The protein encoded by this gene is a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal.

The catalog clones for this gene do not contain the SECIS element. If you require a construct with SECIS, please email inquiry@genecopoeia.com.

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Starting from $78 for selected genes
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All human and mice ORF clones are fully sequenced using Sanger sequencing by capillary electrophoresis and Amino Acid Sequences are guaranteed to be matched with NCBI database.

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