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Validated All-in-One™ qPCR Primer for CD24(NM_001291738.1) Search again
Product ID:
HQP070732
(click here to view gene annotation page)
Species:
Human
Symbol:
Alias:
CD24A
Gene Description:
CD24 molecule
Target Gene Accession:
NM_001291738.1(click here to view gene page)
Estimated Delivery:
Approximately 1-3 weeks, but may vary. Please email sales@genecopoeia.com or call 301-762-0888 to confirm ETA.
Important Note:
By default, qPCR primer pairs are designed to measure the expression level of the splice variant (accession number) you selected for this gene WITHOUT consideration of other possible variants of this gene. If this gene has multiple variants, and you would like to measure the expression levels of one particular variant, multiple variants, or all variants, please contact us for a custom service project at inquiry@genecopoeia.com.
Gene References into function
- The correlation between CD24 expression and invasiveness was calculated to be highly significant
- is expressed in ovarian cancer and is a new independent prognostic marker of patient survival
- assessment of expression on bone marrow neutrophilic granulocytes: a marker for myelocytic leukemia staging
- CD24 mediates apoptosis in precursor-B acute lymphoblastic leukemia cell lines in the pro-B and pre-B stages accompanying activation of multiple caspases.
- high level of CD24 expression is associated with nonsmall cell lung cancer
- N-glycans of the mouse glycoprotein HSA and its human analogue CD24 from lymphoblastoma, neuroblastoma and astrocytoma cell lines as well as from mouse brain homogenate were analysed and compared to each other
- Deficiency in function of the CD4(+)CD25(+) T-cell population may influence the pathogenesis of type 1 diabetes.
- Overexpression of CD24 is associated with intrahepatic cholangiocarcinoma
- CD24 constitutes an important molecular marker for various epithelial neoplasms
- CD24 is commonly up-regulated in colorectal cancer and is a new independent prognostic marker.
- CD24 expression was upregulated in chordoma, while it was absent in chondrosarcoma
- CD80-CD24 molecule spontaneously incorporated onto cell membrane through its glycolipid anchor suggesting that this hybrid costimulatory molecule can be used in protein transfer to develop effective cancer vaccines
- Over-expression of CD24 is associated with primary and relapsed ovarian cancer
- CD24 is overexpressed in the colonic mucosa, already at an early stage of carcinogenesis. It may be a useful target for early detection and in CRC therapy.
- The study documented that cytoplasmic-membranous expression of CD24 represented an extremely strong unfavourable prognostic factor in breast cancer.
- association between the V/V genotype at aa 57 of this gene and multiple sclerosis in Basque natives
- CD24 regulates E-cadherin and TGF-beta3 expression in cultured oral epithelial cells
- A destabilizing dinucleotide deletion in the 3' UTR of CD24 mRNA conveys significant protection against both multiple sclerosis and systemic lupus erythematosus.
- CD24 is modulated by IGFBP-2 and contributes to IGFBP-2-enhanced invasiveness of glioblastoma cells
- CD24 deficient breast cancer cells are successful in overcoming an engraftment incompatibility that exists when injecting human cells into mouse adipose tissue.
- CD24 is not essential for exosome formation or release but may be a convenient exosome marker. Our studies suggest that exosomal secretion from the embryonic kidney could play a biological role at the fetal-maternal interphase.
- findings suggest that the CD24 A57V polymorphism plays a role in susceptibility to systemic lupus erythematosus in a Spanish population
- Study identifies CD24 and EpCAM as cargo proteins of exosomes of cultured ovarian cancer cell lines and malignant ascites.
- A decrease in CD4+CD25+ T cell numbers in mitral stenosis patients might suggest a role for cellular autoimmunity in a smoldering rheumatic process.
- High CD24 is associated with neoplasm invasiveness in breast cancer
- CD24 acts as a gate-keeper for lipid rafts, thereby regulating the activity of integrins and other proteins
- There is a potential role for the CD24 gene in the susceptibility to giant cell arteritis in our population in Spain.
- CD24 expression in clear cell renal cell carcinoma may be associated with high nuclear grade, large tumor size, and shortened progression-free survival
- CD24 is repressed by estrogen and this repression is a direct transcriptional effect depending on ER alpha and histone deacetylases.
- As a putative new oncogene that is overexpressed in gastrointestinal malignancies early in the carcinogenesis process, CD24 my be a potential target for early intervention in the prevention and treatment of cancer.
- low expression of CD24 may cause the enhanced immune reaction and could play a role in the abnormal development of placenta in pre-eclampsia
- In breast tissue, CD44(+)/CD24(-/low) tumor cells seem to be associated with lack of lymph node metastasis and a tendency toward an increase of the relapse-free survival of the patients.
- analysis of CD44 and CD24 expression in breast tumors
- MOG specific T cells (2D2) will escape clonal deletion and can result in spontaneous EAE. CD24 deficient MOG specific T cells (2D2CD24KO) are depleted from the thymic compartment, and the T cells in the periphery are CD4 negative.
- CD44 but not CD24 may be involved in the breast cancer pathway and is a target for oncolytic virotherapy
- CD24 appears to be highly expressed in a large variety of human cancers and to contribute to the acceleration of tumor growth and metastases shedding by binding to platelet (P)-selectin
