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Histones

Introduction Histones are alkaline proteins found in the chromatin of eukaryotic and prokaryotic cells, which form the structure of nucleosomes and are water-soluble together with DNA. They are mainly divided into five categories depending on their amino acid...

GPCRs

Introduction G protein-coupled receptors (GPCRs) are a large family of membrane protein receptors found only in eukaryotes. They are widely distributed in organs and tissues such as the central nervous system, immune system, cardiovascular system, and retina. GPCRs...

Epigenetics

Introduction Epigenetics is the study of heritable changes in gene function that do not involve alterations to the DNA sequence. Such changes often involve alterations that affect gene expression regulation, including DNA methylation, histone modifications, chromosome...

Drug target genes

Introduction Drug targets are biomacromolecules in the body that have pharmacodynamic functions by interacting with drugs, such as certain proteins and nucleic acids. The genes that encode target proteins are also known as target genes. The identification of target...

Immuno-oncology

Introduction Immuno-oncology is a scientific field that studies the interactions between tumors and the immune system, revealing how tumors evade the immune surveillance and elimination, as well as...

Transcription factors

Introduction Transcription factors, also known as trans-acting factors, are proteins that can bind to specific nucleotide sequences upstream of a gene, and these proteins can regulate the...

Secretory proteins

Introduction Secretory proteins are proteins that are synthesized inside the cell and then secreted outside the cell to play a role, such as salivary amylase, pepsin, digestive enzymes, antibodies...

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