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Validated All-in-One™ qPCR Primer for RCVRN(NM_002903.3) Search again
By default, qPCR primer pairs are designed to measure the expression level of the splice variant (accession number) you selected for this gene WITHOUT consideration of other possible variants of this gene. If this gene has multiple variants, and you would like to measure the expression levels of one particular variant, multiple variants, or all variants, please contact us for a custom service project at inquiry@genecopoeia.com.
Summary
This gene encodes a member of the recoverin family of neuronal calcium sensors. The encoded protein contains three calcium-binding EF-hand domains and may prolong the termination of the phototransduction cascade in the retina by blocking the phosphorylation of photo-activated rhodopsin. Recoverin may be the antigen responsible for cancer-associated retinopathy. [provided by RefSeq].
Gene References into function
- recoverin has a pathological role in cancer-associated retinopathy
- There are cis-acting elements in the 5' non-coding region of the recoverin gene that are involved in the activation and suppression of gene expression.
- Human recoverin is expressed in SCLC cells cultured from an anti-recoverin antibody-negative patient with CAR. KK0206 might be important for further research on SCLC related retinopathy.
- A GRK1 region close to its C-terminus also seemed to be the binding site for S-modulin/recoverin.
