All human and mice ORF clones and related Lentivirus, AAV particles and recombinant proteins provided by GeneCopoeia are fully sequenced using Sanger sequencing by capillary electrophoresis and Amino Acid Sequences are guaranteed to be matched with NCBI database.

shRNA Clone Collection Publications

View selected publications citing GeneCopoeia’s OMICSLINK™ shRNA clone sets from the recent literature

2024

Li, J., et al. (2024). cGAS-ISG15-RAGE axis reprogram necroptotic microenvironment and promote lymphatic metastasis in head and neck cancer. Exp Hematol Oncol. DOI: 10.1186/s40164-024-00531-5 [Lentifect™ shRNA lentiviral particles targeting ISG15]
Yankey, A., et al. (2024). A novel partnership between lncTCF7 and SND1 regulates the expression of the TCF7 gene via recruitment of the SWI/SNF complex. Sci Rep. DOI: 10.1038/s41598-024-69792-8 [OMICSLINK™ shRNA clone set against Human WSPAR (NR_131252)]
Chen, H., et al. (2024). SETD8 inhibits apoptosis and ferroptosis of Ewing’s sarcoma through YBX1/RAC3 axis. Cell Death Dis. DOI: 10.1038/s41419-024-06882-5 [OMICSLINK™ shRNA clones targeting Human SETD8, YBX1, and RAC3]
Liu, X., et al. (2024). CDK4/6 inhibitors dephosphorylate RNF26 to stabilize TSC1 and increase the sensitivity of ccRCC to mTOR inhibitors. Br J Cancer. DOI: 10.1038/s41416-024-02750-3 [OMICSLINK™ shRNA clone against Human RNF26 and TSC1]
Lin, Z., et al. (2024). Hypoxia-induced cysteine metabolism reprogramming is crucial for the tumorigenesis of colorectal cancer. Redox Biol. DOI: 10.1016/j.redox.2024.103286 [OMICSLINK™ shRNA clone targeting SLC7A11, SLC1A5, ATF4, PERK and scrambled control]
Surana, S., et al. (2024). The tyrosine phosphatases LAR and PTPRδ act as receptors of the nidogen-tetanus toxin complex. EMBO J. DOI: 10.1038/s44318-024-00164-8 [OmicsLink™ Ptprf shRNA expression clone and scrambled control, Cat. No. MSH030014]
Doré, S., et al. (2024). Exploring the prognostic significance of arm-level copy number alterations in triple-negative breast cancer. Oncogene. DOI: 10.1038/s41388-024-03051-y [OMICSLINK™ shRNA expression clones plasmid (pLKO.1); OMICSLINK™ Lentiviral ORF expression clone and empty control, Cat. No. EX-Mm10838-Lv151-GS, pReceiver-Lv151]
Wei, H., et al. (2024). OLFM4 promotes the progression of intestinal metaplasia through activation of the MYH9/GSK3β/β-catenin pathway. Mol Cancer. DOI: 10.1186/s12943-024-02016-9 [OMICSLINK™ Human OLFM4 and MYH9 ORF expression clones, Cat. No.EX-Y2060-Lv201, EX-T1335-Lv242;OMICSLINK™ shRNA clone against Human OLFM4 and MYH9, Cat. No.HSH090725-LVRU6GP, HSH102697-LVRU6GP]
Chen, X., et al. (2024). Long non-coding RNA HOTAIR: from pan-cancer analysis to colorectal cancer-related uridine metabolism. Aging (Albany NY). DOI: 10.18632/aging.205781 [OMICSLINK™ Human UPP1（NM_003364）ORF expression clone, Cat. No.EX-Q0192-Lv242-B; OMICSLINK™ shRNA clone set against Human UPP1（NM_003364）, Cat. No.HSH111118-LVRU6GP]
Lang, B.J., et al. (2024). Heat shock protein 72 supports extracellular matrix production in metastatic mammary tumors. Cell Stress Chaperones. DOI: 10.1016/j.cstres.2024.04.006 [OMICSLINK™ shRNA clone against Human HSPA1A, Cat. No. HSH009077-LVRU6P]
Chen, J., et al. (2024). ELMO1 ameliorates intestinal epithelial cellular senescence via SIRT1/p65 signaling in inflammatory bowel disease-related fibrosis. Gastroenterol Rep (Oxf). DOI: 10.1093/gastro/goae045 [OMICSLINK™ shRNA clone set against Mus Elmo1(NM_080288), Cat.No.MSH092100-LVRU6GP]
Verkerke, A.R.P., et al. (2024). BCAA nitrogen flux in brown fat controls metabolic health independent of thermogenesis. Cell. DOI: 10.1016/j.cell.2024.03.030 [OmicsLink™ shRNA scrambled control clone, Cat. No. CSHCTR001-LVRU6GH]
Battistini, C., et al. (2024). Tumor microenvironment-induced FOXM1 regulates ovarian cancer stemness. Cell Death Dis. DOI: 10.1038/s41419-024-06767-7 [OmicsLink™ shRNA expression clones,Cat. No. HSH096566-LVRU6GP-c, HSH096566-LVRU6GP-e, CSHCTR001-LVRU6GP]
Cao, N., et al. (2024). LPCAT2 inhibits colorectal cancer progression via the PRMT1/SLC7A11 axis. Oncogene. DOI: 10.1038/s41388-024-02996-4 [OmicsLink™ LPCAT2 and PRMT1 shRNA expression clones]
Zhao, R., et al. (2024). Identification and characterization of intermediate states in mammalian neural crest cell epithelial to mesenchymal transition and delamination. eLife. DOI: 10.7554/eLife.92844 [OmicsLink™ shRNA expression clone, Cat. No. MSH100727-LVRU6MP]
Hansen, E., et al. (2024). Emerin deficiency drives MCF7 cells to an invasive phenotype. bioRxiv. DOI: 10.1101/2024.02.21.581379 [OmicsLink™ shRNA expression clone]
Coleman, M.F., et al. (2024). Hypoxia-mediated repression of pyruvate carboxylase drives immunosuppression. Breast Cancer Res. DOI: 10.1186/s13058-024-01854-1 [OmicsLink™ shRNA expression clone]
Suo, D., et al. (2024). HSPA4 upregulation induces immune evasion via ALKBH5/CD58 axis in gastric cancer. J Exp Clin Cancer Res. DOI: 10.1186/s13046-024-03029-4 [OMICSLINK™ Human HSPA4 ORF expression clone, Cat. No.EX-Z0153-Lv105; OMICSLINK™ shRNA clone against Human HSPA4, Cat. No.HSH009081-LVRU6GP; Lenti-Pac™ HIV expression packaging kit, Cat. No.LT001]
Tan, H., et al. (2024). Rare Mutations in CCDC7 Contribute to Early-Onset Preeclampsia by Inhibiting Trophoblast Migration and Invasion. J Pers Med. DOI: 10.3390/jpm14030253 [OMICSLINK™ shRNA clone set against Human CCDC7, Cat. No.HSH065439-LVRU6GP; Lenti-Pac™ HIV Expression Packaging Kit]
Zhang, Y., et al. (2024). CircGLIS3 promotes gastric cancer progression by regulating the miR-1343-3p/PGK1 pathway and inhibiting vimentin phosphorylation. J Transl Med. DOI: 10.1186/s12967-023-04625-2 [Lenti-Pac™ HIV Expression Packaging Kit; OMICSLINK™ shRNA lentivirus vector (psi-LVRU6GP/GFP/Puro)]
Luo, Y., et al. (2024). SARS-Cov-2 spike induces intestinal barrier dysfunction through the interaction between CEACAM5 and Galectin-9. Front Immunol. DOI: 10.3389/fimmu.2024.1303356 [OMICSLINK™ shRNA clones targeting CEACAM5]
Alves-Figueiredo, H., et al. (2024). Mitochondrial Ca2+ Uniporter–Dependent Energetic Dysfunction Drives Hypertrophy in Heart Failure. JACC Basic Transl Sci. DOI: 10.1016/j.jacbts.2024.01.007 [OMICSLINK™ shRNA clones targeting MCU]
Han, J-Y., et al. (2024). Desmoglein 2 and desmocollin 2 depletions promote malignancy through distinct mechanisms in triple-negative and luminal breast cancer. BMC Cancer. DOI: 10.1186/s12885-024-12229-2 [OMICSLINK™ shRNA clones targeting Dsg2 and Dsc2; Lenti-Pac™ HIV Expression Packaging Kit]
Qi, Y., et al. (2024). Neuroprotective effect of acetoxypachydiol against oxidative stress through activation of the Keap1-Nrf2/HO-1 pathway. BMC Complement Med Ther. DOI: 10.1186/s12906-024-04474-6 [OMICSLINK™ siRNA clones targeting Nrf2]
Zhu, S., et al. (2024). RIPK3 deficiency blocks R-2-hydroxyglutarate–induced necroptosis in IDH-mutated AML cells. Sci Adv. DOI: 10.1126/sciadv.adi1782 [OMICSLINK™ Lentiviral shRNA clones targeting RIPK1]
Wang, X., et al. (2024). GATA3 functions downstream of BRCA1 to promote DNA damage repair and suppress dedifferentiation in breast cancer. BMC Biol. DOI: 10.1186/s12915-024-01881-6 [OMICSLINK™ shRNA clones targeting Gata3]
Peng, Y., et al. (2024). POLQ inhibition attenuates the stemness and ferroptosis resistance in gastric cancer cells via downregulation of dihydroorotate dehydrogenase. Cell Death Dis. DOI: 10.1038/s41419-024-06618-5 [OMICSLINK™ shRNA clone against Human POLQ, Cat. No.HSH000855-LVRU6GP]
Chang, X-H., et al. (2024). Significance of hepatitis B virus capsid dephosphorylation via polymerase. J Biomed Sci. DOI: 10.1186/s12929-024-01022-9 [OMICSLINK™ shRNA clone set against Human BECN1]
Wang, X., et al. (2024). JNK signaling mediates acute rejection via activating autophagy of CD8+ T cells after liver transplantation in rats. Front Immunol. DOI: 10.3389/fimmu.2024.1359859 [OMICSLINK™ shRNA clone set against Human BECN1]
Bugara, B., et al. (2024). Silencing of the PHLDA1 leads to global proteome changes and differentiation pathways of human neuroblastoma cells. Front Pharmacol. DOI: 10.3389/fphar.2024.1351536 [OMICSLINK™ PHLDA1 shRNA clone, Cat. No. HSH005478-nH1-a, shRNA scrambled control for psi-nH1 and psi-H1, Cat. No. CSHCTR001-nH1, CSHCTR001-CH1]
Baek, J-W., et al. (2024). Dualistic Effects of PRKAR1A as a Potential Anticancer Target in Cancer Cells and Cancer-Derived Stem Cells. Int J Mol Sci. DOI: 10.3390/ijms25052876 [OMICSLINK™ PRKAR1A-LVRU6GP shRNA clone and scramble control]
Wang, S., et al. (2024). FHL2 promotes the aggressiveness of lung adenocarcinoma by inhibiting autophagy via activation of the PI3K/AKT/mTOR pathway. Thorac Cancer. DOI: 10.1111/1759-7714.15234 [OMICSLINK™ FHL2 shRNA clone and scramble control]
Hendrixson, J.A., et al. (2024). Loss of chaperone‐mediated autophagy does not alter age‐related bone loss in male mice. FASEB Bioadv. DOI: 10.1096/fba.2023-00133 [OMICSLINK™ shRNA scramble control]
Ying Zhang, et al. 2024. Salvianolic Acid B Significantly Suppresses the Migration of Melanoma Cells via Direct Interaction with β-Actin. Molecules. DOI: 10.3390/molecules29040906 [OMICSLINK™ shRNA clone against Human β-actin]
Joseph Mazar, et al. 2024.The Oncolytic Activity of Zika Viral Therapy in Human Neuroblastoma In Vivo Models Confers a Major Survival Advantage in a CD24-dependent Manner. Cancer Res Commun.DOI:10.1158/2767-9764.CRC-23-0221[CD24 molecule, Cat. No.HSH070733-CH1-a, b, and c; shRNA scrambled control clone for psi-H1, Cat. No.CSHCTR001-CH1]
Qi Yang, et al. 2024.PPIP5K2 Facilitates Proliferation and Metastasis of Non-Small Lung Cancer (NSCLC) through AKT Signaling Pathway. Cancers (Basel).DOI:10.3390/cancers16030590[The PPIP5K2 overexpression and short-hairpin RNA (shRNA)]
Huimou Chen, et al. 2024.AURKA inhibition induces Ewing’s sarcoma apoptosis and ferroptosis through NPM1/YAP1 axis. Cell Death Dis.DOI:10.1038/s41419-024-06485-0[The short hairpin RNAs (shRNAs) of AURKA; NPM1; and YAP1]
Yanan Gu, et al. 2024.CYLD regulates cell ferroptosis through Hippo/YAP signaling in prostate cancer progression. Cell Death Dis.DOI:10.1038/s41419-024-06464-5[OMICSLINK™ CYLD shRNA clone and scramble control; Lentifect™ Lentiviral particles overexpressing CYLD]
Arnaud Bakaric, et al. 2024.CIC-DUX4 Chromatin Profiling Reveals New Epigenetic Dependencies and Actionable Therapeutic Targets in CIC-Rearranged Sarcomas. Cancers (Basel).DOI:10.3390/cancers16020457[OMICSLINK™ EP300 shRNA clone and scramble control, Cat. No.HSH088760- LVRU6GP]
Gisele Nishiguchi, et al. 2024.Selective CK1α degraders exert antiproliferative activity against a broad range of human cancer cell lines. Nat Commun.DOI:10.1038/s41467-024-44698-1[OMICSLINK™ CSNK1A1 shRNA clone and scramble control, Cat. No.CSHCTR001-1-LVRU6GP; HSH059457-LVRU6GP]
Jinbin Chen, et al. 2024.Circular RNA hsa_circ_0050386 suppresses non-small cell lung cancer progression via regulating the SRSF3/FN1 axis. J Transl Med.DOI:10.1186/s12967-023-04812-1[OMICSLINK™ hsa_circ_0050386 shRNA clone; Lenti-Pac HIV Expression Packaging Kit, Cat. No.LT001]
Gu-Choul Shin, et al. 2024.PRKCSH contributes to TNFSF resistance by extending IGF1R half-life and activation in lung cancer. Exp Mol Med.DOI:10.1038/s12276-023-01147-1[OMICSLINK™ Human PRKCSH-LVRU6GP shRNA clone]
Yulong Hong, et al. 2024.Identification of molecular subtypes and diagnostic model in clear cell renal cell carcinoma based on collagen-related genes may predict the response of immunotherapy. Front Pharmacol.DOI:10.3389/fphar.2024.1325447[OMICSLINK™ Human SCGN shRNA clone and scramble control]
Long Wei, et al. 2024.TM9SF1 promotes bladder cancer cell growth and infiltration. World J Clin Oncol.DOI:10.5306/wjco.v15.i2.302[OMICSLINK™ shRNA clone set against Human TM9SF1]
Kunxiang Gong, et al. 2024.ZSWIM4 inhibition improves chemosensitivity in epithelial ovarian cancer cells by suppressing intracellular glycine biosynthesis. J Transl Med.DOI:10.1186/s12967-024-04980-8[OMICSLINK™ shRNA clone set against Human ZSWIM4; GLuc-ON™ Human ZSWIM4 promoter-reporter clone; OMICSLINK™ Human FOXK1 ORF expression clone]
Ye Hu, et al. 2024.INHBA(+) cancer-associated fibroblasts generate an immunosuppressive tumor microenvironment in ovarian cancer. NPJ Precis Oncol.DOI:10.1038/s41698-024-00523-y[OMICSLINK™ shRNA clone set against Mouse INHBA, Cat. No.MSH093015-CU6.]
Leilei Zhao, et al. 2024.IGFBP3 induces PD-L1 expression to promote glioblastoma immune evasion. Cancer Cell Int.DOI:10.1186/s12935-024-03234-3[OMICSLINK™ Human IGFBP3 ORF expression clone; OMICSLINK™ Human IGFBP3 lentiviral shRNA clone]
Wen Hu, et al. 2024.PPM1G promotes cell proliferation via modulating mutant GOF p53 protein expression in hepatocellular carcinoma. iScience.DOI:10.1016/j.isci.2024.109116[OMICSLINK™ PPM1G Lentiviral ORF expression clone and positive control, Cat. No.EX-A1751-Lv201, EX-EGFP-LV201; OMICSLINK™ PPM1G shRNA clone Cat. No.HSH013921-LVRU6GP]

