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Validated All-in-One™ qPCR Primer for CUL9(NM_015089.3) Search again
Product ID:
HQP005770
(click here to view gene annotation page)
Species:
Human
Symbol:
Alias:
H7AP1, PARC
Gene Description:
cullin 9
Target Gene Accession:
NM_015089.3(click here to view gene page)
Estimated Delivery:
Approximately 1-3 weeks, but may vary. Please email sales@genecopoeia.com or call 301-762-0888 to confirm ETA.
Important Note:
By default, qPCR primer pairs are designed to measure the expression level of the splice variant (accession number) you selected for this gene WITHOUT consideration of other possible variants of this gene. If this gene has multiple variants, and you would like to measure the expression levels of one particular variant, multiple variants, or all variants, please contact us for a custom service project at inquiry@genecopoeia.com.
Validated result:
Gene References into function
- Parc, a Parkin-like ubiquitin ligase,is a critical regulator in controlling p53 subcellular cytoplasmic localization and subsequent function.
- FUBP1 is an authentic substrate of Parkin that might play an important role in development of Parkinson disease pathology along with aminoacyl-tRNA synthetase interacting multifunctional protein type 2
- CPH domain interaction surface of p53 resides in the tetramerization domain and is formed by residues contributed by at least two subunits
- PARC and CUL7 subcomplexes exhibit E3 ubiquitin ligase activity in vitro.
- These studies suggest that PARC-interacting peptides are promising candidates for the enhancement of p53-dependent apoptosis in tumors with wt cytoplasmic p53.
