All human and mice ORF clones and related Lentivirus, AAV particles and recombinant proteins provided by GeneCopoeia are fully sequenced using Sanger sequencing by capillary electrophoresis and Amino Acid Sequences are guaranteed to be matched with NCBI database.

Secrete-Pair Luciferase Kit Publications

View selected publications citing GeneCopoeia’s Secrete-Pair™ Dual Luminescence Assay System from the recent literature

2023

Veys, C., et al. (2023). MiR-4270 acts as a tumor suppressor by directly targeting Bcl-xL in human osteosarcoma cells. Front Oncol. doi: 10.3389/fonc.2023.1220459 [miTarget™ BCL2, BCL2L1, MCL1 3′ UTR miRNA Target Clone; Secrete-Pair™ Dual Luminescence Assay Kit]
Kim, H.W., et al. (2023). ELOVL2-AS1 suppresses tamoxifen resistance by sponging miR-1233-3p in breast cancer. Epigenetics. doi: 10.1080/15592294.2023.2276384 [Secrete-Pair™ Dual Luminescence Assay Kit; dual-luciferase reporter vector]
Yu, C., et al. (2023). Flot2 acts as a novel mediator of podocyte injury in proteinuric kidney disease. Int J Biol Sci doi: 10.7150/ijbs.78945 [OMICSLINK™ empty vector; GLuc-ON™ promoter reporter clone; Lenti-Pac™ HIV Expression Packing Kit; Secrete-Pair™ Dual Luminescence Assay Kit]
Ke, H., et al. (2023). Landscape of pathogenic mutations in premature ovarian insufficiency. Nature Medicine doi: 10.1038/s41591-022-02194-3 [OMICSLINK™ empty vector; Secrete-Pair™ dual luminescence kit]
Lv, Y., et al. (2023). RBM46 is essential for gametogenesis and functions in post-transcriptional roles affecting meiotic cohesin subunits. doi: 10.1093/procel/pwac040 [Secrete-Pair™ Dual Luminescence Assay Kit]
Zhu, L., et al. (2023). A Zeb1/MtCK1 metabolic axis controls osteoclast activation and skeletal remodeling. The EMBO Journal doi: 10.15252/embj.2022111148 [Secrete Pair™ Gaussia Luciferase Assay Kit; Secrete-Pair™ Dual Luminescence Assay Kit]
Tsukui, D., et al. (2023). GM-CSF receptor/SYK/JNK/FOXO1/CD11c signaling promotes atherosclerosis. iScience doi: 10.1016/j.isci.2023.107293[OMICSLINK™ Lentiviral expression clone; Secrete-Pair™ Dual Luminescence Assay Kit]
Wischmann, F-J., et al. (2023). Tumor suppressor miR-218 directly targets epidermal growth factor receptor (EGFR) expression in triple-negative breast cancer; sensitizing cells to irradiation. J Cancer Res Clin Oncol doi: 10.1007/s00432-023-04750-x [Secrete-Pair™ Dual Luminescence Assay Kit; miTarget™ 3′ UTR Clone]
Vyas, H., et al. (2023). miR34a-5p impedes CLOCK expression in chronodisruptive C57BL/6J mice and potentiates pro-atherogenic manifestations. PLoS One doi: 10.1371/journal.pone.0283591 [Secrete-Pair™ Dual Luminescence Assay Kit; miTarget™ 3′ UTR Clone]
Wang, Q., et al. (2023). A Novel Circ_Arf3/miR-452-5p/Mbnl1 Axis Regulates Proliferation and Expression of Fibrosis-Related Proteins of Mouse Mesangial Cells Under High Glucose. Diabetes Metab Syndr Obes doi: 10.2147/DMSO.S400530 [Secrete-Pair™ Dual Luminescence Assay Kit]
Steadman, K., et al. (2023). Autonomous action and cooperativity between the ONECUT2 transcription factor and its 3′ untranslated region. Front Cell Dev Biol doi: 10.3389/fcell.2023.1206259 [Secrete-Pair™ Dual Luminescence Assay Kit]
Liu, H., et al. (2023). Isorhamnetin and anti-PD-L1 antibody dual-functional mesoporous silica nanoparticles improve tumor immune microenvironment and inhibit YY1-mediated tumor progression. J Nanobiotechnology doi: 10.1186/s12951-023-01967-3 [Secrete-Pair™ Dual Luminescence Assay Kit]
Li, H., et al. (2023). FOXO3 regulates Smad3 and Smad7 through SPON1 circular RNA to inhibit idiopathic pulmonary fibrosis. Int J Biol Sci doi: 10.7150/ijbs.80140 [Secrete-Pair™ Dual Luminescence Assay Kit]
Sun, B., et al. (2023). Engineered induced-pluripotent stem cell derived monocyte extracellular vesicles alter inflammation in HIV humanized mice. Extracell Vesicles Circ Nucl Acids doi: 10.20517/evcna.2022.11 [miTarget™ 3′ UTR Clone; Secrete-Pair™ Dual Luminescence Assay Kit ]
Zhang, J., et al. (2023). Naringenin in Si-Ni-San formula inhibits chronic psychological stress-induced breast cancer growth and metastasis by modulating estrogen metabolism through FXR/EST pathway. J Adv Res doi: 10.1016/j.jare.2022.06.006 [GLuc-ON™ promoter-reporter clone; Secrete-Pair™ Dual Luminescence Assay Kit]
Dykxhoorn, D.M., et al. (2023). MicroRNA-423-5p Mediates Cocaine-Induced Smooth Muscle Cell Contraction by Targeting Cacna2d2. Int J Mol Sci doi: 10.3390/ijms24076584 [pEZX-MT05 vector; miTarget™ Cacna2d2 3′ UTR Clone; Secrete-Pair™ Dual Luminescence Assay Kit]
Ke, H., et al. (2023). Landscape of pathogenic mutations in premature ovarian insufficiency. Nat Med doi: 10.1038/s41591-022-02194-3 [Secrete-Pair™ Dual Luminescence Assay Kit]
Kuang, Y., et al. (2023). The developmental regulator HAND1 inhibits gastric carcinogenesis through enhancing ER stress apoptosis via targeting CHOP and BAK which is augmented by cisplatin. Int J Biol Sci doi: 10.7150/ijbs.76345 [Secrete-Pair™ Dual Luminescence Assay Kit]
Palakurti, R., et al. (2023). Inducible miR-1224 silences cerebrovascular Serpine1 and restores blood flow to the stroke-affected site of the brain. Mol Ther Nucleic Acids doi: 10.1016/j.omtn.2022.12.019 [Secrete-Pair™ Dual Luminescence Assay Kit]

2022

Weissman, R., et al. (2022). MicroRNA-15a-5p acts as a tumor suppressor in histiocytosis by mediating CXCL10-ERK-LIN28a-let-7 axis. Leukemia doi: 10.1038/s41375-021-01472-2 [Secrete-Pair™ Dual Luminescence Assay Kit]
Penke, L.R., et al. (2022). KLF4 is a therapeutically tractable brake on fibroblast activation that promotes resolution of pulmonary fibrosis. JCI Insight doi: 10.1172/jci.insight.160688 [Secrete-Pair™ Dual Luminescence Assay Kit; OMICSLINK™ KLF4 Lentiviral ORF expression clone]
Al-Zikri, P.N.H., et al. (2022). Transplantation of IGF-1-induced BMSC-derived NPCs promotes tissue repair and motor recovery in a rat spinal cord injury model. Heliyon doi: 10.1016/j.heliyon.2022.e10384 [Secrete-Pair™ Dual Luminescence Assay Kit; OMICSLINK™ ORF expression clone]
Dong, M., et al. (2022). Milk-derived small extracellular vesicles: nanomaterials to promote bone formation. J Nanobiotechnology doi: 10.1186/s12951-022-01580-w [Secrete-Pair™ Dual Luminescence Assay Kit; GLuc-ON™ GJA1 promoter-reporter clone]
Hong, D.E., et al. (2022). A Natural CHI3L1—Targeting Compound; Ebractenoid F; Inhibits Lung Cancer Cell Growth and Migration and Induces Apoptosis by Blocking CHI3L1/AKT Signals. Molecules doi: 10.3390/molecules28010329 [Secrete-Pair™ Dual Luminescence Assay Kit]
Zhao, D.Y., et al. (2022). CHD6 promotes broad nucleosome eviction for transcriptional activation in prostate cancer cells. Nucleic Acids Res doi: 10.1093/nar/gkac1090 [Secrete-Pair™ Dual Luminescence Assay Kit]
Matute, J.D., et al. (2022). Intelectin-1 binds and alters the localization of the mucus barrier–modifying bacterium Akkermansia muciniphila. J Exp Med doi: 10.1084/jem.20211938 [Secrete-Pair™ Dual Luminescence Assay Kit]
Dong, Y.J., et al. (2022). Inhibition of the MAPK/c-Jun-EGR1 Pathway Decreases Photoreceptor Cell Death in the rd1 Mouse Model for Inherited Retinal Degeneration. Int J Mol Sci doi: 10.3390/ijms232314600 [Secrete-Pair™ Dual Luminescence Assay Kit]
Lv, Y., et al. (2022). RBM46 is essential for gametogenesis and functions in post-transcriptional roles affecting meiotic cohesin subunits. Protein Cell doi: 10.1093/procel/pwac040 [Secrete-Pair™ Dual Luminescence Assay Kit]
Yuan, B., et al. (2022). Structure of the Ebola virus polymerase complex. Nature doi: 10.1038/s41586-022-05271-2 [Secrete-Pair™ Dual Luminescence Assay Kit]
Zhao, X., et al. (2022). Acute sleep deprivation upregulates serotonin 2A receptors in the frontal cortex of mice via the immediate early gene Egr3. Molecular Psychiatry doi: 10.1038/s41380-021-01390-w [Secrete-Pair™ Dual Luminescence Assay Kit]
Smith, A.J., et al. (2022). miR-520a-5p regulates Frizzled 9 expression and mediates effects of cigarette smoke and iloprost chemoprevention. Scientific Reports doi: 10.1038/s41598-022-06292-7 [Secrete-Pair™ Dual Luminescence Assay Kit]
Wang, R. and Lahiri, D.K. (2022). Effects of microRNA-298 on APP and BACE1 translation differ according to cell type and 3′-UTR variation. Scientific Reports doi: 10.1038/s41598-022-05164-4 [Secrete-Pair™ Dual Luminescence Assay Kit]
Li, J., et al. (2022). Auts2 deletion involves in DG hypoplasia and social recognition deficit: The developmental and neural circuit mechanisms. Science Advances doi: 10.1126/sciadv.abk1238 [Secrete-Pair™ Dual Luminescence Assay Kit]
Shemirani, R., et al. (2022). A miRNA derived from amelogenin exon4 regulates expression of transcription factor Runx2 by directly targeting upstream activators Nfia and Prkch. The Journal of Biological Chemistry doi: 10.1016/j.jbc.2022.101807 [Secrete-Pair™ Dual Luminescence Assay Kit]
Veys, C., et al. (2022). Tumor Suppressive Role of miR-342-5p and miR-491-5p in Human Osteosarcoma Cells. Pharmaceuticals doi: 10.3390/ph15030362 [Secrete-Pair™ Dual Luminescence Assay Kit]
Yang, B., et al. (2022). Evaluation of Early Biomarkers of Atherosclerosis Associated with Polychlorinated Biphenyl Exposure: An in Vitro and in Vivo Study. Environmental Health Perspectives doi: 10.1289/EHP9833 [Secrete-Pair™ Dual Luminescence Assay Kit]
Gomes, A. P., et al. (2022). Altered propionate metabolism contributes to tumour progression and aggressiveness. Nature Metabolism doi: 10.1038/s42255-022-00553-5 [Secrete-Pair™ Dual Luminescence Assay Kit]
Xia, Y., et al. (20220. Neuronal C/EBP/AEP pathway shortens life span via selective GABAnergic neuronal degeneration by FOXO repression. Science Advances doi: 10.1126/sciadv.abj8658 [Secrete-Pair™ Dual Luminescence Assay Kit]
Jones, T.M., et al. (2022). Targeted CUL4A inhibition synergizes with cisplatin to yield long-term survival in models of head and neck squamous cell carcinoma through a DDB2-mediated mechanism. Cell Death & Disease doi: 10.1038/s41419-022-04798-6 [Secrete-Pair™ Dual Luminescence Assay Kit]
Hecker, M., et al. (2022). Implication of genetic variants in primary microRNA processing sites in the risk of multiple sclerosis. eBiomedicine doi: 10.1016/j.ebiom.2022.104052 [Secrete-Pair™ Dual Luminescence Assay Kit]
Ortiz-Cuaran, S., et al. (2022). Epithelial-to-mesenchymal transition promotes immune escape by inducing CD70 in non-small cell lung cancer. European Journal of Cancer doi: 10.1016/j.ejca.2022.03.038 [Secrete-Pair™ Dual Luminescence Assay Kit]
Son, E.S., e al. (2022). miRNA-6515-5p regulates particulate matter-induced inflammatory responses by targeting CSF3 in human bronchial epithelial cells. Toxicology in vitro doi: 10.1016/j.tiv.2022.105428 [Secrete-Pair™ Dual Luminescence Assay Kit]
Nguyen, M.T., et al. (2022). The matricellular protein CCN5 induces apoptosis in myofibroblasts through SMAD7-mediated inhibition of NFκB. PLOS ONE doi: 10.1371/journal.pone.0269735 [Secrete-Pair™ Dual Luminescence Assay Kit]
Chen, C., et al. (2022). Gemcitabine resistance of pancreatic cancer cells is mediated by IGF1R dependent upregulation of CD44 expression and isoform switching. Cell Death & Disease doi: 10.1038/s41419-022-05103-1 [Secrete-Pair™ Dual Luminescence Assay Kit]]
McCoy, M.G., et al. (2022) MicroRNA-375 repression of Kruppel-like factor 5 improves angiogenesis in diabetic critical limb ischemia. Angiogenesis doi: 10.1007/s10456-022-09856-3 [Secrete-Pair™ Dual Luminescence Assay Kit]]

