View selected publications citing GeneCopoeia’s miTarget™ 3’UTR clones from the recent literature
2024
- Wang, Y., et al. (2024). KLF4 Suppresses the Progression of Hepatocellular Carcinoma by Reducing Tumor ATP Synthesis through Targeting the Mir-206/RICTOR Axis. Int J Mol Sci. DOI: 10.3390/ijms25137165 [miTarget™ miRNA 3′ UTR clone targeting RICTOR, Cat. No. HmiT006478-MT06]
- Xu, F., et al. (2024). Tryptophan As a New Member of RNA‐Induced Silencing Complexes Prevents Colon Cancer Liver Metastasis. Adv Sci (Weinh). DOI: 10.1002/advs.202307937 [miTarget™ 3′ UTR miRNA Target Clone vector, Cat. No. pEZX‐MT05‐Gluc]
- Arora, L., et al. (2024). Hypoxia‐induced miR‐210‐3p expression in lung adenocarcinoma potentiates tumor development by regulating CCL2 mediated monocyte infiltration. Mol Oncol. DOI: 10.1002/1878-0261.13260 [miTarget™ miRNA 3′ UTR target expression clone for Human CCL2]
- Li, S., et al. (2024). Renal ischaemia-reperfusion injury is promoted by transcription factor NF-kB p65; which inhibits TRPC6 expression by activating miR-150. Clin Hemorheol Microcirc. DOI: 10.3233/CH-231979 [miTarget™ miRNA 3′ UTR clone targeting TRPC6]
- Anastasio, C., et al. (2024). MiR-148a-3p/SIRT7 Axis Relieves Inflammatory-Induced Endothelial Dysfunction. Int J Mol Sci. DOI: 10.3390/ijms25105087 [miTarget™ miRNA 3′ UTR clone targeting SIRT7; miRNA Target clone control vector for pEZX-MT06]
- Chen, Y., et al. (2024). MiR-106a-5p targets PFKFB3 and improves sepsis through regulating macrophage pyroptosis and inflammatory response. J Biol Chem. DOI: 10.1016/j.jbc.2024.107334 [miTarget™ miR-106a-5p miRNA 3′ UTR clone]
- Tanaka, L.Y., et al. (2024). Disturbed flow regulates protein disulfide isomerase A1 expression via microRNA-204. Front Physiol. DOI: 10.3389/fphys.2024.1327794 [Luc-Pair™ Firefly Luciferase HS Assay Kit; Luc-Pair™ Duo-Luciferase HS Assay Kit; miTarget™ miRNA 3′ UTR]
- Yang, X., et al. (2024). circRNA_8521 promotes Senecavirus A infection by sponging miRNA-324 to regulate LC3A. Vet Res. DOI: 10.1186/s13567-024-01291-0 [OMICSLINK™ Human circ_8521 ORF expression clone; LC3A 3’UTR luciferase reporter clone pEZX-MT06]
- Kaurani, L., et al. (2024). Regulation of Zbp1 by miR-99b-5p in microglia controls the development of schizophrenia-like symptoms in mice. EMBO J. DOI: 10.1038/s44318-024-00067-8 [miTarget™ miRNA 3′ UTR clone targeting Zbp1]
- Turkowski, K., et al. (2024). miR-147b mediated suppression of DUSP8 promotes lung cancer progression. Oncogene. DOI: 10.1038/s41388-024-02969-7 [ACTB, FGF14 3’UTR luciferase reporter clones, Cat. No.HmiT016381-MT06, HmiT088501-MT06]
- Liu, X., et al. (2024). DNA methylation of microRNA-365-1 induces apoptosis of hair follicle stem cells by targeting DAP3. Noncoding RNA Res. DOI: 10.1016/j.ncrna.2024.03.001 [DAP3 3′ UTR luciferase reporter Clone]
- Jesús Morillo-Bernal, et al. 2024.HuR (ELAVL1) Stabilizes SOX9 mRNA and Promotes Migration and Invasion in Breast Cancer Cells. Cancers (Basel).DOI:10.3390/cancers16020384[miTarget™ Human SOX9 miRNA 3′ UTR target clone and control plasmid, Cat. No.HmiT127361-MT06]
2023
- Katharina Jonas, et al. 2023. MiR-4646-5p Acts as a Tumor-Suppressive Factor in Triple Negative Breast Cancer and Targets the Cholesterol Transport Protein GRAMD1B. Noncoding RNA. DOI: 10.3390/ncrna10010002 [miTarget™ miRNA 3′ UTR clone targeting GRAMD1B]
- Jiyeon Ock, et al. 2023.MicroRNA-148a-3p in pericyte-derived extracellular vesicles improves erectile function in diabetic mice by promoting cavernous neurovascular regeneration. BMC Urol. DOI:10.1186/s12894-023-01378-4[miTarget™ miRNA 3′ UTR clone targeting PDK4 and control; Luc-Pair™ Duo-Luciferase HS Assay Kit]
- Xiuyan Zhang, et al. 2023.miR-181a plays the tumor-suppressor role in chronic myeloid leukemia CD34 + cells partially via SERPINE1. Cell Mol Life Sci.DOI:10.1007/s00018-023-05036-8[miTarget™ miRNA 3′ UTR clone targeting SERPINE1 and control]
- Motofumi Kumazoe, et al. 2023.miR-12135 ameliorates liver fibrosis accompanied with the downregulation of integrin subunit alpha 11. iScience. DOI:10.1016/j.isci.2023.108730[miTarget™ miRNA 3′ UTR clone targeting ITGA11 and control]
- Wu, C., et al. (2023). Pancreatic cancer cells upregulate LPAR4 in response to isolation stress to promote an ECM-enriched niche and support tumor initiation. Nat Cell Biol. doi: 10.1038/s41556-022-01055-y [miTarget™ miRNA 3′ UTR target clone and control plasmid]
- Zhang, Y., et al. (2023). Adipose-derived exosomal miR-421 targets CBX7 and promotes metastatic potential in ovarian cancer cells. J Ovarian Res. doi: 10.1186/s13048-023-01312-0 [miTarget™ CBX7, CBX7 3′ UTR miRNA Target Clone; Secrete-Pair ™ Dual Luminescence Assay]
- Winkler, I., et al. (2023). MicroRNA-92a–CPEB3 axis protects neurons against inflammatory neurodegeneration. Sci Adv. doi: 10.1126/sciadv.adi6855 [miTarget™ Cpeb3 3′UTR miRNA Target Clones]
- Zhang, J., et al. (2023). Electroacupuncture Relieves HuR/KLF9-Mediated Inflammation to Enhance Neurological Repair after Spinal Cord Injury. eNeuro. doi: 10.1523/ENEURO.0190-23.2023 [miTarget™ KLF9 3′ UTR miRNA Target Clone]
- Zheng, F., et al. (2023). MiR-124-3p mediates gastric cancer cell ferroptosis induced by an anti-cancer drug polyphyllin I. Front Pharmacol. doi: 10.3389/fphar.2023.1285799 [MiTarget™ MicroRNA 3′ UTR Clone; Luc-Pair™ Duo-Luciferase HS Assay Kit]
- Korde, A., et al. (2023). MicroRNA-1 protects the endothelium in acute lung injury. JCI Insight. doi: 10.1172/jci.insight.164816 [miTarget™ Angpt2 3′ UTR Clone; Luc-Pair™ Duo-Luciferase HS Assay Kit]
- Islam, M.O., et al. (2023). Smoking induces WEE1 expression to promote docetaxel resistance in esophageal adenocarcinoma. Mol Ther Oncolytics. doi: 10.1016/j.omto.2023.08.012 [miTarget™ WEE1 3′ UTR miRNA Target Clone]
- Veys, C., et al. (2023). MiR-4270 acts as a tumor suppressor by directly targeting Bcl-xL in human osteosarcoma cells. Front Oncol. doi: 10.3389/fonc.2023.1220459 [miTarget™ BCL2, BCL2L1, MCL1 3′ UTR miRNA Target Clones; Secrete-Pair™ Dual Luminescence Assay Kit]
- Littleton, S.H., et al. (2023). Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3’ UTR of FAIM2. bioRxiv. doi: 10.1101/2023.08.21.553157 [miTarget™ FAIM2 3′ UTR miRNA Target Clone; GLuc-ON™ FAIM2, LIMA1, RACGAP1 promoter reporter clones]
- Nakashiro, K., et al. (2023). MicroRNA-1289 Functions as a Novel Tumor Suppressor in Oral Squamous Cell Carcinoma. Cancers (Basel). doi: 10.3390/cancers15164138 [miTarget™ 3′ UTR miRNA Target Clone]
- Martino, E., et al. (2023). MiR-15b-5p and PCSK9 inhibition reduces lipopolysaccharide-induced endothelial dysfunction by targeting SIRT4. Cell Mol Biol Lett. doi: 10.1186/s11658-023-00482-5 [miTarget™ 3′ UTR miRNA Target Clone]
- Yang, Q., et al. (2023). N4‐Acetylcytidine Drives Glycolysis Addiction in Gastric Cancer via NAT10/SEPT9/HIF‐1α Positive Feedback Loop. Advanced Science doi: 10.1002/advs.202300898 [Lenti-Pac™ HIV Expression Packaging Kit; OMICSLINK™ lentiviral shRNA clone; miTarget™ 3′ UTR Clone; Luc-Pair™ Duo-Luciferase HS Assay Kit]
- Gong, H., et al. (2023). miR-146a impedes the anti-aging effect of AMPK via NAMPT suppression and NAD+/SIRT inactivation. Sig Transduct Target Ther doi: 10.1038/s41392-022-00886-3 [All-in-One™ miRNA qRT-PCR detection kit; miExpress™ inhibitor clone; miTarget™ 3′ UTR miRNA Target Clones]
- Li, F., et al. (2023). Reanalysis of ribosome profiling datasets reveals a function of rocaglamide A in perturbing the dynamics of translation elongation via eIF4A. Nat Commun doi: 10.1038/s41467-023-36290-w [miTarget™ 3′ UTR miRNA Target Clones]
- Wei, J., et al. (2023). Targeting REGNASE-1 programs long-lived effector T cells for cancer therapy. Nature doi: 10.1038/s41586-019-1821-z [miTarget™ mouse Batf, Il2 and Il4 3′ UTR miRNA Target Clones; Luc-Pair™ Duo-Luciferase Assay Kits 2.0]
- Wischmann, F-J., et al. (2023). Tumor suppressor miR-218 directly targets epidermal growth factor receptor (EGFR) expression in triple-negative breast cancer; sensitizing cells to irradiation. J Cancer Res Clin Oncol doi: 10.1007/s00432-023-04750-x [Secrete-Pair™ Dual Luminescence Assay Kit; miTarget™ 3′ UTR Clone]
- Vyas, H., et al. (2023). miR34a-5p impedes CLOCK expression in chronodisruptive C57BL/6J mice and potentiates pro-atherogenic manifestations. PLoS One doi: 10.1371/journal.pone.0283591 [Secrete-Pair™ Dual Luminescence Assay Kit; miTarget™ 3′ UTR Clone]
- Tong, Y., et al. (2023). Programming inactive RNA-binding small molecules into bioactive degraders. Nature doi: 10.1038/s41586-023-06091-8 [miExpress™ miRNA precursor clone; miTarget™ 3′ UTR Clone]
- Murray, M.J., et al. (2023). In silico interrogation of the miRNAome of infected hematopoietic cells to predict processes important for human cytomegalovirus latent infection. J Biol Chem doi: 10.1016/j.jbc.2023.104727 [miTarget™ 3′ UTR Clone and control]
- Song. M., et al (2023). circIFNGR2 regulating ankylosing spondylitis-associated inflammation through macrophage polarization. iScience doi: 10.1016/j.isci.2023.107325 [miTarget™ 3′ UTR Clone; miTarget™ 3′ UTR miRNA Target Clones; Luc-Pair™ Duo-Luciferase HS Assay Kit]
- Liu, J., et al. (2023). miR‑137 is a diagnostic tumor‑suppressive miRNA that targets SPHK2 to promote M1‑type tumor‑associated macrophage polarization. Exp Ther Med doi: 10.3892/etm.2023.12096 [miTarget™ SPHK2-3′ UTR miRNA Target Clones]
- Lee, B.B., et al. (2023). Metformin regulates expression of DNA methyltransferases through the miR-148/-152 family in non-small lung cancer cells. Clin Epigenetics doi: 10.1186/s13148-023-01466-0 [miTarget™ DNMT1 3′ UTR Clone; miRNA Target clone control vector for pEZX-MT06]
- Jia, J., et al. (2023). LncRNA DANCR Enhances Angiogenesis to Promote Melanoma Progression Via Sponging miR-5194. J Cancer doi: 10.7150/jca.81723 [DANCR UTR clone]
- Yan, R., et al. (2023). miR-137–LAPTM4B regulates cytoskeleton organization and cancer metastasis via the RhoA-LIMK-Cofilin pathway in osteosarcoma. Oncogenesis doi: 10.1038/s41389-023-00471-5 [miTarget™ LAPTM4B10 3′ UTR Clone and its negative Ctrl]
- D’Onofrio, N., et al. (2023). MiR-27b attenuates mitochondrial oxidative stress and inflammation in endothelial cells. Redox Biol doi: 10.1016/j.redox.2023.102681 [miTarget™ FOXO1 3′ UTR miRNA Target Clones; miRNA Target clone control vector for pEZX-MT06]
- Fan, R., et al. (2023). Porphyromonas gingivalis Outer Membrane Vesicles Promote Apoptosis via msRNA-Regulated DNA Methylation in Periodontitis. Microbiol Spectr doi: 10.1128/spectrum.03288-22 [miTarget™ CBX5 3′ UTR Clone]
- Dykxhoorn, D.M., et al. (2023). MicroRNA-423-5p Mediates Cocaine-Induced Smooth Muscle Cell Contraction by Targeting Cacna2d2. Int J Mol Sci doi: 10.3390/ijms24076584 [pEZX-MT05 vector; miTarget™ Cacna2d2 3′ UTR Clone; Secrete-Pair™ Dual Luminescence Assay Kit]
- Sun, B., et al. (2023). Engineered induced-pluripotent stem cell derived monocyte extracellular vesicles alter inflammation in HIV humanized mice. Extracell Vesicles Circ Nucl Acids doi: 10.20517/evcna.2022.11 [miTarget™ 3′ UTR Clone; Secrete-Pair™ Dual Luminescence Assay Kit]
- Mongiorgi, S., et al. (2023). A miRNA screening identifies miR-192-5p as associated with response to azacitidine and lenalidomide therapy in myelodysplastic syndromes. Clin Epigenetics doi: 10.1186/s13148-023-01441-9 [miTarget™ BCL2-3′ UTR miRNA Target Clones; Luc-Pair™ Duo-Luciferase Assay Kit 2.0]
2022
- Xie, T., et al. (2022). CircSMARCC1 facilitates tumor progression by disrupting the crosstalk between prostate cancer cells and tumor-associated macrophages via miR-1322/CCL20/CCR6 signaling. Mol Cancer doi: 10.1186/s12943-022-01630-9 [Luc-Pair™ Duo-Luciferase HS Assay Kit; miTarget™ 3′ UTR Clone]
- Bogusławska, D.M., et al. (2022). A rare mutation (p.F149del) of the NT5C3A gene is associated with pyrimidine 5′-nucleotidase deficiency. Cell Mol Biol Lett doi: 10.1186/s11658-022-00405-w [miTarget™ NT5C3A wild tyoe and mutant 3′ UTR clones]
- Fan, C., et al. (2022). MiR-137-mediated negative relationship between LGR4 and RANKL modulated osteogenic differentiation of human adipose-derived mesenchymal stem cells. Genet Mol Biol doi: 10.1590/1678-4685-GMB-2021-0332 [miTarget™ 3′ UTR miRNA Target Clones]
- Pandeya, A., et al. (2022). Hcmv-miR-UL148D regulates the staurosporine-induced apoptosis by targeting the Endoplasmic Reticulum to Nucleus signaling 1(ERN1). PLoS One doi: 10.1371/journal.pone.0275072 [MiTarget™ MicroRNA 3′ UTR Clone]
