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Validated All-in-One™ qPCR Primer for KCNK18(NM_181840.1) Search again
Product ID:
HQP009189
(click here to view gene annotation page)
Powered by BiozSpecies:
Human
Symbol:
Alias:
K2p18.1, MGR13, TRESK, TRESK-2, TRESK2, TRIK
Gene Description:
potassium two pore domain channel subfamily K member 18
Target Gene Accession:
NM_181840.1(click here to view gene page)
Estimated Delivery:
Approximately 1-3 weeks, but may vary. Please email sales@genecopoeia.com or call 301-762-0888 to confirm ETA.
Important Note:
By default, qPCR primer pairs are designed to measure the expression level of the splice variant (accession number) you selected for this gene WITHOUT consideration of other possible variants of this gene. If this gene has multiple variants, and you would like to measure the expression levels of one particular variant, multiple variants, or all variants, please contact us for a custom service project at inquiry@genecopoeia.com.
Gene References into function
- TRESK is a novel two-pore domain K+ channel that may set the resting membrane potential of cells in the spinal cord
- TRESK is activated by increased cytoplasmic calcium concentration, calcineurin being involved in the regulation; Serine 276 was identified as the major functional target of calcineurin in TRESK
- TRESK-2 is a functional member of the K(2P) channel family and contributes to the background K+ conductance in many types of cells [TRESK-2]
- Because 14-3-3 proteins are ubiquitous, they are expected to control the duration of calcineurin-mediated TRESK activation in all the cell types that express the channel, depending on the phosphorylation state of serine 264.
- background K+ currents expressed in Jurkat cells are mediated by TRESK channels