2023

Navarro-Lobato, I., et al. (2023). Promotion of structural plasticity in area V2 of visual cortex prevents against object recognition memory deficits in aging and Alzheimer’s disease rodents. Neural Regen Res. DOI: 10.4103/1673-5374.389301 [AAVPrime™ AAV particles targeting Rat Bdnf and Mouse Bdnf, Cat. No. AA10-RSH067171-AV03-200, AA10-MSH026637-AV03-200]
Chunming Wang, et al. 2023. Ailanthone synergizes with PARP1 inhibitor in tumour growth inhibition through crosstalk of DNA repair pathways in gastric cancer. J Cell Mol Med. DOI: 10.1111/jcmm.18033 [OMICSLINK™ shRNA clone vector]
Xin-Yue Zhang, et al. 2023. NR0B1 suppresses ferroptosis through upregulation of NRF2/c-JUN-CBS signaling pathway in lung cancer cells. Am J Cancer Res. [OMICSLINK™ Lentiviral ORF expression clones; OMICSLINK™ shRNA clones targeting NR0B1 (shNR0B1) and NRF2 (shNRF2)]
Minlan Yang, et al. 2023.Intermittent Hypoxia Promotes TAM-Induced Glycolysis in Laryngeal Cancer Cells via Regulation of HK1 Expression through Activation of ZBTB10. Int J Mol Sci.DOI:10.3390/ijms241914808[OMICSLINK™ shRNA clone against Human HK1; OMICSLINK™ Human HK1 ORF expression clone, Cat. No.EX-T0174-Lv242-B; OMICSLINK™ Human ZBTB10 ORF expression clone, Cat. No.EX-Z6181-Lv157]
Li Xiao, et al. 2023.Knockdown of Secernin 1 inhibit cell invasion and migration by activating the TGF-β/Smad3 pathway in oral squamous cell carcinomas. Sci Rep.DOI:10.1038/s41598-023-41504-8[OMICSLINK™ shRNA clone against Human SCRN1; Lentifect™ Lentiviral particles expressing shRNA targeting Human SCRN1]
Claudia Alexandra Dumitru, et al. 2023.Progesterone Receptor Membrane Component 1 (PGRMC1) Modulates Tumour Progression; the Immune Microenvironment and the Response to Therapy in Glioblastoma. Cells.DOI:10.3390/cells12202498[OMICSLINK™ shRNA clone against Human PGRMC1, Cat. No.HSH091094-nH1]
Song Wu, et al. 2023.LINC01343 targets miR-526b-5p to facilitate the development of hepatocellular carcinoma by upregulating ROBO1. Sci Rep.DOI:10.1038/s41598-023-42317-5[OMICSLINK™ shRNA clone against Human LINC01343; Lentifect™ Lentiviral particles expressing shRNA targeting Human LINC01343]
Qingyun Liao, et al. 2023.FTH1 indicates poor prognosis and promotes metastasis in head and neck squamous cell carcinoma. PeerJ. DOI:10.7717/peerj.16493[OMICSLINK™ FTH1 shRNA expression clones; Lenti-Pac™ HIV lentivirus packaging kit]
Jin Ma, et al. 2023.CHCHD4-TRIAP1 regulation of innate immune signaling mediates skeletal muscle adaptation to exercise. Cell Rep. DOI:10.1016/j.celrep.2023.113626[OMICSLINK™ lentiviral shRNA clones and control vector; OMICSLINK™ Mouse CHCHD4 ORF expression clone and control vector; OMICSLINK™ lentiviral shRNA VDAC1 and TRIAP1 clones and control vector]
Yuanyuan Chen, et al. 2023.USP4 promotes the proliferation and glucose metabolism of gastric cancer cells by upregulating PKM2. PLoS One. DOI:10.1371/journal.pone.0290688[OMICSLINK™ USP4 and PKM2 shRNA expression clones]
Jia-Jun Li, et al. 2023.The liver microenvironment orchestrates FGL1-mediated immune escape and progression of metastatic colorectal cancer. Nat Commun.DOI:10.1038/s41467-023-42332-0[OMICSLINK™ Human or Mouse OTUD1, p65 ORF expression clone; OMICSLINK™ shRNA clone against Human or Mouse OTUD1, p65; GLuc-ON™ Human or Mouse OTUD1 promoter-reporter clone, Cat. No.MPRM62853]
Xiao lan Tan, et al. 2023.NR0B1 augments sorafenib resistance in hepatocellular carcinoma through promoting autophagy and inhibiting apoptosis. Cancer Sci.DOI:10.1111/cas.16029[Lentifect™ Lentiviral particles Human NR0B1 ORF expression clone, Cat. No.LPP-CS-A0573-Lv201-01-100; Lentifect™ Lentiviral particles expressing shRNA targeting Human NR0B1, Cat. No.LPP-CS-HSH004563-LVRU6GP-01-200]
Qingqing Zhou, et al. 2023.VPS35 promotes gastric cancer progression through integrin/FAK/SRC signalling-mediated IL-6/STAT3 pathway activation in a YAP-dependent manner. Oncogene.DOI:10.1038/s41388-023-02885-2[OMICSLINK™ Lentiviral ORF expression clones; OMICSLINK™ ORF expression clones plasmid]
Borja Gomez Ramos, et al. 2023.Multiomics analysis identifies novel facilitators of human dopaminergic neuron differentiation. EMBO Rep.DOI:10.1038/s44319-023-00024-2[OMICSLINK™ Lentiviral ORF expression clones; OMICSLINK™ lentiviral shRNA clones]
Siyuan Chen, et al. 2023.JMJD6 in tumor-associated macrophage regulates macrophage polarization and cancer progression via STAT3/IL-10 axis. Oncogene.DOI:10.1038/s41388-023-02781-9[Lentifect™ lentiviral particles expressing shRNA targeting JMJD6]
Zang, L., et al. (2023). PHACTR1 promotes the mobility of papillary thyroid carcinoma cells by inducing F-actin formation. Heliyon. doi: 10.1016/j.heliyon.2023.e20461 [OMICSLINK™ Human PHACTR1 ORF expression clone; OMICSLINK™ shRNA clone set against Human PHACTR1]
Guo, J., et al. (2023). TRIM6: An Upregulated Biomarker with Prognostic Significance and Immune Correlations in Gliomas. Biomolecules. doi: 10.3390/biom13091298 [OMICSLINK™ Human TRIM6 ORF expression clone; OMICSLINK™ shRNA clone set against Human TRIM6]
Zhang, G., et al. (2023). Mechanical confinement promotes heat resistance of hepatocellular carcinoma via SP1/IL4I1/AHR axis. Cell Rep Med. doi: 10.1016/j.xcrm.2023.101128 [OMICSLINK™ SP1 shRNA expression clone; OMICSLINK™ IL4I1, ZNF667-AS1 ORF expression clone]
Zhao, R., et al. (2023). Identification and characterization of intermediate states in mammalian neural crest cell epithelial to mesenchymal transition and delamination. bioRxiv. doi: 10.1101/2023.10.26.564204 [Lentifect™ lentiviral particles expressing shRNA clone set targeting Dlc1]
Zeng, F., et al. (2023). MALAT1 promotes FOXA1 degradation by competitively binding to miR-216a-5p and enhancing neuroendocrine differentiation in prostate cancer. Transl Oncol. doi: 10.1016/j.tranon.2023.101807 [Lentifect™ lentiviral particles targeting MALAT1; Lentifect™ lentiviral particles expressing shRNA targeting MALAT1, ZFP91 ]
Zhang, Y., et al. (2023). Ablation of the GDP-fucose transporter suppresses lung cancer cell proliferation and migration by reducing expression of PD-L1. J Cancer. doi: 10.7150/jca.84652 [OMICSLINK™ shRNA clones targeting SLC35C1]
Dai, Z., et al. (2023). Interleukin-19 promotes bone resorption by suppressing osteoprotegerin expression in BMSCs in a lipopolysaccharide-induced bone loss mouse model. Bone Joint Res. doi: 10.1302/2046-3758.1211.BJR-2023-0101.R1 [siRNAs]
Cha, J., et al. (2023). Species-specific roles for the MAFA and MAFB transcription factors in regulating islet β cell identity. JCI Insight. doi: 10.1172/jci.insight.166386 [OMICSLINK™ MAFA shRNA expression clone]
Wang, P., et al. (2023). Icariin activates far upstream element binding protein 1 to regulate hypoxia-inducible factor-1α and hypoxia-inducible factor-2α signaling and benefits chondrocytes. PeerJ. doi: 10.7717/peerj.15917 [OMICSLINK™ shRNA controls]
Sugiura, K., et al. (2023). LIN28B promotes cell invasion and colorectal cancer metastasis via CLDN1 and NOTCH3. JCI Insight. doi: 10.1172/jci.insight.167310 [OMICSLINK™ shRNA controls]
Bahia, R.K., et al. (2023). Epigenetic and molecular coordination between HDAC2 and SMAD3-SKI regulates essential brain tumour stem cell characteristics. Nat Commun. doi: 10.1038/s41467-023-40776-y [OMICSLINK™ shRNA controls]
Yang, Q., et al. (2023). N4‐Acetylcytidine Drives Glycolysis Addiction in Gastric Cancer via NAT10/SEPT9/HIF‐1α Positive Feedback Loop. Advanced Science doi: 10.1002/advs.202300898 [Lenti-Pac™ HIV Expression Packaging Kit; OMICSLINK™ lentiviral shRNA clone; miTarget™ 3′ UTR Clone; Luc-Pair™ Duo-Luciferase HS Assay Kit]
Fan, Q., et al. (2023). Hyper α2,6‐Sialylation Promotes CD4+ T‐Cell Activation and Induces the Occurrence of Ulcerative Colitis. Advanced Science doi: 10.1002/advs.202302607 [OMICSLINK™ shRNA clone]
Hao, X., et al. (2023). BI-907828, a novel potent MDM2 inhibitor, inhibits glioblastoma brain tumor stem cells in vitro and prolongs survival in orthotopic xenograft mouse models. Neuro-Oncology doi: 10.1093/neuonc/noac271 [OMICSLINK™ shRNA clones]
Li, F., et al. (2023). RIPK1-dependent necroptosis promotes vasculogenic mimicry formation via eIF4E in triple-negative breast cancer. Cell Death Dis doi: 10.1038/s41419-023-05841-w [Lenti-Pac™ HIV Expression Packaging Kit; OMICSLINK™ RIPK1, EIF4E ORF expression clone; OMICSLINK™ RIPK1 shRNA expression clones]
Zhou, L., et al. (2023). Syntaxin-6 promotes the progression of hepatocellular carcinoma and alters its sensitivity to chemotherapies by activating the USF2/LC3B axis. Int J Biol Sci doi: 10.7150/ijbs.86636 [OMICSLINK™ STX6 ORF expression clone; OMICSLINK™ STX6 shRNA clone]
Yan, B., et al. (2023). The YTHDC1/GLUT3/RNF183 axis forms a positive feedback loop that modulates glucose metabolism and bladder cancer progression. Exp Mol Med doi: 10.1038/s12276-023-00997-z [OMICSLINK™ YTHDC1, GLUT3, RNF183 ORF expression clone; OMICSLINK™ YTHDC1,RNF183 shRNA clone set]
Liu, X., et al. (2023). Loss of function of GATA3 regulates FRA1 and c-FOS to activate EMT and promote mammary tumorigenesis and metastasis. Cell Death Dis doi: 10.1038/s41419-023-05888-9 [OMICSLINK™ Gata3 shRNA expression clones; OMICSLINK™ FOS ORF expression clone]
Wu, T., et al. (2023). miR-30e-5p-mediated FOXD1 promotes cell proliferation by blocking cellular senescence and apoptosis through p21/CDK2/Rb signaling in head and neck carcinoma. Cell Death Discov doi: 10.1038/s41420-023-01571-2 [OMICSLINK™ shRNA clones targeting FOXD1 and control]
Santos, F.F., et al. (2023). HIV-1-induced nuclear invaginations mediated by VAP-A; ORP3; and Rab7 complex explain infection of activated T cells. Nat Commun doi: 10.1038/s41467-023-40227-8 [OMICSLINK™ shRNA clones targeting VAP-A, VAP-B, ORP3 and control]
Pilgrim, A.A., et al. (2023). The yes-associated protein (YAP) is associated with resistance to anti-GD2 immunotherapy in neuroblastoma through downregulation of ST8SIA1. Oncoimmunology doi: 10.1080/2162402X.2023.2240678 [OMICSLINK™ ST8SIA1 shRNA targeting clones]
Ma, W., et al. (2023). Dermokine mutations contribute to epithelial-mesenchymal transition and advanced melanoma through ERK/MAPK pathways. PLoS One doi: 10.1371/journal.pone.0285806 [OMICSLINK™ DMKN shRNA targeting clones]
García-Hernández, B., et al. (2023). Txnip expression promotes JNK-mediated neuronal death in response to reactive oxygen species. Front Mol Neurosci doi: 10.3389/fnmol.2023.1210962 [OMICSLINK™ Txnip shRNA clone]
Li, L., et al. (2023). FSCN1 promotes proliferation; invasion and glycolysis via the IRF4/AKT signaling pathway in oral squamous cell carcinoma. BMC Oral Health doi: 10.1186/s12903-023-03191-9 [OMICSLINK™ FSCN1 shRNA clone; Lenti-Pac™ HIV expression packaging kit]
Li, C., et al. (2023). Cutaneous squamous cell carcinoma-derived extracellular vesicles exert an oncogenic role by activating cancer-associated fibroblasts. Cell Death Discov doi: 10.1038/s41420-023-01555-2 [OMICSLINK™ RAB27A shRNA clone]
Cao, W., et al. (2023). Knockdown of FUT11 inhibits the progression of gastric cancer via the PI3K/AKT pathway. Heliyon doi: 10.1016/j.heliyon.2023.e17600 [OMICSLINK™ FUT11 shRNA clone; OMICSLINK™ COL6A3 ORF expression clone]
Yap, C.C., et al. (2023). Disruption of Golgi markers by two RILP-directed shRNAs in neurons: A new role for RILP or a neuron-specific off-target phenotype? J Biol Chem doi: 10.1016/j.jbc.2023.104916 [OMICSLINK™ RILP shRNA clone set]
Guo, M., et al. (2023). Identification of the prognostic biomarkers and their correlations with immune infiltration in colorectal cancer through bioinformatics analysis and in vitro experiments. Heliyon doi: 10.1016/j.heliyon.2023.e17101 [OMICSLINK™ AR, EPPK1 and JUP shRNA clone set]
Yang, L., et al. (2023). Androgen dihydrotestosterone promotes bladder cancer cell proliferation and invasion via EPPK1-mediated MAPK/JUP signalling. Cell Death Dis doi: 10.1038/s41419-023-05882-1 [OMICSLINK™ AR, EPPK1 and JUP shRNA clone set]
Wu, X., et al. (2023). Regulating the cell shift of endothelial cell-like myofibroblasts in pulmonary fibrosis. Eur Respir J doi: 10.1183/13993003.01799-2022 [OMICSLINK™ FoxA2 Lentiviral ORF expression clone; OMICSLINK™ siRNA FoxA2]
Zhou, Q., et al. (2023). HNF4A-BAP31-VDAC1 axis synchronously regulates cell proliferation and ferroptosis in gastric cancer. Cell Death Dis doi: 10.1038/s41419-023-05868-z [OMICSLINK™ NRF2 shRNA expression clone]
Lin, M., et al. (2023). TRIM55 inhibits colorectal cancer development via enhancing protein degradation of c‐Myc. Cancer Med doi: 10.1002/cam4.6020 [OMICSLINK™ siRNA]
Wei, Y., et al. (2023). LncRNA XIST promotes adjuvant-induced arthritis by increasing the expression of YY1 via miR-34a-5p. Arch Rheumatol doi: 10.46497/ArchRheumatol.2022.9250 [miExpress™ inhibitor clone; OMICSLINK™ lentiviral shRNA clone; OMICSLINK™ ORF expression clones; Lenti-Pac™ HIV Expression Packaging Kit]
Zhu,Y., et al. (2023). Research on Radiosensitivity of the Protein Kinase B Signaling Pathway in Cervical Cancer. Comput Math Methods Med doi: 10.1155/2021/6350038 [Lenti-Pac™ HIV Expression Packaging Kit; OMICSLINK™ shRNA clone]
Zhang, X., et al. (2023). IGFBP3 induced by the TGF-β/EGFRvIII transactivation contributes to the malignant phenotype of glioblastoma. iScience doi: 10.1016/j.isci.2023.106639 [Lentifect™ shRNA lentiviral particles]
Roganowicz, M., et al. (2023). BAZ2A-RNA mediated association with TOP2A and KDM1A represses genes implicated in prostate cancer. Life Sci Alliance doi: 10.26508/lsa.202301950 [OMICSLINK™ mouse BAZ2A ORF expression clone; OMICSLINK™ BAZ2A shRNA expression clone]
Yang, Y., et al. (2023). PLCG2 can exist in eccDNA and contribute to the metastasis of non-small cell lung cancer by regulating mitochondrial respiration. Cell Death Dis doi: 10.1038/s41419-023-05755-7 [OMICSLINK™ PLCG2 ORF expression clone and its negative control; PLCG2-siRNA]
Wang, S., et al. (2023). miRNA-27a is essential for bone remodeling by modulating p62-mediated osteoclast signaling. eLife doi: 10.7554/eLife.79768 [miExpress™ miRNA precursor clone; OMICSLINK™ Sqstm1 shRNA expression clones]
Liu, P., et al. (2023). FUT2 promotes the tumorigenicity and metastasis of colorectal cancer cells via the Wnt/β-catenin pathway. Int J Oncol doi: 10.3892/ijo.2023.5483 [vectors (pGPU6/GFP/Neo-FUT2 or pGPU6/GFP/Neo-shNC)]
Seong, C-S., et al. (2023). Loss of the endocytic tumor suppressor HD-PTP phenocopies LKB1 and promotes RAS-driven oncogenesis. bioRxiv doi: 10.1101/2023.01.26.525772 [Lentifect™ shRNA lentiviral particles]
Espadas, I., et al. (2023). SLAMR; a synaptically targeted lncRNA; facilitates the consolidation of contextual fear memory. Res Sq doi: 10.21203/rs.3.rs-2489387/v1 [OMICSLINK™ shRNA clones]
Cordovado, A., et al. (2023). SEMA6B variants cause intellectual disability and alter dendritic spine density and axon guidance. Hum Mol Genet doi: 10.1093/hmg/ddac114 [OMICSLINK™ shRNA clones]
Wang, X., et al. (2023). Long Noncoding RNAs Hepatocyte Nuclear Factor 4A Antisense RNA 1 and Hepatocyte Nuclear Factor 1A Antisense RNA 1 Are Involved in Ritonavir-Induced Cytotoxicity in Hepatoma Cells. Drug Metab Dispos doi: 10.1124/dmd.121.000693 [OMICSLINK™ shRNA clone; OMICSLINK™ ORF expression clone]
Zhou, M., et al. (2023). Adiponectin protects skeletal muscle from ischaemia–reperfusion injury in mice through miR‐21/PI3K/Akt signalling pathway. Int Wound J doi: 10.1111/iwj.14022 [OMICSLINK™ shRNA clones]
Cao, F., et al. (2023). Celastrol Treatment Ameliorated Acute Ischemic Stroke-Induced Brain Injury by Microglial Injury Inhibition and Nrf2/HO-1 Pathway Activations. Biomed Res Int doi: 10.1155/2023/1076522 [OMICSLINK™ lentiviral shRNA clone set against Nrf2]
Wang, Q., et al. (2023). HnRNPAB is an independent prognostic factor in non‑small cell lung cancer and is involved in cell proliferation and metastasis. Oncol Lett doi: 10.3892/ol.2023.13801 [psi-LVRU6GP vector]
Khanal, P., et al. (2023). Gas7 Is a Novel Dendritic Spine Initiation Factor. eNeuro doi: 10.1523/ENEURO.0344-22.2023 [OMICSLINK™ Gas7 shRNA expression clones; shRNA scrambled control clone for psi-H1]
Li, T., et al. (2023). Nanoparticle-mediated TRPV1 channel blockade amplifies cancer thermo-immunotherapy via heat shock factor 1 modulation. Nat Commun doi: 10.1038/s41467-023-38128-x [OMICSLINK™ TRPV1 shRNA expression clone]
Chen, J., et al. (2023). Increased FOXM1 Expression was Associated with the Prognosis and the Recruitment of Neutrophils in Endometrial Cancer. J Immunol Res doi: 10.1155/2023/5437526 [OMICSLINK™ lentiviral FOXM1 shRNA expression clone set]
Li, J., et al. (2023). Knockdown of NCAPG promotes the apoptosis and inhibits the invasion and migration of triple‑negative breast cancer MDA‑MB‑231 cells via regulation of EGFR/JAK/STAT3 signaling. Exp Ther Med doi: 10.3892/etm.2023.11818 [OmicsLink™ NCAPG shRNA expression clones]
Bodnar-Wachtel, M., et al. (2023). Inflammasome-independent NLRP3 function enforces ATM activity in response to genotoxic stress. Life Sci Alliance doi: 10.26508/lsa.202201494 [OMICSLINK™ shRNA clones targeting NLRP3]
Nguyen, T.T.M., et al. (2023). GPX8 regulates clear cell renal cell carcinoma tumorigenesis through promoting lipogenesis by NNMT. J Exp Clin Cancer Res doi: 10.1186/s13046-023-02607-2 [OMICSLINK™ NNMT shRNA expression clones]
Huang, X., et al. (2023). Downregulation of LncRNA GCLC-1 Promotes Microcystin-LR-Induced Malignant Transformation of Human Liver Cells by Regulating GCLC Expression. Toxics doi: 10.3390/toxics11020162 [OMICSLINK™ shRNA clones targeting LOC101927136; Lenti-Pac™ HIV Expression Packaging Kit]
Lin, Y., et al. (2023). The FGFR1 Signaling Pathway Upregulates the Oncogenic Transcription Factor FOXQ1 to Promote Breast Cancer Cell Growth. Int J Biol Sci doi: 10.7150/ijbs.74574 [OMICSLINK™ FOXQ1 shRNA expression clones]
Soni, S., et al. (2023). MAPKAPK2-centric transcriptome profiling reveals its major role in governing molecular crosstalk of IGFBP2; MUC4; and PRKAR2B during HNSCC pathogenesis. Comput Struct Biotechnol J doi: 10.1016/j.csbj.2023.01.039 [scrambled control vector CSHCTR001-CU6]
Lazo, O.M., et al. (2023). Rab10 regulates the sorting of internalised TrkB for retrograde axonal transport. eLife doi: 10.7554/eLife.81532 [OMICSLINK™ Rab10 shRNA expression clones]
Liu, Y., et al. Porphyromonas gingivalis promotes malignancy and chemo-resistance via GSK3β-mediated mitochondrial oxidative phosphorylation in human esophageal squamous cell carcinoma. Transl Oncol doi: 10.1016/j.tranon.2023.101656 [OMICSLINK™ shRNA clones; empty vector control plasmid; EndoFectin™ Lenti]
Zhu, S., et al. HOXB3 drives WNT-activation associated progression in castration-resistant prostate cancer. Cell Death Dis doi: 10.1038/s41419-023-05742-y [OMICSLINK™ shRNA clones targeting HOXB3 and APC]

