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shRNA clone targeting E3 ubiquitin ligases

Introduction E3 ubiquitin ligases are key components of the ubiquitin–proteasome system (UPS), selecting and tagging target proteins for degradation or regulation. They are responsible for selecting and labelling target proteins for degradation or regulation. The UPS...
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E3 ubiquitin ligases

Introduction E3 ubiquitin ligases are key components of the ubiquitin–proteasome system, selecting and tagging target proteins for degradation or regulation. With over 600 members, they control vital processes such as cell cycle, DNA repair, and immune signaling....
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E3 ubiquitin ligases

Introduction E3 ubiquitin ligases are key components of the ubiquitin–proteasome system (UPS), selecting and tagging target proteins for degradation or regulation. They are responsible for selecting and labelling target proteins for degradation or regulation. The UPS...
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Immune Checkpoint

Introduction Immune checkpoints are regulators of the immune system. The recognition of the antigenic peptide-MHC I/II complex on antigen presenting cells (APCs) through the T cell receptor (TCR) initiates T cell–mediated immunity. However, additional co-stimulatory...
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sgRNA targeting E3 ubiquitin ligases

Introduction E3 ubiquitin ligases are key components of the ubiquitin–proteasome system (UPS), selecting and tagging target proteins for degradation or regulation. They are responsible for selecting...

shRNA clone targeting E3 ubiquitin ligases

Introduction E3 ubiquitin ligases are key components of the ubiquitin–proteasome system (UPS), selecting and tagging target proteins for degradation or regulation. They are responsible for selecting...

E3 ubiquitin ligases

Introduction E3 ubiquitin ligases are key components of the ubiquitin–proteasome system, selecting and tagging target proteins for degradation or regulation. With over 600 members, they control...

Kinases

Introduction Kinases are enzymes that catalyze the transfer of phosphate groups from high-energy phosphorus-containing...

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Histones

Introduction Histones are alkaline proteins found in the chromatin of eukaryotic and prokaryotic cells, which form the...

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GPCRs

Introduction G protein-coupled receptors (GPCRs) are a large family of membrane protein receptors found only in...

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Epigenetics

Introduction Epigenetics is the study of heritable changes in gene function that do not involve alterations to the DNA...

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CDs

Introduction Cluster of differentiation (CD) antigens are cell surface molecules expressed on leukocytes and other...

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Reagents

GeneCopoeia, Inc. a U.S.-based functional genomics company founded in 1999, develops cutting edge products and...

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