2021

Pellegrino, R., et al. (2021). Serum Response Factor (SRF) Drives the TranscriptionalUpregulation of the MDM4 Oncogene in HCC. Cancers doi: 10.3390/cancers13020199 [Secrete-Pair™ Dual Luminescence Assay Kit]
Sivaprakasam, S., et al. (2021). SLC6A14 deficiency is linked to obesity, fatty liver, and metabolic syndrome but only under conditions of a high-fat diet. Biochimica et Biophysica Acta (BBA) – Molecular Basis of Disease doi: 10.1016/j.bbadis.2021.166087 [Secrete-Pair™ Dual Luminescence Assay Kit]
JIang, Q., et al. (2021). Inflammation-driven deaminase deregulation fuels human pre-leukemia stem cell evolution. Cell Reports doi: 10.1016/j.celrep.2020.108670 [Secrete-Pair™ Dual Luminescence Assay Kit]
Liu, J., et al. (2021). NUPR1 is a critical repressor of ferroptosis. Nature Communications doi: 10.1038/s41467-021-20904-2 [Secrete-Pair™ Dual Luminescence Assay Kit]
Kuang, F., et al. (2021). MGST1 is a redox-sensitive repressor of ferroptosis in pancreatic cancer cells. Cell Chemical Biology doi: 10.1016/j.chembiol.2021.01.006 [Secrete-Pair™ Dual Luminescence Assay Kit]
Rippe, C., et al. (2021). NG2/CSPG4, CD146/MCAM and VAP1/AOC3 are regulated by myocardin-related transcription factors in smooth muscle cells. Scientific Reports doi: 10.1038/s41598-021-85335-x [Secrete-Pair™ Dual Luminescence Assay Kit]
Wang, C., et al. (2021). Elafin promotes tumour metastasis and attenuates the anti-metastatic effects of erlotinib via binding to EGFR in hepatocellular carcinoma. Journal of Experimental & Clinical Cancer Research doi: 10.1186/s13046-021-01904-y [Secrete-Pair™ Dual Luminescence Assay Kit]
Xu, J., et al.. (2021). E47 upregulates ΔNp63α to promote growth of squamous cell carcinoma. Cell Death & Disease doi: 10.1038/s41419-021-03662-3 [Secrete-Pair™ Dual Luminescence Assay Kit]
Huang, J., et al. (2021). RUNX1 regulates SMAD1 by transcriptionally activating the expression of USP9X, regulating the activation of hepatic stellate cells and liver fibrosis. European Journal of Pharmacology doi: 10.1016/j.ejphar.2021.174137 [Secrete-Pair™ Dual Luminescence Assay Kit]
Aldakheel, F.M., et al. (2021). MicroRNA-21 inhibits ovarian granulosa cell proliferation by targeting SNHG7 in premature ovarian failure with polycystic ovary syndrome, Journal of Reproductive Immunology doi: 10.1016/j.jri.2021.103328 [Secrete-Pair™ Dual Luminescence Assay Kit]
Sun, H., et al. (2021). Pathogenicity of novel reassortant Eurasian avian-like H1N1 influenza virus in pigs. Virology doi: 10.1016/j.virol.2021.06.001 [Secrete-Pair™ Dual Luminescence Assay Kit]
Liu, F., et al. (2021). miR-24 controls the regenerative competence of hair follicle progenitors by targeting Plk3. Cell Reports doi: 10.1016/j.celrep.2021.109225 [Secrete-Pair™ Dual Luminescence Assay Kit]
Peng, T., et al. (2021). HIF-1αis a negative regulator of interferon regulatoryfactors: Implications for interferon production byhypoxic monocytes. Proceedings of the National Academy of Sciences of the United Sates of America doi: 10.1073/pnas.2106017118[Secrete-Pair™ Dual Luminescence Assay Kit]
Liu, S., et al. (2021). TRIB3‒GSK-3β interaction promotes lung fibrosis and serves as a potential therapeutic target. Acta Pharmaceutica Sinica B doi: 10.1016/j.apsb.2021.06.017 [Secrete-Pair™ Dual Luminescence Assay Kit]
Allouche, J., et al. (2021). NNT mediates redox-dependent pigmentation via a UVB- and MITF-independent mechanism. Cell doi: 10.1016/j.cell.2021.06.022 [Secrete-Pair™ Dual Luminescence Assay Kit]
Rochford, I., et al. (2021). Evidence for reprogramming of monocytes into reparative alveolar macrophages in vivo by targeting PDE4b, Lung Cellular and Molecular Physiology doi: 10.1152/ajplung.00145.2021 [Secrete-Pair™ Dual Luminescence Assay Kit]
Ofir-Birin, Y., et al. (2021). Malaria parasites both repress host CXCL10 and use it as a cue for growth acceleration. Nature Communications doi: 10.1038/s41467-021-24997-7 [Secrete-Pair™ Dual Luminescence Assay Kit]
Zhao, M., et al. (2021). Myeloid neddylation targets IRF7 and promotes host innate immunity against RNA viruses. PLOS Pathogens doi: 10.1371/journal.ppat.1009901 [Secrete-Pair™ Dual Luminescence Assay Kit]
Katayoshi, T., et al. (2021). Low-molecular-weight whey proteins promote collagen production in dermal fibroblasts via the TGF-β receptor/Smad pathway. Bioscience, Biotechnology, and Biochemistry doi: 10.1093/bbb/zbab155 [Secrete-Pair™ Dual Luminescence Assay Kit]
Wu, Z.,, et al. (2021). CDK13-Mediated Cell Cycle Disorder Promotes Tumorigenesis of High HMGA2 Expression Gastric Cancer. Frontiers in Molecular Biosciences doi: 10.3389/fmolb.2021.707295 [Secrete-Pair™ Dual Luminescence Assay Kit]
Tao, Y., et al.. (2021). MUC1 Promotes Mesangial Cell Proliferation and Kidney Fibrosis in Diabetic Nephropathy Through Activating STAT and β-Catenin Signal Pathway. DNA and Cell Biology doi: 10.1089/dna.2021.0098 [Secrete-Pair™ Dual Luminescence Assay Kit]
Tw, W., et al. (2021). TCF4 enhances hepatic metastasis of colorectal cancer by regulating tumor-associated macrophage via CCL2/CCR2 signaling. Cell Death & Disease doi: 10.1038/s41419-021-04166-w [Secrete-Pair™ Dual Luminescence Assay Kit]
Sharma, N., et al. (2021). Herpes simplex virus 1 evades cellular antiviral response by inducing microRNA-24, which attenuates STING synthesis. PLOS Pathogens doi: 10.1371/journal.ppat.1009950 [Secrete-Pair™ Dual Luminescence Assay Kit]
Chunchacha, P., et al. (2021). Fortilin inhibits p53, halts cardiomyocyte apoptosis, and protects the heart against heart failure. Cell Death Discovery doi: 10.1038/s41420-021-00692-w [Secrete-Pair™ Dual Luminescence Assay Kit]
Weissman, R., et al. (2021). MicroRNA-15a-5p acts as a tumor suppressor in histiocytosis by mediating CXCL10-ERK-LIN28a-let-7 axis. Leukemia doi: 10.1038/s41375-021-01472-2 [Secrete-Pair™ Dual Luminescence Assay Kit]
Mukhopadhyay, C., et al. (2021). G3BP1 inhibits Cul3SPOP to amplify AR signaling and promote prostate cancer. Nature Communications doi: 10.1038/s41467-021-27024-x [Secrete-Pair™ Dual Luminescence Assay Kit]
Fernando, R., et al. (2021). Therapeutic IGF-I receptor inhibition alters fibrocyte immune phenotype in thyroid-associated ophthalmopathy. Proceedings of the National Academy of Sciences of the United States of America doi: 10.1073/pnas.2114244118 [Secrete-Pair™ Dual Luminescence Assay Kit]