- Yang, X.Y., et al. (2022). Circular RNA 0010117 promotes aggressive glioblastoma behavior by regulating the miRNA-6779-5p/SPEN axis. Transl Oncol doi: 10.1016/j.tranon.2022.101515 [miArrest™ miRNA Inhibitors; miTarget™ 3′ UTR miRNA Target Clones; Luc-Pair™ Duo-Luciferase Assay Kit 2.0]
- Zheng, T., et al. (2022). MiR-30c-5p loss-induced PELI1 accumulation regulates cell proliferation and migration via activating PI3K/AKT pathway in papillary thyroid carcinoma. Journal of Translational Medicine doi: 10.1186/s12967-021-03226-1 [miTarget™ PEL1 wild type and mutant 3′ UTR clones]
- Smith, A.J., et al. (2022). miR-520a-5p regulates Frizzled 9 expression and mediates effects of cigarette smoke and iloprost chemoprevention. Scientific Reports doi: 10.1038/s41598-022-06292-7 [miTarget™ FZD9 3′ UTR clone]
- Haugen, O.P., et al. (2022). Transcriptomic and functional studies reveal miR-431-5p as a tumour suppressor in pancreatic ductal adenocarcinoma cells. Gene doi: 10.1016/j.gene.2022.146346 [miTarget™ HCAR1, ATP6V0E1 3′ UTR clones]
- Wang, R. and Lahiri, D.K. (2022). Effects of microRNA-298 on APP and BACE1 translation differ according to cell type and 3′-UTR variation. Scientific Reports doi: 10.1038/s41598-022-05164-4 [miTarget™ APP 3′ UTR clone]
- Shemirani, R., et al. (2022). A miRNA derived from amelogenin exon4 regulates expression of transcription factor Runx2 by directly targeting upstream activators Nfia and Prkch. The Journal of Biological Chemistry doi: 10.1016/j.jbc.2022.101807 [miExpress™ miR-exon4 inhibitor clone]
- Chang, C., et al. (2022). The aberrant upregulation of exon 10-inclusive SREK1 through SRSF10 acts as an oncogenic driver in human hepatocellular carcinoma. Nature Communications doi: 10.1038/s41467-022-29016-x [miTarget™ 3′ UTR clones]
- Yang, B., et al. (2022). Evaluation of Early Biomarkers of Atherosclerosis Associated with Polychlorinated Biphenyl Exposure: An in Vitro and in Vivo Study. Environmental Health Perspectives doi: 10.1289/EHP9833 [miTarget™ GF-β2, PPME1 3′ UTR clones]
- Laitinen, P., et al. (2022). Nuclear microRNA-466c regulates Vegfa expression in response to hypoxia. PLOS ONE doi: 10.1371/journal.pone.0265948 [miTarget™ Vegfa 3′ UTR clone]
- Desrochers, G.F., et al. (2022). microRNA-27b regulates hepatic lipase enzyme LIPC and reduces triglyceride degradation during hepatitis C virus infection. Journal of Biological Chemistry doi: 10.1016/j.jbc.2022.101983 [miTarget™ LIPC 3′ UTR clone]
- Hecker, M., et al. (2022). Implication of genetic variants in primary microRNA processing sites in the risk of multiple sclerosis. eBiomedicine doi: 10.1016/j.ebiom.2022.104052 [miTarget™ 3′ UTR clone]
- Kim, S.M., et al. (2022). Hyaluronan synthase 2, a target of miR-200c, promotes carbon tetrachloride-induced acute and chronic liver inflammation via regulation of CCL3 and CCL4. Experimental and Molecular Medicine doi: 10.1038/s12276-022-00781-5 [miTarget™ HAS2 3′ UTR clone]
- Son, E.S., e al. (2022). miRNA-6515-5p regulates particulate matter-induced inflammatory responses by targeting CSF3 in human bronchial epithelial cells. Toxicology in vitro doi: 10.1016/j.tiv.2022.105428 [miTarget™ CSF3 3′ UTR clone]
- Zhang, T., et al. (2022). Epstein–Barr virus-encoded microRNA BART22 serves as novel biomarkers and drives malignant transformation of nasopharyngeal carcinoma. Cell Death & Disease doi: 10.1038/s41419-022-05107-x [miTarget™ MOSPD2 3′ UTR clone]
- Grieco, G.E., et al. (2022). Reduced miR-184-3p expression protects pancreatic β-cells from lipotoxic and proinflammatory apoptosis in type 2 diabetes via CRTC1 upregulation. Cell Death Discovery doi: 10.1038/s41420-022-01142-x [miTarget™ CRTC1 3′ UTR clone]
2021
- Ying, W., et al. (2021). MiR-690, an exosomal-derived miRNA from M2-polarized macrophages, improves insulin sensitivity in obese mice. Cell Metabolism doi: 10.1016/j.cmet.2020.12.019 [miTarget™ Nadk 3′ UTR clone]
- Iwasaki, H., et al. (2021). MicroRNA-494-3p inhibits formation of fast oxidative muscle fibres by targeting E1A-binding protein p300 in human-induced pluripotent stem cells. Scientific Reports doi: 10.1038/s41598-020-80742-y [miTarget™ p300 3′ UTR clone]
- Zhang, W-B., et al. (2021). Activation of Nrf2 by miR-152 Inhibits Doxorubicin-InducedCardiotoxicity via Attenuation of Oxidative Stress, Inflammation,and Apoptosis. Oxidative Medicine and Cellular Longevity doi: 10.1155/2021/8860883 [miTarget™ Keap1 3′ UTR clone]
- Mikami, Y., et al. (2021). MicroRNA-221 and -222 modulate intestinal inflammatory Th17 cell response as negative feedback regulators downstream of interleukin-23. Immunity doi: 10.1016/j.immuni.2021.02.015 [miTarget™ Maf, Il23r 3′ UTR clones]
- Purvis, N., et al. (2021). Diabetes induces dysregulation of microRNAs associated with survival, proliferation and self-renewal in cardiac progenitor cells. Diabetologia doi: 10.1007/s00125-021-05405-7 [miTarget™ Vdac1 3′ UTR clone]
- Li, J., et al. (2021). Biliverdin Protects Against Cerebral Ischemia/ Reperfusion Injury by Regulating the miR-27a-3p/ Rgs1 Axis. Neuropsychiatric Disease and Treatment 2021:17 1165–1181 [miTarget™ Rgs1 3′ UTR clone]
- Yeh, M., et al. (2021). MicroRNA-138 suppresses glioblastoma proliferation through downregulation of CD44. Scientific Reports doi: 10.1038/s41598-021-88615-8 [miTarget™ CD44 3′ UTR clone]
- Ibrahim, S., et al. (2021). β-Cell pre-miR-21 Induces Dysfunction and Loss of Cellular Identity by TargetingTransforming Growth Factor Beta 2 (Tgfb2) and Smad Family Member 2 (Smad2)mRNAs. [miTarget™ Tgfb2, Smad2 wild type and mutant 3′ UTR clones]
- Chen, P., et al. (2021). N6-methyladenosine demethylase ALKBH5 suppresses malignancy of esophageal cancer by regulating microRNA biogenesis and RAI1 expression. Oncogene doi: 10.1038/s41388-021-01966-4 [miTarget™ RAI1 3′ UTR clone]
- Kim, D.A., et al. (2021). Exosomal miR-1260b derived from non-small cell lung cancer promotes tumor metastasis through the inhibition of HIPK2. Cell Death & Disease doi: 10.1038/s41419-021-04024-9 [miTarget™ HIPK2 3′ UTR clone]
- Ofir-Birin, Y., et al. (2021). Malaria parasites both repress host CXCL10 and use it as a cue for growth acceleration. Nature Communications doi: 10.1038/s41467-021-24997-7 [miTarget™ CXCL10 3′ UTR clone]
- Deng, L., et al. (2021). Bioengineered miR-124-3p prodrug selectively alters the proteome of human carcinoma cells to control multiple cellular components and lung metastasis in vivo. Acta Pharmaceutica Sinica B doi: 10.1016/j.apsb.2021.07.027 [miTarget™ PLEC 3′ UTR clone]
- Smolka, C., et al. (2021). MiR-100 overexpression attenuates high fat diet induced weight gain, liver steatosis, hypertriglyceridemia and development of metabolic syndrome in mice. Molecular Medicine doi: 10.1186/s10020-021-00364-6 [miTarget™ CD36 3′ UTR clone]
- Beveridge, D.J., et al. (2021). The tumor suppressor miR-642a-5p targets Wilms Tumor 1 gene and cell-cycle progression in prostate cancer. Scienctific Reports doi: 10.1038/s41598-021-97190-x [miTarget™ WT1 3′ UTR clone]
- Sharma, N., et al. (2021). Herpes simplex virus 1 evades cellular antiviral response by inducing microRNA-24, which attenuates STING synthesis. PLOS Pathogens doi: 10.1371/journal.ppat.1009950 [miTarget™ STING 3′ UTR clone]
- Weissman, R., et al. (2021). MicroRNA-15a-5p acts as a tumor suppressor in histiocytosis by mediating CXCL10-ERK-LIN28a-let-7 axis. Leukemia doi: 10.1038/s41375-021-01472-2 [miTarget™ CXCL10 3′ UTR clone]
- Omura, T., et al. (2021). MicroRNA-101 Regulates 6-Hydroxydopamine-Induced Cell Death by Targeting Suppressor/Enhancer Lin-12-Like in SH-SY5Y Cells. Frontiers in Molecular Neuroscience doi: 10.3389/fnmol.2021.748026 [miTarget™ SEL1L 3′ UTR clone]
2020
- Hackett, E.L., et al. (2020). Mycobacterium tuberculosis Limits Host Glycolysis and IL-1β by Restriction of PFK-M via MicroRNA-21. Cell Reports doi: 10.1016/j.celrep.2019.12.015 [miTarget™ wild type and mutant hPFK 3′ UTR clones]
- Tai, F., et al. (2020). Enhanced JunD/RSK3 signalling due to loss of BRD4/FOXD3/miR-548d-3p axis determines BET inhibition resistance. Nature Communications doi: 10.1038/s41467-019-14083-4 [miTarget™ wild type and mutant JUND 3′ UTR clones]
- Kim, J.Y., et al. (2020). Induction of E6AP by microRNA-302c dysregulation inhibits TGF-β-dependent fibrogenesis in hepatic stellate cells. Scientific Reports doi: 10.1038/s41598-019-57322-w [miTarget™ E6AP 3′ UTR clones]
- Okamura, T., et al. (2020). miR-23b-3p acts as a counter-response against skeletal muscle atrophy. Journal of Endocrinology doi: 10.1530/JOE-19-0425 [miTarget™ PTEN 3′ UTR clones]
- Nakamura, M., et al. (2020). MicroRNA‑22 enhances radiosensitivity in cervical cancer cell lines via direct inhibition of c‑Myc binding protein, and the subsequent reduction in hTERT expression. Oncology Letters doi: 10.3892/ol.2020.11344 [miTarget™ MYCBP 3′ UTR clone]
- KIm, J.Y., et al. (2020). Induction of E6AP by microRNA-302c dysregulation inhibits TGF-β-dependent fibrogenesis in hepatic stellate cells. Scientific Reports doi: 10.1038/s41598-019-57322-w [miTarget™ E6AP 3′ UTR clone]
- Sindi, H.A., et al. (2020). Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension. Nature Communications doi: 10.1038/s41467-020-14966-x [miTarget™ Notch-4, ETS-1 3′ UTR clones]
- Luo, Y., et al. (2020).MicroRNA-503-3p affects osteogenic differentiation of human adipose-derived stem cells by regulation of Wnt2 and Wnt7b under cyclic strain. Stem Cell Research & Therapy doi: 10.1186/s13287-020-01842-0 [miTarget™ Wnt2, Wnt7b wt andf mutant 3′ UTR clones]
- Du, P., et al. (2020). Chronic stress promotes EMT-mediated metastasis through activation of STAT3 signaling pathway by miR-337-3p in breast cancer. Cell Death & Disease doi: 10.1038/s41419-020-02981-1 [miTarget™ Wnt2, Stat3 wt and mutant 3′ UTR clones]
- Wu, F., et al. (2020). miR-19b targets pulmonary endothelial syndecan-1 following hemorrhagic shock. Scientific Reports doi: 10.1038/s41598-020-73021-3 [miTarget™ Sdc1 wt and mutant 3′ UTR clones]
- Zhang, Q., et al. (2020). LncRNA HOTAIR Promotes Neuronal Damage Through Facilitating NLRP3 Mediated-Pyroptosis Activation in Parkinson’s Disease via Regulation of miR-326/ELAVL1 Axis. Cellular and Molecular Neurology doi: 10.1007/s10571-020-00946-8 [miTarget™ HOTAIR, ELAVL1 3′ UTR clones]
- Wang, L., et al. (2020). A MicroRNA Linking Human Positive Selection and Metabolic Disorders. Cell doi: 10.1016/j.cell.2020.09.017 [miTarget™ PPARg, PPARa, PGC1a, PRDM16 3′ UTR clones]
- Gillespie, O.M., et al. (2020). TMEM63C, a Potential Novel Target for Albuminuria Development, Is Regulated by MicroRNA-564 and Transforming Growth Factor beta in Human Renal Cells. Kidney and Blood Pressure Research doi: 10.1159/000508477 [miTarget™ TMEM63C 3′ UTR clone]
- Lee, D-H., et al. (2020). Mir214-3p and Hnf4a/Hnf4α reciprocally regulate Ulk1 expression and autophagy in nonalcoholic hepatic steatosis. Autophagy doi: 10.1080/15548627.2020.1827779 [miTarget™ Ulk1, Hnf4a 3′ UTR clones]
- Hamid, S., et al. (2020). Inositol-requiring enzyme-1 regulates phosphoinositide signaling lipids and macrophage growth. EMBO Reports doi: 10.15252/embr.202051462 [miTarget™ Inppl1 3′ UTR clone]
- Coku, A., et al. (2020). The miR-183/96/182 Cluster Regulates the Functions of Corneal Resident Macrophages. Immunohorizons doi: 10.4049/immunohorizons.2000091 [miTarget™ mouse Runx1, mouse Maf 3′ UTR clones]
- Nouws, J., et al. (2020). MicroRNA miR-24-3p reduces DNA damage responses, apoptosis, and susceptibility to chronic obstructive pulmonary disease. JCI Insight doi: 10.1172/jci.insight.134218. [miTarget™ mouse Runx1, BIM 3′ UTR clone]
2019
- Jiang, Q., et al. (2019). Hyper-Editing of Cell-Cycle Regulatory and Tumor Suppressor RNA Promotes Malignant Progenitor Propagation. Cancer Cell doi: 10.1016/j.ccell.2018.11.017 [miTarget™ MDM2 3′ UTR clone]
- Wu, Y.Z, et al. (2019). Dysregulation of miR-431 and target gene FOXA1 in intestinal tissues of infants with necrotizing enterocolitis. The FASEB Journal doi: 10.1096/fj.201801470R [miTarget™ FOXA1 3′ UTR clone]
- He, Q., et al. (2019). MiR-206 reduced the malignancy of hepatocellular carcinoma cells in vitro by inhibiting MET and CTNNB1 gene expressions. RSC Advances doi: 10.1039/C8RA09229J [miTarget™ MRT, CTNNB1 3′ UTR clones]
- Jiang, M., et al. (2019). p16INK4a Inhibits the Proliferation of Osteosarcoma Cells Through Regulating the miR- 146b -5p/TRAF6 Pathway. Bioscience Reports doi: 10.1042/BSR20181268 [miTarget™ TRAF6 wild type and mutant 3′ UTR clones]