2022

Shia, D.W., et al. (2022). Targeting PEA3 transcription factors to mitigate small cell lung cancer progression. Oncogene doi: 10.1038/s41388-022-02558-6 [Lentifect™ shRNA lentiviral particles]
Yan, Y., et al. (2022). Dopamine receptor D3 is related to prognosis in human hepatocellular carcinoma and inhibits tumor growth. BMC Cancer doi: 10.1186/s12885-022-10368-y [OMICSLINK™ shRNA expression clones; Lenti-Pac™ HIV Expression Packaging Kit; OMICSLINK™ DRD3 ORF expression clones; Control vector (with EGFP) for pReceiver-Lv105]
Papadas, A., et al. (2022). Stromal remodeling regulates dendritic cell abundance and activity in the tumor microenvironment. Cell Rep doi: 10.1016/j.celrep.2022.111201 [OMICSLINK™ lentiviral shRNA clone set against Vcan]
Li, W., et al. (2022). YTHDC1 is downregulated by the YY1/HDAC2 complex and controls the sensitivity of ccRCC to sunitinib by targeting the ANXA1-MAPK pathway. J Exp Clin Cancer Res doi: 10.1186/s13046-022-02460-9 [OMICSLINK™ shRNA clones]
Tan, X.Y., et al. (2022). Circ0038632 modulates MiR-186/DNMT3A axis to promote proliferation and metastasis in osteosarcoma. Front Oncol doi: 10.3389/fonc.2022.939994 [OMICSLINK™ shRNA clones; miExpress™ miRNA mimics; miArrest™ miRNA inhibitors]
Wang, Y.L., et al. (2022). KCTD7 mutations impair the trafficking of lysosomal enzymes through CLN5 accumulation to cause neuronal ceroid lipofuscinoses. Sci Adv doi: 10.1126/sciadv.abm5578 [OMICSLINK™ shRNA clones targeting KCTD7 and CLN5 ORF expression clones]
Laubitz, D., et al. (2022). Decreased NHE3 expression in colon cancer is associated with DNA damage; increased inflammation and tumor growth. Sci Rep doi: 10.1038/s41598-022-19091-x [HSH055571-LvU6]
Zhong, L.Z., et al. (2022). PRRX1 promotes colorectal cancer stemness and chemoresistance via the JAK2/STAT3 axis by targeting IL-6. J Gastrointest Oncol doi: 10.21037/jgo-22-1137 [OMICSLINK™ shRNA clones targeting PRRX1 ORF expression clones]
Zhang, Y.Q., et al. (2022). FUT2 Facilitates Autophagy and Suppresses Apoptosis via p53 and JNK Signaling in Lung Adenocarcinoma Cells. Cells doi: 10.3390/cells11244031 [HSH058626-CU6; CSHCTR001-CU6]
Li, W.C., et al. (2022). Syntaxin-6; a Reliable Biomarker for Predicting the Prognosis of Patients with Cancer and the Effectiveness of Immunotherapy. Cancers (Basel) doi: 10.3390/cancers15010027 [OMICSLINK™ shRNA clones targeting STX6]
Yuan, G.S., et al. (2022). Regulator of G protein signaling 12 drives inflammatory arthritis by activating synovial fibroblasts through MYCBP2/KIF2A signaling. Mol Ther Nucleic Acids doi: 10.1016/j.omtn.2022.12.017 [OMICSLINK™ shRNA clones targeting RGS12]
Zhang, B.Y., et al. (2022). The chromatin remodeler CHD6 promotes colorectal cancer development by regulating TMEM65-mediated mitochondrial dynamics via EGF and Wnt signaling. Cell Discov doi: 10.1038/s41421-022-00478-z [HSH020531-LVRU6GP-a/b]
Zeng, T-T., et al. (2022). HN1L/AP-2γ/PLK1 signaling drives tumor progression and chemotherapy resistance in esophageal squamous cell carcinoma. Cell Death Dis doi: 10.1038/s41419-022-05478-1 [HSH022039-LVRU6GP-b]
Wang, L., et al. (2022). All-trans retinoic acid enhances the cytotoxic effect of decitabine on myelodysplastic syndromes and acute myeloid leukaemia by activating the RARα-Nrf2 complex. Br J Cancer doi: 10.1038/s41416-022-02074-0 [OMICSLINK™ lentiviral shRNA clone set against RARA]
Maione， A.S., et al. (2022). Ca2+ dysregulation in cardiac stromal cells sustains fibro-adipose remodeling in Arrhythmogenic Cardiomyopathy and can be modulated by flecainide. J Transl Med doi: 10.1186/s12967-022-03742-8 [OMICSLINK™ lentiviral shRNA clone set against human PKP2]
Luo, N., et al. (2022). SRPX2 Promotes Tumor Proliferation and Migration via the FAK Pathway in Papillary Thyroid Carcinoma. J Oncol doi: 10.1155/2022/5821545 [OMICSLINK™ shRNA clones targeting SRPX2]
Sakaguchi, M., et al. (2022). Phosphatase protector alpha4 (α4) is involved in adipocyte maintenance and mitochondrial homeostasis through regulation of insulin signaling. Nat Commun doi: 10.1038/s41467-022-33842-4 [scrambled control vector]
Huo, U.M., et al. (2022). GJB3 promotes pancreatic cancer liver metastasis by enhancing the polarization and survival of neutrophil. Front Immunol doi: 10.3389/fimmu.2022.983116 [OMICSLINK™ shRNA clones]
Steiro, I., et al. (2022). The serine protease matriptase inhibits migration and proliferation in multiple myeloma cells. Oncotarget doi: 10.18632/oncotarget.28300 [ORF EXPRESS Gateway PLUS shuttle clone]
Deng, R.X., et al. (2022). Downregulation of TUSC3 promotes EMT and hepatocellular carcinoma progression through LIPC/AKT axis. J Transl Med doi: 10.1186/s12967-022-03690-3 [pEZ-Lv105 vector and the psi-LVRH1GP shRNA lentiviral vector]
Huang, S-C., et al. (2022). Downregulation of MCF2L Promoted the Ferroptosis of Hepatocellular Carcinoma Cells through PI3K/mTOR Pathway in a RhoA/Rac1 Dependent Manner. Dis Markers doi: 10.1155/2022/6138941 [shRNA vector]
Shrestha, S., et al. (2022). Angiotensin II receptor type 1 blockade regulates Klotho expression to induce TSC2-deficient cell death. J Biol Chem doi: 10.1016/j.jbc.2022.102580 [OMICSLINK™ shRNA clones targeting Agtr1]
Zhu, Y.H., et al. (2022). Apelin‐mediated deamidation of HMGA1 promotes tumorigenesis by enhancing SREBP1 activity and lipid synthesis. Cancer Sci doi: 10.1111/cas.15515 [OmicsLink™ shRNA Clone Collections]
Chen, W.L., et al. (2022). Notch3 Transactivates Glycogen Synthase Kinase-3-Beta and Inhibits Epithelial-to-Mesenchymal Transition in Breast Cancer Cells. Cells doi: 10.3390/cells11182872 [(sh)RNA-GSK3β]
Wang, J-F., et al. (2022). ITGA5 Promotes Tumor Progression through the Activation of the FAK/AKT Signaling Pathway in Human Gastric Cancer. Oxid Med Cell Longev doi: 10.1155/2022/8611306 [ITGA5 silencing and overexpression plasmids]
Xiong, X.F., et al. (2022). FBP1 knockdown decreases ovarian cancer formation and cisplatin resistance through EZH2-mediated H3K27me3. Biosci Rep doi: 10.1042/BSR20221002 [FBP1 shRNA clone]
Schaunaman, N., et a. (2022). Tollip interaction with STAT3: a novel mechanism to regulate human airway epithelial responses to type 2 cytokines. Respiratory Research doi: 10.1186/s12931-022-01941-x [OMICSLINK™ shRNA clone set]
Akel, N., et al. (2022). Loss of chaperone-mediated autophagy is associated with low vertebral cancellous bone mass. Scientific Reports doi: 10.1038/s41598-022-07157-9 [OMICSLINK™ lentiviral shRNA clone set against Lamp2a]
Chen, X., et al. (2022). STAT5A modulates CDYL2/SLC7A6 pathway to inhibit the proliferation and invasion of hepatocellular carcinoma by targeting to mTORC1. Oncogene doi: 10.1038/s41388-022-02273-2 [OMICSLINK™ shRNA clone sets]
Liu, W., et al. (2022). The RBPJ/DAPK3/UBE3A signaling axis induces PBRM1 degradation to modulate the sensitivity of renal cell carcinoma to CDK4/6 inhibitors. Cell Death & Disease doi: 10.1038/s41419-022-04760-6 [OMICSLINK™ shRNA clones]
He, W-P., et al. (2022). Maelstrom promotes tumor metastasis through regulation of FGFR4 and epithelial-mesenchymal transition in epithelial ovarian cancer. Journal of Translational Research doi: 10.1186/s13048-022-00992-4 [OMICSLINK™ lentiviral shRNA clones]
Gu, J., et al. (2022). Hsa-miR-3178/RhoB/PI3K/Akt, a novel signaling pathway regulates ABC transporters to reverse gemcitabine resistance in pancreatic cancer. Molecular Cancer doi: 10.1186/s12943-022-01587-9 [OMICSLINK™ siRNA]
Yi, L., et al. (2022). DNAJA1 Stabilizes EF1A1 to Promote Cell Proliferation and Metastasis of Liver Cancer Mediated by miR-205-5p. Journal of Oncology doi: 10.1155/2022/2292481 [OMICSLINK™ lentiviral shRNA clones targeting DNAJ1]
Alquraishi, M., et al. (2022). Podocyte specific deletion of PKM2 ameliorates LPS-induced podocyte injury through beta-catenin. Cell Communication and Signaling doi: 10.1186/s12964-022-00884-6 [OMICSLINK™ lentiviral shRNA clones targeting PKM2]
Hu, Y., et al. (2022). Neural network learning defines glioblastoma features to be of neural crest perivascular or radial glia lineages. Science Advances doi: 10.1126/sciadv.abm634 [OMICSLINK™ lentiviral shRNA clones]
Liu, Z., et al. (2022). Association between TOP2A, RRM1, HER2, ERCC1 expression and response to chemotherapy in patients with non-muscle invasive bladder cancer. Heliyon doi: 10.1016/j.heliyon.2022.e09643 [OMICSLINK™ lentiviral shRNA clones targeting TOP2]
Harper, M.M., et al. (2022). Interaction of immune checkpoint PD-1 and chemokine receptor 4 (CXCR4) promotes a malignant phenotype in pancreatic cancer cells. PLOS ONE doi: 10.1371/journal.pone.0270832 [OMICSLINK™ shRNA clones targeting PD1]
Ma, W., et al. (2022). Overexpression of LIMA1 Indicates Poor Prognosis and Promotes Epithelial-Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma. Clinical Medicine Insights Oncology doi: 10.1177/11795549221109493 [OMICSLINK™ lentiviral shRNA clones targeting LIMA1]
Li, H-B., et al. (2022). METTL14-mediated epitranscriptome modification of MN1 mRNA promote tumorigenicity and all-trans-retinoic acid resistance in osteosarcoma. eBioMedicine doi: 10.1016/j.ebiom.2022.104142 [OMICSLINK™ lentiviral shRNA clones targeting METTL14]
Chen, C., et al. (2022). GABRP promotes CD44s-mediated gemcitabine resistance in pancreatic cancer. Bioinformatics and Genomics doi: 10.7717/peerj.12728 [OMICSLINK™ shRNA clones targeting CD44]
Guo, T., et al. (2022). RBM47 inhibits hepatocellular carcinoma progression by targeting UPF1 as a DNA/RNA regulator. Cell Death Discovery doi: 10.1038/s41420-022-01112-3 [OMICSLINK™ shRNA clones targeting RBM47]
Hu, X., et al. (2022). DDX24 promotes metastasis by regulating RPL5 in non-small cell lung cancer. Cancer Medicine doi: 10.1002/cam4.4835 [OMICSLINK™ lentiviral shRNA clones targeting DDX24]
Bai, X., et al. (2022). GRHL2 Expression Functions in Breast Cancer Aggressiveness and Could Serve as Prognostic and Diagnostic Biomarker for Breast Cancer. Clinical Medicine Insights: Oncology doi: 10.1177/11795549221109511 [OMICSLINK™ shRNA clones targeting GRHL2]
Wang, Y., et al. (2022). KCTD7 mutations impair the trafficking of lysosomal enzymes through CLN5 accumulation to cause neuronal ceroid lipofuscinoses. Science Advances doi: 10.1126/sciadv.abm5578 [OMICSLINK™ lentiviral shRNA clones targeting KCTD7, CLN5]
Wang, Q., et al. (2022). Post-translational control of beige fat biogenesis by PRDM16 stabilization. Nature doi: 10.1038/s41586-022-05067-4 [OMICSLINK™ lentiviral shRNA clones targeting Cul2, Klhdc2, Lrrc14]

