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Validated All-in-One™ qPCR Primer for VGF(NM_003378.4) Search again
Product ID:
HQP162772
(click here to view gene annotation page)
Species:
Human
Symbol:
Alias:
SCG7, SgVII
Gene Description:
VGF nerve growth factor inducible
Target Gene Accession:
NM_003378.4(click here to view gene page)
Estimated Delivery:
Approximately 1-3 weeks, but may vary. Please email sales@genecopoeia.com or call 301-762-0888 to confirm ETA.
Important Note:
By default, qPCR primer pairs are designed to measure the expression level of the splice variant (accession number) you selected for this gene WITHOUT consideration of other possible variants of this gene. If this gene has multiple variants, and you would like to measure the expression levels of one particular variant, multiple variants, or all variants, please contact us for a custom service project at inquiry@genecopoeia.com.
Summary
This gene is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor.
Gene References into function
- Application of neurosecretory protein VGF biomarker model to current diagnostic criteria provides an objective biomarker pattern that identifies patients with amyotrophic lateral sclerosis.
- proVGF-related peptides are present in endocrine cells early during development and adulthood and increase in hyperplasia and tumors
- while Vgf may be a reliable biomarker of progression of muscle weakness in patients with ALS, restoration of Vgf expression in spinal cord motor neurons may therapeutically rescue spinal cord motorneurons against excitotoxic injury
