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Validated All-in-One™ qPCR Primer for SOCS4(NM_199421.2) Search again
Product ID:
HQP187935
(click here to view gene annotation page)
Powered by BiozSpecies:
Human
Symbol:
Alias:
SOCS7
Gene Description:
suppressor of cytokine signaling 4
Target Gene Accession:
NM_199421.2(click here to view gene page)
Estimated Delivery:
Approximately 1-3 weeks, but may vary. Please email sales@genecopoeia.com or call 301-762-0888 to confirm ETA.
Important Note:
By default, qPCR primer pairs are designed to measure the expression level of the splice variant (accession number) you selected for this gene WITHOUT consideration of other possible variants of this gene. If this gene has multiple variants, and you would like to measure the expression levels of one particular variant, multiple variants, or all variants, please contact us for a custom service project at inquiry@genecopoeia.com.
Summary
The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling.
Gene References into function
- the expression of SOCS5 and its closest homolog SOCS4 is elevated in cells following treatment with EGF, similar to several negative feedback regulators of EGFR whose expression is up-regulated upon receptor activation.
- The structure of the SOCS4-ElonginC-ElonginB complex reveals a distinct SOCS structural class.