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Validated All-in-One™ qPCR Primer for SLC39A6(NM_012319.4) Search again
Powered by BiozBy default, qPCR primer pairs are designed to measure the expression level of the splice variant (accession number) you selected for this gene WITHOUT consideration of other possible variants of this gene. If this gene has multiple variants, and you would like to measure the expression levels of one particular variant, multiple variants, or all variants, please contact us for a custom service project at inquiry@genecopoeia.com.
Summary
Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A6 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM].
Gene References into function
- LIV-1 co-clusters with estrogen receptor alpha in microarray analysis of breast cancer biopsies.
- Review of LIV-1 and other LZT proteins.
- LIV-1, a member of the ZIP family of zinc transporters, is an integral plasma membrane protein that transports zinc into cells.
- Structure-function analysis of LIV-1.
- LIV-1 is coregulated with estrogen receptor in some breast cancers.
- data suggest that LIV-1 protein is a promising candidate for a novel marker for breast cancer patients with better outcome
- regulation of LIV-1 protein in human breast cancer xenografts
- Hence, our data provide the first evidence that LIV-1 mRNA is overexpressed in cervical cancer in situ and is involved in invasion of cervical cancer cells through targeting MAPK-mediated Snail and Slug expression.