Genome editing tools

sgRNA for CRISPR interference

Repress gene expression, without cutting the DNA CRISPR interference (CRISPRi) offers significant advantages over traditional gene knockdown methods like RNAi, including highly specific, reversible silencing of genes at the DNA level without altering the genome...
read more

sgRNA for CRISPR activation

Activate the transcription of any endogenous gene of interest, without cutting the DNA CRISPR Activation (CRISPRa) is a powerful, precise gene-editing tool that upregulates specific endogenous genes without cutting the DNA. Key advantages include high specificity with...
read more

sgRNA for CRISPRa and CRISPRi

CRISPR activation (CRISPRa) and interference (CRISPRi) are advanced genetic tools that utilize a catalytically "dead" Cas9 (dCas9) fused to effector proteins to modulate gene expression without cutting or altering the underlying DNA sequence. These technologies offer...
read more

GeneHero™ Cas9 Nuclease

[tab:Product Introduction] Recombinant Streptococcus pyogenes Cas9 nuclease, purified from E. coli, is a great choice for genome editing applications in vitro or in vivo. Available in two...
read more

sgRNA for CRISPR activation

Activate the transcription of any endogenous gene of interest, without cutting the DNA CRISPR Activation (CRISPRa) is a powerful, precise gene-editing tool that upregulates specific endogenous genes...

sgRNA for CRISPRa and CRISPRi

CRISPR activation (CRISPRa) and interference (CRISPRi) are advanced genetic tools that utilize a catalytically "dead" Cas9 (dCas9) fused to effector proteins to modulate gene expression without...