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Validated All-in-One™ qPCR Primer for PBRM1(NM_018313.5) Search again
Product ID:
HQP177477
(click here to view gene annotation page)
Powered by BiozSpecies:
Human
Symbol:
Alias:
BAF180, PB1, RCC, SMARCH1
Gene Description:
polybromo 1
Target Gene Accession:
NM_018313.5(click here to view gene page)
Estimated Delivery:
Approximately 1-3 weeks, but may vary. Please email sales@genecopoeia.com or call 301-762-0888 to confirm ETA.
Important Note:
By default, qPCR primer pairs are designed to measure the expression level of the splice variant (accession number) you selected for this gene WITHOUT consideration of other possible variants of this gene. If this gene has multiple variants, and you would like to measure the expression levels of one particular variant, multiple variants, or all variants, please contact us for a custom service project at inquiry@genecopoeia.com.
Gene References into function
- cDNA cloning; the hPB1 gene is located on chromosome 3p21, where the tumor suppressor genes for breast, lung and kidney cancers have been mapped
- We conclude that abnormalities of BAF180 are not frequently involved in the pathogenesis of lung cancer.
- Results indicate that single bromodomains bind specific acetyl-lysine sites within the histone 3 tail with sub-micromolar affinity.
- studies on how Pb1, and the broader class of bromodomain proteins, directs multisubunit chromatin remodeling complexes to specific acetyl-nucleosome sites
- BAF180 suppresses tumorigenesis, at least in part, through its ability to regulate p21.