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Validated All-in-One™ qPCR Primer for FRS2(NM_006654.4) Search again
Product ID:
HQP054010
(click here to view gene annotation page)
Powered by BiozSpecies:
Human
Symbol:
Alias:
FRS1A, FRS2A, FRS2alpha, SNT, SNT-1, SNT1
Gene Description:
fibroblast growth factor receptor substrate 2
Target Gene Accession:
NM_006654.4(click here to view gene page)
Estimated Delivery:
Approximately 1-3 weeks, but may vary. Please email sales@genecopoeia.com or call 301-762-0888 to confirm ETA.
Important Note:
By default, qPCR primer pairs are designed to measure the expression level of the splice variant (accession number) you selected for this gene WITHOUT consideration of other possible variants of this gene. If this gene has multiple variants, and you would like to measure the expression levels of one particular variant, multiple variants, or all variants, please contact us for a custom service project at inquiry@genecopoeia.com.
Gene References into function
- FRS2 PTB domain conformation regulates interactions with divergent neurotrophic receptors
- FRS2 has a role in fibroblast growth factor-2-induced signaling
- findings support a broader role of FRS2 in EGFR-controlled signaling pathways in A-431 cells and provide insight into a molecular mechanism for ligand-stimulated feedback regulation with FRS2 as a central regulatory switch point
- FRS2-dependent SRC activation is required for FGFR-induced phosphorylation of Sprouty and suppression of ERK activity
- Bisindolylmaleimide I does not inhibit FGF2-induced tyrosine phosphorylation of Frs2.
- an important function for FRS2 is to concentrate RET in membrane foci, leading to an engagement of specific signaling complexes localized in these membrane domains