For studying the role of miRNA or trying to validate a putative target, GeneCopoeia has the right solutions. GeneCopoeia miRNA tools will help you design effective experiments to answer your questions.
- What is the regulatory function of a specific miRNA? Do quantitative changes in its expression directly or indirectly lead to cancer or other diseases? If so, how much change?
- How can I quickly detect and measure miRNA expression levels?
- Which miRNA have an effect on my gene of interest?
- Does a particular miRNA have the same influence on the same target gene in a different cell population?
- Are there multiple targets for my miRNA? How can I validate a specific miRNA against a predicted target?
GeneCopoeia provides solutions for every step of miRNA functional analysis and detection
Overexpress or knockdown miRNA
miExpress™ precursor miRNA expression clones and miArrest™ miRNA inhibitors
Overexpression or suppression of miRNA can help identify target genes and/or study the effects of specific miRNA in cell culture models.
Once the endogenous miRNA expression level of a cell is determined, GeneCopoeia miRNA precursors or inhibitors can be used to over-express or knockdown miRNA levels and study gain-of-function or loss-of-function effects respectively.
The specific features and choices enable studies of all kinds of cells including difficult-to-transfect and non-dividing using miRNA constructs from GeneCopoeia.
- Transient or stable transfection
- Lentiviral or non-viral vector backbones
- Fluorescent reporter genes
- Choice of vector-based or synthetic oligonucleotide inhibitors
miRNA clone sets now available!
Questions? Contact us here or email directly at inquiry@genecopoeia.com.