All human and mice ORF clones and related Lentivirus, AAV particles and recombinant proteins provided by GeneCopoeia are fully sequenced using Sanger sequencing by capillary electrophoresis and Amino Acid Sequences are guaranteed to be matched with NCBI database.

Protease inhibitors

Introduction

Protease inhibitors are molecules that inhibit the function of proteases, and many naturally occurring protease inhibitors are proteins. Protease inhibitors can be used as antiviral drugs and the FDA has approved the marketing of 7 protease inhibitor drugs including SQV, RTV, IDV, NFV, and APV, etc.

Protease inhibitors are further categorized into serine protease inhibitors, cysteine protease inhibitors, aspartate protease inhibitors, and metalloproteinase inhibitors based on homology of amino acid sequences and target proteases. Mutations in the key amino acids of proteases and their inhibitors can affect their physiological functions, stability, catalytic activity, inhibitory specificity, and so on.

It has become one of the current hotspots to explore various mutants of proteases and their inhibitors in nature, analyze their key active sites, and use protein engineering to modify and design proteases and their inhibitors with stronger activity, higher stability, better specificity, more environmentally friendly, and lower cost.

Clone set information

Cat. No.	Old Cat. No.	Species	Gene	Vector	Vector Type	Price
OC-GF017-M02	OC-HPI-M02	Human	154	pReceiver-M02	Expression-ready Non-viral	Inquire
OC-GF017-M35	OC-HPI-M35	Human	154	pReceiver-M35	Expression-ready Non-viral	Inquire
OC-GF017-M98	OC-HPI-M98	Human	154	pReceiver-M98	Expression-ready Non-viral	Inquire
OC-GF017-Lv105	OC-HPI-Lv105	Human	154	pReceiver-Lv105	Expression-ready Lentiviral	Inquire
OC-GF017-Lv242	OC-HPI-Lv242	Human	154	pReceiver-Lv242	Expression-ready Lentiviral	Inquire
OC-GF017-GC	OC-HPI-GC	Human	154	pDONR™ Vector	Gateway shuttle	Inquire

Clone list

The form only shows 50 clones of the whole set. Please contact us at 1-301-762-0888 or inquiry@genecopoeia.com if you have any questions.