- Hayashi, M., et al. (2019). Autoregulation of Osteocyte Sema3A Orchestrates Estrogen Action and Counteracts Bone Aging. Cell Metabolism doi: 10.1016/j.cmet.2018.12.021 [miTarget™ 3′ UTR clone]
- Romero-Ruiz, A., et al. (2019). Deregulation of miR-324/Kiss1/kisspeptin in early ectopic pregnancy: Mechanistic findings with clinical and diagnostic implications. American Journal of Obstetrics and Gynecology. 10.1016/j.ajog.2019.01.228 [miTarget™ KISS1 3′ UTR clone]
- Schwarzenbacher, D., et al. (2019). MiR-1287-5p inhibits triple negative breast cancer growth by interaction with phosphoinositide 3-kinase CB, thereby sensitizing cells for PI3Kinase inhibitors. Breast Cancer Research doi: 10.1186/s13058-019-1104-5 [miTarget™ PIC3CB 3′ UTR clone]
- Hackett, E. (2019). MicroRNA-21 Limits Macrophage Responses to Mycobacterium tuberculosis. Ph.D. Thesis, University of Dublin [miTarget™ PFK-M 3′ UTR clone]
- Hecker, M., et al. (2019). A genetic variant associated with multiple sclerosis inversely affects the expression of CD58 and microRNA-548ac from the same gene. PLOS Genetics doi: 10.1371/journal.pgen.1007961 [miTarget™ SDC-4 3′ UTR clone]
- Park, M.K., et al. (2019). PTEN self-regulates through USP11 via the PI3K-FOXO pathway to stabilize tumor suppression. Nature communications doi: 10.1038/s41467-019-08481-x [miTarget™ USP11 3′ UTR clone]
- Yuan, D., et al. (2019). Regulatory effect of host miR-101b-3p on parasitism of nematode Angiostrongylus cantonensis via superoxide dismutase 3. Biochimica et Biophysica Acta (BBA) – Gene Regulatory Mechanisms doi: 10.1016/j.bbagrm.2019.02.004 [miTarget™ 3′ UTR clone]
- Bishopric, N., et al. (2019). Compositions, kits and methods for treatment of cardiovascular,immunological and inflammatory diseases. United States Patent Application 15/012,052 [miTarget™ p300 3′ UTR clone]
- Liu, X., et al. (2019). miR-145-5p suppresses osteogenic differentiation of adipose-derived stem cells by targeting semaphorin 3A. In Vitro Cellular & Developmental Biology – Animal doi: 10.1007/s11626-019-00318-7 [miTarget™ Sema 3A 3′ UTR clone]
- Bishopric, N., et al. (2019). COMPOSITIONS , KITS AND METHODS FOR TREATMENT OF CARDIOVASCULAR , IMMUNOLOGICAL AND INFLAMMATORY DISEASES. United States Patent Application 10/201,557 [miTarget™ p300 3′ UTR clone]
- Tan, Y., et al. (2019). MiR-34b-3p Represses the Multidrug-Chemoresistance of Bladder Cancer Cells by Regulating the CCND2 and P2RY1 Genes. Medica Science Monitor doi: 10.12659/MSM.913746 [miTarget™ CCND2, P2RY1 3′ UTR clones]
- Amodio, N., et al. (2019). Replacement of miR-155 Elicits Tumor Suppressive Activity and Antagonizes Bortezomib Resistance in Multiple Myeloma. Cancers doi: 10.3390/cancers11020236 [miTarget™ PSMβ5 3′ UTR clone]
- Zheng, Y-L., et al. (2019). LINC01554-Mediated Glucose Metabolism Reprogramming Suppresses Tumorigenicity in Hepatocellular Carcinoma via Downregulating PKM2 Expression and Inhibiting Akt/mTOR Signaling Pathway. Theranostics doi: 10.7150/thno.28992 [miTarget™ LINC01554 3′ UTR clone]
- Wang, Z., et al. (2019). Inhibition of miRNA-27b enhancesneurogenesisvia AMPK activationina mouseischemic stroke model. OpenBio doi: 10.1002/2211 – 5463. 12614 [miTarget™ wild type and mutant AMPKα2 3′ UTR clones]
- Ramanathan, S. , et al. (2019). Exosome microRNA signatures in patients with complex regional pain syndrome undergoing plasma exchange. Journal of Translational Medicine doi: 10.1186/s12967-019-1833-3 [miTarget™ IL6 3′ UTR clone]
- Gu, Y., et al. (2019). miR-370 inhibits the angiogenic activity of endothelial cells by targeting smoothened (SMO) and bone morphogenetic protein (BMP)-2. The FASEB Journal doi: 10.1096/fj.201802085RR [miTarget™ SMO 3′ UTR clone]
- Bhagirath, D., et al. (2019). Role of a novel race-related tumor suppressor microRNA located in frequently deleted chromosomal locus 8p21 in prostate cancer progression. Carcinogenesis doi: 10.1093/carcin/bgz058 [miTarget™ SLUG 3′ UTR clone]
- Yang, S., et al. (2019). miRNA‑214 suppresses oxidative stress in diabetic nephropathy via the ROS/Akt/mTOR signaling pathway and uncoupling protein 2. Experimental and Therapeutic Medicine doi: 10.3892/etm.2019.7359 [miTarget™ UCP2 3′ UTR clone]
- Chen, Y., et al. (2019). Let‑7a inhibits proliferation and promotes apoptosis of human asthmatic airway smooth muscle cells. Experimental and Therapeutic Medicine doi: 10.3892/etm.2019.7363 [miTarget™ STAT3 3′ UTR clone]
- Zhang, B., et al. (2019). Long non-coding RNA LOXL1-AS1 acts as a ceRNA for miR-324-3p to contribute to cholangiocarcinoma progression via modulation of ATP-binding cassette transporter A1. Biochemical and Biophysical Research Communications doi: 10.1016/j.bbrc.2019.04.089 [miTarget™ LOXL1-AS1 or ABCA1 3′ UTR clones]
- Guo, J., et al. (2019) A novel circular RNA circ-ZNF652 promotes hepatocellular carcinoma metastasis through inducing snail-mediated epithelial-mesenchymal transition by sponging miR-203/miR-502-5p. Biochemical and Biophysical Research Communications doi: 10.1016/j.bbrc.2019.03.214 [miTarget™ circ-ZNF652/ Snail 3′ UTR clone]
- Zhang, W.C., et al. (2019). miR-147b-mediated TCA cycle dysfunction and pseudohypoxia initiate drug tolerance to EGFR inhibitors in lung adenocarcinoma. Nature Metabolism doi: 10.1038/s42255-019-0052-9 [miTarget™ VHL or SDHD 3′ UTR clones]
- dosSantos, D.D.B. (2019). Discovery of oncofetal microRNA-gene networks associated with lung cancer aggressiveness. Ph.D. Thesis, University of British Columbia [miTarget™ NFIB 3′ UTR clone]
- Wang, C-Y., et al. (2019). Elevated miR‐200a and miR‐141 inhibit endocrine gland‐derived vascular endothelial growth factor expression and ciliogenesis in preeclampsia. The Journal of Physiology doi: 10.1113/JP277704 [miTarget™ NFIB 3′ UTR clone]
- Li, C., et al. (2019). LncRNA AWPPH promotes osteosarcoma progression via activation of Wnt/β-catenin pathway through modulating miR-93-3p/FZD7 axis. Biochemical and Biophysical Research Communications doi: 10.1016/j.bbrc.2019.04.203 [miTarget™ wild type and mutant FOX1 3′ UTR clones]
- Chu, J.Y.S., et al. (2019). miR-200c Prevents TGF-b1-Induced Epithelial-to-Mesenchymal Transition and Fibrogenesis inMesothelial Cells by Targeting ZEB2 and Notch1. Molecular Therapy Nucleic Acids doi: https://doi.org/10.1016/j.omtn.2019.05.008 [miTarget™ ZEB2, Notch1, Jagged2 3′ UTR clones]
- von Gamm, M., et al. (2019). Immune homeostasis and regulation of theinterferon pathway require myeloid-derivedRegnase-3. Journal of Experimental Medicine doi: 10.1084/jem.20181762 [miTarget™ HPRT, Ifng, Zc3h12a3′ UTR clones]
- Cheng, W-L., et al. (2019). MicroRNA‐133 suppresses ZFHX3‐dependent atrial remodelling and arrhythmia. Acta physiologica doi: 10.1111/apha.13322 [miTarget™ FGFR1 3′ UTR clone]
- Mazzone, A., et al. (2019), microRNA overexpression in slow transit constipation leads to reduced NaV1.5 current and altered smooth muscle contractility. Gut doi: 10.1136/gutjnl-2019-318747 [miTarget™ SCN5A 3′ UTR clone]
- Wei, J., et al. (2019). Targeting REGNASE-1 programs long-lived effector T cells for cancer therapy. Nature doi: 10.1038/s41586-019-1821-z [miTarget™ Baf, Il2, and Il4 3′ UTR clones]
- Chen, G., et al. (2019). MiR-148a agomir based targeting of c-Met and Her-3 is able to attenuate EGFR-T790M mutation driven gefitinib and erlotinib resistance in non-small cell lung cancer cells. RSC Advances doi: 10.1039/C8RA10224D [miTarget™ UBE2D2 3′ UTR clone] rcp252148
- Bartoszewska, S., et al. (2019). miR-34c-5p modulates X-box–binding protein 1 (XBP1) expression during the adaptive phase of the unfolded protein response. The FASEB Journal doi: 10.1096/fj.201900600RR [miTarget™ XPB1s, XPB1u 3′ UTR clones]
- Allepuz, RDA, et al. (2019). Modulation of micrornas against myotonic dystrophy type 1 and antagonists of micrornas therefor. United States Patent Application 16/334,725 [miTarget™ MBNL1, MBNL2 3′ UTR clones]
2018
- Kikulska, A., et al. (2018). Coordinated expression and genetic polymorphisms in Grainyhead-like genes in human non-melanoma skin cancers. BMC Cancer doi: 10.1186/s12885-017-3943-8 [miTarget™ wild type and mutant GRHL1 3′ UTR clones]
- Lai, X., et al. (2018). MiR -205- 5p and miR- 342- 3p cooperate in the repression of the E2F1 transcription factor in the context of anticancer chemotherapy resistance. Theranostics doi: 10.7150/ thno .19904 [miTarget™ E2F1 3′ UTR clone]
- Xiong, K., et al. (2017). MicroRNA‑9 functions as a tumor suppressor and enhances radio‑sensitivity in radio‑resistant A549 cells by targeting neuropilin 1. Oncology Letters doi: 10.3892/ol.2017.7705 [miTarget™ 3′ UTR clone]
- Jiang, Y., et al. (2018). miRNA15a regulates insulin signal transduction in the retinal vasculature. Cellular Signaling doi: 10.1016/j.cellsig.2018.01.016 [miTarget™ insulin receptor 3′ UTR clone]
- Singaravelu, R., et al. (2018). MicroRNA-7 mediates cross-talk between metabolic signaling pathways in the liver. Scientific Reports doi: 10.1038/s41598-017-18529-x [miTarget™ NR1H2 3′ UTR clone]
- Frith, J.E., et al. (2018). Mechanically-sensitive miRNAs bias human mesenchymal stem cell fate via mTOR signalling. Nature Communications doi: 10.1038/s41467-017-02486-0 [miTarget™ mTOR 3′ UTR clone]
- Sun, J., et al. (2018).MiR-19 regulates the proliferation and invasion of glioma by RUNX3 via β-catenin/Tcf-4 signaling. Oncotarget doi: 10.18632/oncotarget.22720 [miTarget™ RUNX3 3′ UTR clone]
- Tinaburri, L., et al. (2018). Mir-200a modulates the expression of the dna repair protein ogg1 playing a role in aging of primary human keratinocytes. Oxidative Medicine and Cellular Longevity Jauary 22, 2018 [miTarget™ OGG1 3′ UTR clone]
- Dang, Y., et al. (2018). MicroRNA-379-5p is associate with biochemical premature ovarian insufficiency through PARP1 and XRCC6. Cell Death & Disease doi: 10.1038/s41419-017-0163-8 [miTarget™ PARP1 and XRCC6 3′ UTR clones]
- Kishire, R., et al. (2018). Use of MicroRNA 375 in Augmenting Stem Cell Based and Endogenous Ischemic Tissue Repair. United States Patent Application 20180008641 [miTarget™ PDK-1 3′ UTR clone]
- Mohammadi, A., et al. (2018). Differential expression of microRNAs in peripheral blood mononuclear cells identifies autophagy and TGF-beta related signatures aberrantly expressed in inflammatory bowel disease. Journal of Chrohn’s and Colitis doi: 10.1093/ecco-jcc/jjy010 [miTarget™ ATG16L1 3′ UTR clone]
- Zhang, Z., et al. (2018). CRISPR/CAS9 ablation of individual miRNAs from a miRNA family reveals their individual efficacies for regulating cardiac differentiation. Mechanisms of Development doi: 10.1016/j.mod.2018.02.002 [miTarget™ FOG2 3′ UTR clone]
- Nigro, C., et al. (2018). miR-214-Dependent Increase of PHLPP2 Levels Mediates the Impairment of Insulin-Stimulated Akt Activation in Mouse Aortic Endothelial Cells Exposed to Methylglyoxal. International Journal of Molecular Sciences doi: 10.3390/ijms19020522 [miTarget™ PHLPP2 3′ UTR clone]
- Mellado-Gil, J.M., et al. (2018). The type 2 diabetes-associated HMG20A gene is mandatory for islet beta cell functional maturity. Cell Death & Disease doi: 10.1038/s41419-018-0272-z [miTarget™ wild type and mutant DMT2 3′ UTR clone]
- Srivistava, A., et al. (2018). Chronic hyperinsulinemia induced miR-27b is linked to adipocyte insulin resistance by targeting insulin receptor. Journal of Molecular Medicine doi: 10.1007/s00109-018-1623-z [miTarget™ INSR 3′ UTR clone]
- Witkowski, M., et al. (2018). MicroRNA-19a contributes to the epigenetic regulation of tissue factor in diabetes. Cardiovascular Diabetology doi: 10.1186/s12933-018-0678-z [miTarget™ F3 3′ UTR clone]
- Chinnappan, M., et. al. (2018). Network of MicroRNAs Mediate Translational Repression of Bone Morphogenetic Protein Receptor‐2: Involvement in HIV‐Associated Pulmonary Vascular Remodeling. Journal of the American Heart Association doi: 10.1161/JAHA.117.008472 [miTarget™ BMPR2 3′ UTR clone]
- Zhu, E., et al. (2018). Cocaine Exposure Increases Blood Pressure and Aortic Stiffness via the miR-30c-5p–Malic Enzyme 1–Reactive Oxygen Species Pathway. Hypertension doi: /10.1161/HYPERTENSIONAHA.117.10213 [miTarget™ wild type and mutant Me1 3′ UTR clones]
- Kotlarek, M., et al. (2018). The rs2910164 Genetic Variant of miR-146a-3p Is Associated with Increased Overall Mortality in Patients with Follicular Variant Papillary Thyroid Carcinoma. International Journal of Molecular Sciences doi: 10.3390/ijms19030655 [miTarget™ hNIS 3′ UTR clone]