2021

Mao, Y., et al. (2021). Aberrantly up-regulated miR-142-3p inhibited the proliferation and invasion of trophoblast cells by regulating FOXM1. Placenta doi: 10.1016/j.placenta.2021.01.002 [OMICSLINK™ FOXM1 shRNA clone set]
You, L-N., et al. (2021). Exosomal LINC00161 promotes angiogenesis and metastasis via regulating miR-590-3p/ROCK axis in hepatocellular carcinoma. Cancer Gene Therapy doi: 10.1038/s41417-020-00269-2 [OMICSLINK™ LINC00161 shRNA clone set]
Li, L., et al. (2021). TROAP switches DYRK1 activity to drive hepatocellular carcinoma progression. Cell Death & Disease doi: 10.1038/s41419-021-03422-3 [OMICSLINK™ TROAP shRNA clone set]
Woodfield, S.E., et al. (2021). DM4 inhibition: a novel therapeutic strategy to reactivate p53 in hepatoblastoma. Scientific Reports doi: 10.1038/s41598-021-82542-4 [OMICSLINK™ MDM4-35, MDM4-37 lentiviral shRNA clone sets]
Al-Obaide, M.A.I., et al. (2021). Genomic Space ofMGMTin Human Glioma Revisited: NovelMotifs, Regulatory RNAs, NRF1, 2, and CTCF Involvement inGene Expression. International Journal of Molecular Sciences doi: 10.3390/ijms22052492 [OMICSLINK™ CTCF lentiviral shRNA clone set]
Grible, J.M., et al. (2021). The human intermediate prolactin receptor is a mammary proto-oncogene. NPJ Breast Cancer doi: 10.1038/s41523-021-00243-7 [OMICSLINK™ hPRLrI lentiviral shRNA clone set]
Pryszlak, M., et al. (2021). The DEAD-box helicase DDX56 is a conserved stemness regulator in normal and cancer stem cells. Cell Reports doi: 10.1016/j.celrep.2021.108903 [OMICSLINK™ DDX56 shRNA clone set]
Li, J., et al. (2021). Biliverdin Protects Against Cerebral Ischemia/ Reperfusion Injury by Regulating the miR-27a-3p/ Rgs1 Axis. Neuropsychiatric Disease and Treatment 2021:17 1165–1181 [OMICSLINK™ Rgs1 lentiviral shRNA clone set]
Suresh, R. ,et al. (2021). Expression of cell type incongruent alpha-cardiac actin 1 subunit in medulloblastoma reveals a novel mechanism for cancer cell survival and control of migration. Neurooncology Advances [OMICSLINK™ ACTC1 shRNA clone set]
Master, Q.H., et al. (2021). Long Non-Coding RNA CASC2 Overexpression Ameliorates Sepsis-Associated Acute Kidney Injury by Regulating MiR-545-3p/PPARA axis.Joural of Surgical Research doi: 10.1016/j.jss.2021.03.047 [OMICSLINK™ CASC2 shRNA clone set]
Zhang, H., et al. (2021). Exosomal Circ-XIAP Promotes Docetaxel Resistance in Prostate Cancer by Regulating miR-1182/TPD52 Axis. Drug Design, Development and Therapy 2021:15 1835–1849 [OMICSLINK™ XIAP, TDP52 shRNA clone sets]
Ray, U., et al. (2021). Group III phospholipase A2 downregulation attenuated survival and metastasis in ovarian cancer and promotes chemo-sensitization. Journal of Experimental & Clinical Cancer Research doi: 10.1186/s13046-021-01985-9 [OMICSLINK™ PLA23G shRNA clone set]
Li, M., et al. (2021). CircPUM1 promotes cell growth and glycolysisin NSCLC via up-regulating METTL3 expressionthrough miR-590-5p. Cell Cycle doi: 10.1080/15384101.2021.1934625 [OMICSLINK™ circPUM1 lentiviral shRNA clone set]
Zhao, W., et al .(2021). TAFs contributes the function of PTPN2 in colorectal carcinogenesis through activating JAK/STAT signaling pathway. Am J Cancer Res. 2021; 11(6): 3085–3097 [OMICSLINK™ PTPN2 lentiviral shRNA clone set]
Fares, B., et al. (2021). PAX8 plays an essential antiapoptotic role in uterine serous papillary cancer. Oncogene doi: 10.1038/s41388-021-01925-z [OMICSLINK™ PAX8 lentiviral shRNA clone set]
Zhu, H., et al. (2021). Tumorigenic risk of Angelica sinensis on ER-positive breast cancer growth through ER-induced stemness in vitro and in vivo. Journal of Ethnopharmacology doi: 10.1016/j.jep.2021.114415 [OMICSLINK™ ERα shRNA clone set]
Yang, A., et al. (2021). Melatonin inhibits triple-negative breast cancer progression through the Lnc049808-FUNDC1 pathway. Cell Death & Disease doi: 10.1038/s41419-021-04006-x [OMICSLINK™ Lnc049808 and FUNDC1 lentiviral shRNA clone sets]
Ma, C., et al. (2021). HDAC6 inactivates Runx2 promoter to block osteogenesis of bone marrow stromal cells in age-related bone loss of mice. Stem Cell Research and Therapy doi: 10.1186/s13287-021-02545-w [OMICSLINK™ lentiviral shRNA clone sets]
Zhao, S., et al. (2021). CDC20 regulates the cell proliferation and radiosensitivity of P53 mutant HCC cells through the Bcl-2/Bax pathway. International Journal of Biological Sciences doi: 10.7150/ijbs.64003 [OMICSLINK™ CDC20 lentiviral shRNA clone set]
Zhou, X., et al. (2021). Hsa_circ_0004712 downregulation attenuates ovarian cancer malignant development by targeting the miR-331-3p/FZD4 pathway. Journal of Ovarian Research doi: 10.1186/s13048-021-00859-0 [OMICSLINK™ hsa_circ_0004712 lentiviral shRNA clone set]
Liu, B., et al. (2021). CircCDC45 promotes the malignant progression of glioblastoma by modulating the miR-485-5p/CSF-1 axis. BMC Cancer do: 10.1186/s12885-021-08803-7 [OMICSLINK™ circCDC45 lentiviral shRNA clone set]
Meng, Y-M., et al. (2021). Hexokinase 2-driven glycolysis in pericytes activates their contractility leading to tumor blood vessel abnormalities. Nature Communications doi: 10.1038/s41467-021-26259-y [OMICSLINK™ HK2/ROCK1/ROCK2 lentiviral shRNA clone sets]
Marvi, M.V., et al. (2021). Role of PLCγ1 in the modulation of cell migration and cell invasion in glioblastoma. Advances in Biological Regulation doi: 10.1016/j.jbior.2021.100838 [OMICSLINK™ PLCγ1 lentiviral shRNA clone set]
Fan, Q., et al. (2021). Lactobacillus spp. create a protective micro-ecological environment through regulating the core fucosylation of vaginal epithelial cells against cervical cancer. Cell Death & Disease doi: 10.1038/s41419-021-04388-y [OMICSLINK™ Fut8 lentiviral shRNA clone set]
Chen, T., et al. (2021). HIF-1α-activated long non-coding RNA KDM4A-AS1 promotes hepatocellular carcinoma progression via the miR-411-5p/KPNA2/AKT pathway. Cell Death & Disease doi: 10.1038/s41419-021-04449-2 [OMICSLINK™ HIF-1α shRNA clone set]

2020

Luo, C., et al. (2020). lncRNA XIST promotes glioma proliferation and metastasis through miR‑133a/SOX4. Experimental and Therapeutic Medicine doi: 10.3892/etm.2020.8426 [OMICSLINK™ XIST shRNA clone set]
Han, Y., et al. (2020). Remodeling of Zn2+ Homeostasis Upon Differentiation of Mammary Epithelial Cells. Metallomics doi: 10.1039/C9MT00301K [OMICSLINK™ ZIP1 shRNA clone set]
Zhang, J., et al. (2020). Targeting super-enhancer-associated oncogenes in osteosarcoma with THZ2, a covalent CDK7 inhibitor. Clinical Cancer Research doi: 10.1158/1078-0432.CCR-19-1418 [OMICSLINK™ CDK7 lentiviral shRNA clone set]
Jun, F., et al. (2020). Quantitative proteomic analysis identifies novel regulators of methotrexate resistance in choriocarcinoma. Gynecologic Oncology doi: 10.1016/j.ygyno.2020.01.013 [OMICSLINK™ DPP4, METT7LA lentiviral shRNA clone sets]
Hao, S., et al. (2020). Regulation of NKCC2B by TNF-α in response to salt restriction. American Journal of Physiology– Renal Physiology doi: 10.1152/ajprenal.00388.2019 [OMICSLINK™ TNF lentiviral shRNA clone set]
Kanwar, N., et al. (2020). Amplification of a calcium channel subunit CACNG4 increases breast cancer metastasis. EBioMedicine doi: 10.1016/j.ebiom.2020.102646 [OMICSLINK™ CACNG4 lentiviral shRNA clone set]
Budzinska, M.I., et al. (2020). PTPN23 binds the dynein adaptor BICD1 and is required for endocytic sorting of neurotrophin receptors. Journal of Cell Science doi: 10.1242/jcs.242412 [OMICSLINK™ PTPN23 lentiviral shRNA clone set]
Cao, M-Q., et al. (2020). Cross talk between oxidative stress and hypoxia via thioredoxin and HIF-2α drives metastasis of hepatocellular carcinoma. The FASEB Journal doi: 10.1096/fj.202000082R [OMICSLINK™ HIF-2α, TXN lentiviral shRNA clone sets]
Jun, H., et al. (2020). Adrenergic-Independent Signaling via CHRNA2 Regulates Beige Fat Activation. Developmental Cell doi: 10.1016/j.devcel.2020.05.017 [OMICSLINK™ Gabpa lentiviral shRNA clone set]
Thornton, N., et al. (2020). Disruption of the tumour-associated EMP3 enhances erythroid proliferation and causes the MAM-negative phenotype. Nature Communications doi: 10.1038/s41467-020-17060-4 [OMICSLINK™ EMP3 shRNA clone set]
Luo, Y., et al. (2020).MicroRNA-503-3p affects osteogenic differentiation of human adipose-derived stem cells by regulation of Wnt2 and Wnt7b under cyclic strain. Stem Cell Research & Therapy doi: 10.1186/s13287-020-01842-0 [OMICSLINK™ Wnt7b shRNA clone set]
Wang, Y., et al. (2020). The critical role of dysregulated Hh-FOXM1-TPX2 signaling in human hepatocellular carcinoma cell proliferation. Cell Communication and Signaling doi: 10.1186/s12964-020-00628-4 [OMICSLINK™ FOXM1 shRNA clone set]
Yuan, Z., et al. (2020).Exosome-Mediated Transfer of Long Noncoding RNA HOTAIR Regulates Temozolomide Resistance by miR-519a-3p/RRM1 Axis in Glioblastoma. CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS doi: 10.1089/cbr.2019.3499
Li, Y., et al. (2020). Exosomal Circ-ZNF652 Promotes Cell Proliferation, Migration, Invasion and Glycolysis in Hepatocellular Carcinoma via miR-29a-3p/GUCD1 Axis. Cancer Management and Research 12 7739–7751 [OMICSLINK™ circZNF652 shRNA clone set]
Zohud, B.A., et al. (2020). Importin 13 promotes NSCLC progression by mediating RFPL3 nuclear translocation and hTERT expression upregulation. Cell Death & Disease doi: 10.1038/s41419-020-03101-9 [OMICSLINK™ IPO13 lentiviral shRNA clone set]
Chen, Y., et al. (2020). Galactosyltransferase B4GALT1 confers chemoresistance in pancreatic ductal adenocarcinomas by upregulating N-linked glycosylation of CDK11p110. Cancer Letters doi: 10.1016/j.canlet.2020.12.006 [OMICSLINK™ B4GALT1, CDK11 lentiviral shRNA clone sets]
Liu, C., et al. (2020). miR-613 Suppresses Chemoresistance and Stemness in Triple-Negative Breast Cancer by Targeting FAM83A. Cancer Management and Research doi: 10.2147/CMAR.S276316 [OMICSLINK™ FM83A shRNA clone set]
Zhan, Y-T., et al. (2020). SNRPB-mediated RNA splicing drives tumor cell proliferation and stemness in hepatocellular carcinoma. Aging. [OMICSLINK™ SNRPB lentiviral shRNA clone set]

2019

Song, N., et al. (2019). Knockdown of high mobility group box 3 impairs cell viability and colony formation but increases apoptosis in A549 human non‑small cell lung cancer cells. Oncology eports doi: 10.3892/ol.2019.9927 [OMICSLINK™ HMGB lentiviral shRNA clone set]
Jiang, Z., et al. (2019). Rpn10 promotes tumor progression by regulating hypoxia-inducible factor 1 alpha through the PTEN/Akt signaling pathway in hepatocellular carcinoma. Cancer Letters doi: 10.1016/j.canlet.2019.01.020 [OMICSLINK™ Rpn10 lentiviral shRNA clone set]
Chen, Y., et al. (2019). Thermal stress induces glycolytic beige fat formation via a myogenic state. Nature doi:10.1038/s41586-018-0801-z [OMICSLINK™ Gabpa lentiviral shRNA clone set]
Tian, M., et al. (2019). Attractylone attenuates sepsis‐associated encephalopathy and cognitive dysfunction by inhibiting microglial activation and neuroinflammation. Journal of Cellular Biochemistry doi: 10.1002/jcb.27983 [OMICSLINK™ SIRT1 shRNA clone set]
Shen, Y., et al. (2019). Loss-of-function mutations in QRICH2 cause male infertility with multiple morphological abnormalities of the sperm flagella. Nature Communications doi:10.1038/s41467-018-08182-x [OMICSLINK™ QRICH2 lentiviral shRNA clone set]
Zhou, X., et al. (2019). Metformin Inhibit Lung Cancer Cell Growth and Invasion in Vitro as Well as Tumor Formation in Vivo Partially by Activating PP2A. Medical Science Monitor doi: 10.12659/MSM.912059 [OMICSLINK™ lentiviral shRNA clone sets]
Yan, S-P., et al. (2019). LncRNA LINC01305 silencing inhibits cell epithelial‐ mesenchymal transition in cervical cancer by inhibiting TNXB‐mediated PI3K/Akt signalling pathway. Journal of Cellular and Molecular Medicine doi: 10.1111/jcmm.1 [OMICSLINK™ LINC01305 shRNA clone set]
Chen, X., et al. (2019). Monocarboxylate transporter 1 is an independent prognostic factor in esophageal squamous cell carcinoma. Oncology Reports doi: 10.3892/or.2019.6992 [OMICSLINK™ MCT1 shRNA clone set]
Li, Y., et al. (2019). CHD1L contributes to cisplatin resistance by upregulating the ABCB1–NF-κB axis in human non-small-cell lung cancer. cell Death & Disease doi: 10.1038/s41419-019-1371-1 [OMICSLINK™ CHD1L shRNA clone set]
Wen, Y., et al. (2019). RPS7 promotes cell migration through targeting epithelial-mesenchymal transition in prostate cancer. Urologic Oncology: Seminars and Original Investigations doi: 10.1016/j.urolonc.2019.01.011 [OMICSLINK™ RPS7 shRNA clone set]
Liu, Y-N., et al. (2019). Sphingosine 1 phosphate receptor-1 (S1P1) promotes tumor-associated regulatory T cell expansion: leading to poor survival in bladder cancer. Cell Death & Disease doi: 10.1038/s41419-018-1298-y [OMICSLINK™ SIP1 lentiviral shRNA clone set]
Jiao, J-X., et al. (2019). Knockdown of aristaless-like homeobox1 inhibits epithelial-mesenchymal transition through Wnt/β-catenin signaling pathway in melanoma cells. Biochemical and Biophysical Research Communications doi: 10.1016/j.bbrc.2019.02.050 [OMICSLINK™ ALX1 lentiviral shRNA clone set]
Wei, F., et al. (2019). PD-L1 promotes colorectal cancer stem cell expansion by activating HMGA1-dependent signaling pathways. Cancer Letters doi: 10.1016/j.canlet.2019.02.022 [OMICSLINK™ HMGA1 lentiviral shRNA clone set]
Wu, H-Y., et al. (2019). Deletion of Dicer blocks osteogenic differentiation via the inhibition of Wnt signalling. Molecular Medicine Reports doi: 10.3892/mmr.2019.9941 [OMICSLINK™ Dicer 1 lentiviral shRNA clone set]
Yao, X., et al. (2019). miR-99b-3p promotes hepatocellular carcinoma metastasis and proliferation by targeting protocadherin 19. Gene doi: 10.1016/j.gene.2019.02.071 [OMICSLINK™ PTPRT shRNA clone set]
Guan, C., et al. (2019). MMP-12 regulates proliferation of mouse macrophages via the ERK/P38 MAPK pathways during inflammation. Experimental Cell Research doi: 10.1016/j.yexcr.2019.03.018 [OMICSLINK™ MMP12-1, MMP12-2 lentiviral shRNA clone sets]
Dakhama, A., et al. (2019). Tollip Inhibits ST2 Signaling in Airway Epithelial Cells Exposed to Type 2 Cytokines and Rhinovirus. Journal of Innate Immunity doi: 10.1159/000497072 [OMICSLINK™ Tollp, IRAK1 lentiviral shRNA clone sets]
Li, X., et al. (2019). Overexpression of CEP72 Promotes Bladder Urothelial Carcinoma Cell Aggressiveness via Epigenetic CREB-Mediated Induction of SERPINE1. The American Journal of Patholgy doi: 10.1016/j.ajpath.2019.02.014 [OMICSLINK™ lentiviral shRNA clone set]
Ma, Q., et al. (2019). ENKUR Is Involved in the Regulationof Cellular Biology in Colorectal CancerCells via PI3K/Akt Signaling Pathway. Technology in Cancer Research & Treatment doi: 10.1177/1533033819841433 [OMICSLINK™ lentiviral shRNA clone set targeting EUNKUR]
Su, Q., et al. (2019). Impaired Tip60-mediated Foxp3 acetylation attenuates regulatory T cell development in rheumatoid arthritis. Journal of Autoimmunity doi: 10.1016/j.jaut.2019.02.007 [OMICSLINK™ lentiviral shRNA clone set targeting Tip60]
Liu, A-G., et al. (2019). Down-regulation of MRPS23 inhibits LPS-induced proliferation and invasion via regulation of the NF-κB signaling pathway in osteosarcoma cells. RSC Advances doi: 10.1039/C8RA08973F [OMICSLINK™ lentiviral shRNA clone set targeting MRPS23]
Tarantini, S., et al. (2019). Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice. Redox Biology doi: 10.1016/j.redox.2019.101192 [OMICSLINK™ shRNA clone sets targeting SIRT1, SIRT2]
Zhu, H., et al. (2019). ALKBH5 inhibited autophagy of epithelial ovarian cancer through miR-7 and BCL-2. Journal of Experimental & Clinical Cancer Research doi: 10.1186/s13046-019-1159-2 [OMICSLINK™ ALKBH5 lentiviral shRNA expression clone]
Zhang, J-X, et al. (2019). A positive feedback loop consisting of C12orf59/NF-κB/CDH11 promotes gastric cancer invasion and metastasis. Journal of Experimental & Clinical Cancer Research doi: 10.1186/s13046-019-1114-2 [OMICSLINK™ p65, C12orf59 shRNA expression clones]
Sun, W., et al. (2019). MicroRNA-3648 Is Upregulated to Suppress TCF21, Resulting in Promotion of Invasion and Metastasis of Human Bladder Cancer. Molecular Thereapy Nucleic Acids doi: 10.1016/j.omtn.2019.04.006 [OMICSLINK™ shRNA clone set targeting TCF21]
Zhu, J., et al. (2019). MicroRNA-146b Overexpression Promotes Human Bladder Cancer Invasion via Enhancing ETS2-Mediated mmp2 mRNA Transcription. Molecular Thereapy Nucleic Acids doi: 10.1016/j.omtn.2019.04.007 [OMICSLINK™ shRNA clone set targeting AUF1]
Li, Z., et al. (2019). Mitochondrial TRPC3 promotes cell proliferation by regulating the mitochondrial calcium and metabolism in renal polycystin-2 knockdown cells. International Urology and Nephrology10.1007/s11255-019-02149-7 [OMICSLINK™ shRNA clone sets targeting TRPP2, TRPC3]
Soni, S., et al. (2019). MAPKAPK2 plays a crucial role in the progression of head and neck squamous cell carcinoma by regulating transcript stability. Journal of Experimental & Clinical Cancer Research doi: 10.1186/s13046-019-1167-2 [OMICSLINK™ shRNA clone set targeting MK2]
Levels, M.J., et al. (2019). BOB.1 controls memory B-cell fate in the germinal center reaction. Journal of Autoimmunity doi: 10.1016/j.jaut.2019.04.011 [OMICSLINK™ lentiviral shRNA clone set targeting BOB.1]
Hu, X., et al. (2019). Preoperative plasma IGFBP2 is associated with nodal metastasis in patients with penile squamous cell carcinoma. Urologic Oncology: Seminars and Original Investigations doi: 10.1016/j.urolonc.2019.04.013 [OMICSLINK™ lentiviral shRNA clone set targeting IGFBP2]
Zhang, K., et al. (2019). ALK5 signaling pathway mediates neurogenesis and functional recovery after cerebral ischemia/reperfusion in rats via Gadd45b. Cell Deth & Disease doi: 10.1038/s41419-019-1596-z [OMICSLINK™ lentiviral shRNA clone set targeting ALK5]
Zhao, Q., et al. (2019). Bisphenol AF promotes estrogen receptor-positive breast cancer cell proliferation through amphiregulin-mediated crosstalk with receptor tyrosine kinase signaling. PLOS ONE doi: 10.1371/journal.pone.0216469 [OMICSLINK™ lentiviral shRNA clone set targeting AREG]
Zheng, H., et al. (2019). Carboxypeptidase A4 promotes proliferation and stem cell characteristics of hepatocellular carcinoma. Inernational Journal of Experimental Pathology doi: 10.1111/iep.12315 [OMICSLINK™ CPA4 lentiviral ORF expression clone; OMICSLINK™ lentiviral shRNA clone set targeting CPA4]
Wang, J., et al. (2019). Low expression of ACLY associates with favorable prognosis in acute myeloid leukemia. Journal of Translational Medicine doi: 10.1186/s12967-019-1884-5 [OMICSLINK™ lentiviral shRNA clone set targeting ACLY]
Jia, Y., et al. (2019). Phosphorylation of 14-3-3ζ links YAP transcriptional activation to hypoxic glycolysis for tumorigenesis. Oncogenesis doi:10.1038/s41389-019-0143-1 [OMICSLINK™ lentiviral shRNA clone set targeting YAP1]
Li, D., et al. (2019). LOC103691336/miR‐138‐5p/BMPR2 axis modulates Mg‐mediated osteogenic differentiation in rat femoral fracture model and rat primary bone marrow stromal cells. Journal of Cellular Physiology doi: 10.1002/jcp.28736 [OMICSLINK™ shRNA clone set]
Jiang, Q., et al. (2019). Resveratrol regulates skeletal muscle fibers switching through the AdipoR1-AMPK-PGC-1α pathway. Food Function doi: 10.1039/C8FO02518E [OMICSLINK™ shRNA clone sets for AdopoR1 and AdipoR2]
Xiao, W., and Yin, A. (2019). LINC0638 lncRNA is involved in the local recurrence of melanoma following surgical resection. Oncology Letters doi: 10.3892/ol.2019.10322 [OMICSLINK™ shRNA clones targeting LINC01638]
Liu, P., et al. (2020). Melatonin Regulates Breast Cancer Progressionby the lnc010561/miR-30/FKBP3 Axis. Molecular Therapy-Nucleic Acids doi: 10.1016/j.omtn.2019.12.019 [OMICSLINK™ lentiviral shRNA clones targeting FKBP3 and lnc010561]
Ni, Z., et al. (2019). The exosome-like vesicles from osteoarthritic chondrocyte enhanced mature IL-1β production of macrophages and aggravated synovitis in osteoarthritis. Cell Death & Disease doi: 10.1038/s41419-019-1739-2 [OMICSLINK™ lentiviral shRNA clone set targeting ATGA4]
Chen, X., et al. (2019). 5-methylcytosine promotes pathogenesis of bladder cancer through stabilizing mRNAs. Nature Cell Biology doi: 10.1038/s41556-019-0361-y [OMICSLINK™ lentiviral shRNA clone set]
Yoneshiro, T., et al. (2019). BCAA catabolism in brown fat controls energy homeostasis through SLC25A44. Nature doi: 10.1038/s41586-019-1503-x [OMICSLINK™ lentiviral shRNA clone set targeting Slc25a44]

