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Validated All-in-One™ qPCR Primer for PLK2(NM_006622.3) Search again
Product ID:
HQP000904
(click here to view gene annotation page)
Species:
Human
Symbol:
Alias:
SNK, hPlk2, hSNK
Gene Description:
polo like kinase 2
Target Gene Accession:
NM_006622.3(click here to view gene page)
Estimated Delivery:
Approximately 1-3 weeks, but may vary. Please email sales@genecopoeia.com or call 301-762-0888 to confirm ETA.
Important Note:
By default, qPCR primer pairs are designed to measure the expression level of the splice variant (accession number) you selected for this gene WITHOUT consideration of other possible variants of this gene. If this gene has multiple variants, and you would like to measure the expression levels of one particular variant, multiple variants, or all variants, please contact us for a custom service project at inquiry@genecopoeia.com.
Validated result:
Summary
Serum-inducible kinase is a member of the 'polo' family of serine/threonine protein kinases that have a role in normal cell division.[supplied by OMIM].
Gene References into function
- there is a mitotic checkpoint wherein p53-dependent activation of Snk/Plk2 prevents mitotic catastrophe following spindle damage
- hVPS18 may play an important role in regulation of SNK activity through its ubiquitin ligase
- Calcipotriol affects proliferation of keratinocytes by decreasing the expression of EGR1 and PLK2
- is a novel target of ERRgamma, and their interaction is crucial for cancer cell proliferation
- increased cell death observed after aphidicolin treatment and release in Plk2-deficient cells may result from both higher levels of replication stress-induced DNA damage and a dysfunctional S-phase checkpoint
- Plk2 mediated centriole duplication is dependent on Plk4 function