- Sinha, M., et al. (2018). Direct conversion of injury-site myeloid cells to fibroblast-like cells of granulation tissue. Nature Communications doi: 10.1038/s41467-018-03208-w [miTarget™ KLF5 3′ UTR clone]
- Yu, R., et al. (2018). miR‑377 targets CUL4A and regulates metastatic capability in ovarian cancer. International Journal of Molecular Medicine doi: 10.3892/ijmm.2018.3540 [miTarget™ wild type and mutant CUL4A 3′ UTR clones]
- Zhang, D., et al. (2018). MiR-30b-5p modulates glioma cell proliferation by direct targeting MTDH. Saudi Journal of Biological Sciences doi: 10.1016/j.sjbs.2018.02.015 [miTarget™ MTDH 3′ UTR clone]
- Cai, M., et al. (2018). Preeclampsia. United States Patent Application US20180050060A1 [miTarget™ sFlt-1 3′ UTR clone]
- Li, L., and Ma, L. (2018). Upregulation of miR-582-5p regulates cell proliferation and apoptosis by targeting AKT3 in human endometrial carcinoma. Saudi Journal of Biological Sciences doi: 10.1016/j.sjbs.2018.03.007 [miTarget™ AKT3 3′ UTR clone]
- Latonen, L., et al. (2018). Integrative proteomics in prostate cancer uncovers robustness against genomic and transcriptomic aberrations during disease progression. Nature Communications doi: 10.1038/s41467-018-03573-6 [miTarget™ MDH2 3′-UTR clone]
- Si, S., et al. (2018). Effect of miR-146a-5p on proliferation and metastasis of triple-negative breast cancer via regulation of SOX5. Experimental and Tehrapeutic Medicine doi: 10.3892/etm.2018.5945 [miTarget™ SOX5 3′-UTR clone]
- Li, X., et al. (2018). miR-148b-3p inhibits gastric cancer metastasis by inhibiting the Dock6/Rac1/Cdc42 axis. Journal of Experimental & Clinical Cancer Research doi: 10.1186/s13046-018-0729-z [miTarget™ Dock6 3′-UTR clone]
- Ramalho-Carvalho, J, et al. (2018). A multiplatform approach identifies miR-152-3p as a common epigenetically regulated onco-suppressor in prostate cancer targeting TMEM97. Clinical Epigenetics doi: 10.1186/s13148-018-0475-2 [miTarget™ NOL4 3′-UTR clone]
- Cao, C., et al. (2018). Cyclic Biaxial Tensile Strain Promotes Bone Marrow-Derived Mesenchymal Stem Cells to Differentiate into Cardiomyocyte-like Cells by miRNA-27a. The International Journal of Biochemistry & Cell Biology doi: 10.1016/j.biocel.2018.04.004 [miTarget™ SCF 3′-UTR clone]
- Jia, L., et al. (2018). MiR-34a Regulates Axonal Growth of Dorsal Root Ganglia Neurons by Targeting FOXP2 and VAT1 in Postnatal and Adult Mouse. Molecular Neurobiology doi: 10.1007/s12035-018-1047-3 [miTarget™ FOXP2, VAT1 3′-UTR clones]
- Zhang, B., et al. (2018). TSPAN15 interacts with BTRC to promote oesophageal squamous cell carcinoma metastasis via activating NF-κB signaling. Nature Communications doi: 10.1038/s41467-018-03716-9 [miTarget™ TSPAN15 3′-UTR clone]
- Gu, W., et al. (2018). Smooth muscle cells differentiated from human mesenchymal stem cells regulated by microRNA (miR)-503 and miR-222-5p are suitable for vascular tissue engineering. The Journal of Biological Chemistry doi: 10.1074/jbc.RA118.001739 [miTarget™ 3′-UTR clone]
- Hu, K., et al. (2018). Metadherin is an apoptotic modulator in prostate cancer through miR-342-3p regulation. Saudi Journal of Biological Sciences doi: 10.1016/j.sjbs.2018.04.015 [miTarget™ MTDH 3′-UTR clone]
- Shi, J., et al. (2018). miR‑486‑5p is upregulated in osteoarthritis and inhibits chondrocyte proliferation and migration by suppressing SMAD2. Molecular Medicine Reports doi: 10.3892/mmr.2018.8931 [miTarget™ wild-type and mutant SMAD2 3′-UTR clones]
- Li, W., et al. (2018). microRNA‑124‑3p inhibits the progression of congenital hypothyroidism via targeting programmed cell death protein 6. Experimental and Therapeutic Medicine doi: 10.3892/etm.2018.6062 [miTarget™ wild-type and mutant PDCD6 3′-UTR clones]
- Puertas, R.D., et al. (2018). Analysis of the microRNA signature in left atrium from patients with valvular heart disease reveals their implications in atrial fibrillation. PLOS ONE doi: 10.1371/journal.pone.0196666 [miTarget™ Smyd2 3′ UTR clone]
- Verdelli, C., et al. (2018). The aberrantly expressed miR-372 partly impairs sensitivity to apoptosis in parathyroid tumor cells. Endocrine-Related Cancer doi: 10.1530/ERC-17-0204 [miTarget™ p21 218, LATS2 3′ UTR clones]
- Higaki, S., et al. (2018). Defensive effect of microRNA-200b/c against amyloid-beta peptide-induced toxicity in Alzheimer’s disease models. PLOS ONE doi: 10.1371/journal.pone.0196929 [miTarget™ S6K1, JUN, SRSF1, SRSF1-a, SRSF1-b 3′ UTR clones]
- Lin, C-H., et al. (2018). MicroRNA-328 inhibits migration and epithelial–mesenchymal transition by targeting CD44 in nasopharyngeal carcinoma cells. OncoTargets and Therapy doi: 10.2147/OTT.S151665 [miTarget™ CD44 3′ UTR clone]
- Fa, Z., et al. (2018). MicroRNA‑150 suppresses the growth and malignant behavior of papillary thyroid carcinoma cells via downregulation of MUC4. Experimental and Therapeutic Medicine doi: 10.3892/etm.2018.6197 [miTarget™ MUC4 3′ UTR clone]
- Labouesse, M.A., et al. (2018). MicroRNA Expression Profiling in the Prefrontal Cortex: Putative Mechanisms for the Cognitive Effects of Adolescent High Fat Feeding. Scientific Reports doi: 10.1038/s41598-018-26631-x [miTarget™ EFNA3 3′ UTR clone]
- Karthikeyan, A., et al. (2018). Microglial SMAD4 regulated by microRNA-146a promotes migration of microglia which support tumor progression in a glioma environment. Oncotarget doi: 10.18632/oncotarget.25116 [miTarget™ SMAD4 3′ UTR clone]
- Aikawa, E., et al. (2018). SORTILIN 1 IS A NOVEL INDUCER OF VASCULAR CALCIFICATION. United States Patent Application 20180163211 [miTarget™ SORT1 3′ UTR clone]
- Cerro-Herreros, E., et al. (2018). miR-23b and miR-218 silencing increase Muscleblind-like expression and alleviate myotonic dystrophy phenotypes in mammalian models. Nature Communications doi: 10.1038/s41467-018-04892-4 [miTarget™ MBNL1 and MBNL2 3′ UTR clones]
- Li, L., et al. (2018). Comparison of multi-lineage differentiation of hiPSCs reveals novel miRNAs that regulate lineage specification. Scientific Reports doi: 10.1038/s41598-018-27719-0 [miTarget™ MGAT4C, PKD1, and PKD2 3′ UTR clones]
- Norcini, M., et al. (2018). Intrathecal Injection of miR-133b-3p or miR-143-3p Prevents the Development of Persistent Cold and Mechanical Allodynia Following a Peripheral Nerve Injury in Rats. Neuroscience doi: 10.1016/j.neuroscience.2018.06.040 [miTarget™ Scn2b, Piezo2 3′ UTR clones]
- Rajan, S. and Panzade, G. (2018). miR-876-3p regulates glucose homeostasis and insulin sensitivity by targeting adiponectin. Journal of Endocrinology doi: 10.1530/JOE-17-0387 [miTarget™ ADIPOQ 3′ UTR clone]
- Qiu, L., et al. (2018). miR-155 Modulates Cockroach Allergen– and Oxidative Stress–Induced Cyclooxygenase-2 in Asthma. Journal of Immunology doi: 10.4049/jimmunol.1701167 [miTarget™ COX-2 3′ UTR clone]
- Curtiss, E., et al. (2018). miR15a regulates NLRP3 inflammasome proteins in the retinal vasculature. Experimental Eye Research doi: 10.1016/j.exer.2018.07.005 [miTarget™ Foxo1 3′ UTR clone]
- Sullivan, T.B., et al. (2018). Spatiotemporal microRNA profile in peripheral nerve regeneration: miR-138 targets vimentin and inhibits Schwann cell migration and proliferation. Neural Regeneration Research doi: 10.4103/1673-5374.235073 [miTarget™ vimentin 3′ UTR clone]
- Wang, J., et al. (2018). Zeb1 Regulate s the Symmetric Division of Mouse Lewis Lung Carcinoma Stem Cells through Numb mediated by miR -31. International Journal of Biological Sciences doi: 10.7150/ ijbs .27446 [miTarget™ Zeb1 3′ UTR clone]
- Raab, A. (2018). The role of Rgs2 in animal models of affective disorders. Ph. D. Thesis, University of Würzburg [miTarget™ Rgs2 3′ UTR clone]
- Hui, W., et al. (2018). MicroRNA-1292-5p inhibits cell growth, migration and invasion of gastric carcinoma by targeting DEK. Am J Cancer Res 2018;8(7):1228-1238 [miTarget™ DEK 3′ UTR clone]
- Du, L., et al. (2018). MiR-206 is down-regulated and suppresses cell proliferation by targeting FOXP1 in brain gliomas. Int J Clin Exp Pathol 2018;11(7):3405-3415 [miTarget™ FOXP1 3′ UTR clone]
- Xiong, Y., et al. (2018). miR-190 promotes HCC proliferation and metastasis by targeting PHLPP1. Experimental Cell Research doi: 10.1016/j.yexcr.2018.08.008 [miTarget™ PHLPP1 3′ UTR clone]
- Leslie, P.L., et al. (2018). p53 Regulates the Expression of LRP1 and Apoptosis through a Stress Intensity-Dependent MicroRNA Feedback Loop. Cell Reports doi: 10.1016/j.celrep.2018.07.010 [miTarget™ LRP1 3′ UTR clone]
- Johnstone, A., et al. (2018). EZH1 is an antipsychotic-sensitive epigenetic modulator of social and motivational behavior that is dysregulated in schizophrenia. Neurobiology of Disease doi: 10.1016/j.nbd.2018.08.005 [miTarget™ EZH1 3′ UTR clone]
- Kim, K.C., et al. (2018). Suppression of metastasis through inhibition of chitinase 3-like 1 expression by miR -125a -3p-mediated up-regulation of USF1. Theranostics doi: 10.7150/ thno .26467 [miTarget™ USF1 3′ UTR clone]
- Liao, G., et al. (2018). MicroRNA miR-509 Regulates ERK1/2, the Vimentin Network, and Focal Adhesions by Targeting Plk1. Scentific Reports doi: 10.1038/s41598-018-30895-8 [miTarget™ Plk1 3′ UTR clone]
- Dong, Y., et al. (2018). MiR-876-5p modulates head and neck squamous cell carcinoma metastasis and invasion by targeting vimentin. Cancer Cell International doi: 10.1186/s12935-018-0619-7 [miTarget™ vimentin 3′ UTR clone]
- Kirchmeyer, M., et al. (2018). Cytokine-mediated modulation of the hepatic miRNome: miR-146b-5p is an IL-6-inducible miRNA with multiple targets. Journal of Leukocyte Biology doi: 0.1002/JLB.MA1217-499RR [miTarget™ 3′ UTR clone]
- Wang, Y., et al. (2018). Long non-coding RNA DSCR8 acts as a molecular sponge for miR-485-5p to activate Wnt/β-catenin signal pathway in hepatocellular carcinoma. Cell dEath & Disease doi: 10.1038/s41419-018-0937-7 [miTarget™ DSCR8, FZD7 3′ UTR clones]
- Li, Y., et al. (2018). Long non-coding RNA SNHG5 promotes human hepatocellular carcinoma progression by regulating miR-26a-5p/GSK3β signal pathway. Cell Death & Disease doi: 10.1038/s41419-018-0882-5 [miTarget™ SNHG5, GSK3β wild type and mutant 3′ UTR clones]
- Vashisht, A., et al. (2018). Regulation of proto-oncogene Orai3 by miR18a/b and miR34a. Cell Calcium doi: 10.1016/j.ceca.2018.08.006 [miTarget™ Orai3 3′ UTR clone]
- Zhang, C., et al. (2018). Hepatic Ago2-mediated RNA silencing controls energy metabolism linked to AMPK activation and obesity-associated pathophysiology. Nature Communications doi: 10.1038/s41467-018-05870-6 [miTarget™ Ampka1 3′ UTR clone]
- Zheng, F., et al. (2018). Inactivation of Stat3 and crosstalk of miRNA155-5p and FOXO3a contribute to the induction of IGFBP1 expression by beta-elemene in human lung cancer. Experimental and Molecular Medicine doi: 10.1038/s12276-018-0146-6 [miTarget™ FOXO3a 3′ UTR clone]
- Hourigan, S.T., et al., (2018). The regulation of miRNAs by reconstituted high-density lipoproteins in diabetes-impaired angiogenesis. Scientific Reports doi: 10.1038/s41598-018-32016-x [miTarget™ VEGFA 3′ UTR clone]
- Li, J., et al. (2018). microRNA-141-3p fosters the growth, invasion, and tumorigenesis of cervical cancer cells by targeting FOXA2. Archives of Biochemistry and Biophysics doi: 10.1016/j.abb.2018.09.008 [miTarget™ FOXA2 wild type and mutant 3′ UTR clones]
- Liu, J., et al. (2018). miR-361-5p inhibits glioma migration and invasion by targeting SND1. Oncotargets and Therapy doi: 10.2147/OTT.S171539 [miTarget™ SND1 3′ UTR clone]
- Ding, T., et al. (2018). Antisense Oligonucleotides against miR-21 Inhibit the Growth and Metastasis of Colorectal Carcinoma via the DUSP8 Pathway. Molecular Therapy Nucleic Acids doi: 10.1016/j.omtn.2018.09.004 [miTarget™ DUSP8 3′ UTR clone]
- Tang, L., et al. (2018). Downregulated miR‐187 contributes to the keratinocytes hyperproliferation in psoriasis. Journal of Cellular Physiology doi: 10.1002/jcp.27135 [miTarget™ CD276 3′ UTR clone]
- Li, C., et al. (2018). MicroRNA-552 promotes hepatocellular carcinoma progression by downregulating WIF1. International Journal of Molecular Medicine doi: 10.3892/ijmm.2018.3882 [miTarget™ WIF1 3′ UTR clone]
- Shen, P., et al. (2018). Metformin blocks MYC protein synthesis in colorectal cancer via mTOR-4EBP-eIF4E and MNK1-eIF4G-eIF4E signaling. Molecular Oncology doi:10.1002/1878-0261.12384 [miTarget™ MYC 3′ UTR clone]
