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Validated All-in-One™ qPCR Primer for TP53INP1(NM_033285.4) Search again
Product ID:
HQP186996
(click here to view gene annotation page)
Powered by BiozSpecies:
Human
Symbol:
Alias:
SIP, TP53DINP1, TP53INP1A, TP53INP1B, Teap, p53DINP1
Gene Description:
tumor protein p53 inducible nuclear protein 1
Target Gene Accession:
NM_033285.4(click here to view gene page)
Estimated Delivery:
Approximately 1-3 weeks, but may vary. Please email sales@genecopoeia.com or call 301-762-0888 to confirm ETA.
Important Note:
By default, qPCR primer pairs are designed to measure the expression level of the splice variant (accession number) you selected for this gene WITHOUT consideration of other possible variants of this gene. If this gene has multiple variants, and you would like to measure the expression levels of one particular variant, multiple variants, or all variants, please contact us for a custom service project at inquiry@genecopoeia.com.
Gene References into function
- Data show that induction of the stress-induced proteins (SIPs) SIP18 and SIP27, in human- and mouse-derived cell lines, is absent from cells with deleted, mutated or inactive p53, suggesting that regulation of SIP gene expression is dependent on p53.
- Assignment of tumor protein p53 induced nuclear protein 1 (TP53INP1) gene to human chromosome band 8q22 by in situ hybridization.
- TP53INP1s and HIPK2 could be partners in regulating p53 activity.
- TP53INP1s are functionally associated with p73 to regulate cell cycle progression and apoptosis.
- TP53INP1 protein negativity is significantly associated with aggressive pathological phenotypes of gastric cancer.
- TP531NP1 plays a significant role in the progression of anaplastic carcinoma or contributes to anaplastic transformation from papillary or follicular carcinoma, which is in sharp contrast to findings in previous in vitro and in vivo studies.
- PLZF upregulates apoptosis-inducer TP53INP1, ID1, and ID3 genes, and downregulates the apoptosis-inhibitor TERT gene
- The p53DINP1 mRna expression in the antral mucosa was significantly lower in the gastric cancer patients than in the chronic gastritis patients.
- P53DINP1 mRNA expression promotes Ser46 phophlrylation of p53, without finding a significant correlation between mRNA expression of p53AIP1.
- findings implicate a miR-93/miR-130b-TP53INP1 axis that affects the proliferation and survival of HTLV-1-infected/transformed cells