2020

Lu, Y-h., et al. (2020). Empagliflozin Attenuates Hyperuricemia by Upregulation of ABCG2 via AMPK/AKT/CREB Signaling Pathway in Type 2 Diabetic Mice. International Journal of Biological Sciences doi: 10.7150/ijbs.33007 [Secrete-Pair™ Dual Luminescence Assay Kit]
Han, Y., et al. (2020). Remodeling of Zn2+ Homeostasis Upon Differentiation of Mammary Epithelial Cells. Metallomics doi: 10.1039/C9MT00301K [Secrete-Pair™ Dual Luminescence Assay Kit]
Nakamura, M., et al. (2020). MicroRNA‑22 enhances radiosensitivity in cervical cancer cell lines via direct inhibition of c‑Myc binding protein, and the subsequent reduction in hTERT expression. Oncology Letters doi: 10.3892/ol.2020.11344 [Secrete-Pair™ Dual Luminescence Assay Kit]
Zhang, C., et al. (2020). Activation of GPR43 suppresses TNF-α-induced inflammatory response in human fibroblast-like synoviocytes. Archives of Biochemistry and Biophysics doi: 10.1016/j.abb.2020.108297 [Secrete-Pair™ Dual Luminescence Assay Kit]
Zhu, B., et al. (2020). Antagonistic relationship between the unfolded protein response and myocardin‐driven transcription in smooth muscle. Journal of Cellular Physiology doi: 10.1002/jcp.29637 [Secrete-Pair™ Dual Luminescence Assay Kit]
Li, J., et al. (2020). MAOA-mediated reprogramming of stromal fibroblasts promotes prostate tumorigenesis and cancer stemness. Oncogene doi: 10.1038/s41388-020-1217-4 [Secrete-Pair™ Dual Luminescence Assay Kit]
Caracciolo, D., et al. (2020). Exploiting MYC-induced PARPness to target genomic instability in multiple myeloma. Haematologica doi: 10.3324/haematol.2019.240713 [Secrete-Pair™ Dual Luminescence Assay Kit]
Li, P., et al. (2020). Protective Effects of Lixisenatide against Lipopolysaccharide-Induced Inflammation Response in MAC-T Bovine Mammary Epithelial Cells: A Therapeutic Implication in Mastitis. Chemical Research in Toxicology doi: 10.1021/acs.chemrestox.9b00524 [Secrete-Pair™ Dual Luminescence Assay Kit]
Huang, R., et al. (2020). CCL5 derived from tumor-associated macrophages promotes prostate cancer stem cells and metastasis via activating β-catenin/STAT3 signaling. Cell Death & Disease doi: 10.1038/s41419-020-2435-y [Secrete-Pair™ Dual Luminescence Assay Kit]
Chen, S., et al. (2020). Trimethylamine N-Oxide Binds and Activates PERK to Promote Metabolic Dysfunction. Cel Metabolism doi: 10.1016/j.cmet.2019.08.021 [Secrete-Pair™ Dual Luminescence Assay Kit]
Marneros, A.G. (2020). AP-2β/KCTD1 Control Distal Nephron Differentiation and Protect against Renal Fibrosis. Developmental Cell doi: 10.1016/j.devcel.2020.05.026 [Secrete-Pair™ Dual Luminescence Assay Kit]
Makino, E., et al. (2020). Targeting Rad51 as a strategy for the treatment of melanoma cells resistant to MAPK pathway inhibition. Cell Death & Disease doi: 10.1038/s41419-020-2702-y [Secrete-Pair™ Dual Luminescence Assay Kit]
Wu, F., et al. (2020). miR-19b targets pulmonary endothelial syndecan-1 following hemorrhagic shock. Scientific Reports doi: 10.1038/s41598-020-73021-3 [Secrete-Pair™ Dual Luminescence Assay Kit]
Chen, -Y., et al. (2020). Lysine demethylase 2A expression in cancer-associated fibroblasts promotes breast tumour growth. British ournal of Cancer doi: 10.1038/s41416-020-01112-z [Secrete-Pair™ Dual Luminescence Assay Kit]
Le, B.C., et al. (2020). TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment. Cell Reports doi: 10.1016/j.celrep.2020.108221 [Secrete-Pair™ Dual Luminescence Assay Kit]
Jiang, H., et al. (2020). Jagged1-Notch1-deployed tumor perivascular niche promotes breast cancer stem cell phenotype through Zeb1. Nature Communications doi: 10.1038/s41467-020-18860-4 [Secrete-Pair™ Dual Luminescence Assay Kit]
Orzechowska, E.J., et al. (2020). Interplay among p21Waf1/Cip1, MUSASHI-1 and Krüppel-like factor 4 in activation of Bmi1-CreER reserve intestinal stem cells after gamma radiation-induced injury. Scientific Reports doi: 10.1038/s41598-020-75171-w [Secrete-Pair™ Dual Luminescence Assay Kit]
Hamid, S., et al. (2020). Inositol-requiring enzyme-1 regulates phosphoinositide signaling lipids and macrophage growth. EMBO Reports doi: 10.15252/embr.202051462 [Secrete-Pair™ Dual Luminescence Assay Kit]
Byun, J-k., et al. (2020). Inhibition of Glutamine Utilization Synergizes with Immune Checkpoint Inhibitor to Promote Antitumor Immunity .Molecular Cell doi: 10.1016/j.molcel.2020.10.015 [Secrete-Pair™ Dual Luminescence Assay Kit]
Singh, S.R., et al. (2020). A high-throughput screening identifies ZNF418 as a novel regulator of the ubiquitin-proteasome system and autophagy-lysosomal pathway. Autophagy doi: 10.1080/15548627.2020.1856493 [Secrete-Pair™ Dual Luminescence Assay Kit]
Wrobel, N., et al. (2020). mTORC2 Assembly Is Regulated by USP9X-Mediated Deubiquitination of RICTOR. Cell Reports doi: 10.1016/j.celrep.2020.108564 [Secrete-Pair™ Dual Luminescence Assay Kit]