- Torella, D., et al. (2018). MicroRNA Regulation of the Hyper-Proliferative Phenotype of Vascular Smooth Muscle Cells in Diabetes Mellitus. Diabetes doi: 10.2337/db17-1434 [miTarget™ EMP2 3′ UTR clone]
- Jin, Y., et al. (2018). MicroRNA-206 Downregulates Connexin43 in Cardiomyocytes to Induce Cardiac Arrhythmias in a Transgenic Mouse Model. Heart, Lung, and Circulation doi: 10.1016/j.hlc.2018.09.008 [miTarget™ Cx43 3′ UTR clone]
- Luo, W., et al. (2018). miR-135a-5p Functions as a Glioma Proliferation Suppressor by Targeting TRAF5 and Predicts Patients’ Prognosis. The American Journal of Pathology doi: 10.1016/j.ajpath.2018.08.019 [miTarget™ TRAF5 3′ UTR clone]
- Schaefer, A. and Greengard, P. (2018). COMPOSITIONS AND METHODS FOR MODULATING NEURONAL EXCITABILITY AND MOTOR BEHAVIOR. United States Patent Application 15/820,425 [miTarget™ RCS, TARPP 3′ UTR clones]
- Lozada-Delgado, E.L., et al. (2018). Targeting MicroRNA-143 Leads to Inhibition of
Glioblastoma Tumor Progression. Cancers doi: 10.3390/cancers10100382 [miTarget™ SLC30A8 3′ UTR clone] - Hommers, L.G., et al. (2018). A functional genetic variation of SLC6A2 repressor hsa-miR-579-3p upregulates sympathetic noradrenergic processes of fear and anxiety. Translational Psychiatry doi: 10.1038/s41398-018-0278-4 [miTarget™ SLC6A2 3′ UTR clone]
- Shi, S., et al. (2018). miR-29s function as tumor suppressors in gliomas by targeting TRAF4 and predict patient prognosis. Cell Death & Disease doi: 10.1038/s41419-018-1092-x [miTarget™ TRAF4 3′ UTR clone]
- Malcov-Borg, H., et al. (2018) UV-Protection Timer Controls Linkage between Stress and Pigmentation Skin Protection Systems. Molecular Cell doi: 10.1016/j.molcel.2018.09.022 [miTarget™ MITF 3′ UTR clone]
- Assama, H., et al. (2018). MicroRNA let-7d targets thrombospondin-1 and inhibits the activation of human pancreatic stellate cells. Pancreatology doi: 10.1016/j.pan.2018.10.0122 [miTarget™ 3′ UTR clone]
- Zhang, C., et al. (2018). The miR-199a-3p regulates the radioresistance of esophageal cancer cells via targeting the AK4 gene. Cancer Cell International doi: 10.1186/s12935-018-0689-6 [miTarget™ AK4 3′ UTR clone]
- Ding, X., et al. (2018). Ellagic acid ameliorates oxidative stress and insulin resistance in high glucose-treated HepG2 cells via miR-223/keap1-Nrf2 pathway. Biomedicine & Pharmacotherapy doi: 10.1016/j.biopha.2018.11.018 [miTarget™ KEAP1 wild type and mutant 3′ UTR clones]
- Zhu, J-F., et al. (2018). MicroRNA-133b/EGFR axis regulates esophageal squamous cell carcinoma metastases by suppressing anoikis resistance and anchorage-independent growth. Cancer Cell International doi: 10.1186/s12935-018-0684-y [miTarget™ EGFR 3′ UTR clone]
- Wang, J., et al. (2018). miR-339-5p Increases Radiosensitivity of Lung Cancer Cells by Targeting Phosphatases of Regenerating Liver-1 (PRL-1). Medical Science Monitor doi: 10.12659/MSM.910808 [miTarget™ PRL-1 wild type and mutant 3′ UTR clones]
- Mikuda, N., et al. (2018). The IκB kinase complex is a regulator of mRNA stability. The EMBO Journal doi: 10.15252/embj.201798658 [miTarget™ 3′ UTR clone]
- Malcov-Brog, H., et al. (2018). UV-Protection Timer Controls Linkage between Stress and Pigmentation Skin Protection Systems. Molecular Cell doi: 10.1016/j.molcel.2018.09.022 [miTarget™ MITF 3′ UTR clone]
- Kanlikilicer, P., et al. (2018). Exosomal miRNA confers chemo resistance via targeting Cav1/p-gp/M2-type macrophage axis in ovarian cancer. EBiomedicine doi: 10.1016/j.ebiom.2018.11.004 [miTarget™ Cav1 3′ UTR clone]
- Lu, J., et al. (2018). miR‑106a contributes to prostate carcinoma progression through PTEN. Oncology Letters doi: 10.3892/ol.2018.9697 [miTarget™ PTEN 3′ UTR clone]
- Liu, J., et al. (2018). miR‑200b and miR‑200c co‑contribute to the cisplatin sensitivity of ovarian cancer cells by targeting DNA methyltransferases. Oncology Letters doi: 10.3892/ol.2018.97454 [miTarget™ DNMT1/DNMT3A/DNMT3B wild type and mutant 3′ UTR clones]
- Cao, P., et al. (2018). MiR-15b is a key regulator of proliferation and apoptosis of chondrocytes from patients with condylar hyperplasia by targeting IGF1, IGF1R and BCL2. Osteoarthritis and Cartilage doi: 10.1016/j.joca.2018.09.010 [miTarget™ IGF1R, BCL-2 wild type and mutant 3′ UTR clones]
- Wang, S., et al. (2018). SUR2B/Kir6.1 channel openers correct endothelial dysfunction in chronic heart failure via the miR-1-3p/ET-1 pathway. Biomedicine & Pharmacotherapy doi: 10.1016/j.biopha.2018.11.135 [miTarget™ ET-1 wild type and mutant 3′ UTR clones]
- Hennessy, E.J., et al. (2018). The long noncoding RNA CHROME regulates cholesterol homeostasis in primates. Nature Metabolism doi: 10.1038/s42255-018-0004-9 [miTarget™ ABCA1, OSBPL8 3′ UTR clones]
- Reidel, L., et al. (2018). microRNA-29b mediates fibrotic induction of human xylosyltransferase-I in human dermal fibroblasts via the Sp1 pathway. Scientific Reports doi: 10.1038/s41598-018-36217-2 [miTarget™ XYLT1 3′ UTR clone]
- Kim, T., et al. (2018). The microRNA miR-7a-5p ameliorates ischemic brain damage by repressing α-synuclein. Science Signaling doi: 10.1126/scisignal.aat4285 [miTarget™ 3′ UTR clone]
- Mokhlis, A., et al. (2018). The modulatory role of microRNA-873 in progression of KRAS-driven cancers. Molecular Therapy: Nucleic Acid doi: 10.1016/j.omtn.2018.11.019 [miTarget™ KRAS 3′ UTR clone]
- Lin, L., et al. (2018). MicroRNA‐186 is associated with hypoxia‐inducible factor‐1α expression in chronic obstructive pulmonary disease. Molecular Genetics & Genomic Medicine doi: 10.1002/mgg3.531 [miTarget™ 3′ UTR clone]
- Williams, A.L., et al. (2018). HIF1 regulation of miR-29c impairs SERCA2 expression and cardiac contractility. Heart and Circulatory Physiology doi: 10.1152/ajpheart.00617.2018 [miTarget™ 3′ UTR clone]
- Zhang, H.G., et al. (2018). EDIBLE PLANT-DERIVED MICROVESICLE COMPOSITIONS FOR DELIVERY OF miRNA AND METHODS FOR TREATMENT OF CANCER. United States Patent Application 15/740,591 [miTarget™ IRF2 3′ UTR clone]
- Guan, Y., et al. (2018). NUAK1 knockdown suppresses prostate cancer cell epithelial-mesenchymal transition, migration, and invasion through microRNA-30b-5p .Int J Clin Exp Pathol 2018;11(12):5694-5704 [miTarget™ NUAK1 wild type and mutannt 3′ UTR clones]
2017
- Jia, L., et al. (2017). MiR-29c/PRKCI Regulates Axonal Growth of Dorsal Root Ganglia Neurons Under Hyperglycemia. Molecular Neurobiology doi: 10.1007/s12035-016-0374-5 [miTarget™ PRKCI 3′ UTR clone]
- Rawal, S., et al. (2017). Down-regulation of proangiogenic microRNA-126 and microRNA-132 are early modulators of diabetic cardiac microangiopathy. Cardiovascular Research doi: https://doi.org/10.1093/cvr/cvw235 [miTarget™ Spred1 and p120RasGap 3′ UTR clones]
- Codagnone, M., et al. (2017). Lipoxin A4 stimulates endothelial miR-126-5p expression and its transfer via microvesicles. FASEB Journal doi: 10.1096/fj.201600952R [miTarget™ SPRED1 3′ UTR clone]
- Colden, M., et al. (2017). MicroRNA-466 inhibits tumor growth and bone metastasis in prostate cancer by direct regulation of osteogenic transcription factor RUNX2. Cell Death & Disease doi: 10.1038/cddis.2017.15 [miTarget™ RUNX2 3′ UTR target clone]
- Jang, K., etal. (2017). VEGFA activates an epigenetic pathway upregulating ovarian cancerâ€initiating cells. EMBO Molecular Medicine doi: 10.15252/emmm.201606840 [miTarget™ BMII 3′ UTR target clone]
- Carmona, V., et al. (2017). Unravelling Endogenous MicroRNA System Dysfunction as a New Pathophysiological Mechanism in Machado-Joseph Disease. Molecular Therapy doi: 10.1016/j.ymthe.2017.01.021 [miTarget™ ATXN3 3′ UTR target clone]
- Zhang, J. et al. (2017). Up-regulation of CRKL by microRNA-335 methylation is associated with poor prognosis in gastric cancer. Cancer Cell International doi: 10.1186/s12935-017-0387-9 [miTarget™ CRKL3′ UTR target clone]
- Dal-Pra, S., et al. (2017). Demethylation of H3K27 Is Essential for the Induction of Direct Cardiac Reprogramming by miR Combo. Circulation Research doi: 10.1161/CIRCRESAHA.116.308741 [miTarget™ EZH2 3′ UTR target clone]
- Teng, Y., et al. (2017). MVP-mediated exosomal sorting of miR-193a promotes colon cancer progression. Nature Communications doi: 10.1038/ncomms14448 [miTarget™ Caprini 3′ UTR target clone]
- Golestaneh, N., et al. (2017). Biomarkers and Therapeutic Targets for Abnormal Retinal Pigment Epithelium. United States Patent Application 20170022562 [miTarget™ EZR 3′ UTR Target clone]
- Imani, S., et al. (2017). MicroRNA-34a targets epithelial to mesenchymal transition- inducing transcription factors (EMT-TFs) and inhibits breast cancer cell migration and invasion. Oncotarget February 9, 2017 [miTarget™ TWIST1 3′ UTR target clone]
- Li, P., et al. (2017). MicroRNA-218 Increases the Sensitivity of Bladder Cancer to Cisplatn by Targeting Glut1. Cellular Physiology and Biochemistry doi: 10.1159/000460505 [miTarget™ Glut1 3′ UTR target clone]
- ShemsiA.D., et al. (2017). Shear stress-regulated miR-27b controls pericyte recruitment by repressing SEMA6A and SEMA6D. Cardiovascular Research doi: 10.1093/cvr/cvx032 [miTarget™ Ang-2 3′ UTR target clone]
- Yan, W., et al. (2017). MicroRNA 424 regulates hepatocellular carcinoma cell migration via vascular endothelial growth factor A. Int J Clin Exp Pathol 2017;10(2) :2298-2306 [miTarget™ VEGFA 3 ’- UTR target clone]
- Cioffi, M., et al. (2017). The miR-25-93-106b cluster regulates tumor metastasis and immune evasion via modulation of CXCL12 and PD-L1. Oncotarget February 17, 2017 [miTarget™ Cxcl12 3 ’- UTR target clone]
- Elsafadi, M., et al., (2017). MicroRNA-4739 regulates osteogenic and adipocytic differentiation of immortalized human bone marrow stromal cells via targeting LRP3. Stem Cell Research doi: 10.1016/j.scr.2017.03.001 [miTarget™ LRP3 3′ UTR target clone]
- Dahlman, I., et al. (2017). Comprehensive functional screening of miRNAs involved in fat cell insulin sensitivity among women. Endocrinology and Metabolism doi: 10.1152/ajpendo.00251.2016 [miTarget™ ENPP1 3′ UTR target clone]
- Kumar, V.A., et al. (2017). Novel 2’/3’/5′-(R/S)-Serinyl Functionalized Oligonucleotides United States Patent Application 20170044527 [miTarget™ PDCD4 3′ UTR target clone]
- Sharma, N.M., et al. (2017). A NOVEL ROLE FOR MIR-133A IN CENTRALLY MEDIATED ACTIVATION OF THE RENIN-ANGIOTENSIN SYSTEM IN CONGESTIVE HEART FAILURE. Heart and Circulatory Physiology doi: 10.1152/ajpheart.00721.2016 [miTarget™ AGT 3′ UTR target clone]
- Yin, K., et al. (2017). MiR-153 Regulates Amelogenesis by Targeting Endocytotic and Endosomal/lysosomal Pathways–Novel Insight into the Origins of Enamel Pathologies. Scientific Reports doi: doi:10.1038/srep44118 [miTarget™ Cltc, Clcn4 and Slc4a4 3′ UTR target clones]
- Hori, D., et al. (2017). miR-181b regulates vascular stiffness age dependently in part by regulating TGF-β signaling. PLoS ONE doi:10.1371/journal.pone.0174108 [miTarget™ TGF-βi 3′ UTR target clone]
- Wen, L., et al. (2017). MicroRNA-148b regulates megalin expression and is associated with receptor downregulation in mice with unilateral ureteral obstruction. American Journal of Physiology doi: 10.1152/ajprenal.00585.2016 [miTarget™ megalin 3′ UTR target clone]
- Aldahmash, A., et al. (2017). MicroRNA-4739 regulates osteogenic and adipocytic differentiation of immortalized human bone marrow stromal cells via targeting LRP3. Stem Cell Research doi: 10.1016/j.scr.2017.03.001 [miTarget™ LRP3 3′ UTR target clone]
- Mohr, S., et al. (2017). Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid Leukemia. Cancer Cell doi: 10.1016/j.ccell.2017.03.001 [miTarget™ Syk 3′ UTR target clone]
- Liu, X., et al. (2017). AdipoR1-mediated miR-3908 inhibits glioblastoma tumorigenicity through downregulation of STAT2 associated with the AMPK/SIRT1 pathway. Oncology Reports doi: 10.3892/or.2017.5589 [miTarget™ STAT2 and AdipoR1 3′ UTR target clones]
- Stevanato, L., et al. (2017). MicroRNA Expression Profiling by PCR Array in 2D and 3D Differentiated Neural Culture Systems and Target Validation. Neuopromethods doi: 10.1007/7657_2017_1 [miTarget™ NR4A3 and SOX5 3′ UTR target clones]
- Kim, M., et al. (2017). VEGFA links self-renewal and metastasis by inducing Sox2 to repress miR-452, driving Slug. Oncogene doi: 10.1038/onc.2017.4 [miTarget™ SNAI2 3′ UTR target clone]
- Bruckmueller, H., et al. (2017). Clinically relevant multidrug transporters are regulated by microRNAs along the human intestine. Molecular Pharmaceutics doi: 10.1021/acs.molpharmaceut.7b00076 [miTarget™ ABCB1, ABCC3, ABCG2, PEPT1 3′ UTR target clones]
