View selected publications citing GeneCopoeia’s AAV products and services from the recent literature
2024
- Bhattacharya, S., et al. (2024). Prominin-1 Knockdown Causes RPE Degeneration in a Mouse Model. Cells DOI: 10.3390/cells13211761 [AAVPrime™ AAV2/1.CMV.saCas9.U6.Prom1gRNA and AAV2/1.CMV.saCas9.U6.scrambled gRNA]
- Wang, Z., et al. (2024). TMEM176B Prevents and alleviates bleomycin-induced pulmonary fibrosis via inhibiting transforming growth factor β-Smad signaling. Heliyon. DOI: 10.1016/j.heliyon.2024.e35444 [AAVPrime™ AAV particles expressing TMEM176B]
- Falcetta, D., et al. (2024). CaMKIIβ deregulation contributes to neuromuscular junction destabilization in Myotonic Dystrophy type I. Skelet Muscle. DOI: 10.1186/s13395-024-00345-3 [AAVPrime™ AAV particles expressing Mouse Camk2b (NM_007595.6, isoform 2), Cat.No.AA09-Mm33884-AV01-A00; AAVPrime™ AAV particles expressing Mouse Camk2b (XM_006514464, isoform X1), Cat.No.AA09-Mm44818-AV01-A00; AVPrime™ AAV particles expressing EGFP, Cat.No.AA09-NEG-AV07-A00]
- Masmudi‐Martín, M., et al. (2024). Brain areas interconnected to ventral pathway circuits are independently able to induce enhancement in object recognition memory and cause reversal in object recognition memory deficit. CNS Neurosci Ther. DOI: 10.1111/cns.14727 [AAVPrime™ shRNA AAV particles targeting Ywhaz]
- Zhang, J., et al. (2024). AMPK‐upregulated microRNA‐708 plays as a suppressor of cellular senescence and aging via downregulating disabled‐2 and mTORC1 activation. MedComm (2020). DOI: 10.1002/mco2.475 [AAVPrime™ Purified Adeno-associated Viral Particles, Cat. No.AA09‐MmiR3115‐MR14‐400]
2023
- Navarro-Lobato, I., et al. (2023). Promotion of structural plasticity in area V2 of visual cortex prevents against object recognition memory deficits in aging and Alzheimer’s disease rodents. Neural Regen Res. DOI: 10.4103/1673-5374.389301 [AAVPrime™ AAV particles targeting Rat Bdnf and Mouse Bdnf, Cat. No. AA10-RSH067171-AV03-200, AA10-MSH026637-AV03-200]
- Bayan Alakhtar, et al. 2023.E-cigarette exposure causes early pro-atherogenic changes in an inducible murine model of atherosclerosis. Front Toxicol. DOI: 10.3389/ftox.2023.1244596 [AAVPrime™ AAV particles expressing mPCSK9]
- Yan Chen, et al. 2023.P-Glycoprotein Exacerbates Brain Injury Following Experimental Cerebral Ischemia by Promoting Proinflammatory Microglia Activation. Oxid Med Cell Longev. DOI: 10.1155/2023/6916819 [AAVPrime™ AAV-qPCR Titration Kit]
- Doron, G., et al. (2023). Poly(ethylene glycol)-Based Hydrogel Microcarriers Alter Secretory Activity of Genetically Modified Mesenchymal Stromal Cells. ACS Biomater Sci Eng. doi: 10.1021/acsbiomaterials.3c00954 [AAVPrime™ AAV particles expressing IL1RN]
- Hasan, K.M., et al. (2023). Fatty Acid Excess Dysregulates CARF to Initiate the Development of Hepatic Steatosis. Cells doi: 10.3390/cells12071069 [AAVPrime™ AAV particles expressing CARF and AAV-empty vector; OMICSLINK™ CARF Lentiviral ORF expression clone]
- Hasan, M.N., et al. (2023). Combining ASBT inhibitor and FGF15 treatments enhances therapeutic efficacy against cholangiopathy in female but not male Cyp2c70 KO mice. J Lipid Res doi: 10.1016/j.jlr.2023.100340 [OMICSLINK™ Fgf15 ORF expression clone; AAVPrime™ AAV particles expressing Fgf15]
2022
- Gannon, A-L., et al. (2022). A Novel Model Using AAV9-Cre to Knockout Adult Leydig Cell Gene Expression Reveals a Physiological Role of Glucocorticoid Receptor Signalling in Leydig Cell Function Int J Mol Sci doi: 10.3390/ijms232315015 [AAVPrime™ AAV particles expressing CRE and GFP]
