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Validated All-in-One™ qPCR Primer for PPM1G(NM_177983.3) Search again
Product ID:
HQP159055
(click here to view gene annotation page)
Species:
Human
Symbol:
Alias:
PP2CG, PP2CGAMMA, PPP2CG
Gene Description:
protein phosphatase, Mg2+/Mn2+ dependent 1G
Target Gene Accession:
NM_177983.3(click here to view gene page)
Estimated Delivery:
Approximately 1-3 weeks, but may vary. Please email sales@genecopoeia.com or call 301-762-0888 to confirm ETA.
Important Note:
By default, qPCR primer pairs are designed to measure the expression level of the splice variant (accession number) you selected for this gene WITHOUT consideration of other possible variants of this gene. If this gene has multiple variants, and you would like to measure the expression levels of one particular variant, multiple variants, or all variants, please contact us for a custom service project at inquiry@genecopoeia.com.
Summary
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways.
Gene References into function
- Functional study of the mouse homolog
- The degradation of p21(WAF1/CIP1) induced by PP2Cgamma was mediated in a proteasome-dependent manner.
- Protein phosphatase 2C gamma mediates histone dephosphorylation/exchange in response to DNA damage or checkpoint recovery in higher eukaryotes.
- PP2Cgamma modulates alternative splicing of specific pre-mRNAs coregulated by YB-1.
- an interplay between PPM1G and unrip determine compartment-specific phosphorylation patterns, localization, and function of the SMN complex