- Zahedi, F. (2017). Role of Dicer in smooth muscle cells during neointima formation. Ph.D. Thesis, University of Munich [miTarget™ ARHGEF26 3′ UTR target clone]
- Zheng, Z., et al. (2017). MiR-125b regulates proliferation and apoptosis of nasopharyngeal carcinoma by targeting A20/NF-κB signaling pathway. Cell Death & Disease doi: 10.1038/cddis.2017.211 [miTarget™ Gfap 3′ UTR target clone]
- Abidin, S.Z., et al. (2017). In Silico Prediction and Validation of Gfap as an miR-3099 Target in Mouse Brain. Neuroscience Bulletin doi: 10.1007/s12264-017-0143-0 [miTarget™ wld type and mutant A20 3′ UTR target clones]
- Heggermont, W.A., et al. (2017). Inhibition of MicroRNA-146A and Overexpression of its Target Dihydrolipoyl Succinyltransferase Protect Against Pressure-Overload Induced Cardiac Hypertrophy and Dysfunction. Circulation doi: 10.1161/CIRCULATIONAHA.116.024171 [miTarget™ DLST 3′ UTR target clone]
- Wang, J., et al. (2017). miR-629-3p may serve as a novel biomarker and potential therapeutic target for lung metastases of triple-negative breast cancer. Breast Cancer Research doi: 10.1186/s13058-017-0865-y [miTarget™ miR-629-3p lentiviral 3′ UTR target clone]
- Al-Khalaf, H.H., et al. (2017). Obesity and p16INK4A down-regulation activate breast adipocytes and promote their pro-tumorigenicity. Molecular and Cellular Biology doi: 10.1128/MCB.00101-17 [miTarget™ LEP wild type and mutant 3′ UTR target clones]
- Pandey, R., et al. (2017). MicroRNA-1825 induces proliferation of adult cardiomyocytes and promotes cardiac regeneration post ischemic injury. Am J Transl Res 2017;9(6):3120-3137 [miTarget™ 3′ UTR target clones]
- Gu, J.F., et al. (2017). Overexpression of miR-599 is associated with metastasis in colorectal cancer via inhibition of SATB2. Int J Clin Exp Pathol 2017;10(6):6701-6709 [miTarget™ SATB2 3′ UTR target clone]
- Valentino, A., et al. (2017). Deregulation of MicroRNAs mediated control of carnitine cycle in prostate cancer: molecular basis and pathophysiological consequences. Oncogene doi: 10.1038/onc.2017.216 [miTarget™ CPT1A, CACT, and CrAT 3′ UTR target clones]
- Qian, H., et al. (2017). MicroRNA-26a inhibits the growth and invasiveness of malignant melanoma and directly targets on MITF gene. Cell Death Discover doi: 10.1038/cddiscovery.2017.28 [miTarget™ MITF 3′ UTR target clone]
- Zhang, N.S., et al. (2017). MicroRNA-29 family functions as a tumor suppressor by targeting RPS15A and regulating cell cycle in hepatocellular carcinoma. Int J Clin Exp Pathol 2017;10(7):8031-8042 [miTarget™ RPS15A wild type and mutant 3′ UTR target clones]
- Muluhngwi, P. (2017). Role of MIR-29B-1 and MIR -29A in endocrine- resistant breast cancer. Ph.D. Thesis, University of Louisville. [miTarget™ ATP5G1, ATPIF1 3’UTR target clones]
- Chu, S., et al. (2017). miR-93 and PTEN: Key regulators of doxorubi…-resistance and EMT in breast cancer. Oncology Reports doi: 10.3892/or.2017.5859 [miTarget™ PTEN 3’UTR target clone]
- Lisi, V., et al. (2017). Enhanced Neuronal Regeneration in the CAST/Ei Mouse Strain Is Linked to Expression of Differentiation Markers after Injury. Cell Reports doi: 10.1016/j.celrep.2017.07.010 [miTarget™ Ascl1 3’UTR target clone]
- Ceolotto, G., et al. (2017). miR-30c-5p regulates macrophage-mediated inflammation and pro-atherosclerosis pathways. Cardiovascular Research doi: 10.1093/cvr/cvx157 [miTarget™ CASP3 wild type and mutant 3’UTR target clones]
- Mysore, R., et al. (2017). MicroRNA-221-3p regulates Angiopoietin-like 8 (ANGPTL8) expression in adipocytes. The Journal of Clinical Endocrinology and Metabolism doi: 10.1210/jc.2017-00453 [miTarget™ ANGPTL8 3’UTR target clone]
- Kwon, H., et al. (2017). Epigenetic Silencing of miRNA-34a in Human Cholangiocarcinoma via EZH2 and DNA Methylation: Impact on Regulation of Notch Pathway. The American Journal of Pathology doi: 10.1016/j.ajpath.2017.06.014 [miTarget™ 3’UTR target clones]
- Yin, J., et al. (2017). MicroRNA‑1288 promotes cell proliferation of human glioblastoma cells by repressing ubiquitin carboxyl‑terminal hydrolase CYLD expression. Molecular Medicine Reports doi:10.3892/mmr.2017.7481 [miTarget™ 3’CYLD UTR target clone]
- Zhou, N., et al. (2017). Decreased expression of hsa‑miR‑372 predicts poor prognosis in patients with gallbladder cancer by affecting chloride intracellular channel 1. Molecular Medicine Reports doi: https://doi.org/10.3892/mmr.2017.7520 [miTarget™ mutant CLIC1 3′-UTR clone]
- Dewi, I.S., et al. (2017). Non-invasive Rejection Surveillance after Heart Transplantation. Ph.D. Thesis, Lund University [miTarget™ miR-142-3p 3′-UTR clone]
- Xu, Q., et al. (2017). miR-27a induced by colon cancer cells in HLECs promotes lymphangiogenes is by targeting SMAD4. PLOS ONE doi: 10.137 1/journal.po ne.01867 18 [miTarget™ SMAD4 3′-UTR clone]
- Wu, J., et al. (2017). MicroRNA‑27a promotes tumorigenesis via targeting AKT in triple negative breast cancer. Molecular Medicine Reports doi: 10.3892/mmr.2017.7886 [miTarget™ PTEN, BAX 3′-UTR clones]
- Martinez-Barquero, V., et al. (2017). Are IL18RAP gene polymorphisms associated with body mass regulation? A cross-sectional study. BMJ Open doi: 10.1136/bmjopen-2017-017875 [miTarget™ IL18RAP wild type and mutant 3′-UTR clones]
- Bartoszewska, S., et al. (2017). miR-200b downregulates CFTR during hypoxia in human lung epithelial cells. Cellular and Molecular Biology Letters doi: 10.1186/s11658-017-0054-0 [miTarget™ CFTR 3′-UTR clone]
- Wohl, S.G., et al. (2017). Müller glial microRNAs are required for the maintenance of glial homeostasis and retinal architecture. Nature Communications doi: 10.1038/s41467-017-01624-y [miTarget™ Bcan 3′-UTR clone]
- Fan, F., et al. (2017). MicroRNA-26b-5p regulates cell proliferation, invasion and metastasis in human intrahepatic cholangiocarcinoma by targeting S100A7. Oncology Letters doi: 10.3892/ol.2017.7331 [miTarget™ S100A7 3′-UTR clone]
- Ding, D., et al. (2017). miR-613 inhibits gastric cancer progression through repressing brain derived neurotrophic factor. Experimental and Therapeutic Medicine doi: 10.3892/etm.2017.5546 [miTarget™ BDNF 3′-UTR clone]
- Sidi, Y., et al. (2017). PREVENTING AND TREATING INFLAMMATORY SKIN DISEASES. United States Patent Application 20170335328 [miTarget™ IL22RA, IL10RB, 17RA 3′-UTR clones]
- Belarbi, Y., et al. (2017). MicroRNAs-361-5p and miR-574-5p associate with human adipose morphology and regulate EBF1 expression in white adipose tissue. Molecular and Cellular Endocrinology doi: 10.1016/j.mce.2017.11.018 [miTarget™ EF1 3′-UTR clone]
- Fouad, M. (2017) THE EPIGENETIC REGULATION OF OSTEOACTIV IN/GPNMB IN BONE CELLS. Ph.D. Thesis, Kent State University [miTarget™ GPNMB 3′-UTR clone]
- Kabir, F.L., et al. (2017). microRNA-145 Antagonism Reverses TGF-β Inhibition of F508del CFTR Correction in Airway Epithelia. American Journal of Respiratory and Critical Care Medicine doi: 10.1164/rccm.201704-0732OC [miTarget™ CFTR 3′-UTR clone]
- Jung, Y.Y., et al. (2017). Atherosclerosis is exacerbated by chitinase -3-like -1 in amyloid precursor protein transgenic mice. Theranostics doi: 10.7150/ thno .20183 [miTarget™ Chi3l1 3′-UTR clone]
- Li, Y., et al. (2017). Central role of myeloid MCPIP1 in protecting against LPS-induced inflammation and lung injury. Signal Transduction and Targeted Therapy doi: 10.1038/sigtrans.2017.66 [miTarget™ EBPδ 3′-UTR clone]
- Hussein, H.A.M., et al. 2017). miRNA-36 inhibits KSHV, EBV, HSV-2 infection of cells via stifling expression of interferon induced transmembrane protein 1 (IFITM1). Scientific Reports doi: 10.1038/s41598-017-18225-w [miTarget™ IFITM1 3′-UTR clone]
- Cheng, L., et al. (2017). miR-494 inhibits cervical cancer cell proliferation through upregulation of SOCS6 expression. Oncology Letters doi: 10.3892/ol.2017.7651 [miTarget™ SOCS6 3′-UTR clone]
- Xiong, K., et al. (2017). MicroRNA‑9 functions as a tumor suppressor and enhances radio‑sensitivity in radio‑resistant A549 cells by targeting neuropilin 1. Oncology Letters doi: 10.3892/ol.2017.7705 [pEZX-MT05 3′ UTR cloning vector]
- Gill, P., et al. (2017). MicroRNA regulation of CYP 1A2, CYP3A4 and CYP2E1 expression in acetaminophen toxicity. Scientific Reports doi: 10.1038/s41598-017-11811-y [miTarget™ CYP1A2 and CYP3A4 3′-UTR clones]
2016
- Jalabert, A. et al. (2016) Exosome-like vesicles released from lipid-induced insulin-resistant muscles modulate gene expression and proliferation of beta recipient cells in mice. Diabetologia,May 2016, Volume 59, Issue 5, pp 1049-1058. [pEZX- MT01 vector containing the 3′-UTR segment of Ptch1]
- Tenga, A. et al. (2016) Regulation of Nuclear Receptor Nur77 by miR-124. PLoS ONE,DOI:10.1371/journal.pone.0148433. [Nur77-3’UTR reporter plasmid]
- Shenoda, BB. et al. (2016) Hsa-miR-34a mediated repression of corticotrophin releasing hormone receptor 1 regulates pro-opiomelanocortin expression in patients with complex regional pain syndrome. Journal of Translational Medicine,DOI: 10.1186/s12967-016-0820-1. [CRHR1 (HmiT060383) and the precursor miRNA expression clone miR-34a (HmiR0005)]
- Wang , X. et al. (2016) miR-124 inhibits cell proliferation, migration and invasion by directly targeting SOX9 in lung adenocarcinoma. Oncology
Reports,Pages: 3115-3121 DOI: 10.3892/or.2016.4648. [pEZX-SOX9 vector ] - Gjymishka , A. et al. (2016) miR-133b Regulation of Connective Tissue Growth Factor: A Novel Mechanism in Liver Pathology. The American Journal of Pathology,doi:10.1016/j.ajpath.2015.12.022. [per CTGF 3′UTR containing plasmid]
- Su, M., et al. (2016). miR-346 and miR-582-3p-regulated EG-VEGF expression and trophoblast invasion via matrix metalloproteinases 2 and 9. BioFactors doi: 10.1002/biof.1325 [human human EG-VEGF 3′ UTR target clone]
- Zahedi, F. et al. (2016). Dicer generates a regulatory microRNA network in smooth muscle cells that limits neointima formation during vascular repair. Cellular and Molecular Life Sciences doi: 10.1007/s00018-016-2349-0 [human ARHGEF26 miRNA 3′ UTR target clone]
- Chiang, C., et al. (2016). MiR-182 promotes proliferation and invasion and elevates the HIF-1α-VEGF-A axis in breast cancer cells by targeting FBXW7. American Journal of Cancer Research 6, 1785 [miR-182 3′ UTR target clone]
- Viñas, J.L., et al. (2016). Transfer of microRNA-486-5p from human endothelial colony forming cell–derived exosomes reduces ischemic kidney injury. Kidney International doi: 10.1016/j.kint.2016.07.015 [PTEN 3′UTR target clone]
- Chiabotto, G., et al. (2016). Mesenchymal Stromal Cells Epithelial Transition Induced by Renal Tubular Cells-Derived Extracellular Vesicles. PLoS ONE doi: 10.1371/journal.pone.0159163 [human CCND1 IGF1R 3′ UTR target clones]
- Bao, L., et al. (2016). Role of microRNA-4458 in patients with non-small-cell lung cancer. Oncology Letters doi: 10.3892/ol.2016.5176 [miTarget™ human CCND1 3′ UTR target clone]
- Das, D.K., et al. (2016). miR-1207-3p regulates the androgen receptor in prostate cancer via FNDC1/fibronectin. Experimental Cell Research doi: 10.1016/j.yexcr.2016.09.021 [miTarget™ human FNDC1 3’UTR target clone]
- Chen, S., et al. (2016). Opposite Regulation of Chondrogenesis and Angiogenesis in Cartilage Repair ECM Materials under Hypoxia. Journal of Materials Science & Technology doi: 10.1016/j.jmst.2016.08.001 [miTarget™ human wild-type and mutant VEGFα 3′-UTR clones]
- Alderman, C., et al. (2016). MicroRNA-15a inhibits the growth and invasiveness of malignant melanoma and directly targets on CDCA4 gene. Tumor Biology doi: 10.1007/s13277-016-5271-z [miTarget™ mouse CDCA4 3’UTR target clone]
- McDonald, M.K., et al. (2016). Regulation of proinflammatory genes by the circulating microRNA hsa-miR-939. Scientific Reports doi: 10.1038/srep30976 [miTarget™ IL-6, VEGFA, and NFκB2 3′-UTR clones]
- Zhou, J.H., et al. (2016). MicroRNA-27a-mediated repression of cysteine-rich secretory protein 2 translation in asthenoteratozoospermic patients. Asian Journal of Andrology 2016 Oct 12 [miTarget™ CRISP2 3′- UTR clone]
- Palfi, A., et al. (2016). microRNA regulatory circuits in a mouse model of inherited retinal degeneration. Scientific Reports doi: 10.1038/srep31431 [miTarget™ Mouse Rac1, Ctbp2, and Slc6a9 3′ UTR target clones]
- Ye, S.B., et al. (2016). Exosomal miR-24-3p impedes T-cell function by targeting FGF11 and serves as a potential prognostic biomarker for nasopharyngeal carcinoma. The Journal of Pathology doi: 10.1002/path.4781 [miTarget™ FGF11 3′ UTR target clone]
