Answer: The full-length ORF clones contain only the protein coding sequences, while other full-length whole transcript cDNA clones contain non-coding sequences, such as 5' and/or 3' UTRs, which have been known to have possible negative impact on the protein translation process. Please visit this page for further details on the comparison of these two types of clones: (https://www.genecopoeia.com/tech/application/).