Symbol	Accession	Species	Description	ORF length(bp)	Product ID
CD109	NM_133493.5	Human	Homo sapiens CD109 molecule (CD109), transcript variant 1, mRNA.	4338	GC-E1159
SPINT1	NM_003710.4	Human	Homo sapiens serine peptidase inhibitor, Kunitz type 1 (SPINT1), transcript variant 2, mRNA.	1542	GC-M0314
XIAP	NM_001204401.2	Human	Homo sapiens X-linked inhibitor of apoptosis (XIAP), transcript variant 2, mRNA.	1494	GC-T0104
KAZALD1	NM_030929.5	Human	Homo sapiens Kazal type serine peptidase inhibitor domain 1 (KAZALD1), transcript variant 1, mRNA.	915	GC-V1110
WFDC5	NM_145652.4	Human	Homo sapiens WAP four-disulfide core domain 5 (WFDC5), transcript variant 1, mRNA.	372	GC-Y2198
SERPINE1	NM_000602.5	Human	Homo sapiens serpin family E member 1 (SERPINE1), transcript variant 2, mRNA.	1209	GC-F0606
WFDC2	NM_006103.4	Human	Homo sapiens WAP four-disulfide core domain 2 (WFDC2), mRNA.	375	GC-Z1019
SPINT1	NM_181642.3	Human	Homo sapiens serine peptidase inhibitor, Kunitz type 1 (SPINT1), transcript variant 1, mRNA.	1590	GC-Z5300
C3	NM_000064.4	Human	Homo sapiens complement C3 (C3), mRNA.	4992	GC-E2587
CD109	NM_001159587.3	Human	Homo sapiens CD109 molecule (CD109), transcript variant 2, mRNA.	4287	GC-E2721
CD109	NM_001159588.3	Human	Homo sapiens CD109 molecule (CD109), transcript variant 3, mRNA.	4107	GC-E2722
XIAP	NM_001167.4	Human	Homo sapiens X-linked inhibitor of apoptosis (XIAP), transcript variant 1, mRNA.	1494	GC-H4489
SERPINB2	NM_001143818.2	Human	Homo sapiens serpin family B member 2 (SERPINB2), transcript variant 1, mRNA.	1248	GC-Z6805
AMBP	NM_001633.4	Human	Homo sapiens alpha-1-microglobulin/bikunin precursor (AMBP), mRNA.	1059	GC-G0166
APLP2	NM_001642.3	Human	Homo sapiens amyloid beta precursor like protein 2 (APLP2), transcript variant 1, mRNA.	2292	GC-Y2612
APLP2	NM_001142278.2	Human	Homo sapiens amyloid beta precursor like protein 2 (APLP2), transcript variant 4, mRNA.	1569	GC-Y4654
APP	NM_201414.3	Human	Homo sapiens amyloid beta precursor protein (APP), transcript variant 3, mRNA.	2088	GC-F0776
APP	NM_000484.4	Human	Homo sapiens amyloid beta precursor protein (APP), transcript variant 1, mRNA.	2313	GC-Z2553
APP	NM_201413.3	Human	Homo sapiens amyloid beta precursor protein (APP), transcript variant 2, mRNA.	2256	GC-Z3473
APP	NM_001136130.3	Human	Homo sapiens amyloid beta precursor protein (APP), transcript variant 6, mRNA.	2145	GC-Z6628
BCL2L1	NM_001317921.2	Human	Homo sapiens BCL2 like 1 (BCL2L1), transcript variant 5, mRNA.	702	GC-B0212
BCL2L1	NM_001191.4	Human	Homo sapiens BCL2 like 1 (BCL2L1), transcript variant 2, mRNA.	513	GC-Z2522
BIRC5	NM_001012270.2	Human	Homo sapiens baculoviral IAP repeat containing 5 (BIRC5), transcript variant 2, mRNA.	414	GC-Z3551
C4B	NM_001002029.4	Human	Homo sapiens complement C4B (Chido blood group) (C4B), mRNA.	5235	GC-E2592
CAST	NM_001042444.3	Human	Homo sapiens calpastatin (CAST), transcript variant 10, mRNA.	2004	GC-T9667
CRIM1	NM_016441.3	Human	Homo sapiens cysteine rich transmembrane BMP regulator 1 (CRIM1), mRNA.	3111	GC-U1217
CST11	NM_130794.2	Human	Homo sapiens cystatin 11 (CST11), transcript variant 1, mRNA.	417	GC-T3222
CST11	NM_080830.3	Human	Homo sapiens cystatin 11 (CST11), transcript variant 2, mRNA.	312	GC-H0931
CST2	NM_001322.3	Human	Homo sapiens cystatin SA (CST2), mRNA.	426	GC-Z2898
CST3	NM_001288614.1	Human	Homo sapiens cystatin C (CST3), transcript variant 2, mRNA.	441	GC-F0113
CST4	NM_001899.3	Human	Homo sapiens cystatin S (CST4), mRNA.	426	GC-F0420
CST6	NM_001323.4	Human	Homo sapiens cystatin E/M (CST6), mRNA.	450	GC-M0688
CST7	NM_003650.4	Human	Homo sapiens cystatin F (CST7), mRNA.	438	GC-U0145
CST8	NM_001281730.2	Human	Homo sapiens cystatin 8 (CST8), transcript variant 2, mRNA.	429	GC-W0217
CST9	NM_001008693.3	Human	Homo sapiens cystatin 9 (CST9), mRNA.	480	GC-H3350
CST9L	NM_080610.3	Human	Homo sapiens cystatin 9 like (CST9L), mRNA.	444	GC-T3229
CSTA	NM_005213.4	Human	Homo sapiens cystatin A (CSTA), mRNA.	297	GC-F0405
CSTB	NM_000100.4	Human	Homo sapiens cystatin B (CSTB), mRNA.	297	GC-F0136
CSTL1	NM_138283.1	Human	Homo sapiens cystatin like 1 (CSTL1), mRNA.	438	GC-T3228
FETUB	NM_014375.3	Human	Homo sapiens fetuin B (FETUB), transcript variant 1, mRNA.	1149	GC-I0029
GPC3	NM_004484.4	Human	Homo sapiens glypican 3 (GPC3), transcript variant 2, mRNA.	1743	GC-I0391
GPC3	NM_001164617.2	Human	Homo sapiens glypican 3 (GPC3), transcript variant 1, mRNA.	1812	GC-Z7351
GPC3	NM_001164618.2	Human	Homo sapiens glypican 3 (GPC3), transcript variant 3, mRNA.	1695	GC-Z7352
GPC3	NM_001164619.2	Human	Homo sapiens glypican 3 (GPC3), transcript variant 4, mRNA.	1581	GC-Z7353
GPX1	NM_000581.4	Human	Homo sapiens glutathione peroxidase 1 (GPX1), transcript variant 1, mRNA.	612	GC-Z2571
GPX1	NM_201397.3	Human	Homo sapiens glutathione peroxidase 1 (GPX1), transcript variant 2, mRNA.	297	GC-Z3958
HMSD	NM_001123366.2	Human	Homo sapiens histocompatibility minor serpin domain containing (HMSD), mRNA.	420	GC-H3031
HRG	NM_000412.5	Human	Homo sapiens histidine rich glycoprotein (HRG), mRNA.	1578	GC-G0140
HSPA5	NM_005347.5	Human	Homo sapiens heat shock protein family A (Hsp70) member 5 (HSPA5), mRNA.	1965	GC-T3592
ITIH2	NM_002216.3	Human	Homo sapiens inter-alpha-trypsin inhibitor heavy chain 2 (ITIH2), mRNA.	2841	GC-Z5660