcript variant 1, mRNA.	4104	GC-L0202
MAP3K15	NM_001001671.4	Human	Homo sapiens mitogen-activated protein kinase kinase kinase 15 (MAP3K15), mRNA.	3942	GC-H5310
PIM3	NM_001001852.4	Human	Homo sapiens Pim-3 proto-oncogene, serine/threonine kinase (PIM3), mRNA.	981	GC-Y5231
EXOSC10	NM_001001998.3	Human	Homo sapiens exosome component 10 (EXOSC10), transcript variant 1, mRNA.	2658	GC-G0202
STRADA	NM_001003787.4	Human	Homo sapiens STE20 related adaptor alpha (STRADA), transcript variant 1, mRNA.	1296	GC-W1052
STRADA	NM_001003788.3	Human	Homo sapiens STE20 related adaptor alpha (STRADA), transcript variant 4, mRNA.	1122	GC-E2267
GRK6	NM_001004106.3	Human	Homo sapiens G protein-coupled receptor kinase 6 (GRK6), transcript variant 1, mRNA.	1731	GC-A0473
FGFRL1	NM_001004358.1	Human	Homo sapiens fibroblast growth factor receptor-like 1 (FGFRL1), transcript variant 2, mRNA.	1515	GC-U1357
RYK	NM_001005861.3	Human	Homo sapiens receptor like tyrosine kinase (RYK), transcript variant 1, mRNA.	1833	GC-Z4052
ERBB2	NM_001005862.3	Human	Homo sapiens erb-b2 receptor tyrosine kinase 2 (ERBB2), transcript variant 2, mRNA.	3678	GC-Z2767
ERBB3	NM_001005915.1	Human	Homo sapiens erb-b2 receptor tyrosine kinase 3 (ERBB3), transcript variant s, mRNA.	552	GC-Y2798
MAPKAP1	NM_001006617.3	Human	Homo sapiens MAPK associated protein 1 (MAPKAP1), transcript variant 1, mRNA.	1569	GC-Z4054
MAPKAP1	NM_001006620.2	Human	Homo sapiens MAPK associated protein 1 (MAPKAP1), transcript variant 4, mRNA.	993	GC-Z3530
RPS6KA1	NM_001006665.1	Human	Homo sapiens ribosomal protein S6 kinase A1 (RPS6KA1), transcript variant 2, mRNA.	2235	GC-Z4056
EPHA8	NM_001006943.3	Human	Homo sapiens EPH receptor A8 (EPHA8), transcript variant 2, mRNA.	1488	GC-T8397
NTRK2	NM_001007097.3	Human	Homo sapiens neurotrophic receptor tyrosine kinase 2 (NTRK2), transcript variant b, mRNA.	1434	GC-A1072
NTRK3	NM_001007156.2	Human	Homo sapiens neurotrophic receptor tyrosine kinase 3 (NTRK3), transcript variant 3, mRNA.	1839	GC-Z5958
NTRK1	NM_001007792.1	Human	Homo sapiens neurotrophic receptor tyrosine kinase 1 (NTRK1), transcript variant 3, mRNA.	2283	GC-Z4075
IRAK1BP1	NM_001010844.4	Human	Homo sapiens interleukin 1 receptor associated kinase 1 binding protein 1 (IRAK1BP1), mRNA.	783	GC-Y3609
NTRK1	NM_001012331.2	Human	Homo sapiens neurotrophic receptor tyrosine kinase 1 (NTRK1), transcript variant 1, mRNA.	2373	GC-Z5973
NTRK3	NM_001012338.2	Human	Homo sapiens neurotrophic receptor tyrosine kinase 3 (NTRK3), transcript variant 1, mRNA.	2520	GC-Z5974
MYLK4	NM_001012418.5	Human	Homo sapiens myosin light chain kinase family member 4 (MYLK4), transcript variant 1, mRNA.	1167	GC-Y2836
EIF2AK4	NM_001013703.4	Human	Homo sapiens eukaryotic translation initiation factor 2 alpha kinase 4 (EIF2AK4), mRNA.	4950	GC-A8526
PAK4	NM_001014831.3	Human	Homo sapiens p21 (RAC1) activated kinase 4 (PAK4), transcript variant 2, mRNA.	1776	GC-Z0120
PAK4	NM_001014835.2	Human	Homo sapiens p21 (RAC1) activated kinase 4 (PAK4), transcript variant 4, mRNA.	1317	GC-Z4122
AURKC	NM_001015878.2	Human	Homo sapiens aurora kinase C (AURKC), transcript variant 1, mRNA.	930	GC-Q0034