2018

Yang, G., et al. (2018). The TET2/E-cadherin/β-catenin regulatory loop confers growth and invasion in hepatocellular carcinoma cells. Experimental Cell Research doi: 10.1016/j.yexcr.2018.01.011 [OMICSLINK™ TET2 and β-catenin shRNA clone sets]
Hosaka, K., et al. (2018). Dual roles of endothelial FGF-2–FGFR1–PDGF-BB and perivascular FGF-2–FGFR2–PDGFRβ signaling pathways in tumor vascular remodeling. Cell Discovery doi: 10.1038/s41421-017-0002-1 [OMICSLINK™ Fgf2 lentiviral shRNA clone set]
Ghannam-Shahbari, D., et al. (2018). PAX8 activates a p53-p21-dependent pro-proliferative effect in high grade serous ovarian carcinoma. Oncogene doi: 10.1038/s41388-017-0040-z [OMICSLINK™ PAX8 shRNA clone set]
Wang, C., et al. (2018). Histone Methyltransferase Setd7 Regulates Nrf2 Signaling Pathway by Phenethyl Isothiocyanate and Ursolic Acid in Human Prostate Cancer Cells. doi: 10.1002/mnfr.201700840 [OMICSLINK™ shRNA clone set]
Jaafar, R., et al. (2018). RIP2 enhances cell survival by activation of NF-ĸB in triple negative breast cancer cells. Biochemical and Biophysical Research Communications doi: 10.1016/j.bbrc.2018.02.034 [OMICSLINK™ RIP2 shRNA clone set]
Chen, R., et al. (2018). High and low doses of cocaine intake are differentially regulated by dopamine D2 receptors in the ventral tegmental area and the nucleus accumbens. Neuroscience Letters doi: 10.1016/j.neulet.2018.02.026 [OMICSLINK™ shRNA clone set]
Li, N., et al. (2018). The role of BKCa in endometrial cancer HEC-1-B cell proliferation and migration. Gene doi: 10.1016/j.gene.2018.02.055 [OMICSLINK™ BKCa lentiviral shRNA clone set]
Mikhaylova, M., et al. (2018). Caldendrin Directly Couples Postsynaptic Calcium Signals to Actin Remodeling in Dendritic Spines. Neuron doi: 10.1016/j.neuron.2018.01.046 [OMICSLINK™ caldherin shRNA clone set]
Zhang, J-X., et al. (2018). LINC01410-miR-532-NCF2-NF-kB feedback loop promotes gastric cancer angiogenesis and metastasis. Oncogene doi: 10.1038/s41388-018-0162-y [OMICSLINK™ LINC01410 shRNA clone set]
Federer‐Gsponer, J.R., et al. (2018). Delineation of human prostate cancer evolution identifies chromothripsis as a polyclonal event and FKBP4 as a potential driver of castration resistance. The Journal of Pathology doi: 10.1002/path.5052 [OMICSLINK™ FKBP4 shRNA clone set]
Li, C., et al. (2018). Long non-coding RNA KCNQ1OT1 mediates the growth of hepatocellular carcinoma by functioning as a competing endogenous RNA of miR-504. International Journal of Oncology doi: 10.3892/ijo.2018.4313 [OMICSLINK™ KCNQ1OT1 shRNA clone set]
Zhang, J., et al. (2018). Upregulation of miR-614 promotes proliferation and inhibits apoptosis in ovarian cancer by suppressing PPP2R2A expression. Molecular Medicine Reports doi: 10.3892/mmr.2018.8714 [OMICSLINK™ PPP2R2A shRNA clone set]
Lupia, M., et al. (2018). CD73 Regulates Stemness and Epithelial-Mesenchymal Transition in Ovarian Cancer-Initiating Cells. Stem CEll Reports doi: 10.1016/j.stemcr.2018.02.009 [OMICSLINK™ CD73 shRNA clone set]
Yin, J., et al. (2018). Amyloid-β Increases Tau by Mediating Sirtuin 3 in Alzheimer’s Disease. Molecular Neurobiology doi: 10.1007/s12035-018-0977-0 [OMICSLINK™ Sirt3 shRNA clone set]
Guo, F., et al. (2018). Decreased PECAM1-mediated TGF-β1 expression in the mid-secretory endometrium in women with recurrent implantation failure . Human Reproduction doi: 10.1093/humrep/dey022 [OMICSLINK™ PECAM1 shRNA clone set]
Zhang, B., et al. (2018). TSPAN15 interacts with BTRC to promote oesophageal squamous cell carcinoma metastasis via activating NF-κB signaling. Nature Communications doi: 10.1038/s41467-018-03716-9 [OMICSLINK™ TSPAN15 lentiviral shRNA clone set]
Wang, Y., et al. (2018). TP53INP1 inhibits hypoxia‐induced vasculogenic mimicry formation via the ROS/snail signalling axis in breast cancer. Journal of Cellular and Molecular Medicine doi: 10.1111/jcmm.13625 [OMICSLINK™ CXCR2, CXCl5 lentiviral shRNA clone sets]
Johnson, J., et al. (2018). Fank1 and Jazf1 promote multiciliated cell differentiation in the mouse airway epithelium. Biology Open doi: 10.1242/bio.033944 [OMICSLINK™ Fank1, Jazf1 lentiviral shRNA clone sets]
Wu, X., et al. (2018). Interleukin-6 from subchondral bone mesenchymal stem cells contributes to the pathological phenotypes of experimental osteoarthritis. Am J Transl Res 2018;10(4):1143-1154 [OMICSLINK™ IL-6 lentiviral shRNA clone set]
Yang, Z., et al. (2018). Knockdown of TNF‑α alleviates acute lung injury in rats with intestinal ischemia and reperfusion injury by upregulating IL‑10 expression. International Journal of Molecular Medicine doi: 10.3892/ijmm.2018.3674 [OMICSLINK™ TNF‑α lentiviral shRNA clone set]
Gu, Z., et al. (2018). LncRNA DICER1-AS1 promotes the proliferation, invasion and autophagy of osteosarcoma cells via miR-30b/ATG5. Biomedicine & Pharmacotherapy doi: 10.1016/j.biopha.2018.04.193 [OMICSLINK™ DICER1-AS1 shRNA clone set]
Li, X., et al. (2018). Sulfiredoxin-1 enhances cardiac progenitor cell survival against oxidative stress via the upregulation of the ERK/NRF2 signal pathway. Free Radical Biology and Medicine doi: 10.1016/j.freeradbiomed.2018.05.060 [OMICSLINK™ SRXN1 lentiviral shRNA clone set]
Talukdar, S., et al. (2018). MDA-9/Syntenin regulates protective autophagy in anoikis-resistant glioma stem cells. Proceedings of the National Academy of Sciences of the United States of America doi: 10.1073/pnas.1721650115 [OMICSLINK™ PKC-α lentiviral shRNA clone set]
Porello, A., et al. (2018). Factor XIIIA—expressing inflammatory monocytes promote lung squamous cancer through fibrin cross-linking. Nature Communications doi: 10.1038/s41467-018-04355-w [OMICSLINK™ CCL2 lentiviral shRNA clone set]
Liu, F., et al. (2018). MicroRNA‑433 reduces cell proliferation and invasion in non‑small cell lung cancer via directly targeting E2F transcription factor 3. Molecular Medicine Reports doi: 10.3892/mmr.2018.9020 [OMICSLINK™ E2F3 shRNA clone set]
Chen, L., et al. (2018). Co-delivery of doxorubicin and shRNA of Beclin1 by folate receptor targeted pullulan-based multifunctional nanomicelles for combinational cancer therapy. RSC Advances doi: 10.1039/C8RA01679H [OMICSLINK™ Becelin 1 shRNA clone set]
Gibbs, K.L., et al. (2018). Inhibiting p38 MAPK alpha rescues axonal retrograde transport defects in a mouse model of ALS. Cell Death & Disease doi: 10.1038/s41419-018-0624-8 [OMICSLINK™ p38 MAPKα lentiviral shRNA clone set]
Liu, H., et al. (2018). Triptolide inhibits vascular endothelial growth factor‑mediated angiogenesis in human breast cancer cells. Experimental and Therapeutic Medicine doi: 10.3892/etm.2018.6200 [OMICSLINK™ HIF1‑α, VEGFA sgRNA clone sets]
Anderson, C.J., et al. (2018). Prohibitin is a positive modulator of mitochondrial function in PC12 cells under oxidative stress. Journal of Neurochemistry doi: 10.1111/jnc.14472 [OMICSLINK™ rat PHB sgRNA clone set]
Qian, H., et al. (2018). The lncRNA MIR4435-2HG promotes lung cancer progression by activating β-catenin signalling. Journal of Molecular Medicine doi: 10.1007/s00109-018-1654-5 [OMICSLINK™ MIR4435-2HG lentiviral shRNA clone set]
Yang, D., et al. (2018). Utilization of adipocyte-derived lipids and enhanced intracellular trafficking of fatty acids contribute to breast cancer progression. Cell Communication and Signaling doi: 10.1186/s12964-018-0221-6 [OMICSLINK™ ATGL lentiviral shRNA clone set]
Teng, j., et al. (2018). Down-regulation of GRP78 alleviates lipopolysaccharide-induced acute kidney injury. International Urology and Nephrology doi: 10.1007/s11255-018-1911-0 [siRNA against GRP78]
Bai, P-s., et al. (2018). Hepatitis B virus promotes proliferation and metastasis in male Chinese hepatocellular carcinoma patients through the LEF-1/miR-371a-5p/SRCIN1/pleiotrophin/Slug pathway. Experimental Cell Research doi: 10.1016/j.yexcr.2018.06.020 [OMICSLINK™ LEF-1, SRCIN1 and PTN shRNA clone sets]
Liu, F., et al. (2018). miR‑124‑3p acts as a potential marker and suppresses tumor growth in gastric cancer. Biomedical Reports doi: 10.3892/br.2018.1113 [OMICSLINK™ SP1, Rac1 shRNA clone sets]
Estrada, C.C., et al. (2018). Krüppel-like factor 4 is a negative regulator of STAT3-induced glomerular epithelial cell proliferation. JCI Insight doi: 10.1172/jci.insight.98214 [OMICSLINK™ KLF4 lentiviral shRNA clone set]
Zhang, M., et al. (2018). Thymoquinone induces apoptosis in bladder cancer cell via endoplasmic reticulum stress-dependent mitochondrial pathway. Chemico-Biological Interactions doi: 10.1016/j.cbi.2018.06.013 [OMICSLINK™ CHOP lentiviral shRNA clone set]
Qian, K., et al. (2018). Overexpression of Salusin-α Inhibits Vascular Intimal Hyperplasia in an Atherosclerotic Rabbit Model. BioMed Research International doi: 10.1155/2018/8973986 [OMICSLINK™ salusin-α lentiviral shRNA clone set]
Liu, Z., et al. (2018). Gli2 Mediated Activation of Hedgehog Signaling Attenuates Acute Pancreatitis via Balancing Inflammatory Cytokines in Mice. Cellular Physiology and Biochemistry doi: 10.1159/000491668 [OMICSLINK™ Gli2 shRNA clone set]
Luo, L., et al. (2018). LINC01638 lncRNA activates MTDH-Twist1 signaling by preventing SPOP-mediated c-Myc degradation in triple-negative breast cancer. Oncogene doi: 10.1038/s41388-018-0396-8 [OMICSLINK™ shRNA clone sets for LINC01638, MTDH, SPOP and c-Myc]
Xiao, S., et al. (2018). Anti-inflammatory effect of hesperidin enhances chondrogenesis of human mesenchymal stem cells for cartilage tissue repair. Journal of Inflammation doi: 10.1186/s12950-018-0190-y [OMICSLINK™ lentiviral shRNA clone set for p65]
Chen, J., et al. (2018). Serum- and glucocorticoid-inducible kinase 3 is a potential oncogene in nasopharyngeal carcinomaQuinase 3 sérica induzida por glicocorticoide é um potencial oncogene no carcinoma nasofaríngeo. Brazilian Journal of Otorhinolaryngology doi: 10.1016/j.bjorl.2018.05.012 [OMICSLINK™ shRNA clone set for SGK3]
Huang, X., et al. (2018). Adam12 and lnc015192 act as ceRNAs in breast cancer by regulating miR-34a. Oncogene doi: 10.1038/s41388-018-0410-1 [OMICSLINK™ shRNA clone sets for Adam12 and lnc015192]
Le, Q., et al. (2018). Role of OCT4 in cisplatin treatment of testicular embryonal carcinoma. Tropical Journal of Pharmaceutic al Research doi: 10.4314/tjpr.v1 [OMICSLINK™ shRNA clone set for Oct4]
Bacq, A., et al. (2018). Amygdala GluN2B-NMDAR dysfunction is critical in abnormal aggression of neurodevelopmental origin induced by St8sia2 deficiency. Molecular Psychiatry doi: 10.1038/s41380-018-0132-3 [OMICSLINK™ shRNA clone set for St8sai2]
Mo, M-S., et al. )2018). Dopaminergic neurons show increased low-molecular-mass protein 7 activity induced by 6-hydroxydopamine in vitro and in vivo. Translational Neurodegeneration doi: 10.1186/s40035-018-0125-9 [OMICSLINK™ shRNA clone set for β5i]
Niculescu, D., et al. (2018). A BDNF-Mediated Push-Pull Plasticity Mechanism for Synaptic Clustering. Cell Reports doi: 10.1016/j.celrep.2018.07.073 [OMICSLINK™ shRNA clone set for BDNF]
Ni, B., et al. (2018). Hydroxysafflor yellow A protects against angiotensin II‑induced hypertrophy. Molecular Medicine Reports doi: 10.3892/mmr.2018.9399 [OMICSLINK™ shRNA clone set for Nrf2]
Liu, Z., et al. (2018). Silencing FOXC1 inhibits growth and migration of human oral squamous cell carcinoma cells. Experimental and Therepaeutic Medicine doi: 10.3892/etm.2018.6627 [OMICSLINK™ lentiviral shRNA clone set for FOX1C]
Bai, X-Z., et al. (2018). MicroRNA-138 Aggravates Inflammatory Responses of Macrophages by Targeting SIRT1 and Regulating the NF-κB and AKT Pathways. Cellular Physiology and Biochemistry doi: 10.1159/000492988 [OMICSLINK™ shRNA clone set for SIRT1]
Cao, S., et al. (2018). FOXC1 induces cancer stem cell-like properties through upregulation of beta-catenin in NSCLC. Journal of Experimental & Clinical Cancer Research doi: 10.1186/s13046-018-0894-0 [OMICSLINK™ shRNA clone set for FOXC1]
Xie, X., et al. (2018). Long non‑coding RNA, CHRF, predicts poor prognosis of lung adenocarcinoma and promotes cell proliferation and migration. Oncology Letters doi: 10.3892/ol.2018.9425 [OMICSLINK™ shRNA clone set for CHRF]
Cao, L., et al. (2018). AR–PDEF pathway promotes tumour proliferation and upregulates MYC-mediated gene transcription by promoting MAD1 degradation in ER-negative breast cancer. Molecular Cancer doi: 10.1186/s12943-018-0883-0 [OMICSLINK™ lentiviral shRNA clone sets for PDEF, AR]
Zhang, J., et al. (2018). LGR5, a novel functional glioma stem cell marker, promotes EMT by activating the Wnt/β-catenin pathway and predicts poor survival of glioma patients. Journal of Experimental & Clinical Cancer Research doi: 10.1186/s13046-018-0864-6 [OMICSLINK™ shRNA clone set for LGR5]
Zhou, Z., et al. (2018). Down-regulation of Rab10 inhibits hypoxia-induced invasion and EMT in thyroid cancer cells by targeting HIF-1α through the PI3K/Akt pathway. RSC Advances doi: 10.1039/C8RA05855E [OMICSLINK™ shRNA clone set for HIF-1α]
Franco, R., et al. (2018). N-Methyl-D-Aspartate Receptor Link to the MAP Kinase Pathway in Cortical and Hippocampal Neurons and Microglia Is Dependent on Calcium Sensors and Is Blocked by α-Synuclein, Tau, and Phospho-Tau in Non-transgenic and Transgenic APPSw,Ind Mice. Frontiers in Molecular Neuroscience doi: 10.3389/fnmol.2018.00273 [OMICSLINK™ shRNA clone sets for NCS1, CaM, or calneuron-1]
Liu, P., et al. (2018). PNMA1, regulated by miR-33a-5p, promotes proliferation and EMT in hepatocellular carcinoma by activating the Wnt/β-catenin pathway. Biomedicine & Pharmacotherapy doi: 10.1016/j.biopha.2018.09.059 [OMICSLINK™ lentiviral shRNA clone set for PNMA1]
Mendez, C., et al. (2018). RNA-induced epigenetic silencing inhibits HIV-1 reactivation from latency. Retrovirology doi: 10.1186/s12977-018-0451-0 [OMICSLINK™ lentiviral shRNA clone set]
Barth, A.I., et al. (2018). Regulation of epithelial migration by epithelial cell adhesion molecule requires its Claudin-7 interaction domain. PLOS One doi: 10.1371/journal.pone.0204957 [OMICSLINK™ shRNA clone set for EpCAM]
Jia, C., et al. (2018). MicroRNA‑466 inhibits the aggressive behaviors of hepatocellular carcinoma by directly targeting metadherin. Oncology Reports doi: 10.3892/or.2018.6763 [OMICSLINK™ shRNA clone set for MTDH]
Liu, S-Y., et al. (2018). Resveratrol protects photoreceptors by blocking caspase- and PARP-dependent cell death pathways. Free Radical Biology and Medicine doi: 10.1016/j.freeradbiomed.2018.10.4313 [OMICSLINK™ shRNA clone set for PARP1]
Gupta, P., et al. (2018). HER2-mediated GLI2 stabilization promotes anoikis resistance and metastasis of breast cancer cells. Cancer Letters doi: 10.1016/j.canlet.2018.10.021 [OMICSLINK™ lentiviral shRNA clone set for GLI2]
Zhao, Y., et al. (2018). BPTF promotes hepatocellular carcinoma growth by modulating hTERT signaling and cancer stem cell traits. Redox Biology doi: 10.1016/j.redox.2018.10.018 [OMICSLINK™ shRNA clone set for BPTF]
Strassel, C., et al. (2018). Microtubule plus-end tracking Adenopolyposis Coli negatively regulates proplatelet formation. Scientific Reports doi: 10.1038/s41598-018-34118-y [OMICSLINK™ lentiviral shRNA clone set for APC]
Gao, M., et al. (2018). Direct therapeutic targeting of immune checkpoint PD-1 in pancreatic cancer. British Journal of Cancer doi: 10.1038/s41416-018-0298-0 [OMICSLINK™ shRNA clone set for PD1]
Wang, Y., et al. (2018). miR-532-3p promotes hepatocellular carcinoma progression by targeting PTPRT. Biomedicine & Pharmacotherapy doi: 10.1016/j.biopha.2018.10.145 [OMICSLINK™ lentiviral shRNA clones set for PTPRT]
Wang, C., et al. (2018). Transcriptomic Analysis of Histone Methyltransferase Setd7 Knockdown and Phenethyl Isothiocyanate in Human Prostate Cancer Cells. Anticancer Research doi: 10.21873/anticanres.12957 [OMICSLINK™ lentiviral shRNA clone set for SETD7]
D’Costa, S., et al. (2018). Mast Cell CRF2 Suppresses Mast Cell Degranulation and Limits the Severity of Anaphylaxis and Stress-Induced Intestinal Permeability. Journal of Allergy and Clinical Immunology doi: 10.1016/j.jaci.2018.08.053 [OMICSLINK™ lentiviral shRNA clone set for CRF2]
Xie, X-W., et al,. (2018). Effect of Upregulated DNA Replication and Sister Chromatid Cohesion 1 Expression on Proliferation and Prognosis in Hepatocellular Carcinoma. Chinse Medical Journal doi: 10.4103/0366-6999.246076 [OMICSLINK™ lentiviral shRNA clone set for DCC1]
Shao, B., et al. (2018). LOXL2 promotes vasculogenic mimicry and tumour aggressiveness in hepatocellular carcinoma. Journal of Cellular and Molecular Medicine doi: 10.1111/jcmm.140 [OMICSLINK™ lentiviral shRNA clone set for Twist1]
Lim, V., et al. (2018). PKP3 interactions with MAPK-JNK-ERK1/2-mTOR pathway regulates autophagy and invasion in ovarian cancer. Biochemical and Biophysical Research Communications doi:10.1016/j.bbrc.2018.11.163 [OMICSLINK™ lentiviral shRNA clone set for PKP3]
Zhou, R., et al. (2018). Resveratrol Ameliorates Lipid Droplet Accumulation in Liver Through a SIRT1/ ATF6-Dependent Mechanism. Cellular Physiology and Biochemistry doi: 10.1159/000495898 [OMICSLINK™ lentiviral shRNA clone set for ATF6]
Xao, S., et al. (2018). MiR‐34c/SOX9 axis regulates the chemoresistance of ovarian cancer cell to cisplatin‐based chemotherapy. Journal of Cellular Biochemistry doi: 10.1002/jcb.26865 [OMICSLINK™ lentiviral shRNA clone set for SOX9]
Guo, X., et al. (2018). LncRNA MALAT1 protects cardiomyocytes from isoproterenol‐induced apoptosis through sponging miR‐558 to enhance ULK1‐mediated protective autophagy. Journal of CEllular Physiology doi: 10.1002/jcp.27925 [OMICSLINK™ lentiviral shRNA clone sets for MALAT1, ULK1]
Qian, W., et al. (2018). Knockdown of long non-coding RNA TUG1 suppresses nasopharyngeal carcinoma progression by inhibiting epithelial-mesenchymal transition (EMT) via the promotion of miR-384.Biochemical and Biophysical Research Communications doi: 10.1016/j.bbrc.2018.12.011 [OMICSLINK™ shRNA clone set for TUG1]
Dalley, C.B., etal. (2018). The Role of Metabotropic Glutamate Receptor 1 Dependent Signaling in Glioma V iability. JPET Fast Forward doi: 10.1124/jpet.118.250159 [OMICSLINK™ shRNA clone sets]

