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Validated All-in-One™ qPCR Primer for BST2(NM_004335.3) Search again
Product ID:
HQP017844
(click here to view gene annotation page)
Species:
Human
Symbol:
Alias:
CD317, HM1.24, TETHERIN
Gene Description:
bone marrow stromal cell antigen 2
Target Gene Accession:
NM_004335.3(click here to view gene page)
Estimated Delivery:
Approximately 1-3 weeks, but may vary. Please email sales@genecopoeia.com or call 301-762-0888 to confirm ETA.
Important Note:
By default, qPCR primer pairs are designed to measure the expression level of the splice variant (accession number) you selected for this gene WITHOUT consideration of other possible variants of this gene. If this gene has multiple variants, and you would like to measure the expression levels of one particular variant, multiple variants, or all variants, please contact us for a custom service project at inquiry@genecopoeia.com.
Validated result:
Summary
Bone marrow stromal cells are involved in the growth and development of B-cells. The specific function of the protein encoded by the bone marrow stromal cell antigen 2 is undetermined; however, this protein may play a role in pre-B-cell growth and in rheumatoid arthritis. [provided by RefSeq].
Gene References into function
- CD317 expression correlated with, and induced, a requirement for Vpu during HIV-1 and murine leukaemia virus particle release
- CD317, a tetherin, is associated with antiviral activity; tetherin expression correlates with a requirement for the antiviral antagonist Vpu during HIV-1 virus particle release.
- Interferon-alpha enhances BST2 expression and the antitumor activity of anti-CD317 monoclonal antibody in renal cell carcinoma xenogfraft models.
- Tetherin inhibits the release of Lassa and Marburg virus from host cells.
