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Validated All-in-One™ qPCR Primer for FCRL3(NM_052939.4) Search again
Product ID:
HQP187440
(click here to view gene annotation page)
Powered by BiozSpecies:
Human
Symbol:
Alias:
CD307c, FCRH3, IFGP3, IRTA3, MAIA, SPAP2
Gene Description:
Fc receptor like 3
Target Gene Accession:
NM_052939.4(click here to view gene page)
Estimated Delivery:
Approximately 1-3 weeks, but may vary. Please email sales@genecopoeia.com or call 301-762-0888 to confirm ETA.
Important Note:
By default, qPCR primer pairs are designed to measure the expression level of the splice variant (accession number) you selected for this gene WITHOUT consideration of other possible variants of this gene. If this gene has multiple variants, and you would like to measure the expression levels of one particular variant, multiple variants, or all variants, please contact us for a custom service project at inquiry@genecopoeia.com.
Gene References into function
- molecular cloning and characterization of SPAP2
- Single nucleotide polymorphism in Graves' disease in a large UK Caucasian Graves' disease data set.
- This gene will not have a substantial effect in determining susceptibility to RArheumatoid arthritis in populations of Northern European descent.
- Susceptibility to type 1 autoimmune hepatitis in Japanese patients is not influenced by FcgammaRIIA, FcgammaRIIB, or FCRL3 polymorphisms.
- Findings from a large case-control sample of patients with alopecia areata (AA) do not support an association between FCRL3 and susceptibility to AA.
- Both the FCRL3 and PTPN22 genes play roles in rheumatoid arthritis susceptibility, but in different individuals.
- The association of the -169C/T SNP in FCRL3 with rheumatoid arthritis and systemic lupus erythematosus that was observed in Japanese patients was not replicated in a Korean population.
- Susceptibility to autoimmunity at the FCRL3 locus.
- The FCRL3 gene is involved in inflammatory bowel disease (IBD) genetic susceptibility by an epistatic interaction with HLA-DRB1*0103.
- there is an epistatic interaction between genes in chromosomes 6p21 and 1q21-22, marked, respectively, by HLA-DRB1*0103 and FCRL3-169 AG
- An increased susceptibility associated to the -169 T allele was found when MS patients.
- results of these meta-analyses provide no evidence that the FCRL3 -169TC polymorphism plays a significant role in determining rheumatoid arthritis risk in whites of European descent
- we found suggestive evidence for association of the FCRL3 -169CC genotype, corresponding to the susceptibility genotype for rheumatoid arthritis
- RA was associated with the C allele (odds ratio (OR) = 1.16, 95% CI 1.01 to 1.33) and the CC genotype (OR = 1.30, 95% CI 1.01 to 1.67) of the FCRL3 -169T>C SNP. Clinical subgroup analysis indicated that this was connected to the polyarticular subgroup.
- FCRL3 gene single nucleotide polymorphism was associated with rheumatoid arthritis
- Two SNPs (rs7528684/FCRL3_3 and rs7522061/N28D), which were in high linkage disequilibrium (r(2) = 0.87), differed between MS cases and controls.
- Genetic variations in FCRL3 were not associated with systemic lupus erythematosus in Chinese population.
- Fc receptor-like 1-5 molecules are similarly expressed in progressive and indolent clinical subtypes of B-cell chronic lymphocytic leukemia.
- The -110 G allele and haplotype CGCG of FCRL3 are positively associated with Behcet's disease(BD) in Chinese population. Haplotype ATCG might be protective haplotype for BD.