2019

Jiang, Q., et al. (2019). Hyper-Editing of Cell-Cycle Regulatory and Tumor Suppressor RNA Promotes Malignant Progenitor Propagation. Cancer Cell doi: 10.1016/j.ccell.2018.11.017 [Secrete-Pair™ Dual Luminescence Assay Kit]
Floris, A., et al. (2019). Star-related lipid transfer protein 10 (STARD10): a novel key player in alcohol-induced breast cancer progression. Journal of Experimental & Clinical Cancer Research doi: 10.1186/s13046-018-1013-y [Secrete-Pair™ Dual Luminescence Assay Kit]
Arumugam, A., et al. (2019). Silencing growth hormone receptor inhibits estrogen receptor negative breast cancer through ATP-binding cassette sub-family G member 2. Experimental and Molecular Medicine doi: 10.1038/s12276-018-0197-8 [Secrete-Pair™ Dual Luminescence Assay Kit]
Wu, Y.Z, et al. (2019). Dysregulation of miR-431 and target gene FOXA1 in intestinal tissues of infants with necrotizing enterocolitis. The FASEB Journal doi: 10.1096/fj.201801470R [Secrete-Pair™ Dual Luminescence Assay Kit]
Lakshmipathi, J., et al. (2019). Identification of NFAT5 as a transcriptional regulator of the EDN1gene in collecting duct. American Journal of Renal Physiology doi: 10.1152/ajprenal.00509.2018 [Secrete-Pair™ Dual Luminescence Assay Kit]
He, Q., et al. (2019). MiR-206 reduced the malignancy of hepatocellular carcinoma cells in vitro by inhibiting MET and CTNNB1 gene expressions. RSC Advances doi: 10.1039/C8RA09229J [Secrete-Pair™ Dual Luminescence Assay Kit]
Wen, Q., et al. (2019). FoxO3a inhibiting expression of EPS8 to prevent progression of NSCLC: A new negative loop of EGFR signaling. bRioMedicine doi: 10.1016/j.ebiom.2019.01.053 [Secrete-Pair™ Dual Luminescence Assay Kit]
Hecker, M., et al. (2019). A genetic variant associated with multiple sclerosis inversely affects the expression of CD58 and microRNA-548ac from the same gene. PLOS Genetics doi: 10.1371/journal.pgen.1007961 [Secrete-Pair™ Dual Luminescence Assay Kit]
Park, M.K., et al. (2019). PTEN self-regulates through USP11 via the PI3K-FOXO pathway to stabilize tumor suppression. Nature communications doi: 10.1038/s41467-019-08481-x [Secrete-Pair™ Dual Luminescence Assay Kit]
He, L., et al. (2019). Expression, Regulation, and Function of the Calmodulin Accessory Protein PCP4/PEP-19 in Myometrium. Reproductive Sciences doi: 10.1177/1933719119828072 [Secrete-Pair™ Dual Luminescence Assay Kit]
Meng, J., et al. (2019). USP5 promotes epithelial-mesenchymal transition by stabilizing SLUG in hepatocellular carcinoma. Theranostics doi: 10.7150/thno.27654 [Secrete-Pair™ Dual Luminescence Assay Kit]
Beug, S.T., et al. (2019). The transcription factor SP3 drives TNF-α expression in response to Smac mimetics. Science Signaling doi: 10.1126/scisignal.aat9563 [Secrete-Pair™ Dual Luminescence Assay Kit]
Lim, J.P., et al. (2019). Silencing Y-box binding protein-1 inhibits triple-negative breast cancer cell invasiveness via regulation of MMP1 and beta-catenin expression. Cancer Letters doi: 10.1016/j.canlet.2019.03.014 [Secrete-Pair™ Dual Luminescence Assay Kit]
Wu, J., et al. (2019). Reciprocal interaction of HOTAIR and SP1 together enhance the ability of Xiaoji decoction and gefitinib to inhibit EP4 expression. Journal of Ethnopharmacology doi: 10.1016/j.jep.2019.03.027 [Secrete-Pair™ Dual Luminescence Assay Kit]
Scheinber, D.A., et al. (2019). METHOD OF TREATING DISEASES USING KINASE MODULATORS. United States Patent Application 20190077856 [Secrete-Pair™ Dual Luminescence Assay Kit]
Zhao, K., et al. (2019). Inhibition of miR-140-3p or miR-155-5p by antagomir treatment sensitize chordoma cells to chemotherapy drug treatment by increasing PTEN expression. European Journal of Pharmacology doi: 10.1016/j.ejphar.2019.03.034 [Secrete-Pair™ Dual Luminescence Assay Kit]
Dussold, C., et al. (2019). DMP1 prevents osteocyte alterations, FGF23 elevation and left ventricular hypertrophy in mice with chronic kidney disease. Bone Research doi: 10.1038/s41413-019-0051-1 [Secrete-Pair™ Dual Luminescence Assay Kit]
Fan, L., et al. (2019). Sitagliptin protects against hypoxia/reoxygenation (H/R)-induced cardiac microvascular endothelial cell injury. Am J Transl Res 2019;11(4):2099-2107 [Secrete-Pair™ Dual Luminescence Assay Kit]
Sun, L., et al. (2019). Lnc‐NA inhibits proliferation and metastasis in endometrioid endometrial carcinoma through regulation of NR4A1. Journal of Cellular and Molecular Medicine doi: 10.1111/jcmm.14345 [Secrete-Pair™ Dual Luminescence Assay Kit]
Zheng, F., et al. (2019). The repression and reciprocal interaction of DNA methyltransferase 1 and specificity protein 1 contributes to the inhibition of MET expression by the combination of Chinese herbal medicine FZKA decoction and erlotinib. Journal of Ethnopharmacology doi: 10.1016/j.jep.2019.111928 [Secrete-Pair™ Dual Luminescence Assay Kit]
Chen, T-Y., et al. (2019). Determination of Pyruvate Metabolic Fates Modulates Head and Neck Tumorigenesis. Neoplasia doi: 10.1016/j.neo.2019.04.007 [Secrete-Pair™ Dual Luminescence Assay Kit]
Lee, C-M., et al. (2019). Chitinase 1 regulates pulmonary fibrosis by modulating TGF-β/SMAD7 pathway via TGFBRAP1 and FOXO3. Life Science Alliance doi: 10.26508/lsa.201900350 [Secrete-Pair™ Dual Luminescence Assay Kit]
Senfter, D., et al. (2019). High impact of miRNA-4521 on FOXM1 expression in medulloblastoma. Cell Death & Disease doi: 10.1038/s41419-019-1926-1 [Secrete-Pair™ Dual Luminescence Assay Kit]
Liu, H-B., et al. (2019). RNA-Binding Protein IGF2BP2/IMP2 is a Critical Maternal Activator in Early Zygotic Genome Activation. Advanced Science doi: 10.1002/advs.201900295 [Secrete-Pair™ Dual Luminescence Assay Kit]
Nunez, S., et al. (2019). P311, a novel intrinsically disordered protein, regulates adipocyte development. Biochemical and Biophysical Research Communications doi: 10.1016/j.bbrc.2019.05.105 [Secrete-Pair™ Dual Luminescence Assay Kit]
Xie, J., et al. (2019). Cx32 mediates norepinephrine‐promoted EGFR‐TKI resistance in a gap junction‐independent manner in non‐small‐cell lung cancer. Journal of Cellular Physiology doi: 10.1002/jcp.28881 [Secrete-Pair™ Dual Luminescence Assay Kit]
Cheng, W-L., et al. (2019). MicroRNA‐133 suppresses ZFHX3‐dependent atrial remodelling and arrhythmia. Acta physiologica doi: 10.1111/apha.13322 [Secrete-Pair™ Dual Luminescence Assay Kit]
Han, F., et al.(2019). Dopamine D2 receptor modulates Wnt expression and control of cell proliferation. Scientific Reports doi: 10.1038/s41598-019-52528-4 [Secrete-Pair™ Dual Luminescence Assay Kit]
Mazzone, A., et al. (2019), microRNA overexpression in slow transit constipation leads to reduced NaV1.5 current and altered smooth muscle contractility. Gut doi: 10.1136/gutjnl-2019-318747 [Secrete-Pair™ Dual Luminescence Assay Kit]
Wang, S., et al. (2019). XIAOPI Formula Inhibits Breast Cancer Stem Cells via Suppressing Tumor-Associated Macrophages/C-X-C Motif Chemokine Ligand 1 Pathway. Frontiers in Pharmacology doi: 10.3389/fphar.2019.01371 [Secrete-Pair™ Dual Luminescence Assay Kit]
Rivera-Soto, R., et al. (2019). Kaposi’s Sarcoma-associated Herpesvirus Viral Interleukin 6 Signaling Upregulates Integrin Beta 3 Levels and is Dependent on STAT3. Journal of Virology doi: 10.1128/JVI.01384-19 [Secrete-Pair™ Dual Luminescence Assay Kit]
Yu, J-m,., et al. (2019). TRIB3 supports breast cancer stemness by suppressing FOXO1 degradation and enhancing SOX2 transcription. Nature Communications doi: 10.1038/s41467-019-13700-6 [Secrete-Pair™ Dual Luminescence Assay Kit]
Rivera-Soto, R., et al. (2019). Kaposi’s Sarcoma-associated Herpesvirus Viral Interleukin 6 Signaling Upregulates Integrin Beta 3 Levels and is Dependent on STAT3. Journal of Virology doi: 10.1128/JVI.01384-19 [Secrete-Pair™ Dual Luminescence Assay Kit]
Liu, Y-n., e tla. (2019). Acquired resistance to EGFR tyrosine kinase inhibitors is mediated by the reactivation of STC2/JUN/AXL signaling in lung cancer. International Journal of Cancer doi: 10.1002/ijc.32487 [Secrete-Pair™ Dual Luminescence Assay Kit]
Yang, Y.M., et al. (2019). Hyaluronan synthase 2–mediated hyaluronan production mediates Notch1 activation and liver fibrosis. Science Translational Medicine doi: 10.1126/scitranslmed.aat9284 [Secrete-Pair™ Dual Luminescence Assay Kit]
Jiang, L., et al. (2019). Ivermectin reverses the drug resistance in cancer cells through EGFR/ERK/Akt/NF-κB pathway. Journal of Experimental & Clinical Cancer Research doi: 10.1186/s13046-019-1251-7 [Secrete-Pair™ Dual Luminescence Assay Kit]
Xiao, X-G., et al. (2019). miR-665 expression predicts poor survival and promotes tumor metastasis by targeting NR4A3 in breast cancer. Cell Death & Disease doi: 10.1038/s41419-019-1705-z [Secrete-Pair™ Dual Luminescence Assay Kit]
Chen, G., et al. (2019). MiR-148a agomir based targeting of c-Met and Her-3 is able to attenuate EGFR-T790M mutation driven gefitinib and erlotinib resistance in non-small cell lung cancer cells. RSC Advances doi: 10.1039/C8RA10224D [Secrete-Pair™ Dual Luminescence Assay Kit]
Yang, M., et al. (2019). Clockophagy is a novel selective autophagy process favoring ferroptosis. Science Advances doi: 10.1126/sciadv.aaw2238 [Secrete-Pair™ Dual Luminescence Assay Kit]
Liu, H-J., et al. (2019). Rapamycin-upregulated miR-29b promotes mTORC1-hyperactive cell growth in TSC2-deficient cells by downregulating tumor suppressor retinoic acid receptor β (RARβ). Oncogene doi: 10.1038/s41388-019-0957-5 [Secrete-Pair™ Dual Luminescence Assay Kit]