- Akhtar, N., et al. (2016). MicroRNA-17 Suppresses TNF-α Signaling by Interfering with TRAF2 and cIAP2 Association in Rheumatoid Arthritis Synovial Fibroblasts. The Journal of Immunology doi: 10.4049/​jimmunol.1600360 [miTarget™ ASK1 3′ UTR target clone]
- Zhou, P., et al. (2016). MiR-203 inhibits tumor invasion and metastasis in gastric cancer by ATM. Acta Biocimica et Biophysica Sinica doi: 10.1093/abbs/gmw063 [miTarget™ ATM 3′ UTR target clone]
- Fujii, T., et al. (2016). MicroRNA-331-3p Suppresses Cervical Cancer Cell Proliferation and E6/E7 Expression by Targeting NRP2. International Journal of Molecular Sciences doi: 10.3390/ijms17081351 [miTarget™ NRP2 3′ UTR target clone]
- Gu, S., et al. (2016). Functional SNP in 3′-UTR MicroRNA-Binding Site of ZNF350 Confers Risk for Age-Related Cataract. Human Mutation Variation, Informatics, and Disease doi: 10.1002/humu.23073 [miTarget™ ZNF350-A, ZNF350-G 3′ UTR target clones]
- Ramalho-Carvalho, J., et al. (2016). Epigenetic Disruption of miR-130a Promotes Prostate Cancer By Targeting SEC23B and DEPDC1. Cancer Letters doi: 10.1016/j.canlet.2016.10.028 [miTarget™ DEPDC1, SEC23B 3′ UTR target clones]
- Babu, S.S., et al. (2016). MicroRNA-126 overexpression rescues diabetes-induced impairment in efferocytosis of apoptotic cardiomyocytes. Scientific Reports doi: 10.1038/srep36207. [miTarget™ ADAM9 3′ UTR target clone]
- Jiang, Y., et al. (2016). The Role of miR-182-5p in Hepatocarcinogenesis of Trichloroethylene in Mice, Toxicologocal Sciences doi: 10.1093/toxsci/kfw246 [miTarget™ Cited2 3′ UTR target clone]
- Meerson, A., et al. (2016). Leptin and insulin up-regulate miR-4443 to suppress NCOA1 and TRAF4, and decrease the invasiveness of human colon cancer cells. BMC Cancer doi: 10.1186/s12885-016-2938-1 [miTarget™ TRAF4, NCOA1 3′ UTR Target clones]
- Mishra, P.J., et al. (2016). Integrated Genomics Identifies miR-32/MCL-1 Pathway as a Critical Driver of Melanomagenesis: Implications for miR-Replacement and Combination Therapy. PLoSONE doi: 10.1371/journal.pone.0165102 [MCL-1 (MCL-1wt and MCL-1mut), PIK3R3wt and NRAS (miTarget™ NRASwt and NRASmut 3′ UTR Target clones]
- Kureel, J., et al. (2016) MicroRNA-467g inhibits new bone regeneration by targeting Ihh/Runx-2 signaling. The International Journal of Biochemistry & Cell Biology doi: 10.1016/j.biocel.2017.01.018 [miTarget™ microRNA-467g 3′ UTR Target clone]
- Bai, J.W., et al. (2016). Down-regulation of microRNA-143 is associated with colorectal cancer progression. Eur Rev Med Pharmacol Sci 2016; 20 (22): 4682-4687 [miTarget™ ERBB3 3′ UTR Target clone]
- D’Adamo, S., et al. (2016). Hydroxytyrosol modulates the levels of microRNA-9 and its target sirtuin-1 thereby counteracting oxidative stress-induced chondrocyte death. Osteoarthritis and Cartilage doi: 10.1016/j.joca.2016.11.014 [miTarget™ SIRT1 3′ UTR Target clone]
- Ge, L., et al. (2016). miR-323a-3p regulates lung fibrosis by targeting multiple profibrotic pathways. JCI Insight doi: 10.1172/jci.insight.90301 [miTarget™ CASP3 3′ UTR Target clone]
- Yang, J., et al. (2016). Inhibition of KPNA4 attenuates prostate cancer metastasis. Oncogene doi: 10.1038/onc.2016.440 [miTarget™ KPNA4 3′ UTR Target clone]
- Xu, J., et al. (2016). miR-367 promotes the proliferation and invasion of non-small cell lung cancer via targeting FBXW7. Oncology Reports doi: 10.3892/or.2016.5314 [miTarget™ FBXw7 3′ UTR Target clone]
2015
- De Carolis, S. et al. (2015) Carbonic anhydrase 9 mRNA/microRNA34a interplay in hypoxic human mammospheres. Journal of Cellular Physiology,DOI: 10.1002/jcp.25245. [CA9-3’UTR vector, pEZX-MT01-CA9-3’UTR thymidine kinase Renilla luciferase reporter plasmid ]
- Demolli, S. et al. (2015) MicroRNA-30 mediates anti-inflammatory effects of shear stress and KLF2 via repression of angiopoietin 2. Journal of Molecular and Cellular Cardiology,Volume 88, November 2015, Pages 111–119. [Ang2 3’UTR target clone]
- Chuang, TD. et al. (2015) Mechanisms underlying aberrant expression of miR-29c in uterine leiomyoma. Fertility and Sterility,DOI: http://dx.doi.org/10.1016/j.fertnstert.2015.09.020. [3′ UTR sequences for COL3A1 or DNMT3A ]
- Smith, PY. et al. (2015) miR-132/212 deficiency impairs tau metabolism and promotes pathological aggregation in vivo. Human Molecular Genetics,doi: 10.1093/hmg/ddv377. [MmiT025143b- MT01]
- YONEYAMA, K. et al. (2015) miR-200a, miR-200b and miR-429 Are Onco-miRs that Target the PTEN Gene in Endometrioid Endometrial Carcinoma. Anticancer Research,Anticancer ResearchMarch 2015 vol. 35no. 3 1401-1410. [luciferase reporter construct containing the 3′-UTR of PTEN (HmiT015535)]
- Shinozaki-Ushiku, A. et al. (2015) Profiling of Virus-encoded MicroRNAs in Epstein-Barr Virus-associated Gastric Carcinoma and their Roles in Gastric Carcinogenesis. Journal of Virology,doi:10.1128/JVI.03639-14JVI.03639-14. [pEZX-MT01 vector containing 3′ UTR fragment of BID ]
- Li, L. et al. (2015) Overexpression of SIRT1 Induced by Resveratrol and Inhibitor of miR-204 Suppresses Activation and Proliferation of Microglia. Journal of Molecular Neuroscience,August 2015, Volume 56, Issue 4, pp 858-867. [3′ UTR luciferase reporter DNA constructs of SIRT1 (HmiT017704- MT05) ]
- Jeon, MJ. et al. (2015) MicroRNAâ€30d and microRNAâ€181a regulate HOXA11 expression in the uterosacral ligaments and are overexpressed in pelvic organ prolapse. Journal of Cellular and Molecular Medicine,DOI: 10.1111/jcmm.12448. [miTarget miRNA 3′-UTR target clones (HmiT008983-MT01)]
- Zhang, J. et al. (2015) MicroRNAâ€155â€mediated control of heme oxygenase 1 (HOâ€1) is required for restoring adaptivelyâ€tolerant CD4+ Tâ€cell function in rodents. European Journal of Immunology,DOI: 10.1002/eji.201445066. [mouse heme oxygenase 1 3’UTR]
- Ahmad, A. et al. (2015) Functional role of miR-10b in tamoxfen resistance of ER-positive breast cancer cells through down-regulation of HDAC4. BMC Cancer,DOI: 10.1186/s12885-015-1561-x. [HDAC4 3′UTR luciferase vector]
- Drakaki, A. et al. (2015) Functional microRNA high throughput screening reveals miR-9 as a central regulator of liver oncogenesis by affecting the PPARA-CDH1 pathway. BMC Cancer,DOI: 10.1186/s12885-015-1562-9. [HmiT054001-MT06]
- Yang, J. et al. (2015) Metformn induces ER stress-dependent apoptosis through miR-708-5p/NNAT pathway in prostate cancer. Oncogenesis,Oncogenesis (2015) 4, e158; doi:10.1038/oncsis.2015.18. [NNAT 3-UTR reporter construct (HmiT011847-MT01) ]
- Chen, M. et al. (2015) The NS5A Protein of Hepatitis C Virus Transcriptionally Upregulates the AGR3 Gene Expression. The Kobe journal of medical sciences, The Kobe journal of medical sciences 61(1):E27-35. [human AGR3 promoter-luciferase reporter plasmid pAGR3-GLuc ]
- Hommers, L. et al. (2015) MicroRNA hsaâ€miRâ€4717â€5p regulates RGS2 and may be a risk factor for anxietyâ€related traits. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics,DOI: 10.1002/ajmg.b.32312. [ MT01, HmiT002409-MT01, HmiT002971-MT01, HmiT054898-MT01, HmiT054457-MT01,HmiT011007-MT01, HmiT002121-MT01, HmiT009120-MT01, HmiT056011-MT01,HmiT023116-MT01, HmiT057799-MT01, HmiT011129-MT01; MmiT054664-MT01;]
- Mysore , R. et al. (2015) MicroRNA-192* impairs adipocyte triglyceride storage. Biochimica et Biophysica Acta (BBA) – Molecular and Cell Biology of Lipids,doi:10.1016/j.bbalip.2015.12.019. [SCD (HmiT016583-MT06) and ALDH3A2 (HmiT005407-MT06) 3’UTR luciferase constructs ]
- Peng, J. et al. (2015) let-7b and let-7c are determinants of intrinsic chemoresistance in renal cell carcinoma. World Journal of Surgical Oncology,DOI 10.1186/s12957-015-0596-4. [Luciferase assay The Akt2 3′-UTR and control vectors ]
- Li, L. et al. (2015) Inhibition of miR-146b expression increases Radioiodine-sensitivity in poorly differential thyroid carcinoma via positively regulating NIS expression. Biochemical and Biophysical Research Communications,doi:10.1016/j.bbrc.2015.04.134. [ FTC-133 cells were transfected with plasmid containing
firefly luciferase-hNIS-3’UTR] - Qu, JQ. et al. (2015) MiRNA-203 reduces nasopharyngeal carcinoma radioresistance by targeting IL-8/AKT signaling. Molecular Cancer Therapeutics,Published OnlineFirst August 24, 2015; doi: 10.1158/1535-7163.MCT-15-0461. [ ILY8 3’UTR of (CmiT000001YMT01)]
- Wu , L. et al. (2015) miR‑96 induces cisplatn chemoresistance in non‑small cell lung cancer cells by downregulating SAMD9. Oncology Letters,Pages: 945-952 DOI: 10.3892/ol.2015.4000. [Human SAMD9 (HmiT013716) and the LucPair Duo Luciferase Assay kit (LPFR‑M010)]
- Ma, N. et al. (2015) MicroRNA-129-5p inhibits hepatocellular carcinoma cell metastasis and invasion via targeting ETS1. Biochemical and Biophysical Research Communications,doi:10.1016/j.bbrc.2015.04.075. [ETS1 mRNA 3′-UTR clones]
- Tan, JYL. et al. (2015) Identification of Cellular Targets of MicroRNA-181a in HepG2 Cells: A New Approach for Functional Analysis of MicroRNAs. PloS one,Published: April 22, 2015http://dx.doi.org/10.1371/journal.pone.0123167. [3′ UTR of CDKN1β and E2F7 cloned downstream of the secreted firefly luciferase reporter gene]
- Kyrychenko, S. et al. (2015) Pivotal role of miR-448 in the development of ROS-induced cardiomyopathy. Cardiovascular Research,DOI: 10.1093/cvr/cvv238 . [Ncf1 3′- UTR, mutated Ncf1 3′-UTR, or control and Secre-PairTM Dual- Luciferase Reporter Assay ]
- Chuang , TD. et al. (2015) miR-29c Induction Contributes to Down-Regulation of Vascular Extracellular Matrix Proteins by Glucocorticoids. American Journal of Physiology, DOI: 10.1152/ajpcell.00254.2014. [3’UTR sequence for Col3A1, Col4A5, MMP2. luciferase assay kit]
- Martino, MT Di. et al. (2015) Functional Analysis of microRNA in Multiple Myeloma. Methods in Molecular Biology,DOI
10.1007/7651_2015_250. [pEZX-MT01, Luciferase reporters] - Costa-Pinheiro, P. et al. (2015) MicroRNA-375 plays a dual role in prostate carcinogenesis. Clinical Epigenetics,DOI 10.1186/s13148-015-0076-2. [Luciferase assay A reporter construct containing a binding site at CCND2 3′UTR for miR-375]
2014
- Kantharidis, P. et al. (2014) The study of microRNA in diabetic nephropathy: isolation, quantification and biological function. Nephrology,DOI: 10.1111/nep.12374. [3’UTR-reporter constructs]
- Liu, D. et al. (2014) MicroRNA-495 regulates the proliferation and apoptosis of human umbilical vein endothelial cells by targeting chemokine CCL2. Thrombosis Research,DOI: http://dx.doi.org/10.1016/j.thromres.2014.10.027. [CCL2 target clone]
2013
- Kulyté, A. et al (2013) Additive effects of miRNAs and transcription factors on CCL2 production in human white adipose tissue. Diabetes, Published online before print December 30, 2013, doi: 10.2337/db13-0702 . [3’UTR of SP1].
- Sturrock, A. et al (2013) Key role of microRNA in the regulation of Granulocyte-macrophage colony stimulating factor expression in murine alveolar epithelial cells during oxidative stress. The Journal of Biological Chemistry, First Published on December 26, 2013, doi: 10.1074/jbc.M113.535922 jbc.M113.535922.. [dual- reporter expression clone of murine GM-CSF 3′ UTR].
- Xu, S. et al (2013) Micrornas as new therapeutic targets for the prevention and/or treatment of retinopathy. United States Patent Application, US20130331436 A1. [Luciferase target reporter vector, pEZX-MT01].
- Ubhi, K. et al (2013) Widespread microRNA dysregulation in multiple system atrophy–diseaseâ€related alteration in miRâ€96. European Journal of Neuroscience, first published online: 5 DEC 2013 DOI: 10.1111/ejn.12444. [Reporter clones].
- Loyer, X. et al (2013) Inhibition of microRNA-92a Prevents Endothelial Dysfunction and Atherosclerosis in Mice. Circulation Research, doi: 10.1161/​CIRCRESAHA.114.302213. [3′ UTR target clone of SOCS5].
- Liang, Y. et al (2013) Requirement of miRâ€144 in CsA Induced Proliferation and Invasion of Human Trophoblast Cells by Targeting Titin. Journal of Cellular Biochemistry, DOI: 10.1002/jcb.24710. [3′ UTR target clone].
- Feng, Y. et al (2013) Heat shock improves scaâ€1+ stem cells survival and directs ischemic cardiomyocytes towards a prosurvival phenotype via exosomal transfer: a critical role for HSF1/ …. STEM CELLS, Volume 32, Issue 2, pages 462–472, February 2014. [pEZX-MT01-HSP70-3’UTR target clone].
- Ratovitski, EA. et al (2013) Phospho-ΔNp63α regulates AQP3, ALOX12B, CASP14 and CLDN1 expression through transcription and microRNA modulation. FEBS letters, Volume 587, Issue 21, 1 November 2013, Pages 3581–3586. [HmiT006376-MT01].
