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Validated All-in-One™ qPCR Primer for TBX22(NM_016954.2) Search again
Product ID:
HQP012271
(click here to view gene annotation page)
Species:
Human
Symbol:
Alias:
ABERS, CLPA, CPX, TBXX, dJ795G23.1
Gene Description:
T-box transcription factor 22
Target Gene Accession:
NM_016954.2(click here to view gene page)
Estimated Delivery:
Approximately 1-3 weeks, but may vary. Please email sales@genecopoeia.com or call 301-762-0888 to confirm ETA.
Important Note:
By default, qPCR primer pairs are designed to measure the expression level of the splice variant (accession number) you selected for this gene WITHOUT consideration of other possible variants of this gene. If this gene has multiple variants, and you would like to measure the expression levels of one particular variant, multiple variants, or all variants, please contact us for a custom service project at inquiry@genecopoeia.com.
Validated result:
Summary
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box.
Gene References into function
- Craniofacial expression of human and murine TBX22 correlates with the cleft palate and ankyloglossia (CPX) phenotype observed in CPX patients.
- Four novel TBX22 splice site mutations in North American and Brazilian cleft palate families.
- TBX22 is a target for the small ubiquitin-like modifier SUMO-1 and this modification is required for TBX22 repressor activity.
- TBX22 mutations are responsible for a significant proportion of Thai non-syndromic cleft palate cases.