2018

Xiong, K., et al. (2018). MicroRNA‑9 functions as a tumor suppressor and enhances radio‑sensitivity in radio‑resistant A549 cells by targeting neuropilin 1. Oncology Letters doi: 10.3892/ol.2017.7705 [Secrete-Pair™ Dual Luminescence Assay Kit]
Zheng, X., et al. (2018). Dihydromyricetin Ameliorates Nonalcoholic Fatty Liver Disease by Improving Mitochondrial Respiratory Capacity and Redox Homeostasis Through Modulation of SIRT3 Signaling. Antioxidants & Redox Signaling doi: 10.1089/ars.2017.7172 [Secrete-Pair™ Dual Luminescence Assay Kit]
Dang, Y., et al. (2018). MicroRNA-379-5p is associate with biochemical premature ovarian insufficiency through PARP1 and XRCC6. Cell Death & Disease doi: 10.1038/s41419-017-0163-8 [Secrete-Pair™ Dual Luminescence Assay Kit]
Bueno, M., et al. (2018). ATF3 represses PINK1 gene transcription in lung epithelial cells to control mitochondrial homeostasis. Aging Cell doi: 10.1111/acel.12720 [Secrete-Pair™ Dual Luminescence Assay Kit]
Kishire, R., et al. (2018). Use of MicroRNA 375 in Augmenting Stem Cell Based and Endogenous Ischemic Tissue Repair. United States Patent Application 20180008641 [Secrete-Pair™ Dual Luminescence Assay Kit]
Wang, J., et al. (2018). Targeting dual specificity protein kinase TTK attenuates tumorigenesis of glioblastoma. Oncotarget doi: 10.18632/oncotarget.23152 [Secrete-Pair™ Dual Luminescence Assay Kit]
Bao, M., et al. (2018). Long non-coding RNA LINC00657 acting as miR-590-3p sponge to facilitate low concentration oxidized low-density lipoprotein-induced angiogenesis. Molecular Pharmacology doi: 10.1124/mol.117.110650 [Secrete-Pair™ Dual Luminescence Assay Kit]
Zhang, Z., et al. (2018). CRISPR/CAS9 ablation of individual miRNAs from a miRNA family reveals their individual efficacies for regulating cardiac differentiation. Mechanisms of Development doi: 10.1016/j.mod.2018.02.002 [Secrete-Pair™ Dual Luminescence Assay Kit]
Zhang, W., et al. (2018). Androgen receptor/let-7a signaling regulates breast tumor-initiating cells. Oncotarget doi: 10.18632/oncotarget.23196 [Secrete-Pair™ Dual Luminescence Assay Kit]
Mellado-Gil, J.M., et al. (2018). The type 2 diabetes-associated HMG20A gene is mandatory for islet beta cell functional maturity. Cell Death & Disease doi: 10.1038/s41419-018-0272-z [Secrete-Pair™ Dual Luminescence Assay Kit]
Chinnappan, M., et. al. (2018). Network of MicroRNAs Mediate Translational Repression of Bone Morphogenetic Protein Receptor‐2: Involvement in HIV‐Associated Pulmonary Vascular Remodeling. Journal of the American Heart Association doi: 10.1161/JAHA.117.008472 [Secrete-Pair™ Dual Luminescence Assay Kit]
Sinha, M., et al. (2018). Direct conversion of injury-site myeloid cells to fibroblast-like cells of granulation tissue. Nature Communications doi: 10.1038/s41467-018-03208-w [Secrete-Pair™ Dual Luminescence Assay Kit]
Yu, R., et al. (2018). miR‑377 targets CUL4A and regulates metastatic capability in ovarian cancer. International Journal of Molecular Medicine doi: 10.3892/ijmm.2018.3540 [Secrete-Pair™ Dual Luminescence Assay Kit]
Mao, L., et al. (2018). Protective effects of sulforaphane in experimental vascular cognitive impairment: Contribution of the Nrf2 pathway. Journal of Cerebral Blood Flow and Metabolism March 13, 2018 [Secrete-Pair™ Dual Luminescence Assay Kit]
Latonen, L., et al. (2018). Integrative proteomics in prostate cancer uncovers robustness against genomic and transcriptomic aberrations during disease progression. Nature Communications doi: 10.1038/s41467-018-03573-6 [Secrete-Pair™ Dual Luminescence Assay Kit]
Ramalho-Carvalho, J, et al. (2018). A multiplatform approach identifies miR-152-3p as a common epigenetically regulated onco-suppressor in prostate cancer targeting TMEM97. Clinical Epigenetics doi: 10.1186/s13148-018-0475-2 [Secrete-Pair™ Dual Luminescence Assay Kit]
Wang, B., et al. (2018). Sodium butyrate abolishes the degradation of type II collagen in human chondrocytes. Biomedicine & Pharmacotherapy doi: 10.1016/j.biopha.2018.03.062 [Secrete-Pair™ Dual Luminescence Assay Kit]
Armelloni, S., et al. (2018). NeuroD Expression in Podocytes and Interrelationships with Nephrin at Both Nuclear and Cytoplasmic Sites. Cellular Physiology and Biochemistry doi: 10.1159/000488818 [Secrete-Pair™ Dual Luminescence Assay Kit]
Liang, B., et al. (2018). Lycium barbarum polysaccharide protects HSF cells against ultraviolet-induced damage through the activation of Nrf2. Cellular & Molecular Biology Letters doi: 10.1186/s11658-018-0084-2 [Secrete-Pair™ Dual Luminescence Assay Kit]
Bardin, P., et al. (2018). Small RNA and transcriptome sequencing reveal the role of miR‐199a‐3p in inflammatory processes in cystic fibrosis airways. the Journal of Pthology doi: 10.1002/path.5095 [Secrete-Pair™ Dual Luminescence Assay Kit]
Lin, C-H., et al. (2018). MicroRNA-328 inhibits migration and epithelial–mesenchymal transition by targeting CD44 in nasopharyngeal carcinoma cells. OncoTargets and Therapy doi: 10.2147/OTT.S151665 [Secrete-Pair™ Dual Luminescence Assay Kit]
Yang, T., et al. (2018). Brain ischemic preconditioning protects against ischemic injury and preserves the blood-brain barrier via oxidative signaling and Nrf2 activation. Redox Biology doi: 10.1016/j.redox.2018.05.001 [Secrete-Pair™ Dual Luminescence Assay Kit]
Jia, Y., et al. (2018). The novel KLF4/PLAC8 signaling pathway regulates lung cancer growth. Cell Death & Disease doi: 10.1038/s41419-018-0580-3 [Secrete-Pair™ Dual Luminescence Assay Kit]
Xiang, S., et al. (2018). Crosstalk of NF-κB/P65 and LncRNA HOTAIR-Mediated Repression of MUC1 Expression Contribute to Synergistic Inhibition of Castration-Resistant Prostate Cancer by Polyphyllin 1-Enzalutamide Combination Treatment. Cellular Physiology and Biochemistry doi: 10.1159/000490028 [Secrete-Pair™ Dual Luminescence Assay Kit]
Liu, N., et al. (2018). miR-598 acts as a tumor suppressor in human gastric cancer by targeting IGF-1R. OncoTargets and Therapy doi: 10.2147/OTT.S166597 [Secrete-Pair™ Dual Luminescence Assay Kit]
Karthikeyan, A., et al. (2018). Microglial SMAD4 regulated by microRNA-146a promotes migration of microglia which support tumor progression in a glioma environment. Oncotarget doi: 10.18632/oncotarget.25116 [Secrete-Pair™ Dual Luminescence Assay Kit]
Hildebrandt, S., et al,. (2018). Glucocorticoids suppress Wnt16 expression in osteoblasts in vitro and in vivo. Scientific Reports doi: 10.1038/s41598-018-26300-z [Secrete-Pair™ Dual Luminescence Assay Kit]
Ye, D-J., et al. (2018). Discovery of ezrin expression as a potential biomarker for chemically induced ocular irritation using human corneal epithelium cell line and a reconstructed human cornea-like epithelium model. Toxicological Sciences doi: 10.1093/toxsci/kfy134 [Secrete-Pair™ Dual Luminescence Assay Kit]
Lu, Y., et al. (2018). Th9 Cells Represent a Unique Subset of CD4+ T Cells Endowed with the Ability to Eradicate Advanced Tumors. Cancer Cell doi: 10.1016/j.ccell.2018.05.004 [Secrete-Pair™ Dual Luminescence Assay Kit]
