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Validated All-in-One™ qPCR Primer for DDX6(NM_001257191.3) Search again
Product ID:
HQP152472
(click here to view gene annotation page)
Species:
Human
Symbol:
Alias:
HLR2, IDDILF, P54, RCK, Rck/p54
Gene Description:
DEAD-box helicase 6
Target Gene Accession:
NM_001257191.3(click here to view gene page)
Estimated Delivery:
Approximately 1-3 weeks, but may vary. Please email sales@genecopoeia.com or call 301-762-0888 to confirm ETA.
Important Note:
By default, qPCR primer pairs are designed to measure the expression level of the splice variant (accession number) you selected for this gene WITHOUT consideration of other possible variants of this gene. If this gene has multiple variants, and you would like to measure the expression levels of one particular variant, multiple variants, or all variants, please contact us for a custom service project at inquiry@genecopoeia.com.
Summary
This gene encodes a member of the DEAD box protein family.
Gene References into function
- Rck/p54 protein is possibly involved in the replication of HCV genomes in hepatocytes and in carcinogenesis of hepatocellular carcinoma.
- The Over-expression of RCK-p54 protein in HeLa cells caused growth inhibition and cell cycle arrest at G2/M with down-regulation of c-myc expression.
- Study shows that RCK/p54, a DEAD box helicase, interacts with Ago1 and Ago2, in active siRISC or miRISC from human cells; directly interacts with Ago1 and Ago2 in vivo, facilitates formation of P-bodies, and is a general repressor of translation.
- ataxin-2 interacts with the RNA helicase DDX6
- Structural basis for the mutually exclusive anchoring of P body components EDC3 and Tral to the DEAD box protein DDX6/Me31B.