2017

Huang, C., et al. (2017). XIAP BIR domain suppresses miR-200a expression and subsequently promotes EGFR protein translation and anchorage-independent growth of bladder cancer cell. Journal of Hematology and Oncology doi: 10.1186/s13045-016-0376-9 [mir200a shRNA clone set]
Gao. L., et al. (2017). FGF19/FGFR4 signaling contributes to the resistance of hepatocellular carcinoma to sorafenib. Journal of Experimental & Clinical Cancer Research doi: 10.1186/s13046-016-0478-9 [FGF19 shRNA clone set]
Mak, C.S.L., et al. (2017). MicroRNA-141 enhances anoikis resistance in metastatic progression of ovarian cancer through targeting KLF12/Sp1/survivin axis. Molecular Cancer doi: 10.1186/s12943-017-0582-2 [KLF12 shRNA clone set]
Haile, Y., et al. (2017). Rab32 connects ER stress to mitochondrial defects in multiple sclerosis. Journal of Neuroinflammation doi: 10.1186/s12974-016-0788-z [OMICSLINK™ Rab32 shRNA clone set]
Popovics, P., et al. (2017). Antagonists of growth hormone-releasing hormone inhibit proliferation induced by inflammation in prostatic epithelial cells. Proceedings of the National Academy of Sciences of the U.S.A. doi: 10.1073/pnas.1620884114 [OMICSLINK™ GHRHR1 and GHRHR2 shRNA clone sets]
Jin, L., et al. (2017). Three novel ANO5 missense mutations in Caucasian and Chinese families and sporadic cases with gnathodiaphyseal dysplasia. Scientific Reports doi: 10.1038/srep40935 [OMICSLINK™ LVRH1 shRNA clone set]
Schaaf, K., et al. (2017). Mycobacterium tuberculosis exploits the PPM1A signaling pathway to block host macrophage apoptosis. Scientific Reports doi: 10.1038/srep42101 [OMICSLINK™ PPM1A shRNA clone set]
Li, J., et al. (2017). Knockdown of IL-8 Provoked Premature Senescence of Placenta-Derived Mesenchymal Stem Cells. Stem Cells and Development doi: 10.1089/scd.2016.0324 [OMICSLINK™ IL8 shRNA lentiviral clone set]
Foy, M., et al. (2017). PRL-3/PTP4A3 phosphatase regulates integrin β1 in adhesion structures during migration of human ocular melanoma cells. Experimental Cell Research doi: 0.1016/j.yexcr.2017.03.012 [OMICSLINK™ ITGB1 shRNA clone set]
Sasaki, K., etal. (2017). Genome-wide in vivo RNAi screen identifies ITIH5 as a metastasis suppressor in pancreatic cancer. Clinical & Experimental Metastasis doi: 10.1007/s10585-017-9840-3 [OMICSLINK™ ITIH5 shRNA clone set]
Li, K., et al. (2017). ELF5-Mediated AR Activation Regulates Prostate Cancer Progression. Scientific Reports doi: 10.1038/srep42759 [OMICSLINK™ ELF5 shRNA clone set]
Sun, J., et al. (2017). HMGA2 regulates CD44 expression to promote gastric cancer cell motility and sphere formation. Am J Cancer Res 2017;7(2) :260-274 [OMICSLINK™ HMGA2 shRNA clone set]
Li, Q., et al. (2017). Overexpression of TACC3 is correlated with tumor aggressiveness and poor prognosis in prostate cancer. Biochemical and Biophysical Research Communications doi: 10.1016/j.bbrc.2017.03.090 [OMICSLINK™ TACC3 shRNA clone set]
Wen, Z., et al. (2017). The clinical significance of isocitrate dehydrogenase 2 in esophageal squamous cell carcinoma. Am J Cancer Res 2017;7(3) :700-714 [OMICSLINK™ IDH2 shRNA clone set]
Wang, M., et al. (2017). HIF-1α promoted vasculogenic mimicry formation in hepatocellular carcinoma through LOXL2 up-regulation in hypoxic tumor microenvironment. Journal of Experimental & Clinical Cancer Research doi: 10.1186/s13046-017-0533-1 [OMICSLINK™ HIF-1α and LOXL2 shRNA clone sets]
Feng, X., et al. (2017). NMI inhibits cancer stem cell traits by downregulating hTERT in breast cancer. Cell Death & Disease doi: 10.1038/cddis.2017.200 [OMICSLINK™ NMI shRNA clone set]
Gu, Y., et al. (2017). Oncogenic function of TUSC3 in non-small cell lung cancer is associated with Hedgehog signalling pathway. Biochimica et Biophysica Acta (BBA) – Molecular Basis of Disease doi: 10.1016/j.bbadis.2017.05.005 [OMICSLINK™ TUSC3 shRNA clone set]
Chen, K., et al. (2017). NleB/SseK effectors from Citrobacter rodentium, Escherichia coli, and Salmonella enterica display distinct differences in host substrate specificity. The Journal of Biological Chemistry doi: 10.1074/jbc.M117.790675 [OMICSLINK™ GAPDH shRNA clone set]
Siqueira, M., et al. (2017). Radial Glia Cells Control Angiogenesis in the Developing Cerebral Cortex Through TGF-β1 Signaling. Molecular Neurobiology doi: 10.1007/s12035-017-0557-8 [OMICSLINK™ TGF-β1 shRNA clone set]
Zhang, Q., et al. (2017). Thymidine phosphorylase promotes metastasis and serves as a marker of poor prognosis in hepatocellular carcinoma. Laboratory Investigation doi: 10.1038/labinvest.2017.51 [OMICSLINK™ TYMP shRNA clone set]
Chen, J., et al. (2017). Fas signaling induces stemness properties in colorectal cancer by regulation of Bmi1. Molecular Carcinogenesis doi: 10.1002/mc.22680 [OMICSLINK™ β-catenin shRNA clone set]
Emery, A.C., et al. (2017). Guanine nucleotide exchange factor Epac2-dependent activation of the GTP-binding protein Rap2A mediates cAMP-dependent growth arrest in neuroendocrine cells. The Journal of Biological Chemistry doi: 10.1074/jbc.M117.79032 [OMICSLINK™ Rit1, RAP2A shRNA clone sets]
Khanh, V.C., et al. (2017). Uremic Toxins Affect the Imbalance of Redox State and Overexpression of Prolyl Hydroxylase 2 in Human Adipose Tissue-Derived Mesenchymal Stem Cells Involved in Wound Healing. Stem Cells and Development doi: 10.1089/scd.2016.0326 [OMICSLINK™ PHD2 shRNA clone set]
Bai, P., et al. (2017). Pleiotrophin, a target of miR-384, promotes proliferation, metastasis and lipogenesis in HBV-related hepatocellular carcinoma. Journal of Cellular and Molecular Medicine doi: 10.1111/jcmm.13213 [OMICSLINK™ PTN shRNA clone set]
Liu, L., et al. (2017). CRY2 is suppressed by FOXM1 mediated promoter hypermethylation in breast cancer. Biochemical and Biophysical Research Communications doi: 10.1016/j.bbrc.2017.06.003 [OMICSLINK™ FOXM1, DNMT3b shRNA clone sets]
Qin, X., et al. (2017). Inhibition of Early Growth Response 1 in the Hippocampus Alleviates Neuropathology and Improves Cognition in an Alzheimer Model with Plaques and Tangles. The American Journal of Pathology doi: 10.1016/j.ajpath.2017.04.018 [OMICSLINK™ EGR1 shRNA clone set]
Li, Q., et al. (2017). PHF21B overexpression promotes cancer stem cell-like traits in prostate cancer cells by activating the Wnt/β-catenin signaling pathway. Journal of Experimental & Clinical Cancer Research doi: 10.1186/s13046-017-0560-y [OMICSLINK™ PHF21B shRNA clone set]
Yuan, B., et al. (2017). Interleukin‑6 RNA knockdown ameliorates acute lung injury induced by intestinal ischemia reperfusion in rats by upregulating interleukin‑10 expression. Molecular Medicine Reports doi: 10.3892/mmr.2017.6932 [OMICSLINK™ IL-6 lentiviral shRNA clone set]
Ayyadurai, S., et al. (2017). Frontline Science: Corticotropin-releasing factor receptor subtype 1 is a critical modulator of mast cell degranulation and stress-induced pathophysiology. Journal of Leukocyte Biology doi: 10.1189/jlb.2HI0317-088RR [OMICSLINK™ CRF1 lentiviral shRNA clone set]
Andriu, A., et al. (2017). Binding of αvβ3 Integrin-Specific Radiotracers Is Modulated by Both Integrin Expression Level and Activation Status. Molecular Imaging and Biology doi:10.1007/s11307-017-1100-z [OMICSLINK™ integrin β shRNA clone set]
Liang, X., et al. (2017). Rictor regulates the vasculogenic mimicry of melanoma via the AKT-MMP-2/9 pathway. Journal of Cellular and Molecular Medicine doi: 10.1111/jcmm.13268 [OMICSLINK™ Rictor shRNA lentiviral clone set]
Cao, H.L. et al (2017). Cordycepin induces apoptosis in human bladder cancer cells via activation of A3 adenosine receptors. Tumor Biology doi: 10.1177/1010428317706915 [OMICSLINK™ A3AR shRNA clone set]
Wang, Z., et al. (2017). Quinolinate Phosphoribosyltransferase is an Antiviral Host Factor Against Hepatitis C Virus Infection. Scientific Reports doi: 10.1038/s41598-017-06254-4 [OMICSLINK™ QPRT shRNA clone set]
Ben-Shmuel, S., et al. (2017). Activating Transcription Factor-5 Knockdown Reduces Aggressiveness of Mammary Tumor Cells and Attenuates Mammary Tumor Growth. Frontiers in Endocrinology doi: 10.3389/fendo.2017.00173 [OMICSLINK™ ATF5 shRNA clone set]
Kelly, N.J. (2017). Hypoxia activates cadherin – 22 synthesis via eIF4E2 to drive the migration, invasion and adhesion of breast cancer and glioma cells. Ph.D. Thesis, University of Guelph [OMICSLINK™ eIF4E2 shRNA clone set]
Song, L.J., et al. (2017). Inhibition of CDK5 Alleviates the Cardiac Phenotypes in Timothy Syndrome. 10.1016/j.stemcr.2017.05.028 [OMICSLINK™ CDK5 shRNA clone set]
Duggan, M.C., et al. (2017). Identification of NRAS isoform 2 overexpression as a mechanism facilitating BRAF inhibitor resistance in malignant melanoma. Proceedings of the National Academy of Sciences of the U.S.A. doi; 10.1073/pnas.1704371114 [OMICSLINK™ NRAS lentiviral shRNA clone set]
Xu, W., et al. (2017). Role of Peroxiredoxin 2 in the Protection Against Ferrous Sulfate-Induced Oxidative and Inflammatory Injury in PC12 Cells. Cellular and Molecular Neurobiology doi: 10.1007/s10571-017-0540-y [OMICSLINK™ rat PRDX2 lentiviral shRNA clone set]
Yong, et al. (2017). Visceral adipose tissue macrophage-targeted TACE silencing to treat obesity-induced type 2 diabetes.Biomaterials 10.1016/j.biomaterials.2017.09.023 [OMICSLINK™ TACE shRNA clone set]
Chen, Y., et al. (2017). The role of LASS2 in regulating bladder cancer cell tumorigenicity in a nude mouse model. Oncology Letters doi: 10.3892/ol.2017.6880 [OMICSLINK™ LASS2 shRNA clone set]
Zhang, J., et al. (2017). Knockdown of FUSE binding protein 1 enhances the sensitivity of epithelial ovarian cancer cells to carboplat…Oncology Letters doi: 10.3892/ol.2017.6978 [OMICSLINK™ FBP1 shRNA clone set]
Gao, L., et al. (2017). Implications of FGF19 on sorafenib-mediated nitric oxide production in hepatocellular carcinoma cells – a short report. Cellular Oncology doi: 10.1007/s13402-017-0354-4 [OMICSLINK™ FGF19 shRNA clone set]
Tey, S.K., et al. (2017). Nuclear Met promotes hepatocellular carcinoma tumorigenesis and metastasis by upregulation of TAK1 and activation of NF-κB pathway. Cancer Letters doi: 10.1016/j.canlet.2017.09.047 [OMICSLINK™ TAK1 shRNA clone set]
Wang, J., et al. (2017). Downregulation of NMI promotes tumor growth and predicts poor prognosis in human lung adenocarcinomas. Molecular Cancer doi: 10.1186/s12943-017-0705-9 [OMICSLINK™ NMI shRNA clone set]
Zhang, S., et al. (2017). miR‑502‑mediated histone methyltransferase SET8 expression is associated with clear cell renal cell carcinoma risk. Oncology Letters doi: 10.3892/ol.2017.7115 [OMICSLINK™ SET8 shRNA clone set]
Lee, J.Y., et al. (2017). Overcoming Monocarboxylate Transporter 8 (MCT8)-Deficiency to Promote Human Oligodendrocyte Differentiation and Myelination. EBiomedicine doi: 10.1016/j.ebiom.2017.10.016 [OMICSLINK™ SLC16A2 shRNA clone set]
Wang, T., et al. (2017). Chemopreventive effects of atractylenolide II on mammary tumorigenesis via activating Nrf2-ARE pathway. Oncotarget doi: 10.18632/oncotarget.20546 [OMICSLINK™ Nrf2 shRNA clone set]
Bi, L., et al. (2017). AJUBA increases the cisplatin resistance through hippo pathway in cervical cancer. Gene doi: 10.1016/j.gene.2017.11.017 [OMICSLINK™ AJUBA shRNA clone set]
Yang, M., et al. (2017). CLDN6 promotes chemoresistance through GSTP1 in human breast cancer. Journal of Experimental & Clinical Cancer Research doi: 10.1186/s13046-017-0627-9 [OMICSLINK™ GSTP1 lentiviral shRNA clone set]
Ikeda, K., et al. (2017). UCP1-independent signaling involving SERCA2b-mediated calcium cycling regulates beige fat thermogenesis and systemic glucose homeostasis. Nature Medicine doi: 10.1038/nm.4429 [OMICSLINK™ Atp2a2 lentiviral shRNA clone set]
Oquendo, A.R., et al. (2017). USE OF RECOMBINANT LYMPHOCYTE ACTIVATION GENE-3 AS A COMPANION THERAPEUTIC FOR PATIENTS AT RISK FOR CARDIOVASCULAR DISEASE AND OTHER CHRONIC INFLAMMATORY DISEASES. United States Patent Application 20170312338 [OMICSLINK™ LAG3 lentiviral shRNA clone set]
Vélez-Aguilera, G., et al. (2017). Control of nuclear β-dystroglycan content is crucial for the maintenance of nuclear envelope integrity and function. Biochimica et Biophysica Acta (BBA) – Molecular Cell Research doi: 10.1016/j.bbamcr.2017.11.013 [OMICSLINK™ CRM1 lentiviral shRNA clone set]
Zahng, Z., et al. (2017). miR-135b-5p Promotes migration, invasion and EMT of pancreatic cancer cells by targeting NR3C2. Biomedicine and Pharmacotherapy doi: 10.1016/j.biopha.2017.11.074 [OMICSLINK™ NR3C2 lentiviral shRNA clone]
Yang, H., et al. (2017). KLF4 protects brain microvascular endothelial cells from ischemic stroke induced apoptosis by transcriptionally activating MALAT1. Biochemical and Biophysical Research Communications doi: 10.1016/j.bbrc.2017.11.205 [OMICSLINK™ KLF4, MALAT1 shRNA clone sets]
Xu, Q., et al. (2017). HSP90 promotes cell glycolysis, proliferation and inhibits apoptosis by regulating PKM2 abundance via Thr-328 phosphorylation in hepatocellular carcinoma. Molecular Cancer doi: 10.1186/s12943-017-0748-y [OMICSLINK™ HSP90 shRNA clone set]
Wen, Y-A., et al. (2017). Phosphoglycerate mutase 1 knockdown inhibits prostate cancer cell growth, migration, and invasion. Asian Journal of Andrology December 22, 2017 [OMICSLINK™ PGM1 shRNA clone set]
Wang, N., et al. (2017). Identification of WT1 as determinant of heptatocellular carcinoma and its inhibition by Chinese herbal medicine Salvia chinensis Benth and its active ingredient protocatechualdehyde. Oncotarget doi: 10.18632/oncotarget.22406 [OMICSLINK™ WT1 shRNA clone set]
Naushad, W., et al. (2017). Structural determinant of BST-2-mediated regulation of breast cancer cell motility: a role for cytoplasmic tail tyrosine residues. Oncotarget doi: 10.18632/oncotarget.22753 [OMICSLINK™ BST-2 shRNA clone set]

