|
ORF cDNA clones
|
CRISPR / TALEN
|
Lentivirus
|
AAV
|
TALE-TF
|
ORF knockin clones
|
|
Antibody
|
Proteins
|
miRNA target clones
|
qPCR primers
|
shRNA clones
|
miRNA products
|
Promoter clones
|
Validated All-in-One™ qPCR Primer for WWTR1(NM_001168278.2) Search again
Product ID:
HQP098028
(click here to view gene annotation page)
Species:
Human
Symbol:
Alias:
TAZ
Gene Description:
WW domain containing transcription regulator 1
Target Gene Accession:
NM_001168278.2(click here to view gene page)
Estimated Delivery:
Approximately 1-3 weeks, but may vary. Please email sales@genecopoeia.com or call 301-762-0888 to confirm ETA.
Important Note:
By default, qPCR primer pairs are designed to measure the expression level of the splice variant (accession number) you selected for this gene WITHOUT consideration of other possible variants of this gene. If this gene has multiple variants, and you would like to measure the expression levels of one particular variant, multiple variants, or all variants, please contact us for a custom service project at inquiry@genecopoeia.com.
Validated result:
Gene References into function
- coactivates Runx2-dependent gene transcription while repressing PPARgamma-dependent gene transcription; results indicate that TAZ functions as a molecular rheostat that modulates mesenchymal stem cell differentiation
- Decreased osteogenic potential of mesenchymal stem cells of myeloma patients was in part due to TNF-alpha suppressed TAZ expression.
- Seven placental transcripts characterize HELLP-syndrome.
- TAZ plays a role in the migration, invasion, and tumorigenesis of breast cancer cells and thus presents a novel target for the detection and treatment of breast cancer.
- Data demonstrate that in response to TGFbeta stimulation the transcriptional regulator TAZ binds heteromeric Smad2/3-4 complexes and is recruited to TGFbeta response elements.
