All human and mice ORF clones and related Lentivirus, AAV particles and recombinant proteins provided by GeneCopoeia are fully sequenced using Sanger sequencing by capillary electrophoresis and Amino Acid Sequences are guaranteed to be matched with NCBI database.

Nuclear hormone receptors

Introduction

Nuclear hormone receptors refer to the target molecules of hormone action in the nucleus of the cell and belong to the nuclear receptors. Steroid hormone receptors and non-steroid hormone receptors are collectively referred to as nuclear hormone receptors.

Type I Steroid Receptors include: the estrogen receptor (ER), androgen receptor (AR), progesterone receptor (PGR), and glucocorticoid receptor (GR). Type II Non-steroid Receptors include: the thyroid hormone receptor (THR), the retinoic acid receptor (RARα), the vitamin D receptor (VDR), and the peroxidase proliferator activated receptor gamma (PPARγ). Receptors different from those on the cell surface are also known as nuclear hormone receptors.

Unlike receptors on the cell surface, these receptors are found only in postnatal animals (e.g., nematodes, insects, and vertebrates), and are mostly trans-acting factors that, when combined with the corresponding hormones, bind to cis-acting elements of DNA and regulate gene transcription, thus playing an important role in growth and development, metabolism, cellular differentiation, and many physiological processes in the body. Dysfunction of such receptors will lead to a series of diseases such as cancer, infertility, obesity, and diabetes.

Clone set information

Cat. No.	Old Cat. No.	Species	Gene	Vector	Vector Type	Price
OC-GF015-M02	OC-HNH-M02	Human	73	pReceiver-M02	Expression-ready Non-viral	Inquire
OC-GF015-M35	OC-HNH-M35	Human	73	pReceiver-M35	Expression-ready Non-viral	Inquire
OC-GF015-M98	OC-HNH-M98	Human	73	pReceiver-M98	Expression-ready Non-viral	Inquire
OC-GF015-Lv105	OC-HNH-Lv105	Human	73	pReceiver-Lv105	Expression-ready Lentiviral	Inquire
OC-GF015-Lv242	OC-HNH-Lv242	Human	73	pReceiver-Lv242	Expression-ready Lentiviral	Inquire
OC-GF015-GC	OC-HNH-GC	Human	73	pDONR™ Vector	Gateway shuttle	Inquire
OC-GF015-AV43 NEW!	/	Human	73	pEZ-AV43	Expression-ready AAV	Inquire
OC-GF015-AV31 NEW!	/	Human	73	pEZ-AV31-p40500	Expression-ready AAV	Inquire

Clone list

The form only shows 50 clones of the whole set. Please contact us at 1-301-762-0888 or inquiry@genecopoeia.com if you have any questions.