Cerro-Herreros, E., et al. (2018). miR-23b and miR-218 silencing increase Muscleblind-like expression and alleviate myotonic dystrophy phenotypes in mammalian models. Nature Communications doi: 10.1038/s41467-018-04892-4 [Secrete-Pair™ Dual Luminescence Assay Kit]
Li, L., et al. (2018). Comparison of multi-lineage differentiation of hiPSCs reveals novel miRNAs that regulate lineage specification. Scientific Reports doi: 10.1038/s41598-018-27719-0 [Secrete-Pair™ Dual Luminescence Assay Kit]
Norcini, M., et al. (2018). Intrathecal Injection of miR-133b-3p or miR-143-3p Prevents the Development of Persistent Cold and Mechanical Allodynia Following a Peripheral Nerve Injury in Rats. Neuroscience doi: 10.1016/j.neuroscience.2018.06.040 [Secrete-Pair™ Dual Luminescence Assay Kit]
Subramani, R., et al. (2018). FOXC1 plays a crucial role in the growth of pancreatic cancer. Oncogenesis doi: 10.1038/s41389-018-0061-7 [Secrete-Pair™ Dual Luminescence Assay Kit]
Tu, C., et al. (2018). Proteomic Analysis of Charcoal-Stripped Fetal Bovine Serum Reveals Changes in the Insulin-like Growth Factor Signaling Pathway. Journal of Proteome Research doi: 10.1021/acs.jproteome.8b00135 [Secrete-Pair™ Dual Luminescence Assay Kit]
Du, L., et al. (2018). MiR-206 is down-regulated and suppresses cell proliferation by targeting FOXP1 in brain gliomas. Int J Clin Exp Pathol 2018;11(7):3405-3415 [Secrete-Pair™ Dual Luminescence Assay Kit]
Xiong, Y., et al. (2018). miR-190 promotes HCC proliferation and metastasis by targeting PHLPP1. Experimental Cell Research doi: 10.1016/j.yexcr.2018.08.008 [Secrete-Pair™ Dual Luminescence Assay Kit]
Guo, X., et al. (2018). Shikimic acid prevents cartilage matrix destruction in human chondrocytes. International Immunopharmacology doi: 10.1016/j.intimp.2018.07.021 [Secrete-Pair™ Dual Luminescence Assay Kit]
Meng, J., et al. (2018). Hsp90β promotes aggressive vasculogenic mimicry via epithelial–mesenchymal transition in hepatocellular carcinoma. Oncogene doi: 10.1038/s41388-018-0428-4 [Secrete-Pair™ Dual Luminescence Assay Kit]
Kim, K.C., et al. (2018). Suppression of metastasis through inhibition of chitinase 3-like 1 expression by miR -125a -3p-mediated up-regulation of USF1. Theranostics doi: 10.7150/ thno .26467 [Secrete-Pair™ Dual Luminescence Assay Kit]
Woo, J.K., et al. (2018). Essential role of Ahnak in adipocyte differentiation leading to the transcriptional regulation of Bmpr1α expression. Cell Death & Disease doi: 10.1038/s41419-018-0873-6 [Secrete-Pair™ Dual Luminescence Assay Kit]
Zhu, B., et al. (2018). Nexilin/NEXN controls actin polymerization in smooth muscle and is regulated by myocardin family coactivators and YAP. Scientific Reports doi: 10.1038/s41598-018-31328-2 [Secrete-Pair™ Dual Luminescence Assay Kit]
Kirchmeyer, M., et al. (2018). Cytokine-mediated modulation of the hepatic miRNome: miR-146b-5p is an IL-6-inducible miRNA with multiple targets. Journal of Leukocyte Biology doi: 0.1002/JLB.MA1217-499RR [Secrete-Pair™ Dual Luminescence Assay Kit]
Liu, X., et al. (2018). A novel lncRNA regulates HCV infection through IFI6. Hepatology doi: 10.1002/hep.30266 [Secrete-Pair™ Dual Luminescence Assay Kit]
Zheng, F., et al. (2018). Inactivation of Stat3 and crosstalk of miRNA155-5p and FOXO3a contribute to the induction of IGFBP1 expression by beta-elemene in human lung cancer. Experimental and Molecular Medicine doi: 10.1038/s12276-018-0146-6 [Secrete-Pair™ Dual Luminescence Assay Kit]
Hourigan, S.T., et al., (2018). The regulation of miRNAs by reconstituted high-density lipoproteins in diabetes-impaired angiogenesis. Scientific Reports doi: 10.1038/s41598-018-32016-x [Secrete-Pair™ Dual Luminescence Assay Kit]
Shen, P., et al. (2018). Metformin blocks MYC protein synthesis in colorectal cancer via mTOR-4EBP-eIF4E and MNK1-eIF4G-eIF4E signaling. Molecular Oncology doi:10.1002/1878-0261.12384 [Secrete-Pair™ Dual Luminescence Assay Kit]
Xiao, Q., et al. (2018). Repression of PDK1- and LncRNA HOTAIR-Mediated EZH2 Gene Expression Contributes to the Enhancement of Atractylenolide 1 and Erlotinib in the Inhibition of Human Lung Cancer Cells. Cellular Physiology and Biochemistry doi: 10.1159/00049349 [Secrete-Pair™ Dual Luminescence Assay Kit]
Zhu, E., et al. (2018). Long noncoding RNA Plnc1 controls adipocyte differentiation by regulating peroxisome proliferator–activated receptor γ. The FASEB Journal doi: 10.1096/fj.201800739RRR [Secrete-Pair™ Dual Luminescence Assay Kit]
Krawczyk. K., et al. (2018). Expression of endothelin type B receptors (EDNRB) on smooth muscle cells is controlled by MKL2, ternary complex factors and actin dynamics. American Journal of Physiology-Cell Physiology doi: 10.1152/ajpcell.00170.2018 [Secrete-Pair™ Dual Luminescence Assay Kit]
Liu, B., et al. (2018). Downregulation of microRNA‑30a in bronchoalveolar lavage fluid from idiopathic pulmonary fibrosis patients. Molecular Medicine Reports doi: 10.3892/mmr.2018.9565 [Secrete-Pair™ Dual Luminescence Assay Kit]
Wen, J., et al. (2018). miR-424 coordinates multilayered regulation of cell cycle progression to promote esophageal squamous cell carcinoma cell proliferation. EBioMedicine doi: 10.1016/j.ebiom.2018.10.043 [Secrete-Pair™ Dual Luminescence Assay Kit]
Ambrozkiewicz, M.C., et al. (2018). Polarity Acquisition in Cortical Neurons Is Driven by Synergistic Action of Sox9-Regulated Wwp1 and Wwp2 E3 Ubiquitin Ligases and Intronic miR-140. Neuron doi: 10.1016/j.neuron.2018.10.008 [Secrete-Pair™ Dual Luminescence Assay Kit]
Huang, D., et al. (2018). An NIR‐II Fluorescence/Dual Bioluminescence Multiplexed Imaging for In Vivo Visualizing the Location, Survival, and Differentiation of Transplanted Stem Cells. Advanced Functional Materials doi: 10.1002/adfm.201806546 [Secrete-Pair™ Dual Luminescence Assay Kit]
Vargas, G., et al. (2018). ERRα promotes breast cancer cell dissemination to bone by increasing RANK expression in primary breast tumors. Oncogene doi: 10.1038/s41388-018-0579-3 [Secrete-Pair™ Dual Luminescence Assay Kit]
Xin, L., et al. (2018). SND1 acts upstream of SLUG to regulate the epithelial–mesenchymal transition (EMT) in SKOV3 cells. The FASEB Journal doi: 10.1096/fj.201801728R [Secrete-Pair™ Dual Luminescence Assay Kit]
Xiang, X., et al. (2018). Ivabradine abrogates TNF-α-induced degradation of articular cartilage matrix. International Immunopharmacology doi: 10.1016/j.intimp.2018.11.035 [Secrete-Pair™ Dual Luminescence Assay Kit]
Yang, J.W., et al. (2018). The mitochondrial chaperone Prohibitin 1 negatively regulates interleukin-8 in human liver cancers. The Journal of Biological Chemistry doi: 10.1074/jbc.RA118.004863 [Secrete-Pair™ Dual Luminescence Assay Kit]
Beug, S.T., et al. (2019). The transcription factor SP3 drives TNF-α expression in response to Smac mimetics. Science Signaling doi: 10.1126/scisignal.aat9563 [Secrete-Pair™ Dual Luminescence Assay Kit]
Chen, J.Y.U., et al. (2019). The C-Terminus of Hepatitis B Virus-encoded X Protein Is Required for Lapatinib Sensitivity in Hepatocellular Carcinoma Cells. Anticancer Research doi: 10.21873/anticanres.13168 [Secrete-Pair™ Dual Luminescence Assay Kit]

