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Validated All-in-One™ qPCR Primer for MED15(NM_001003891.3) Search again
Product ID:
HQP175604
(click here to view gene annotation page)
Species:
Human
Symbol:
Alias:
ARC105, CAG7A, CTG7A, PCQAP, TIG-1, TIG1, TNRC7
Gene Description:
mediator complex subunit 15
Target Gene Accession:
NM_001003891.3(click here to view gene page)
Estimated Delivery:
Approximately 1-3 weeks, but may vary. Please email sales@genecopoeia.com or call 301-762-0888 to confirm ETA.
Important Note:
By default, qPCR primer pairs are designed to measure the expression level of the splice variant (accession number) you selected for this gene WITHOUT consideration of other possible variants of this gene. If this gene has multiple variants, and you would like to measure the expression levels of one particular variant, multiple variants, or all variants, please contact us for a custom service project at inquiry@genecopoeia.com.
Summary
The protein encoded by this gene is a subunit of the multiprotein complexes PC2 and ARC/DRIP and may function as a transcriptional coactivator in RNA polymerase II transcription.
Gene References into function
- The protein encoded by this gene was identified as ARC105, a 105kDa component of the Activator-Recruited Cofactor (ARC) that is involved in mediating gene activation by several classes of transcriptional regulators.
- Methylation of TIG1 in prostatic neoplasms correlates with methylation of the retinoic acid receptor beta gene.
- Limited role of exon 7 PCQAP polymorphisms in the pathogenesis of schizophrenia.
- TIG1 gene Silencing by promoter hypermethylation is associated with nasopharyngeal carcinoma
- SREBPs use the evolutionarily conserved ARC105 (also called MED15) subunit to activate target genes
- results suggest that TRIM11, with the ubiquitin-proteasome pathway, regulates ARC105 function in TGFbeta signaling