Symbol	Accession	Species	Description	ORF length(bp)	Product ID
VDR	NM_001017535.2	Human	Homo sapiens vitamin D receptor (VDR), transcript variant 2, mRNA.	1284	GC-A0043
GHRHR	NM_000823.4	Human	Homo sapiens growth hormone releasing hormone receptor (GHRHR), mRNA.	1272	GC-A0191
ESR1	NM_000125.3	Human	Homo sapiens estrogen receptor 1 (ESR1), transcript variant 1, mRNA.	1788	GC-A0322
RXRB	NM_021976.5	Human	Homo sapiens retinoid X receptor beta (RXRB), transcript variant 2, mRNA.	1602	GC-A0346
GNRHR	NM_000406.3	Human	Homo sapiens gonadotropin releasing hormone receptor (GNRHR), transcript variant 1, mRNA.	987	GC-A0455
AHR	NM_001621.5	Human	Homo sapiens aryl hydrocarbon receptor (AHR), mRNA.	2547	GC-A0474
GHR	NM_001242401.4	Human	Homo sapiens growth hormone receptor (GHR), transcript variant 4, mRNA.	1917	GC-A0521
RXRA	NM_002957.6	Human	Homo sapiens retinoid X receptor alpha (RXRA), transcript variant 1, mRNA.	1389	GC-A0529
NR0B1	NM_000475.5	Human	Homo sapiens nuclear receptor subfamily 0 group B member 1 (NR0B1), mRNA.	1413	GC-A0573
CRHR2	NM_001883.5	Human	Homo sapiens corticotropin releasing hormone receptor 2 (CRHR2), transcript variant 1, mRNA.	1236	GC-A0634
NR1D1	NM_021724.5	Human	Homo sapiens nuclear receptor subfamily 1 group D member 1 (NR1D1), mRNA.	1845	GC-A0803
THRA	NM_001190919.2	Human	Homo sapiens thyroid hormone receptor alpha (THRA), transcript variant 4, mRNA.	1473	GC-A0835
NR3C1	NM_001024094.2	Human	Homo sapiens nuclear receptor subfamily 3 group C member 1 (NR3C1), transcript variant 7, mRNA.	2337	GC-A0857
NR1I3	NM_005122.5	Human	Homo sapiens nuclear receptor subfamily 1 group I member 3 (NR1I3), transcript variant 3, mRNA.	1047	GC-A0964
TRHR	NM_003301.7	Human	Homo sapiens thyrotropin releasing hormone receptor (TRHR), mRNA.	1197	GC-A0971
NR2F1	NM_005654.6	Human	Homo sapiens nuclear receptor subfamily 2 group F member 1 (NR2F1), mRNA.	1272	GC-A1000
NR1H3	NM_005693.4	Human	Homo sapiens nuclear receptor subfamily 1 group H member 3 (NR1H3), transcript variant 1, mRNA.	1344	GC-A1306
NR2F2	NM_021005.4	Human	Homo sapiens nuclear receptor subfamily 2 group F member 2 (NR2F2), transcript variant 1, mRNA.	1245	GC-C0221
ESRRG	NM_001438.4	Human	Homo sapiens estrogen related receptor gamma (ESRRG), transcript variant 1, mRNA.	1377	GC-E0424
PPARD	NM_006238.5	Human	Homo sapiens peroxisome proliferator activated receptor delta (PPARD), transcript variant 1, mRNA.	1326	GC-G0246
RARA	NM_001145301.3	Human	Homo sapiens retinoic acid receptor alpha (RARA), transcript variant 3, mRNA.	1389	GC-H0048
NR4A2	NM_006186.4	Human	Homo sapiens nuclear receptor subfamily 4 group A member 2 (NR4A2), transcript variant 1, mRNA.	1797	GC-I0539
RXRG	NM_006917.5	Human	Homo sapiens retinoid X receptor gamma (RXRG), transcript variant 1, mRNA.	1392	GC-M0360
NR4A3	NM_173199.4	Human	Homo sapiens nuclear receptor subfamily 4 group A member 3 (NR4A3), transcript variant 4, mRNA.	1332	GC-M0934
NR1D2	NM_005126.5	Human	Homo sapiens nuclear receptor subfamily 1 group D member 2 (NR1D2), transcript variant 1, mRNA.	1740	GC-P0004
NR5A1	NM_004959.5	Human	Homo sapiens nuclear receptor subfamily 5 group A member 1 (NR5A1), mRNA.	1386	GC-P0006
NR6A1	NM_033334.4	Human	Homo sapiens nuclear receptor subfamily 6 group A member 1 (NR6A1), transcript variant 1, mRNA.	1443	GC-P0009
NR2E3	NM_014249.4	Human	Homo sapiens nuclear receptor subfamily 2 group E member 3 (NR2E3), transcript variant 2, mRNA.	1233	GC-P0012
RARB	NM_001290217.2	Human	Homo sapiens retinoic acid receptor beta (RARB), transcript variant 4, mRNA.	1011	GC-P0014
NR2E1	NM_003269.5	Human	Homo sapiens nuclear receptor subfamily 2 group E member 1 (NR2E1), transcript variant 2, mRNA.	1158	GC-P0019
PPARG	NM_015869.5	Human	Homo sapiens peroxisome proliferator activated receptor gamma (PPARG), transcript variant 2, mRNA.	1518	GC-Q0148
NR5A2	NM_003822.5	Human	Homo sapiens nuclear receptor subfamily 5 group A member 2 (NR5A2), transcript variant 2, mRNA.	1488	GC-Q0618
TRH	NM_007117.5	Human	Homo sapiens thyrotropin releasing hormone (TRH), mRNA.	729	GC-S0380
RARG	NM_000966.6	Human	Homo sapiens retinoic acid receptor gamma (RARG), transcript variant 1, mRNA.	1365	GC-T0175
NR1H4	NM_005123.4	Human	Homo sapiens nuclear receptor subfamily 1 group H member 4 (NR1H4), transcript variant 2, mRNA.	1419	GC-T0601
NR0B2	NM_021969.3	Human	Homo sapiens nuclear receptor subfamily 0 group B member 2 (NR0B2), mRNA.	774	GC-T1368
NR1I2	NM_022002.3	Human	Homo sapiens nuclear receptor subfamily 1 group I member 2 (NR1I2), transcript variant 2, mRNA.	1422	GC-T2079
RORA	NM_134261.2	Human	Homo sapiens RAR related orphan receptor A (RORA), transcript variant 1, mRNA.	1572	GC-T3100
RORC	NM_001001523.2	Human	Homo sapiens RAR related orphan receptor C (RORC), transcript variant 2, mRNA.	1494	GC-T6988
PTGER3	NM_198716.2	Human	Homo sapiens prostaglandin E receptor 3 (PTGER3), transcript variant 6, mRNA.	1125	GC-T7970
THRB	NM_001252634.2	Human	Homo sapiens thyroid hormone receptor beta (THRB), transcript variant 4, mRNA.	1386	GC-T9450
ESR2	NM_001437.3	Human	Homo sapiens estrogen receptor 2 (ESR2), transcript variant a, mRNA.	1593	GC-U0033
GHSR	NM_004122.2	Human	Homo sapiens growth hormone secretagogue receptor (GHSR), transcript variant 1b, mRNA.	870	GC-U0190
NR2E3	NM_016346.4	Human	Homo sapiens nuclear receptor subfamily 2 group E member 3 (NR2E3), transcript variant 1, mRNA.	1104	GC-X0397
GHSR	NM_198407.2	Human	Homo sapiens growth hormone secretagogue receptor (GHSR), transcript variant 1a, mRNA.	1101	GC-X0963
PTGER3	NM_198719.2	Human	Homo sapiens prostaglandin E receptor 3 (PTGER3), transcript variant 9, mRNA.	1173	GC-Y0003
PTGER3	NM_198715.3	Human	Homo sapiens prostaglandin E receptor 3 (PTGER3), transcript variant 5, mRNA.	1167	GC-Y0004
PTGER3	NM_198717.2	Human	Homo sapiens prostaglandin E receptor 3 (PTGER3), transcript variant 7, mRNA.	1098	GC-Y0005
NR1H3	NM_001130101.3	Human	Homo sapiens nuclear receptor subfamily 1 group H member 3 (NR1H3), transcript variant 2, mRNA.	1164	GC-Z0276
THRA	NM_001190918.2	Human	Homo sapiens thyroid hormone receptor alpha (THRA), transcript variant 3, mRNA.	1356	GC-Z0464