2017

Druzd, D., et al. (2017). Lymphocyte Circadian Clocks Control Lymph Node Trafficking and Adaptive Immune Responses. Immunity doi: 10.1016/j.immuni.2016.12.011 [Secrete-Pair™ Dual Luminescence Assay Kit]
Alvarado, A.G., et al. (2017). Glioblastoma Cancer Stem Cells Evade Innate Immune Suppression of Self-Renewal through Reduced TLR4 Expression. Cell Stem Cell doi: 10.1016/j.stem.2016.12.001 [Secrete-Pair™ Dual Luminescence Assay Kit]
Tang, Q., et al. (2017). Emodin Increases Expression of Insulin-Like Growth Factor Binding Protein 1 through Activation of MEK/ERK/AMPKα and Interaction of PPARγ and Sp1 in Lung Cancer. Cellular Physiology and Biochemistry doi: 10.1159/000456281. [Secrete-Pair™ Dual Luminescence Assay Kit]
Dal-Pra, S., et al. (2017). Demethylation of H3K27 Is Essential for the Induction of Direct Cardiac Reprogramming by miR Combo. Circulation Research doi: 10.1161/CIRCRESAHA.116.308741 [Secrete-Pair™ Dual Luminescence Assay Kit]
Cioffi, M., et al. (2017). The miR-25-93-106b cluster regulates tumor metastasis and immune evasion via modulation of CXCL12 and PD-L1. Oncotarget February 17, 2017 [Secrete-Pair™ Dual Luminescence Assay Kit]
Elsafadi, M., et al., (2017). MicroRNA-4739 regulates osteogenic and adipocytic differentiation of immortalized human bone marrow stromal cells via targeting LRP3. Stem Cell Research doi: 10.1016/j.scr.2017.03.001 [Secrete-Pair™ Dual Luminescence Assay Kit]
Sims, E.K., et al. (2017). MicroRNA 21 targets BCL2 mRNA to increase apoptosis in rat and human beta cells. Diabetologia doi: 10.1007/s00125-017-4237-z [Secrete-Pair™ Dual Luminescence Assay Kit]
Lim, J.P., et al. (2017). YBX1 gene silencing inhibits migratory and invasive potential via CORO1C in breast cancer in vitro. BMC Cancer doi: 10.1186/s12885-017-3187-7 [Secrete-Pair™ Dual Luminescence Assay Kit]
Cho, Y.S., et al. (2017). COMPOSITIONS COMPRISING A MITOFUSIN INHIBITOR FOR PROMOTING CELL REPROGRAMMING AND A USE THEREOF United States Patent Application 20170051254 [Secrete-Pair™ Dual Luminescence Assay Kit]
Sun, J., et al. (2017). HMGA2 regulates CD44 expression to promote gastric cancer cell motility and sphere formation. Am J Cancer Res 2017;7(2) :260-274 [Secrete-Pair™ Dual Luminescence Assay Kit]
Mondello, P., et al. (2017). Panobnostat acts synergistically with ibrutinb in diffuse large B cell lymphoma cells with MyD88 L265 mutations. JC Insight doi: doi.org/10.1172 [Secrete-Pair™ Dual Luminescence Assay Kit]
Aldahmash, A., et al. (2017). MicroRNA-4739 regulates osteogenic and adipocytic differentiation of immortalized human bone marrow stromal cells via targeting LRP3. Stem Cell Research doi: 10.1016/j.scr.2017.03.001 [Secrete-Pair™ Dual Luminescence Assay Kit]
Wu, J.J., et al. (2017). Interplay of DNA methyltransferase 1 and EZH2 through inactivation of Stat3 contributes to β-elemene-inhibited growth of nasopharyngeal carcinoma cells. Scientific Reports doi: 10.1038/s41598-017-00626-6 [Secrete-Pair™ Dual Luminescence Assay Kit]
Morel, A. P., et al. (2017). A stemness-related ZEB1–MSRB3 axis governs cellular pliancy and breast cancer genome stability. Nature Medicine doi: 10.1038/nm.4323 [Secrete-Pair™ Dual Luminescence Assay Kit]
Chen, J., et al. (2017). Fas signaling induces stemness properties in colorectal cancer by regulation of Bmi1. Molecular Carcinogenesis doi: 10.1002/mc.22680 [Secrete-Pair™ Dual Luminescence Assay Kit]
Zahedi, F. (2017). Role of Dicer in smooth muscle cells during neointima formation. Ph.D. Thesis, University of Munich [Secrete-Pair™ Dual Luminescence Assay Kit]
Azeem, W., wt al. (2017). An androgen response element driven reporter assay for the detection of androgen receptor activity in prostate cells. PLoS ONE doi: 10.1371/journal.pone.0177861 [Secrete-Pair™ Dual Luminescence Assay Kit]
Li, D., et al. (2017). Hepatic hypoxia-inducible factors inhibit PPARα expression to exacerbate acetamnophen induced oxidative stress and hepatotoxicity. Free Radical Biology and Medicine doi: 10.1016/j.freeradbiomed.2017.06.002 [Secrete-Pair™ Dual Luminescence Assay Kit]
Bala, S., et al. (2017). Alcohol-induced miR-155 and HDAC11 inhibit negative regulators of the TLR4 pathway and lead to increased LPS responsiveness of Kupffer cells in alcoholic liver disease Journal of Leukocyte Biology doi: 10.1189/jlb.3A0716-310R [Secrete-Pair™ Dual Luminescence Assay Kit]
Chen, J.Y., et al. (2017). Hypoxia-induced ADAM 17 expression is mediated by RSK1-dependent C/EBPβ activation in human lung fibroblasts. Molecular Immunology doi: 10.1016/j.molimm.2017.06.029 [Secrete-Pair™ Dual Luminescence Assay Kit]
Qian, H., et al. (2017). MicroRNA-26a inhibits the growth and invasiveness of malignant melanoma and directly targets on MITF gene. Cell Death Discover doi: 10.1038/cddiscovery.2017.28 [Secrete-Pair™ Dual Luminescence Assay Kit]
Thiagarajan, P.S., et al. (2017). STAT3 activation by leptin receptor is essential for TNBC stem cell maintenance. Endocrine-Related Cancer doi: 10.1530/ERC-16-0349 [Secrete-Pair™ Luminescence assay kit]
Madar-Shapiro, L., et al. (2017). Predicting the Risk to Develop Preeclampsia in the First Trimester Combining Promoter Variant -98A/C of LGALS13 (Placental Protein 13), Black Ethnicity, Previous Preeclampsia, Obesity, and Maternal Age. Fetal Diagnosis and Therapy doi: 10.1159/000477933 [Secrete-Pair™ Luminescence assay kit]
Daugaard, I., et al. (2017). miR-151a induces partial EMT by regulating E-cadherin in NSCLC cells. Oncogenesis doi: 10.1038/oncsis.2017.66 [Secrete-Pair™ Dual Luminescence assay kit]
Jiang, Z., et al. (2017). Ribosome profiling reveals translational regulation of mammalian cells in response to hypoxic stress. BMC Genomics doi: 10.1186/s12864-017-3996-8 [Secrete-Pair™ Dual Luminescence assay kit]
Zheng, F., et al. (2017). The enhancement of combination of berberne and metformn in inhibition of DNMT1 gene expression through interplay of SP1 and PDPK1. Journal of Cellular and Mlecular Medicine doi: 10.1111/jcmm.13347 [Secrete-Pair™ Dual Luminescence assay kit]
Zhu, M. (2017). Hyperlipidemia-induced MicroRNA- 155-5p improves β -cell Function by targeting Mafb. Ph.D. Thesis, Universität München [Secrete-Pair™ Dual Luminescence assay kit]
Yang, W.W., et al. (2017). Epiregulin Promotes Lung Metastasis of Salivary Adenoid Cystic Carcinoma. Theranostics doi: 10.7150/ thno .19712 [Secrete-Pair™ Dual Luminescence assay kit]
Wang, D., et al. (2017). Improving transcriptional activity of human cytomegalovirus major immediate-early promoter by mutating NF-κB binding sites. Protein Expression and Purification doi: 10.1016/j.pep.2017.09.008 [Secrete-Pair™ Dual Luminescence assay kit]
Dey, I. and Bradbury, N.A. (2017). Activation of TPA-response element present in human Lemur Tyrosine Kinase 2 (lmtk2) gene increases its expression. Biochemistry and Biophysics Reports doi: 10.1016/j.bbrep.2017.09.006 [Secrete-Pair™ Dual Luminescence assay kit]
Dewi, I.S., et al. (2017). Non-invasive Rejection Surveillance after Heart Transplantation. Ph.D. Thesis, Lund University [Secrete-Pair™ Dual Luminescence assay kit]
Xiao, Q., et al. (2017). Activation of ERK and Mutual Regulation of Stat3 and SP1 Contribute to Inhibition of PDK1 Expression by Atractylenolide-1 in Human Lung Cancer Cells. Cellular Physiology and Biochemistry doi: 10.1159/000484387 [Secrete-Pair™ Dual Luminescence assay kit]
Tang, Q., et al. (2017). Combination of Solamargine and Metformin Strengthens IGFBP1 Gene Expression Through Inactivation of Stat3 and Reciprocal Interaction Between FOXO3a and SP1. Cellular Physiology and Biochemistry doi: 10.1159/000484383 [Secrete-Pair™ Dual Luminescence assay kit]
Hung, S., and Hsu, H. (2017). METHOD FOR INHIBITING SURVIVAL, TUMORIGENESIS AND METASTASIS OF CANCER CELLS AND/OR CANCER STEM CELLS. United States Patent Application 20170304386 [Secrete-Pair™ Dual Luminescence assay kit]
Singh, B.K., et al. (2017). Anti-melanogenic effect of Prunus davidiana extract in melan-a melanocyte through regulation of OCA-2, TRP-1 and tyrosinase. Korean Journal of Chemical Engineering doi: 10.1007/s11814-017-0241-8 [Secrete-Pair™ Dual Luminescence assay kit]
Ma, F., et al. (2017). MiR-361-5p inhibits glycolytic metabolism, proliferation and invasion of breast cancer by targeting FGFR1 and MMP-1. Journal of Experimental & Clinical Cancer Research doi: 10.1186/s13046-017-0630-1 [Secrete-Pair™ Dual Luminescence assay kit]
Martinez-Barquero, V., et al. (2017). Are IL18RAP gene polymorphisms associated with body mass regulation? A cross-sectional study. BMJ Open doi: 10.1136/bmjopen-2017-017875 [Secrete-Pair™ Dual Luminescence assay kit]
Sun, J., et al. (2017). MicroRNA-4465 suppresses tumor proliferation and metastasis in non-small cell lung cancer by directly targeting the oncogene EZH2. Biomedicine and Pharmacotherapy doi: 10.1016/j.biopha.2017.11.070 [Secrete-Pair™ Dual Luminescence assay kit]
Xiang, S.T., et al. (2017). HOTAIR-mediated reciprocal regulation of EZH2 and DNMT1 contribute to polyphyllin I-inhibited growth of castration-resistant prostate cancer cells in vitro and in vivo. Biochimica et Biophysica Acta (BBA) – General Subjects doi: 10.1016/j.bbagen.2017.12.001 [Secrete-Pair™ Dual Luminescence assay kit]
Vychytilova-Faltejskova,P., et al. (2017). MiR-215-5p is a tumor suppressor in colorectal cancer targeting EGFR ligand epiregulin and its transcriptional inducer HOXB9. Oncogenesis doi: 10.1038/s41389-017-0006-6 [Secrete-Pair™ Dual Luminescence assay kit]
Jiang, N., et al. (2017). YAP1 regulates prostate cancer stem cell-like characteristics to promote castration resistant growth. Oncotarget doi: 10.18632/oncotarget.23014 [Secrete-Pair™ Dual Luminescence assay kit]
Hussein, H.A.M., et al. 2017). miRNA-36 inhibits KSHV, EBV, HSV-2 infection of cells via stifling expression of interferon induced transmembrane protein 1 (IFITM1). Scientific Reports doi: 10.1038/s41598-017-18225-w [Secrete-Pair™ Dual Luminescence assay kit]
Xiong, K., et al. (2017). MicroRNA‑9 functions as a tumor suppressor and enhances radio‑sensitivity in radio‑resistant A549 cells by targeting neuropilin 1. Oncology Letters doi: 10.3892/ol.2017.7705 [Secrete-Pair™ Dual Luminescence Assay Kit]
Frith, J.E., et al. (2018). Mechanically-sensitive miRNAs bias human mesenchymal stem cell fate via mTOR signalling. Nature Communications doi: 10.1038/s41467-017-02486-0 [Secrete-Pair™ Dual Luminescence Assay Kit]

