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Drug target genes

Introduction Drug targets are biomacromolecules in the body that have pharmacodynamic functions by interacting with drugs, such as certain proteins and nucleic acids. The genes that encode target proteins are also known as target genes. The identification of target...

SARS-CoV-2 host interaction genes

Introduction SARS-CoV-2 is a strain of coronavirus that causes COVID-19. Studies have shown that more than 1,000 human proteins from different pathways are interaction partners of SARS-CoV-2. By interacting with host cell proteins, SARS-CoV-2 disrupts normal cellular...

CDs

Introduction Cluster of differentiation (CD) antigens are cell surface molecules expressed on leukocytes and other cells associated with the immune system. Physiologically, CDs can act in a variety of ways, often acting as important receptors or ligands for cells that...

Cytokines and cytokine receptors

Introduction Cytokines (CK) are low molecular weight soluble proteins (5-20 kDa) induced in a variety of cells by immunogens, mitogens, or other stimuli, generally through binding to the corresponding cytokine receptor on the cell surface, and through signaling,...

Immuno-oncology

Introduction Immuno-oncology is a scientific field that studies the interactions between tumors and the immune system, revealing how tumors evade immune surveillance and elimination, as well as how...

Transcription factors

Introduction Transcription factors, also known as trans-acting factors, are proteins that can bind to specific nucleotide sequences upstream of a gene, and these proteins can regulate the...

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