- Chen, X., et al. (2022). Pitx3 deficiency promotes age-dependent alterations in striatal medium spiny neurons. Front Aging Neurosci doi: 10.3389/fnagi.2022.960479 [AAV-hSyn1-eGFP]
- Hogan, T.B., et al. (2022). Caveolin-1 Peptide Regulates p53-microRNA-34a Feedback in Fibrotic Lung Fibroblasts. iScience doi: 10.1016/j.isci.2022.104022 [AAVPrime™ AAV particles expressing microRNA inhibitors]
- Yang, B., et al. (2022). Evaluation of Early Biomarkers of Atherosclerosis Associated with Polychlorinated Biphenyl Exposure: An in Vitro and in Vivo Study. Environmental Health Perspectives doi: 10.1289/EHP9833 [AAVPrime™ AAV particles expressing HDAC7]
- Xia, Y., et al. (20220. Neuronal C/EBP/AEP pathway shortens life span via selective GABAnergic neuronal degeneration by FOXO repression. Science Advances doi: 10.1126/sciadv.abj8658 [AAVPrime™ AAV particles expressing FOXO1, shRNA targeting FOXO1]
- Song, M-Y., et al. (2022. Sirt6 reprograms myofibers to oxidative type through CREB-dependent Sox6 suppression. Nature Communications doi: 10.1038/s41467-022-29472-5 [AAVPrime™ AAV particles expressing Sirt6, shRNA targeting Sirt6]
- Lio, J., et al. (2022). C/EBPβ/AEP signaling couples atherosclerosis to the pathogenesis of Alzheimer’s disease. Molecular Psychiatry doi: 10.1038/s41380-022-01556-0 [AAVPrime™ AAV particles expressing shRNA targeting ApoE]
2021
- Toan, N.K., et al. (2021). Choline Acetyltransferase Induces the Functional Regeneration of the Salivary Gland in Aging SAMP1/Kl -/- Mice. International Journal of Molecular Sciences doi: 10.3390/ijms22010404 [AAVPrime™ AAV particles expressing shRNA targeting ChAT]
- Zhang, W-B., et al. (2021). Activation of Nrf2 by miR-152 Inhibits Doxorubicin-InducedCardiotoxicity via Attenuation of Oxidative Stress, Inflammation,and Apoptosis. Oxidative Medicine and Cellular Longevity doi: 10.1155/2021/8860883 [AAVPrime™ AAV particles expressing mir-152 miRNA; AAVPrime™ AAV particles expressing shRNA targeting Nrf2]
- Kang, S.S., et al. (2021). ApoE4 inhibition of VMAT2 in the locus coeruleus exacerbates Tau pathology in Alzheimer’s disease. Acta Neuropathologica doi: 10.1007/s00401-021-02315-1 [AAVPrime™ AAV particles expressing ApoE4]
- Quan, D.N. and Shiloach, J. (2021). rAAV production and titration at the microscale for high- throughput screening. Human Gene Therapy doi: 10.1089/hum.2021.080 [AAVPrime™ AAV particles expressing EGFP]
2020
- Han, L., et al. (2020). Homocysteine-induced electrical remodeling via the mediation of IP3R1/Nav1.5 signaling pathway. Am J Transl Res. 2020; 12(7): 3822–3841 [AAVPrime™ AAV particles expressing shRNA targeting IP3R1]
- Luo, Y., et al. (2020). Upregulation of circ_0000199 in circulating exosomes is associated with survival outcome in OSCC. Scientific Reports doi: 10.1038/s41598-020-70747-y [AAVPrime™ AAV particles expressing shRNA targeting circ_0000199]
- Luo, Y., et al. (2020). A novel epigenetic regulation of circFoxp1 on Foxp1 in colon cancer cells. Cell Death & Disease doi: 10.1038/s41419-020-03007-6 [AAVPrime™ AAV particles expressing shRNA targeting circ_FoxP1]
- Millett, P.J., et al. (2020). Gene Editing to Impove Joint Function. United States Patent Applicaitons doi: 20200360454K [AAVPrime™ AAV particles expressing GFP]
2019
- Zhao, Y. and Ren, J. (2019). MODIFIED IMMUNE CELLS HAVING ENHANCED FUNCTION AND METHODS FOR SCREENING FOR SAME. United States Patent Application 20190345491 [AAVPrime™ AAV particles expressing DNMT3A]