2016

Leow, SC. et al. (2016) The transcription factor SOX6 contributes to the developmental origins of obesity by promoting adipogenesis. Development,doi: 10.1242/dev.131573. [Secrete-Pair ™ Gaussia Luciferase Dual Assay Kit ]
Neutzner, Albert, Josef Flammer, and Alice Huxley (2016). “ARTIFICIAL TRANSCRIPTION FACTORS ENGINEERED TO OVERCOME ENDOSOMAL ENTRAPMENT.” U.S. Patent No. 20,160,046,682. 18 Feb. 2016. [Secrete-Pair ™ Gaussia Luciferase Dual Assay Kit ]
Yan, K. (2016). NeuroD family transcription factors regulate corpus callosum formation and cell differentiation during cerebral cortical development (Doctoral dissertation, Freie Universität Berlin) [Secrete-Pair ™ Gaussia Luciferase Dual Assay Kit ]
Bento, Carla F., et al. (2016) The Parkinson/’s disease-associated genes ATP13A2 and SYT11 regulate autophagy via a common pathway. Nature Communications doi:10.1038/ncomms11803 [Secrete-Pair ™ Gaussia Luciferase Dual Assay Kit ]
Liu, Chen-Chi, et al. (2016) Suspension survival mediated by PP2A-STAT3-Col XVII determines tumour initiation and metastasis in cancer stem cells. Nature Communications doi:10.1038/ncomms11798 [Secrete-Pair ™ Gaussia Luciferase Dual Assay Kit ]
Fleyshman, Daria, et al. (2016) ARTIK-52 induces replication-dependent DNA damage and p53 activation exclusively in cells of prostate and breast cancer origin. Cell Cycle doi: 10.1080/15384101.2015.1127478 [Secrete-Pair ™ Gaussia Luciferase Dual Assay Kit ]
Mattinzoli, Deborah, et al. (2016) FGF23-regulated production of Fetuin-A (AHSG) in osteocytes. Bone doi: 10.1016/j.bone.2015.10.008 [Secrete-Pair ™ Gaussia Luciferase Dual Assay Kit ]
Khan, Shahid Y., et al. (2016) FOXE3 contributes to Peters anomaly through transcriptional regulation of an autophagy-associated protein termed DNAJB1. Nature communications doi:10.1038/ncomms10953 [Secrete-Pair ™ Gaussia Luciferase Dual Assay Kit ]
Mao, Cy, et al. (2016) Double-edged-sword effect of IL-1β on the osteogenesis of periodontal ligament stem cells via crosstalk between the NF-κB, MAPK and BMP/Smad signaling pathways. Cell Death & Disease doi:10.1038/cddis.2016.204 [Secrete-Pair ™ Gaussia Luciferase Dual Assay Kit ]
Chen, Jhen-Yu, et al. (2016) HBx sensitizes hepatocellular carcinoma cells to lapatinb by up-regulating ErbB3. Oncotarget doi: 10.18632/oncotarget.6337 [Secrete-Pair ™ Gaussia Luciferase Dual Assay Kit]
Dou, Yun-De, et al. (2016) STMN1 Promotes Progesterone Production Via StAR Up-regulation in Mouse Granulosa Cells. Scientific reports 6doi:10.1038/srep26691 [Secrete-Pair ™ Gaussia Luciferase Dual Assay Kit]
Lee, Hyunkyung, et al. (2016) Genome-wide identification of target genes for miR-204 and miR-211 identifies their proliferation stimulatory role in breast cancer cells. Scientific reports doi: 10.1038/srep25287 [Secrete-Pair ™ Gaussia Luciferase Dual Assay Kit]
Li, Na, et al. (2016) miR-182 Modulates Myocardial Hypertrophic Response Induced by Angiogenesis in Heart. Scientific reports oi: 10.1038/srep21228 [Secrete-Pair ™ Gaussia Luciferase Dual Assay Kit]
Fujii, Tomomi, et al. (2016) MicroRNA-331-3p Suppresses Cervical Cancer Cell Proliferation and E6/E7 Expression by Targeting NRP2. International Journal of Molecular Sciences doi:10.3390/ijms17081351 [Secrete-Pair ™ Gaussia Luciferase Dual Assay Kit]
Akhtar, Nahid, Anil Kumar Singh, and Salahuddin Ahmed. (2016) MicroRNA-17 Suppresses TNF-α Signaling by Interfering with TRAF2 and cIAP2 Association in Rheumatoid Arthritis Synovial Fibroblasts. The Journal of Immunology doi: 10.4049/â€‹jimmunol.1600360 [Secrete-Pair ™ Gaussia Luciferase Dual Assay Kit]
Nakajima, Syo, et al. (2016) Fungal-derived neoechinuln B as a novel antagonist of liver X receptor, identified by chemical genetics using hepatitis C virus cell culture system. Journal of Virology doi: 10.1128/JVI.00856-16 [Secrete-Pair ™ Gaussia Luciferase Dual Assay Kit]
Olave, Nelida, et al. (2016) Regulation of alveolar septation by microRNA-489. American Journal of Physiology-Lung Cellular and Molecular Physiology doi: 10.1152/ajplung.00145.2015 [Secrete-Pair ™ Gaussia Luciferase Dual Assay Kit]
Dahiya, Neetu, et al. (2016) miR-570 interacts with mitochondrial ATPase subunit g (ATP5L) encoding mRNA in stored platelets. Platelets doi: 10.1080/09537104.2016.1203405 [Secrete-Pair ™ Gaussia Luciferase Dual Assay Kit]
Grimm, Marcus Otto, et al. (2016) Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) increase Aβ-degradation by affecting insulin-degrading enzyme (IDE). Biochemistry and Cell Biology doi: 10.1139/bcb-2015-0149 [Secrete-Pair ™ Gaussia Luciferase Dual Assay Kit]
Zhou, Jun-Hao, et al. (2016) MicroRNA-27a-mediated repression of cysteine-rich secretory protein 2 translation in asthenoteratozoospermic patients. Asian journal of andrology (2016). [Secrete-Pair ™ Gaussia Luciferase Dual Assay Kit]
Wu, Lina, et al. (2016) MicroRNA-27a Induces Mesangial Cell Injury by Targeting of PPARγ, and its In Vivo Knockdown Prevents Progression of Diabetic Nephropathy. Scientific reports doi: 10.1038/srep26072 [Secrete-Pair ™ Gaussia Luciferase Dual Assay Kit]
Ye, Shuâ€Biao, et al. (2016) Exosomal miRâ€24â€3p impedes Tâ€cell function by targeting FGF11 and serves as a potential prognostic biomarker for nasopharyngeal carcinoma. The Journal of Pathology doi: 10.1002/path.4781 [Secrete-Pair ™ Gaussia Luciferase Dual Assay Kit]
Zhang, Zhenfeng, et al. (2016) BET Bromodomain Inhibition as a Therapeutic Strategy in Ovarian Cancer by Downregulating FoxM1. Theranostics doi: 10.7150/thno.13178 [Secrete-Pair ™ Gaussia Luciferase Dual Assay Kit]
Li, Longmei, et al. (2016) Inhibition of EZH2 via activation of SAPK/JNK and reduction of p65 and DNMT1 as a novel mechanism in inhibition of human lung cancer cells by polyphyllin I. Journal of Experimental & Clinical Cancer Research doi: 10.1186/s13046-016-0388-x [Secrete-Pair ™ Gaussia Luciferase Dual Assay Kit]
Sysol, Justin R., Viswanathan Natarajan, and Roberto F. Machado. (2016) PDGF Induces SphK1 Expression via Egr-1 to Promote Pulmonary Artery Smooth Muscle Cell Proliferation. American Journal of Physiology-Cell Physiology doi: 10.1152/ajpcell.00059.2016 [Secrete-Pair ™ Gaussia Luciferase Dual Assay Kit]
Zhao, Nan, et al. (2016) miR-27a-3p suppresses tumor metastasis and VM by down-regulating VE-cadherin expression and inhibiting EMT: an essential role for Twist-1 in HCC. Scientific reports doi: 10.1038/srep23091 [Secrete-Pair ™ Gaussia Luciferase Dual Assay Kit]
Tauseef, Mohammad, et al. (2016) Transient receptor potential channel 1 maintains adherens junction plasticity by suppressing sphingosine kinase 1 expression to induce endothelial hyperpermeability. The FASEB Journal doi: 10.1096/fj.15-275891 [Secrete-Pair ™ Gaussia Luciferase Dual Assay Kit]
Gujar, Ravindra, et al. (2016) c-Src Suppresses Dendritic Cell Antitumor Activity via T Cell Ig and Mucin Protein-3 Receptor. The Journal of Immunology doi: 10.4049/â€‹jimmunol.1600104 [Secrete-Pair ™ Gaussia Luciferase Dual Assay Kit]
Yang, LiJun, et al. (2016) Inter-regulation of IGFBP1 and FOXO3a unveils novel mechanism in ursolic acid-inhibited growth of hepatocellular carcinoma cells. Journal of Experimental & Clinical Cancer Research doi: 10.1186/s13046-016-0330-2 [Secrete-Pair ™ Gaussia Luciferase Dual Assay Kit]
Tang, Qing, et al. (2016) Emodn increases expression of insulin-like growth factor binding protein 1 through activation of MEK/ERK/AMPKα and interaction of PPARγ and Sp1 in lung cancer. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease doi: 10.1016/j.bbadis.2016.09.005 [Secrete-Pair ™ Gaussia Luciferase Dual Assay Kit]
Alderman, Christopher, et al. (2016) MicroRNA-15a inhibits the growth and invasiveness of malignant melanoma and directly targets on CDCA4 gene. Tumor Biology doi: 10.1007/s13277-016-5271-z [Secrete-Pair ™ Gaussia Luciferase Dual Assay Kit]
Bao, Mei-hua, et al. (2016) NF-κB-Regulated miR-99a Modulates Endothelial Cell Inflammation. Mediators of Inflammation 2016 doi: 10.1155/2016/5308170 [Secrete-Pair ™ Gaussia Luciferase Dual Assay Kit]
Fujii, T., et al. (2016). MicroRNA-331-3p Suppresses Cervical Cancer Cell Proliferation and E6/E7 Expression by Targeting NRP2. International Journal of Molecular Sciences doi: 10.3390/ijms17081351 [Secrete-Pair Dual™ Luminescence Assay Kit]
Wang, J., et al. (2016). MiR-29a Regulates Radiosensitivity in Human Intestinal Cells by Targeting PTEN Gene. Radiation Research doi: 10.1667/RR14428.1[Secrete-Pair™ Dual Luminescence Assay Kit]
Rehman, M., et al. (2016). PlexinD1 Is a Novel Transcriptional Target and Effector of Notch Signaling in Cancer Cells. PLoS ONE doi: 10.1371/journal.pone.0164660 [Secrete-Pair™ Dual Luminescence Assay Kit]
Li, L., et al. (2016). Chinese herbal medicine Fuzheng Kang-Ai decoctin sensitized the effect of gefitinb on inhibition of human lung cancer cells through inactivating PI3-K/Akt -mediated suppressing MUC1 expression. Journal of Ethnopharmacology doi: 10.1016/j.jep.2016.10.077 [Secrete-Pair™ Dual Luminescence Assay Kit]
Ashouri, A., et al. (2016). Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events. Nature Communications doi: 10.1038/ncomms13197 [Secrete-Pair™ Dual Luminescence Assay Kit]
Romero, M., et al. (2016). Primary mediastinal large B-cell lymphoma: transcriptional
regulation by miR-92a through FOXP1 targeting. Onctotarget October 28, 2016 [Secrete-Pair™ Dual Luminescence Assay Kit]
Chu, Q., et al. (2016). Extracellular serglycin upregulates the CD44 receptor in an autocrine manner to maintain self-renewal in nasopharyngeal carcinoma cells by reciprocally activating the MAPK/β-catenin axis. Cell Death and Disease doi: 10.1038/cddis.2016.287 [Secrete-Pair™ Dual Luminescence Assay Kit]
Cerro-Herreros, E., et al. (2016). Derepressing muscleblind expression by miRNA sponges ameliorates myotonic dystrophy-like phenotypes in Drosophila. Scientifc Reports doi: 10.1038/srep36230 [Secrete-Pair™ Dual Luminescence Assay Kit]
Xiang, S., et al. (2016). Activation of AMPKα mediates additive effects of solamargne and metformn on suppressing MUC1 expression in castration-resistant prostate cancer cells. Scientific Reports doi:10.1038/srep36721 [Secrete-Pair™ Dual Luminescence Assay Kit]
Holler, et al. (2016). Trehalose upregulates progranulin expression in human and mouse models of GRN haploinsufficiency: a novel therapeutic lead to treat frontotemporal dementia. Molecular Neurodegeneration doi: 10.1186/s13024-016-0114-3 [Secrete-Pair™ Dual Luminescence Assay Kit]
Meerson, A., et al. (2016). Leptin and insulin up-regulate miR-4443 to suppress NCOA1 and TRAF4, and decrease the invasiveness of human colon cancer cells. BMC Cancer doi: 10.1186/s12885-016-2938-1 [Secrete-Pair™ Dual Luminescence Assay Kit]
Revandkar, A., et al. (2016). Inhibition of Notch pathway arrests PTEN-deficient advanced prostate cancer by triggering p27-driven cellular senescence. Nature Communications doi: 10.1038/ncomms13719 [Secrete-Pair™ Dual Luminescence Assay Kit]
Xie, X., et al. (2016). c-Jun N-terminal kinase promotes stem cell phenotype in triple-negative breast cancer through upregulation of Notch1 via activation of c-Jun. Oncogene doi: 10.1038/onc.2016.417 [Secrete-Pair™ Dual Luminescence Assay Kit]