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Validated All-in-One™ qPCR Primer for PPP3R1(NM_000945.3) Search again
Product ID:
HQP014356
(click here to view gene annotation page)
Powered by BiozSpecies:
Human
Symbol:
Alias:
CALNB1, CNB, CNB1
Gene Description:
protein phosphatase 3 regulatory subunit B, alpha
Target Gene Accession:
NM_000945.3(click here to view gene page)
Estimated Delivery:
Approximately 1-3 weeks, but may vary. Please email sales@genecopoeia.com or call 301-762-0888 to confirm ETA.
Important Note:
By default, qPCR primer pairs are designed to measure the expression level of the splice variant (accession number) you selected for this gene WITHOUT consideration of other possible variants of this gene. If this gene has multiple variants, and you would like to measure the expression levels of one particular variant, multiple variants, or all variants, please contact us for a custom service project at inquiry@genecopoeia.com.
Validated result:
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| A | B |
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Each All-in-One™ qPCR Primer is experimentally validated to yield a single dissociation curve peak and to generate a single amplification of the correct size for the targeted gene. A cDNA Pool, containing reverse transcript products of 8 different human tissue total RNA(Liver, Testis,Muscle,Thyroid,Brain,Spleen,Stomach,Small Intestine)),was used as the qPCR validation template. qPCR was performed using 0.2 µM primer with 2XAll-in-One™ qPCR Mix (Catalog#: QP001,QP002,QP004,QP005). Reactions were incubated for 10min. at 95°C, followed by 40 cycles of 95°C for 10 sec.; 60°C, 20 sec. and 72°C, 15sec. using Bio-Rad iQ5™ Instrument. At the end of the last cycle, temperature was increased from 72 to 95°C to produce a melting curve. Panel A: Validated Result for Amplification Curve; Panel B: Validated Result for Melting Curve. |
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Gene References into function
- these data imply novel functions of calcineurin and NF-kappaB for successful IS maturation.
- Endothelin 1 (ET-1) activates calcineurin and causes nuclear translocation of NFATc1, implicating the pathway in the ET-1-mediated stimulation of osteoblasts.
- IGF-1/PPP3R1 gene polymorphisms influence muscle phenotypic responses to strength training in both black and white older men and women.
- Data show that the calcineurin pathway is activated in hypertrophic myocardium as demonstrated by increased calcineurin activity and expression of calcineurin A-beta and B, and GATA-4, and a shift of cytoplasmic NFAT-3 into the nucleus.
- analysis of the secondary structure of calcineurin regulatory region and conformational change induced by calcium/calmodulin binding
- No significant differences in calcineurin b expression was observed between patients with schizophrenia and normal controls
- Overexpression of calcineurin B subunit enhances the oncogenic potential of HEK293 cells
- Study found that although calcineurin/NFAT signalling pathway has an important, non-redundant role in the regulation of lymphocyte developmental checkpoints, it is not essential for the development of blood myeloid lineages.
- CNB gene 5I/5D polymorphism is associated with the risk of left ventricular hypertrophy and physical performance of athletes.
- A conserved docking surface on calcineurin mediates interaction with substrates and immunosuppressants.