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Validated All-in-One™ qPCR Primer for CKAP4(NM_006825.4) Search again
Product ID:
HQP169345
(click here to view gene annotation page)
Species:
Human
Symbol:
Alias:
CLIMP-63, CLIMP63, ERGIC-63, p63
Gene Description:
cytoskeleton associated protein 4
Target Gene Accession:
NM_006825.4(click here to view gene page)
Estimated Delivery:
Approximately 1-3 weeks, but may vary. Please email sales@genecopoeia.com or call 301-762-0888 to confirm ETA.
Important Note:
By default, qPCR primer pairs are designed to measure the expression level of the splice variant (accession number) you selected for this gene WITHOUT consideration of other possible variants of this gene. If this gene has multiple variants, and you would like to measure the expression levels of one particular variant, multiple variants, or all variants, please contact us for a custom service project at inquiry@genecopoeia.com.
Gene References into function
- The p62/p63 protein was first identified because it is palmitoylated during mitosis.
- Purification and cloning of p62/p63.
- evidence to support the hypothesis that p63 is the functional tPA binding site on VSMC
- The ectrodactyly, absence of radius side part palm and split foot malformation are caused by the mutation of base pair at number 665 of the exon 5 of P63.
- CLIMP-63-mediated stable anchoring of the endoplasmic reticulum (ER) to microtubules is required to maintain the spatial distribution of the ER during interphase.
- is not responsible for autosomal-dominant amelogenesis imperfecta
- cytoskeleton-associated protein 4/p63 (CKAP4/p63), a type II transmembrane receptor, binds with high affinity to APF
- Olomoucine, a CDK inhibitor, up-regulates CKAP4, a cytoskeleton-linking membrane protein.
- Identification of CKAP4/p63 as a substrate of DHHC2, a putative tumor suppressor.
- CK MNF116 and p63 were useful in identifying squamous cell carcinomas with single cell infiltration.
- Results substantiate the role of P63 as a lung surfactant protein-A receptor protein localized on the surface of lung type II cells.
