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Validated All-in-One™ qPCR Primer for JMJD6(NM_015167.3) Search again
Product ID:
HQP171008
(click here to view gene annotation page)
Powered by BiozSpecies:
Human
Symbol:
Alias:
PSR, PTDSR, PTDSR1
Gene Description:
jumonji domain containing 6, arginine demethylase and lysine hydroxylase
Target Gene Accession:
NM_015167.3(click here to view gene page)
Estimated Delivery:
Approximately 1-3 weeks, but may vary. Please email sales@genecopoeia.com or call 301-762-0888 to confirm ETA.
Important Note:
By default, qPCR primer pairs are designed to measure the expression level of the splice variant (accession number) you selected for this gene WITHOUT consideration of other possible variants of this gene. If this gene has multiple variants, and you would like to measure the expression levels of one particular variant, multiple variants, or all variants, please contact us for a custom service project at inquiry@genecopoeia.com.
Summary
This gene encodes a nuclear protein with a JmjC domain.
Gene References into function
- Elastase-mediated phosphatidylserine receptor cleavage impairs apoptotic cell clearance in cystic fibrosis and bronchiectasis.
- plays a major role in the clearance of apoptotic cells from the thymus.
- The mouse ortholog of Ptdsr is essential for the development and differentiation of multiple organs during embryogenesis but not for apoptotic cell clearance.
- Homomultimer of PS-R might be playing an important function as a scaffolding protein in the nucleus.
- study demonstrates that JMJD6 is a JmjC-containing iron- and 2-oxoglutarate-dependent dioxygenase that demethylates histone H3 at arginine 2 (H3R2) and histone H4 at arginine 3 (H4R3) in both biochemical and cell-based assays
- Jmjd6 is predicted to have a conserved enzymatic function as a classical non-heme, Fe(II)- and 2OG-dependent dioxygenase, and is closely related to the JmjC domain-containing proteins Jmjd4 and JFP6.