- Robinson, PM. et al (2013) MicroRNA Signature in Wound Healing Following Excimer Laser Ablation: Role of miR-133b on TGFβ1, CTGF, SMA, and COL1A1 Expression Levels in Rabbit …. Investigative Ophthalmology & visual science, October 23, 2013 vol. 54 no. 10 6944-6951. [3′ UTR target clones of CTGF and TGFβ1].
- Yu, B. et al (2013) Enhanced mesenchymal stem cell survival induced by GATA-4 overexpression is partially mediated by regulation of the miR-15 family. The International Journal of Biochemistry & Cell Biology, Volume 45, Issue 12, December 2013, Pages 2724–2735. [3’UTR OF Bcl-2l2 (Bcl-w)].
- Lindenbergh-van, Marlon. et al (2013) Identification of lethal microRNAs specific for head and neck cancer. Clinical Cancer Research, Clin Cancer Res October 15, 201319; 5647. [Luciferase reporter construct containing the 3’UTR sequence of ATM].
- Shukla, U. et al (2013) Insights into insulin-mediated regulation of CYP2E1: miR 132/212 targeting of CYP2E1 and role of PI3-K, Akt, mTOR signaling in regulating miR132/212 and miR 122/ …. Drug Metabolism & Disposition, doi:10.1124/dmd.113.052860. [Scrambled control expression vector (CmiR0001-MR04), Luc-Pair miR luciferase assay ].
- Kubo, Eri. et al (2013) Dynamic and differential regulation in the microRNA expression in the developing and mature cataractous rat lens. Journal of Cellular and Molecular Medicine, Volume 17, Issue 9, pages 1146–1159, September 2013. [TM2β 3′-UTR miRNA Target clone].
- Lin, HY. et al (2013) STAT3 upregulates miR-92a to inhibit RECK expression and to promote invasiveness of lung cancer cells. British Journal of Cancer, (2013) 109, 731–738.. [Control reporter and 3′-UTR reporter plasmid of RECK gene].
- Bier, A. et al (2013) MicroRNA-137 is downregulated in glioblastoma and inhibits the stemness of glioma stem cells by targeting RTVP-1. Oncotarget, Oncotarget. 2013 May; 4(5): 665–676. [plasmids expressing RTVP-1 and luciferase-RTVP-1-3’UTR].
- Ling, S . et al (2013) Dickkopf-1 (DKK1) phosphatase and tensin homolog on chromosome 10 (PTEN) crosstalk via microRNA interference in the diabetic heart. Basic Research in Cardiology, May 2013, 108:352. [Luc-PairTM miR Luciferase Assay Kit].
- Qu, Y. et al (2013) MiRâ€182 and miRâ€203 induce mesenchymal to epithelial transition and selfâ€sufficiency of growth signals via repressing SNAI2 in prostate cells. International Journal of Cancer, DOI: 10.1002/ijc.28056. [3′-UTR of SNAI2 in the pEZX-MT01 vector]
- Sundaram, G. et al (2013) /See-saw/’expression of microRNA-198 and FSTL1 from a single transcript in wound healing. Nature, 495, 103-106. doi:10.1038/nature11890 [3′UTR clone].
- Schrum, L. et al (2013) Treatment of Fibrosis Using Microrna 19b. U.S. Patent No. 20,130,053,429. 28 Feb. 2013. [3′UTR of TGFβRII in pEZX-MT01].
- Chiang, C. et al (2013) Up-regulation of miR-182 by β-catenin in breast cancer increases tumorigenicity and invasiveness by targeting the matrix metalloproteinase inhibitor RECK. Biochimica et Biophysica Acta, Volume 1830, Issue 4, April 2013, Pages 3067–3076. [3′UTR of RECK in pEZX-MT01].
- Wang, J. et al (2013) MicroRNA-31 controls phenotypic modulation of human vascular smooth muscle cells by regulating its target gene cellular repressor of E1A-stimulated genes. Experimental Cell Research, online 19 March 2013. [3’UTR of CREG in pEZX-MT01].
- Sengupta, J. et al (2013) MicroRNA-mediated GABA receptor subunit down-regulation in adult spinal cord following neonatal cystitis-induced chronic visceral pain in rats. PAIN, Volume 154, Issue 1, January 2013, Pages 59–70. [3′UTR of GABA Aα-1 gene in pEZX-MT01].
- Zhang, L. et al (2013) MiR-206 inhibits gastric cancer proliferation in part by repressing CyclinD2. Cancer Letters, Volume 332, Issue 1, 10 May 2013, Pages 94–101. [3′-UTR of CCND2 with miR-206].
- Dakhlallah, D. et al (2013) Epigenetic regulation of miR-17∼ 92 contributes to the pathogenesis of pulmonary fibrosis. American Journal of Respiratory and Critical Care Medicine, 187.4 (2013): 397-405. [3′ UTR of Col13a in pEZX-MT05 reporter vector].
- Devany, E. et al (2013) Positive and negative feedback loops in the p53 and mRNA 3′ processing pathways. Proceedings of the National Academy of Sciences, 110.9 (2013): 3351-3356. [Luciferase vector pEZX-MT01 with TP53 microRNA 3′ UTR target clone; catalog# HmiT054283-MT01].
- Majid, S. et al (2013) miRNA-34b Inhibits Prostate Cancer through Demethylation, Active Chromatin Modifications, and AKT Pathways. Clin Cancer Res January 1, 2013 19; 73 doi: 10.1158/1078-0432.CCR-12-2952. [3′-UTR target expression clones].
- Jin, Y. et al (2013) Evaluating the MicroRNA Targeting Sites by Luciferase Reporter Gene Assay. MicroRNA Protocols, Humana Press, 2013. 117-127. [luciferase constructs containing entire 3′-UTR].
- Makino, K. et al (2013) The Downregulation of microRNA let-7a Contributes to the Excessive Expression of Type I Collagen in Systemic and Localized Scleroderma. Journal of Immunology, doi: 10.4049/​jimmunol.1200822. [luciferase construct containing a2(I) collagen 39-UTR].
- Rolland-Turner, M. et al (2013) Adenosine Stimulates the Migration of Human Endothelial Progenitor Cells. Role ofCXCR4 and MicroRNA-150. PloS one, 8(1): e54135. doi:10.1371/journal.pone.0054135. [CXCR4 3’UTR in pEZX-MT05].
- Goretti, E. et al (2013) MicroRNA-16 affects key functions of human endothelial progenitor cells. Journal of Leukocyte Biology, doi: 10.1189/jlb.1012511 jlb.1012511. [CCND1 3’UTR].
- Klein, D. et al (2013) MicroRNA Expression in Alpha and Beta Cells of Human Pancreatic Islets. PloS one, 8(1): e55064. doi:10.1371/journal.pone.0055064. [cMaf 3′UTR in pEZX-MT01].
- Lee, H.K. et al (2013) MicroRNA-145 Is Downregulated in Glial Tumors and Regulates Glioma Cell Migration by Targeting Connective Tissue Growth Factor. PloS one, 8(2): e54652. doi:10.1371/journal.pone.0054652. [luciferase-CTGF-3′UTR].
- Rosario, R. et al. (2013) Comparative study of microRNA regulation on< i> FOXL2</i> between adult-type and juvenile-type granulosa cell tumours< i> in vitro</i>. Gynecologic Oncology, Volume 129, Issue 1, April 2013, Pages 209–215. [3’UTR target clone for FOXL2 (HmiT017665-MT01)].
2012
- Zehavi, L. et al (2012) Silencing of a large microRNA cluster on human chromosome 14q32 in melanoma: biological effects of mir-376a and mir-376c on insulin growth factor 1. Molecular Cancer 2012, 11:44. [3’UTR target clone for IGF1R (HmiT009523-MT01)].
- Muratsu-Ikeda, S. et al. (2012) Downregulation of miR-205 Modulates Cell Susceptibility to Oxidative and Endoplasmic Reticulum Stresses in Renal Tubular Cells. PLoS ONE 7(7): e41462. doi:10.1371/journal.pone.0041462. [EGLN2 3′UTR miRNA target clone].
- Amodio, N. et al. (2012) DNA-demethylating and anti-tumor activity of synthetic miR-29b mimics in multiple myeloma. Oncotarget, 3.10 (2012): 1246-1258. [3’UTRs of DNMT3a and DNMT3B].
- Fang, Y. et al. (2012) Site-Specific MicroRNA-92a Regulation of Krüppel-Like Factors 4 and 2 in Atherosusceptible Endothelium. Arteriosclerosis, Thrombosis, and Vascular Biology. 2012; 32: 979-987 [3’UTR of human KLF4 and KLF2].
- Sonkoly, E. et al. (2012) MicroRNA-203 functions as a tumor suppressor in basal cell carcinoma. Oncogenesis (2012) 1, e3; doi:10.1038/oncsis.2012.3. [3’UTR of c-JUN].
- Alla, V. et al. (2012) E2F1 confers anticancer drug resistance by targeting ABC transporter family members and Bcl-2 via the p73/DNp73-miR-205 circuitry. Cell Cycle, Volume 11, Issue 16 August 15, 2012. [3’UTR of E2F1].
- Lai, V. et al. (2012) MicroRNA-143 is a critical regulator of cell cycle activity in stem cells with co-overexpression of Akt and angiopoietin-1 via transcriptional regulation of Erk5/cyclin D1 signaling. Cell Cycle, Volume 11, Issue 4 February 15, 2012. [miR-143, 3’UTR of Erk5].
- Yang, Y. et al. (2012) Decrease of miR-122 causes hepatic insulin resistance by inducing protein tyrosine phosphatase 1B, which is reversed by licorice flavonoid. Hepatology, DOI: 10.1002/hep.25912. [3’UTR of PTP1B].
- Angel-Morales, G. et al. (2012) Red wine polyphenolics reduce the expression of inflammation markers in human colon-derived CCD-18Co myofibroblast cells: Potential role of microRNA-126. Food Funct., 2012,3, 745-752. [3’UTR of VCAM-1].
- Zehavi, L. et al. (2012) Silencing of a large microRNA cluster on humanchromosome 14q32 in melanoma: biological effects of mir-376a and mir-376c on insulin growth factor 1 receptor. Molecular Cancer 2012, 11:44. [3’UTR of IGF1R].
- Couts, K. et al. (2012) Oncogenic B-Raf signaling in melanoma cells controls a network of microRNAs with combinatorial functions. Oncogene advance online publication 2 July 2012; doi: 10.1038/onc.2012.209. [3’UTR].
- Yin, K. et al. (2012) Vascular endothelial cell-specific microRNA-15a inhibits angiogenesis in hindlimbischemia. The Journal of Biological Chemistry, 287, 27055-27064. [3′UTR of human VEGFa].
- Tanic, M. et al. (2012) Integration of BRCA1-mediated miRNA and mRNA profiles reveals microRNA regulation of TRAF2 and NFκBpathway. Breast Cancer Research and Treatment Volume 134, Number 1 (2012), 41-51, DOI: 10.1007/s10549-011-1905-4. [3’UTR of TRAF2].
- Arner, E. et al. (2012) Adipose tissue microRNAs as regulators of CCL2 production in human obesity. Diabetes August 2012 vol. 61 no. 8 1986-1993. [3′UTR of CCL2, ARNT, MAX, and RELB].
- Palumbo, T. et al. (2012) Functional screen analysis reveals miR-26b and miR-128 as central regulators of pituitary somatomammotrophic tumor growth through activation of the PTEN–AKT pathway. Oncogene, (21 May 2012) | doi:10.1038/onc.2012.190. [3’UTR of PTEN, BMI1].
- Chuang, T. et al. (2012) miR-200c is aberrantly expressed in leiomyomas in an ethnic-dependent manner and targets ZEBs, VEGFA, TIMP2, and FBLN5. Endocr Relat Cancer August 1, 2012 19 541-556. [3′ UTR of ZEB1, ZEB2, VEGFA, TIMP2, FBLN5].
- Ibrahim, S. et al. (2012) Targeting of syndecan-1 by microRNA miR-10b promotes breast cancer cell motility and invasiveness via a Rho-GTPase-and E-cadherin-dependent mechanism. International Journal of Cancer, Volume 131, Issue 6, pages E884–E896, 15 September 2012. [3’UTR of human SDC1].
- Zhuang, G. et al. (2012) Tumour-secreted miR-9 promotes endothelial cell migration and angiogenesis by activating the JAK-STAT pathway. The EMBO Journal (2012) 31, 3513 – 3523 doi:10.1038/emboj.2012.183. [3′UTR of human SOCS5].
- Lee, CG. et al. (2012) Farnesoid X receptor protects hepatocytes from injury by repressing miR-199a-3p, which increases levels of lkb1. Gastroenterology, Volume 142, Issue 5, May 2012, Pages 1206–1217.e7. [3′UTR of LKB1].
- Vickers, K. et al. (2012) MicroRNA-27b is a regulatory hub in lipid metabolism and is altered in dyslipidemia. Hepatology online: 6 JUL 2012 , DOI: 10.1002/hep.25846. [3’UTR of human GPAM].
- Li, Y. et al. (2012) Epigenetic deregulation of miR-29a and miR-1256 by isoflavone contributes to the inhibition of prostate cancer cell growth and invasion. Epigenetics Volume 7, Issue 8 August 2012. [TRIM68 3′UTR].
- Bose, D. et al. (2012) The Tuberculosis Drug Streptomycn as a Potential Cancer Therapeutic: Inhibition of miR-21 Function by Directly Targeting Its Precursor. Angewandte Chemie, Volume 124, Issue 4, pages 1043–1047, January 23, 2012. [3’UTR clone].
- Yuan, K. et al. (2012). Role of miR-148a in Hepatitis B Associated Hepatocellular Carcinoma. PLoS ONE 7(4): e35331. doi:10.1371/journal.pone.0035331. [3′UTR of miR-148a].
- Saini, S. et al. (2012) miRNA-708 Control of CD44+ Prostate Cancer–Initiating Cells. Cancer Res; 72(14); 3618–30. [3’UTR of CD44 and AKT2].
- Biyashev, et al. (2012) miR-27b controls venous specification and tip cell fate. Blood March 15, 2012 vol. 119 no. 11 2679-2687. [3’UTR of Spry2].
- Panda, H. et al. (2012) Endometrial miR-200c is altered during transformation into cancerous states and targets the expression of ZEBs, VEGFA, FLT1, IKKβ, KLF9, and FBLN5. Reproductive Sciences August 2012 vol. 19 no. 8 786-796. [3′UTR of ZEB1, ZEB2, VEGFA, FBLN5, KLF9].
- Panda, H. et al. (2012) Endometrial miR-181a and miR-98 Expression Is Altered during Transition from Normal into Cancerous State and Target PGR, PGRMC1, CYP19A1, DDX3X, and TIMP3. The Journal of Clinical Endocrinology & Metabolism July 1, 2012 vol. 97 no. 7 E1316-E1326. [3’UTR of PGRMC1 and DDX3X].
- Mackiewicz, M. et al. (2012) Identification of the receptor tyrosine kinase AXL in breast cancer as a target for the human miR-34a microRNA. Breast Cancer Research and Treatment Volume 130, Number 2 (2011), 663-679, DOI: 10.1007/s10549-011-1690-0. [3’UTR of AXL].
- Dippold, R. et al. (2012) Chronic ethanol feeding enhances miR-21 induction during liver regeneration while inhibiting proliferation in rats. AJP – GI July 12, 2012. [3’UTR].