2016

Deng, R. et al. (2016) High Expression of the Newly Found Long Noncoding RNA Z38 Promotes Cell Proliferation and Oncogenic Activity in Breast Cancer. Journal of Cancer,2016; 7(5): 576-586. doi: 10.7150/jca.13117 . [siRNAs of Z38, negative control (NC)]
Jr, A.P., et al. (2016). HMGA2 overexpression plays a critical role in the progression of esophageal squamous carcinoma. Oncotoarget March 23, 2016 [OMICSLINK™ HMGA2 shRNA clone set]
Roy, A. et al. (2016) BPOZ-2 Gene Delivery Ameliorates Alpha-Synucleinopathy in A53T Transgenic Mouse Model of Parkinson’s Disease. Scientific Reports,doi:10.1038/srep22067. [Bpoz-2 overexpression construct (cat # EX-Mm12657-Lv104), Bpoz-2-siRNA (cat#MSH042485-LvH1), lentiviral packaging kit, HEK-293Ta cells (Cat # CLv-PK-01), and chemically competent E-Coli cells (Cat # STK200-10)]
Wang , YC. et al. (2016) Knockdown of α-synuclein in cerebral cortex improves neural behavior associated with apoptotic inhibition and neurotrophin expression in spinal cord transected rats. Apoptosis,DOI
10.1007/s10495-016-1218-5. [Recombinant SNCA lentiviral vectors, including coding open reading frame (ORF) and shRNA sequence]
Chen , Z. et al. (2016) miR-33a-5p modulates Japanese Encephalitis Virus Replication by targeting Eukaryotic Translation Elongation Factor 1A1. Journal of Virology, doi:10.1128/JVI.03242-15. [endogenous EEF1A1 protein expression, and the negative control shRNA (sh-NC)]
Sigala , I. et al. (2016) Expression of SRPK1 in gliomas and its role in glioma cell lines viability. Tumor Biology,DOI
10.1007/s13277-015-4738-7. [HSH017724- 1-CU6(OS214865), HSH017724-2-CU6(OS214866), HSH017724-3-CU6(OS214867), and HSH017724-4- CU6(OS214868)]
Gu, Y. et al. (2016) TUSC3 promotes colorectal cancer progression and epithelial‐mesenchymal transition (EMT) through WNT/β‐catenin and MAPK signalling. The Journal of Pathology,DOI: 10.1002/path.4697. [the pEZ-Lv105 and psi-LVRH1GP shRNA lentiviral vector]
Dominick, G. et al. (2016). mTOR regulates the expression of DNA damage response enzymes in long-lived Snell dwarf, GHRKO, and PAPPA-KO mice. Aging Cell doi: 10.1111/acel.12525 [CNOT3 (NM_146176.2) and mouse CNOT6L shRNA clones]
Wang, W., et al. (2016). FABP5 correlates with poor prognosis and promotes tumor cell growth and metastasis in cervical cancer. Tumor Biology doi: 10.1007/s13277-016-5350-1. [FABP5 sgRNA clones]
Shan, B., et al. (2016). TIM-3 promotes the metastasis of esophageal squamous cell carcinoma by targeting epithelial-mesenchymal transition via the Akt/GSK-3β/Snail signaling pathway. Oncology Reports doi: 10.3892/or.2016.4938 [TIM 3 shRNA clone set]
Ciu, J., et al. (2016). MBD3 mediates epigenetic regulation on EPAS1 promoter in cancer. Tumor Biology doi: 10.1007/s13277-016-5237-1 [MBD3 shRNA clone set]
Wang, Y., et al. (2016). Guanylate cyclase-C signaling pathway regulates intestinal inflammatory injury and epithelial barrier function in Caco-2 cells. Int J Clin Exp Pathol 9, 8858 [human GC-C shRNA expression clone set]
Elsafadi, M., et al. (2016). Transgelin is a TGFβ-inducible gene that regulates osteoblastic and adipogenic differentiation of human skeletal stem cells through actin cytoskeleston organization. Cell Death and Disease doi: doi:10.1038/cddis.2016.196 [TAGLN-shRNA clone set]
Sahu, N. et al. (2016). Functional screening implicates miR-371-3p and peroxiredoxin 6 in reversible tolerance to cancer drugs. Nature Communications doi: 10.1038/ncomms12351[PRDX6 shRNA clone set]
Liu, H., et al. (2016). Cip2a promotes cell cycle progression in triple-negative breast cancer cells by regulating the expression and nuclear export of p27Kip1. Oncogene doi: 10.1038/onc.2016.355 [Cip2a shRNA clone set]
Lai, Y., et al. (2016). MiR-384 regulated IRS1 expression and suppressed cell proliferation of human hepatocellular carcinoma. Tumor Biology doi: 10.1007/s13277-016-5233-5 [Lentifect™ lentiviral particles expressing shRNA targeting IRS1]
Song, Y., et al. (2016). RNAi-mediated silencing of TNF-α converting enzyme to down-regulate soluble TNF-α production for treatment of acute and chronic colitis. Jounral of Controlled Release doi: 10.1016/j.jconrel.2016.08.017 [TACE shRNA clone set]
Shi, W., et al. (2016). Olfactomedin 1 negatively regulates NF-κB signalling and suppresses the growth and metastasis of colorectal cancer cells. The Journal of Pathology doi: 10.1002/path.4784 [OLFM1 shRNA clone set]
Chakravarthy, E., et al. (2016). Nerve growth factor (NGF)-mediated regulation of p75NTR expression contributes to chemotherapeutic resistance in triple negative breast cancer cells. Biochemical and Biophysical Research Communications doi: 10.1016/j.bbrc.2016.08.149 [p75 NTR shRNA clone set]
Amin, R., et al. (2016). Dual PPAR-δ PPAR-γ agonists. US Patent US 9422239 B1 [BDNF shRNA clones set]
Zhu, S., et al. (2016). Helicobacter pylori-induced cell death is counteracted by NF-κB-mediated transcription of DARPP-32 . Gut doi: 10.1136/gutjnl-2016-312141 [DARPP-32 shRNA clone set]
Feng, G.Y., et al. (2016). Effects of Alpha-Synuclein on Primary Spinal Cord Neurons Associated with Apoptosis and CNTF Expression, Cellular and Molecular Neurology doi: 10.1007/s10571-016-0420-x. [SNCA shRNA clone set]
Kyritsis, A.P., et al. (2016). Expression of SRPK1 in gliomas and its role in glioma cell lines viability. Tumor Biology doi: 10.1007/s13277-015-4738-7 [CU6 shRNA clone set]
Lee, J., et al. (2016). Orphan GPR110 (ADGRF1) targeted by N-docosahexaenoylethanolamine in development of neurons and cognitive function. Nature Communications doi: 10.1038/ncomms13123 [GPR110 shRNA clone set]
Liu, Y., et al. (2016). LMO2 attenuates tumor growth by targeting the Wnt signaling pathway in breast and colorectal cancer. Scientific Reports doi: 10.1038/srep36050 [LMO2 lentiviral shRNA clone set]
Wang, R., et al. (2016). Histone H4 expression is cooperatively maintained by IKKβ and Akt1 which attenuates cisplatin-induced apoptosis through the DNA-PK/RIP1/IAPs signaling cascade. Scientifc Reports doi: 10.1038/srep41715 [OMICSLINK™ psi-LVRH1GP shRNA clone set]
Ye, W., et al. (2017). Overexpression of SLC34A2 is an independent prognostic indicator in bladder cancer and its depletion suppresses tumor growth via decreasing c-Myc expression and transcriptional activity. Cell Death & Disease doi: 10.1038/cddis.2017.13 [OMICSLINK™ SLC34A2 shRNA clone set]
Hansji, H., et al. (2016). ZFAS1: a long noncoding RNA associated with ribosomes in breast cancer cells. Biology Direct doi: 10.1186/s13062-016-0165-y [OMICSLINK™ ZFAS1 shRNA clone set]
Yang, Y., et al. (2016). Epigenetic CpG Methylation of the Promoter and Reactivation of the Expression of GSTP1 by Astaxanthin in Human Prostate LNCaP Cells. The AAPS Journal doi: 10.1208/s12248-016-0016-x [OMICSLINK™ SETD7 shRNA clone set]
Gokhale, A., et al. (2016). The Proteome of BLOC-1 Genetic Defects Identifies the Arp2/3 Actin Polymerization Complex to Function Downstream of the Schizophrenia Susceptibility Factor Dysbindin at the Synapse. The Journal of Neuroscience doi: 10.1523/JNEUROSCI.1321-16.2016 [OMICSLINK™ Dysbindin shRNA lentiviral clone set]

