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Ion channels

Introduction Ion channels are transmembrane proteins with special functions on cell membranes (including cytoplasmic and intracellular membranes). Since charged ions cannot freely pass through the lipid bilayer, they can only be transported through ion channels. Ion...

Histone modification enzymes

Introduction Histone modification refers to the dynamic process by which histones are modified through methylation, acetylation, phosphorylation, adenylation, ubiquitination, ADP-ribosylation and other processes that are facilitated by specific enzymes. Histone...

Histones

Introduction Histones are alkaline proteins found in the chromatin of eukaryotic and prokaryotic cells, which form the structure of nucleosomes and are water-soluble together with DNA. They are mainly divided into five categories depending on their amino acid...

GPCRs

Introduction G protein-coupled receptors (GPCRs) are a large family of membrane protein receptors found only in eukaryotes. They are widely distributed in organs and tissues such as the central nervous system, immune system, cardiovascular system, and retina. GPCRs...

Chemokines and chemokine receptors

Introduction Cancer is a collection of diseases characterized by abnormal and uncontrolled cellular growth caused primarily by genetic mutations. Based on their role in cancer progression, driver...

Cancer driver gene

Introduction Cancer is a collection of diseases characterized by abnormal and uncontrolled cellular growth caused primarily by genetic mutations. Based on their role in cancer progression, driver...

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