2015

Lv, Z. et al. (2015) MiR-592 represses FOXO3 expression and promotes the proliferation of prostate cancer cells. Int J Clin Exp Med,Int J Clin Exp Med 2015;8(9):14962-14968. [FOXO3 shRNA(HSH005759; HSH061727)]
Joly, AL. et al. (2015) The HSP90 inhibitor, 17AAG, protects the intestinal stem cell niche and inhibits graft versus host disease development. Oncogene,doi:10.1038/onc.2015.242. [shRNA inserted in the lentiviral vector psiHIV-U6]
Ying, X. et al. (2015) MiR-939 promotes the proliferation of human ovarian cancer cells by repressing APC2 expression. Biomedicine & Pharmacotherapy,Volume 71, April 2015, Pages 64–69. [HSH000364]
Saito, N. et al. (2015) Effect of Notch expression in glioma stem cells on therapeutic response to chemo-radiotherapy in recurrent glioblastoma. Brain Tumor Pathology,July 2015, Volume 32, Issue 3, pp 176-183. [Lentiviral vector encoding shRNA for Notch-1]
MA St John (2015) Inflammatory mediators drive metastasis and drug resistance in head and neck squamous cell carcinoma. The Laryngoscope,DOI: 10.1002/lary.24998. [The shRNA constructs against Human COX-2]
Roy, L. et al. (2015) MiR-24 Is Required for Hematopoietic Differentiation of Mouse Embryonic Stem Cells. PLoS genetics,PLoS Genet 11(1): e1004959. doi:10.1371/journal.pgen.1004959. [a lentivirus expressing an shRNA that binds and inhibits miR-24 (miArrest-24)]
A Rodriguez Oquendo (2015) USE OF LYMPHOCYTE ACTIVATION GENE 3 (LAG-3) EXPRESSION PROFILING AS A BIOMARKER FOR ASSESSING INFLAMMASOMES, CHRONIC INFLAMMATORY DISEASES AND DYSFUNCTIONAL HDL. US Patent ,US Patent 20,150,355,203. [psi-LVRH1MP RNAi silencing vector, scrambled shRNA, lentiviral Mock GFP control vectors]
Wang, X. et al. (2015) Knockdown of RhoA expression alters ovarian cancer biological behavior in vitro and in nude mice. Oncology Reports,Pages: 891-899 DOI: 10.3892/or.2015.4009. [A lentiviral expression vector carrying RhoA shRNA]
Gokhale, A. et al. (2015) The N-Ethylmaleimide-Sensitive Factor and Dysbindin Interact To Modulate Synaptic Plasticity. The Journal of Neuroscience,doi: http://dx.doi.org/10.1523/JNEUROSCI.4724-14.2015. [shRNA-mediated dysbindin knockdowns, shRNA in a psiHIV-U6 vector for lentiviral infection]
Gupta, P. et al. (2015) Inhibition of NADPH oxidase-4 potentiates 2-deoxy-d-glucose induced suppression of glycolysis, migration and invasion in glioblastoma cells: Role of the Akt/HIF1α/HK-2 signaling axis. Antioxidants and Redox Signaling, doi:10.1089/ars.2014.5973. [Nox-4 expression (NM_016931 in pReceiver-M10) vector) and shRNAclones (HSH012143), HK2-shRNA expression clone (HSH008843-CU6), scrambled shRNA (CSHCTR001-CU6)]
Loiselle , JJ. et al. (2015) Post-transcriptional regulation of Rbm5 expression in undifferentiated H9c2 myoblasts. In Vitro Cellular & Developmental Biology – Animal,10.1007/s11626-015-9976-x. [CSHCTR001-nU6 shRNA scrambled control]
Zhou , C. et al. (2015) Adrenomedullin promotes intrahepatic cholangiocellular carcinoma metastasis and invasion by inducing epithelial-mesenchymal transition. Oncology Reports,Pages: 610-616 DOI: 10.3892/or.2015.4034. [Lentivirus containing short hairpin RNAs targeting ADM]
Liu , R. et al. (2015) MiR-498 regulated FOXO3 expression and inhibited the proliferation of human ovarian cancer cells. Biomedicine & Pharmacotherapy,doi:10.1016/j.biopha.2015.04.005. [siRNA-FOXO3, HSH005759]
Yang , Z. et al. (2015) ZEB2 promotes vasculogenic mimicry by TGF-β1 induced epithelial-to-mesenchymal transition in hepatocellular carcinoma. Experimental and Molecular Pathology,doi:10.1016/j.yexmp.2015.03.030. [plasmids carrying ZEB2 and ZEB2 shRNA (or shZEB2)]
Cha , SH. et al. (2015) Loss of parkin promotes lipid rafts-dependent endocytosis through accumulating caveolin-1: implications for Parkinson’s disease. Molecular Meurodegeneration,Published online 2015 Dec 1. doi: 10.1186/s13024-015-0060-5. [shRNA plasmid for rat cav-1]
Sun , Z. et al. (2015) Increased SHP-1 expression results in radioresistance, inhibition of cellular senescence, and cell cycle redistribution in nasopharyngeal carcinoma cells. Radiation Oncology,DOI: 10.1186/s13014-015-0445-1. [lentivirus-mediated SHP-1-shRNA vector (lot: LP-HSH015860-LVRH1MP) and scramble shRNA vector (lot: LP-CSHCTR001-LVRH1MP)]
Yang , L. et al. (2015) LGR5 Promotes Breast Cancer Progression And Maintains Stem‐like Cells Through Activation Of Wnt/β‐Catenin Signaling. STEM CELLS,DOI: 10.1002/stem.2083. [Short hairpin RNA (shRNA) against LGR5]
Liang, W. et al. (2015) miR-892a regulated PPP2R2A expression and promoted cell proliferation of human colorectal cancer cells. Biomedicine & Pharmacotherapy,doi:10.1016/j.biopha.2015.04.015. [PPP2R2A-siRNA#1, HSH014174; PPP2R2A-siRNA#2, HSH055016]

2014

Wang, Y. et al. (2014) Reduction of selenium-binding protein 1 sensitizes cancer cells to selenite via elevating extracellular glutathione: A novel mechanism of cancer-specific cytotoxicity of selenite. Free Radical Biology and Medicine,doi:10.1016/j.freeradbiomed.2014.11.015. [shRNA targeting human SBP1 (shSBP1)]
Campbell, GR. et al. (2014) Autophagy Induction by Histone Deacetylase Inhibitors Inhibits HIV Type 1. Journal of Biological Chemistry,First Published on
December 24, 2014
doi: 10.1074/jbc.M114.605428. [shRNA- insensitive open reading frame (ORF) cDNA lentiviral vectors]
Zhao , X. et al. (2014) Slug promotes hepatocellular cancer cell progression by increasing sox2 and nanog expression. Oncology Reports,Pages: 149-156 DOI: 10.3892/or.2014.3562. [human Slug (5′-CAGACCCATTCTGATGTAAAG-3′) were cloned into the psiHIV-nH1 lentiviral vector system]
Shahzad , U. et al. (2014) Transmyocardial Revascularization Enhances Bone Marrow Stem Cell Engraftment in Infarcted Hearts Through SCF—C-kit and SDF-1—CXCR4 Signaling Axes. Stem Cell Reviews and Reports,DOI
10.1007/s12015-014-9571-7. [shRNA clone against rat CXCR4 receptor]
Maxson, JE. et al. (2014) Ligand Independence of the T618I Mutation in the Colony-stimulating Factor 3 Receptor (CSF3R) Protein Results from Loss of O-Linked Glycosylation and Increased …. Journal of Biological, doi: 10.1074/jbc.M113.508440.. [CSF3R transcript variant 1 (NM_000760.2) pDONR]
Vásquez-Limeta, A. et al. (2014) Nuclear Import of β-Dystroglycan Is Facilitated by Ezrin-Mediated Cytoskeleton Reorganization. PLOS ONE, 2014 Mar 5;9(3):e90629. doi: 10.1371/journal.pone.0090629. [RNAi (CSHCTR001-mH1)]
Gao, J. et al. (2014) Emodin Suppresses Hyperglycemia-Induced Proliferation and Fibronectin Expression in Mesangial Cells via Inhibiting cFLIP . PLOS ONE, DOI: 10.1371/journal.pone.0093588. [rat cFLIPL shRNA(RSH047914-HIVU6)]
Tien, DN. et al. (2014) AMAP1 as a negative-feedback regulator of nuclear factor-κB under inflammatory conditions. Scientific Reports, Sci Rep. 2014 May 28;4:5094. doi: 10.1038/srep05094.. [shAMAP1，shControl]
Liu, R. et al. (2014) Endoplasmic Reticulum Protein 29 Protects Cortical Neurons From Apoptosis and Promoting Corticospinal Tract Regeneration to Improve Neural Behavior via …. Molecular Neurobiology, DOI:10.1007/s12035-014-8681-1. [shRNA]
Han, P. et al. (2014) Pituitary Adenylate Cyclase Activating Polypeptide protects against β-amyloid toxicity. Neurobiology of Aging, 2014 Sep;35(9):2064-71. doi: 10.1016/j.neurobiolaging.2014.03.022. [shRNA(Cat# MSH032833)]
Zhang, C. et al. (2014) CtBP2 could promote prostate cancer cell proliferation through c-Myc signaling. Gene, 2014 Aug 1;546(1):73-9. doi: 10.1016/j.gene.2014.05.032.. [CtBP2 shRNAs and non-target shRNAs]
Gao, J. et al. (2014) Emodin Suppresses Hyperglycemia-Induced Proliferation and Fibronectin Expression in Mesangial Cells via Inhibiting cFLIP. PLOS ONE, 2014 Apr 1;9(4):e93588. doi: 10.1371/journal.pone.0093588. [rat cFLIPL shRNA]
Liu, Q. et al. (2014) Melanoma NOS1 expression promotes dysfunctional IFN signaling. Journal of Clinical Investigation, 2014 May 1;124(5):2147-59.. [HSH011865-HIVmH1]

2013

Morquecho-León, MA. et al (2013) Isoforms of protein kinase C involved in phorbol ester-induced sphingosine 1-phosphate receptor 1 phosphorylation and desensitization. Biochimica et Biophysica Acta (BBA) – Molecular Cell Research, Volume 1843, Issue 2, February 2014, Pages 327–334. [shRNA plasmid].
Zhou, Y. et al (2013) miR-203 induces oxaliplatin resistance in colorectal cancer cells by negatively regulating ATM kinase. Molecular Oncology, Available online 8 October 2013. [shRNA plasmid, Lentiviral miR-203 and miR-203 expression inhibitor constructs].
Wang, WS. et al (2013) DMOG Ameliorates IFN-γ-Induced Intestinal Barrier Dysfunction by Suppressing PHD2-Dependent HIF-1α Degradation. Journal of Interferon & Cytokine Research, Volume: 34 Issue 1: January 9, 2014. [shRNA].
Dai, Y. et al (2013) Characterization of the oncogenic function of centromere protein F in hepatocellular carcinoma. Biochemical and Biophysical Research Communications, Volume 436, Issue 4, 12 July 2013, Pages 711–718. [shRNA plasmid].
Cahill, ME. et al (2013) Neuregulin1 signaling promotes dendritic spine growth through kalirin. Journal of Neurochemistry, Volume 126, Issue 5, pages 625–635, September 2013. [ErbB4 shRNA and a scrambled control].
Yu, F. et al (2013) Deficiency of Kruppel‐like factor KLF4 in mammary tumor cells inhibits tumor growth and pulmonary metastasis and is accompanied by compromised recruitment of …. International Journal of Cancer, Volume 133, Issue 12, pages 2872–2883, 15 December 2013. [shRNA].
Popovics, P. et al (2013) Phospholipase C‐η2 is required for retinoic acid‐stimulated neurite growth. Journal of Neurochemistry, Volume 124, Issue 5, pages 632–644, March 2013. [PLCη2-targeted].
Roff, A.N. et al (2013) Post-transcriptional Regulation of Meprin α by the RNA-binding Proteins Hu Antigen R (HuR) and Tristetraprolin (TTP). Journal of Biological Chemistry, 288, 4733-4743. [TTP, HuR, or negative control shRNA constructs].
Ku, M.C. et al (2013) GDNF mediates glioblastoma-induced microglia attraction but not astrogliosis. Acta neuropathologica, (2013): 1-12. [GDNF OmicsLink™ short hairpin RNA (shRNA)].
Xie, L. et al (2013) RalA GTPase Tethers Insulin Granules to L‐and R‐Type Calcium Channels Through Binding α2δ‐1 Subunit. Traffic, Volume 14, Issue 4, pages 428–439, April 2013. [Ca v α 2 δ-1].
Aikawa, M. et al (2013) NOTCH INHIBITION IN THE TREATMENT AND PREVENTION OF A METABOLIC DISEASE OR DISORDER AND CARDIOVASCULAR COMPLICATIONS THEREOF. U.S. Patent No. 20,130,064,832. 14 Mar. 2013. [mouse Dll4].
Kim, S.J. et al (2013) Regulation of dendritic cell activation by microRNA let-7c and BLIMP1. Journal of Clinical Investigation, 2013 February 1; 123(2): 823–833. [mouse Blimp1, lentivirus vector].
Zhu, S. et al (2013) Regulation of CXCR4-mediated invasion by DARPP-32 in gastric cancer cells. Molecular Cancer Research 11.1 (2013): 86-94. [Lentivirus expressing DARPP-32, short hairpin RNA (shRNA)-DARPP-32, or control shRNA].

2012

Siouda, M. et al. (2012) Transcriptional Regulation of the Human Tumor Suppressor DOK1 by E2F1. Molecular and Cellular Biology, December 2012 vol. 32 no. 23 4877-4890. [DOK1-shRNA in psiHIV-H1 vector].
Grespi, F. et al. (2012) P73 and age-related diseases: is there any link with Parkinson. Aging, Volume 4, N 12. [exon 13 shRNA].
Chen, X. et al. (2012) Analysis of Substrates of Protein Kinase C Isoforms in Human Breast Cells By The Traceable Kinase Method. Biochemistry, 2012, 51 (36), pp 7087–7097.
Song, J. et al. (2012). Tumour-derived IL-10 within tumour microenvironment represses the antitumour immunity of Socs1-silenced and sustained antigen expressing DCs. European Journal of Cancer, Volume 48, Issue 14, September 2012, Pages 2252–2259. [pEZX-IL-10-shRNA].
Lundh, M. et al. (2012) Histone deacetylases 1 and 3 but not 2 mediate cytokine-induced beta cell apoptosis in INS-1 cells and dispersed primary islets from rats and are differentially regulated in the islets of type 1 diabetic children. Diabetologia, Volume 55, Number 9 (2012), 2421-2431, DOI: 10.1007/s00125-012-2615-0. [HDAC2, HDAC3].
Kim, J. et al. (2012) GLTSCR2 contributes to the death resistance and invasiveness of hypoxia-selected cancer cells. FEBS Letters, Volume 586, Issue 19, 21 September 2012, Pages 3435–3440. [GLTSCR2].
Leone, V. et al. (2012) Thyrotropin Regulates Thyroid Cell Proliferation by Up-Regulating miR-23b and miR-29b that Target SMAD3. The Journal of Clinical Endocrinology & Metabolism September 1, 2012 vol. 97 no. 9 3292-3301. [rat CREB1].
Belkhiri, A. et al. (2012) Resistance to TRAIL is mediated by DARPP-32 in gastric cancer. Clin Cancer Res July 15, 2012 18; 3889. [DARPP-32].
Ridgway, L. et al. (2012) Heparanase-induced GEF-H1 signaling regulates the cytoskeletal dynamics of brain metastatic breast cancer cells. Mol Cancer Res June 2012 10; 689. [GEF-H1].
Peng, D. et al. (2012) Glutathione peroxidase 7 protects against oxidative DNA damage in oesophagealcells. Gut 2012;61:1250-1260 doi:10.1136/gutjnl-2011-301078. [GPX7 shRNA lentiviral particles].
Wade, A. et al. (2012) Activated Leukocyte Cell Adhesion Molecule (Alcam) Modulates NeurotrophinSignaling. Journal of Neurochemistry Volume 121, Issue 4, pages 575–586, May 2012. [shRNA ALCAM].
Zhang, M. et al. (2012) Autophagy and Apoptosis Act as Partners to Induce Germ Cell Death after Heat Stress in Mice. PLoS ONE 7(7): e41412. doi:10.1371/journal.pone.0041412. [Mouse Atg7].
Pérez-Gómez, E. et al. (2012) The orphan receptor GPR55 drives skin carcinogenesis and is upregulated in human squamous cell carcinomas. Oncogene , (2 July 2012) | doi:10.1038/onc.2012.278. [GPR55 (psi-U6-EGFP)].
Jerebtsova, M. et al. (2012) HIV-1 Resistant CDK2-Knockdown Macrophage-Like Cells Generated from 293T Cell-Derived Human Induced Pluripotent Stem Cells. Biology 2012, 1(2), 175-195; doi:10.3390/biology1020175. [CDK2].
Lee, S. et al. (2012) Nucleolar protein GLTSCR2 stabilizes p53 in response to ribosomal stresses. Cell Death and Differentiation (2012) 19, 1613–1622; doi:10.1038/cdd.2012.40; published online 20 April 2012. [Lentivector-based shRNA system].
Dong, J. et al. (2011) c-Myc Regulates Self-Renewal in Bronchoalveolar Stem Cells. PLoS ONE 8 (6) [Mouse c-Myc shRNA]
Feng, G.S. et al. (2011) G-CSF receptor activation of the Src kinase Lyn is mediated by Gab2. Blood doi: 10.1182/blood-2009-12-261636.
Leone, V. et al. (2011) A TSH-CREB1-microRNA Loop Is Required for Thyroid Cell Growth. Molecular Endocrinology doi:10.1210/me.2011-0014 [CREB1 shRNA]
Kraskiewicz, H. et al. (2011) Partial XBP1 knockdown does not affect viability of oligodendrocyte precursor cells exposed to new models of hypoxia and ischemia in vitro. Journal of Neuroscience Research 5 (89): 661-673 [rat XBP1]
Zheng, L. et al. (2011) Tyrosine 23 Phosphorylation-Dependent Cell-Surface Localization of Annexin A2 Is Required for Invasion and Metastases of Pancreatic Cancer. PLoS ONE 4 (6) [mouse ANXA2 shRNA Lenti particles]
Zhu, S. et al. (2011) DARPP-32 Increases Interactions Between Epidermal Growth Factor Receptor and ERBB3 to Promote Tumor Resistance to Gefitinib. Gastroenterology. doi:10.1053/j.gastro.2011.06.070 [DARPP 32 shRNA]
Hao, S. et al. (2011) Differential regulation of NFAT5 by NKCC2 isoforms in medullary thick ascending limb (mTAL) cells. AJP-Renal Physiology doi: 10.?1152/?ajprenal.00408.2010. [shRNA clone]
Kim, YD et al. (2011) NSrp70 is a novel nuclear speckle-related protein that modulates alternative pre-mRNA splicing in vivo. Nucleic Acids Research doi: 10.1093/nar/gkq1267. [NSrp70]
Zhang, L. et al. (2011) MicroRNA-1258 Suppresses Breast Cancer Brain Metastasis by Targeting Heparanase. Cancer Research 71;645. [shRNA clone]
St John, MA et al. (2009) Proinflammatory mediators upregulate snail in head and neck squamous cell carcinoma. Clinical Cancer Research 15; 6018. [Human Cox-2]

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